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Search results 1 to 100 out of 107 for Def6

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Type Details Score
Gene
50619 | DEF6
Type: gene
Organism: human
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Gene
608163 | DEF6
Type: gene
Organism: dog, domestic
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Gene
516457 | DEF6
Type: gene
Organism: cattle
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Gene
718845 | DEF6
Type: gene
Organism: macaque, rhesus
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Gene
309642 | Def6
Type: gene
Organism: rat
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Gene
462636 | DEF6
Type: gene
Organism: chimpanzee
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Gene
419893 | DEF6
Type: gene
Organism: chicken
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Gene
100498543 | def6
Type: gene
Organism: frog, western clawed
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Protein Coding Gene
MGI:1346328 | Def6
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
28314855 | J:247787
First Author: Binder N
Year: 2017
Journal: J Immunol
Title: Def6 Restrains Osteoclastogenesis and Inflammatory Bone Resorption.
Volume: 198
Issue: 9
Pages: 3436-3447
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Publication
32709659 | J:301498
First Author: Popović J
Year: 2020
Journal: J Immunol
Title: Control of GM-CSF-Dependent Dendritic Cell Differentiation and Maturation by DEF6 and SWAP-70.
Volume: 205
Issue: 5
Pages: 1306-1317
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Publication
33373293 | J:300694
   
First Author: Deng Z
Year: 2020
Journal: Elife
Title: Def6 regulates endogenous type-I interferon responses in osteoblasts and suppresses osteogenesis.
Volume: 9
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Publication
19915062 | J:157385
First Author: Canonigo-Balancio AJ
Year: 2009
Journal: J Immunol
Title: SLAT/Def6 plays a critical role in the development of Th17 cell-mediated experimental autoimmune encephalomyelitis.
Volume: 183
Issue: 11
Pages: 7259-67
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Publication
23197258 | J:190836
First Author: Feau S
Year: 2013
Journal: J Immunol
Title: SLAT regulates CD8+ T cell clonal expansion in a Cdc42- and NFAT1-dependent manner.
Volume: 190
Issue: 1
Pages: 174-83
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Publication
27561029 | J:251153
First Author: Ripich T
Year: 2016
Journal: PLoS One
Title: SWEF Proteins Distinctly Control Maintenance and Differentiation of Hematopoietic Stem Cells.
Volume: 11
Issue: 8
Pages: e0161060
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Publication
34376664 | J:314345
First Author: Ricker E
Year: 2021
Journal: Nat Commun
Title: Altered function and differentiation of age-associated B cells contribute to the female bias in lupus mice.
Volume: 12
Issue: 1
Pages: 4813
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Publication
26544714 | J:244000
First Author: Manni M
Year: 2015
Journal: PLoS One
Title: IRF4-Dependent and IRF4-Independent Pathways Contribute to DC Dysfunction in Lupus.
Volume: 10
Issue: 11
Pages: e0141927
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Publication
22370718 | J:182699
First Author: Biswas PS
Year: 2012
Journal: J Exp Med
Title: Dual regulation of IRF4 function in T and B cells is required for the coordination of T-B cell interactions and the prevention of autoimmunity.
Volume: 209
Issue: 3
Pages: 581-96
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Publication
28811467 | J:254902
First Author: Yi W
Year: 2017
Journal: Nat Commun
Title: The mTORC1-4E-BP-eIF4E axis controls de novo Bcl6 protein synthesis in T cells and systemic autoimmunity.
Volume: 8
Issue: 1
Pages: 254
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Publication
29483597 | J:281492
First Author: Manni M
Year: 2018
Journal: Nat Immunol
Title: Regulation of age-associated B cells by IRF5 in systemic autoimmunity.
Volume: 19
Issue: 4
Pages: 407-419
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Protein Coding Gene
MGP_CAROLIEiJ_G0021315 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0023435 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0023393 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0023358 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0023398 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0023159 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_1346328 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0023840 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0022660 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0023133 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0023264 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0023234 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0023342 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0023252 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0023882 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0022410 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0022722 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0023633 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0022228 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
12648457 | J:82492
First Author: Tanaka Y
Year: 2003
Journal: Immunity
Title: SWAP-70-like adapter of T cells, an adapter protein that regulates early TCR-initiated signaling in Th2 lineage cells.
Volume: 18
Issue: 3
Pages: 403-14
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Publication
17657315 | J:123956
First Author: Bécart S
Year: 2007
Journal: J Clin Invest
Title: SLAT regulates Th1 and Th2 inflammatory responses by controlling Ca2+/NFAT signaling.
Volume: 117
Issue: 8
Pages: 2164-75
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Publication
19251698 | J:149853
First Author: Mehta H
Year: 2009
Journal: J Biol Chem
Title: Adaptor protein SLAT modulates Fcgamma receptor-mediated phagocytosis in murine macrophages.
Volume: 284
Issue: 18
Pages: 11882-91
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Publication
22815639 | J:191598
 
First Author: Vistica BP
Year: 2012
Journal: Mol Vis
Title: SLAT/Def6 plays a critical role in the pathogenic process of experimental autoimmune uveitis (EAU).
Volume: 18
Pages: 1858-64
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GXD Expression
GXD Expression
     
Probe: MGI:1347500
Assay Type: Northern blot
Annotation Date: 1999-11-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603910
Stage: TS10
Assay Id: MGI:1347504
Age: embryonic day 7.0
Specimen Label: day 7
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:1347500
Assay Type: Northern blot
Annotation Date: 1999-11-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603918
Stage: TS18
Assay Id: MGI:1347504
Age: embryonic day 11.0
Specimen Label: day 11
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:1347500
Assay Type: Northern blot
Annotation Date: 1999-11-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603923
Stage: TS23
Assay Id: MGI:1347504
Age: embryonic day 15.0
Specimen Label: day 15
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
     
Probe: MGI:1347500
Assay Type: Northern blot
Annotation Date: 1999-11-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603925
Stage: TS25
Assay Id: MGI:1347504
Age: embryonic day 17.0
Specimen Label: day 17
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
     
Probe: MGI:1347500
Assay Type: Northern blot
Annotation Date: 1999-11-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:1347534
Age: postnatal adult
Specimen Label: heart
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:1347500
Assay Type: Northern blot
Annotation Date: 1999-11-29
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:1347534
Age: postnatal adult
Specimen Label: brain
Detected: false
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:1347500
Assay Type: Northern blot
Annotation Date: 1999-11-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:1347534
Age: postnatal adult
Specimen Label: spleen
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
     
Probe: MGI:1347500
Assay Type: Northern blot
Annotation Date: 1999-11-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672828
Stage: TS28
Assay Id: MGI:1347534
Age: postnatal adult
Specimen Label: lung
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
     
Probe: MGI:1347500
Assay Type: Northern blot
Annotation Date: 1999-11-29
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:1347534
Age: postnatal adult
Specimen Label: liver
Detected: false
Specimen Num: 5
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GXD Expression
GXD Expression
     
Probe: MGI:1347500
Assay Type: Northern blot
Annotation Date: 1999-11-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3557728
Stage: TS28
Assay Id: MGI:1347534
Age: postnatal adult
Specimen Label: muscle
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
     
Probe: MGI:1347500
Assay Type: Northern blot
Annotation Date: 1999-11-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:1347534
Age: postnatal adult
Specimen Label: kidney
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
     
Probe: MGI:1347500
Assay Type: Northern blot
Annotation Date: 1999-11-29
Strength: Absent
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:1347534
Age: postnatal adult
Specimen Label: testis
Detected: false
Specimen Num: 8
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GXD Expression
GXD Expression
 
Probe: MGI:939224
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1752323
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824277
Age: embryonic day 14.5
Image: euxassay_001680_10
Specimen Label: euxassay_001680_10
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:939224
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1752323
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824277
Age: embryonic day 14.5
Image: euxassay_001680_11
Specimen Label: euxassay_001680_11
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:939224
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1752323
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824277
Age: embryonic day 14.5
Image: euxassay_001680_12
Specimen Label: euxassay_001680_12
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
 
Probe: MGI:939224
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1752323
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824277
Age: embryonic day 14.5
Image: euxassay_001680_13
Specimen Label: euxassay_001680_13
Detected: true
Specimen Num: 4
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Publication
24096077 | J:202823
First Author: Worthmann K
Year: 2013
Journal: Am J Pathol
Title: Def-6, a novel regulator of small GTPases in podocytes, acts downstream of atypical protein kinase C (aPKC) λ/ι.
Volume: 183
Issue: 6
Pages: 1945-59
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Publication
19074553 | J:146059
First Author: Chen Q
Year: 2009
Journal: J Leukoc Biol
Title: Regulation of TLR4-mediated signaling by IBP/Def6, a novel activator of Rho GTPases.
Volume: 85
Issue: 3
Pages: 539-43
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Publication
16470246 | J:106469
First Author: Fanzo JC
Year: 2006
Journal: J Clin Invest
Title: Loss of IRF-4-binding protein leads to the spontaneous development of systemic autoimmunity.
Volume: 116
Issue: 3
Pages: 703-14
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Publication
18976935 | J:143773
First Author: Bécart S
Year: 2008
Journal: Immunity
Title: Tyrosine-phosphorylation-dependent translocation of the SLAT protein to the immunological synapse is required for NFAT transcription factor activation.
Volume: 29
Issue: 5
Pages: 704-19
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Publication
35438841 | J:336755
First Author: Chen Z
Year: 2022
Journal: Arthritis Rheumatol
Title: Interleukin-13 Receptor α1-Mediated Signaling Regulates Age-Associated/Autoimmune B Cell Expansion and Lupus Pathogenesis.
Volume: 74
Issue: 9
Pages: 1544-1555
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Publication
25270259 | J:259968
First Author: Fos C
Year: 2014
Journal: Sci Signal
Title: Association of the EF-hand and PH domains of the guanine nucleotide exchange factor SLAT with IP₃ receptor 1 promotes Ca²⁺ signaling in T cells.
Volume: 7
Issue: 345
Pages: ra93
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Publication
17403664 | J:122659
First Author: Samson T
Year: 2007
Journal: J Biol Chem
Title: Def-6, a guanine nucleotide exchange factor for Rac1, interacts with the skeletal muscle integrin chain alpha7A and influences myoblast differentiation.
Volume: 282
Issue: 21
Pages: 15730-42
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Publication
20697158 | J:165281
First Author: Biswas PS
Year: 2010
Journal: J Clin Invest
Title: Phosphorylation of IRF4 by ROCK2 regulates IL-17 and IL-21 production and the development of autoimmunity in mice.
Volume: 120
Issue: 9
Pages: 3280-95
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Publication
19062315 | J:142684
First Author: Chen Q
Year: 2008
Journal: Immunity
Title: IRF-4-binding protein inhibits interleukin-17 and interleukin-21 production by controlling the activity of IRF-4 transcription factor.
Volume: 29
Issue: 6
Pages: 899-911
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Publication
10460589 | J:56735
First Author: Hotfilder M
Year: 1999
Journal: Br J Haematol
Title: Def-2, -3, -6 and -8, novel mouse genes differentially expressed in the haemopoietic system.
Volume: 106
Issue: 2
Pages: 335-44
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Publication
23793062 | J:205441
First Author: Liang Y
Year: 2013
Journal: Nat Immunol
Title: The lymphoid lineage-specific actin-uncapping protein Rltpr is essential for costimulation via CD28 and the development of regulatory T cells.
Volume: 14
Issue: 8
Pages: 858-66
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Publication
- | J:175295
     
First Author: Mouse Genome Informatics and the Wellcome Trust Sanger Institute Mouse Genetics Project (MGP)
Year: 2011
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the Wellcome Trust Sanger Institute (WTSI) Mouse Resources Portal
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Publication
30973865 | J:274872
First Author: Ingham NJ
Year: 2019
Journal: PLoS Biol
Title: Mouse screen reveals multiple new genes underlying mouse and human hearing loss.
Volume: 17
Issue: 4
Pages: e3000194
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Publication
- | J:80001
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: FANTOM2 Data Curation in Mouse Genome Informatics
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Publication
- | J:136110
     
First Author: Velocigene
Year: 2008
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals)
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Publication
- | J:155845
     
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
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Publication
- | J:157065
     
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
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Publication
18799693 | J:142754
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
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Publication
- | J:342604
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
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Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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