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Search results 1 to 100 out of 122 for Defa3

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0.041s
Type Details Score
Gene
Type: gene
Organism: human
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Publication
First Author: Chen Q
Year: 2019
Journal: Proc Natl Acad Sci U S A
Title: Increased gene copy number of DEFA1/DEFA3 worsens sepsis by inducing endothelial pyroptosis.
Volume: 116
Issue: 8
Pages: 3161-3170
Publication
First Author: Selsted ME
Year: 1992
Journal: J Cell Biol
Title: Enteric defensins: antibiotic peptide components of intestinal host defense.
Volume: 118
Issue: 4
Pages: 929-36
Publication
First Author: Huttner KM
Year: 1994
Journal: Genomics
Title: Structure and diversity of the murine cryptdin gene family.
Volume: 19
Issue: 3
Pages: 448-53
Publication
First Author: Ouellette AJ
Year: 1994
Journal: Infect Immun
Title: Mouse Paneth cell defensins: primary structures and antibacterial activities of numerous cryptdin isoforms.
Volume: 62
Issue: 11
Pages: 5040-7
Publication
First Author: Ayabe T
Year: 2000
Journal: Nat Immunol
Title: Secretion of microbicidal alpha-defensins by intestinal Paneth cells in response to bacteria.
Volume: 1
Issue: 2
Pages: 113-8
Publication  
First Author: Amid C
Year: 2009
Journal: BMC Genomics
Title: Manual annotation and analysis of the defensin gene cluster in the C57BL/6J mouse reference genome.
Volume: 10
Pages: 606
Publication        
First Author: Haiming Tang, Dustin Ebert, Matthias Blum, Robert Finn, Paul Thomas
Year: 2023
Title: TreeGrafter-generated GO annotations
Publication      
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Mouse Synonym Curation
Publication        
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
Publication        
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
Publication        
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Publication
First Author: Jia HP
Year: 2000
Journal: J Biol Chem
Title: A novel murine beta -defensin expressed in tongue, esophagus, and trachea.
Volume: 275
Issue: 43
Pages: 33314-20
Publication
First Author: Ayabe T
Year: 2002
Journal: J Biol Chem
Title: Activation of Paneth cell alpha-defensins in mouse small intestine.
Volume: 277
Issue: 7
Pages: 5219-28
Publication  
First Author: Nyeng P
Year: 2008
Journal: BMC Dev Biol
Title: FGF10 maintains distal lung bud epithelium and excessive signaling leads to progenitor state arrest, distalization, and goblet cell metaplasia.
Volume: 8
Pages: 2
Publication        
First Author: International Committee on Standardized Genetic Nomenclature for Mice
Year: 1993
Title: Nomenclature rule change to delete hyphens and parentheses from mouse locus symbols
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication      
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
Publication        
First Author: Mouse Genome Informatics Scientfic Curators
Year: 2013
Title: Curated associations of genes in MGI and UniProt sequence records
Allele
Name: defensin, alpha, 3; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Ouellette AJ
Year: 1989
Journal: J Cell Biol
Title: Developmental regulation of cryptdin, a corticostatin/defensin precursor mRNA in mouse small intestinal crypt epithelium.
Volume: 108
Issue: 5
Pages: 1687-95
Publication
First Author: Ouellette AJ
Year: 1992
Journal: FEBS Lett
Title: Purification and primary structure of murine cryptdin-1, a Paneth cell defensin.
Volume: 304
Issue: 2-3
Pages: 146-8
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Publication
First Author: Garabedian EM
Year: 1997
Journal: J Biol Chem
Title: Examining the role of Paneth cells in the small intestine by lineage ablation in transgenic mice.
Volume: 272
Issue: 38
Pages: 23729-40
Publication
First Author: Ouellette AJ
Year: 1989
Journal: Genomics
Title: Localization of the cryptdin locus on mouse chromosome 8.
Volume: 5
Issue: 2
Pages: 233-9
Publication
First Author: Ouellette AJ
Year: 1996
Journal: FASEB J
Title: Paneth cell defensins: endogenous peptide components of intestinal host defense.
Volume: 10
Issue: 11
Pages: 1280-9
Publication
First Author: Darmoul D
Year: 1997
Journal: Am J Physiol
Title: Cryptdin gene expression in developing mouse small intestine.
Volume: 272
Issue: 1 Pt 1
Pages: G197-206
Publication
First Author: Hughes AL
Year: 1999
Journal: Cell Mol Life Sci
Title: Evolutionary diversification of the mammalian defensins.
Volume: 56
Issue: 1-2
Pages: 94-103
Publication
First Author: Abu-Fanne R
Year: 2019
Journal: Blood
Title: Neutrophil α-defensins promote thrombosis in vivo by altering fibrin formation, structure, and stability.
Volume: 133
Issue: 5
Pages: 481-493
GXD Expression      
Probe: MGI:4357896
Assay Type: RT-PCR
Annotation Date: 2009-09-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3287425
Stage: TS25
Assay Id: MGI:4358224
Age: embryonic day 17.5
Specimen Label: Int
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:4357896
Assay Type: RT-PCR
Annotation Date: 2009-09-18
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1702125
Stage: TS25
Assay Id: MGI:4358224
Age: embryonic day 17.5
Specimen Label: St
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:4352716
Assay Type: RT-PCR
Annotation Date: 2009-08-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3276422
Stage: TS22
Assay Id: MGI:4352912
Age: embryonic day 14.5
Image: S1
Specimen Label: E14.5 WT
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:4352716
Assay Type: RT-PCR
Annotation Date: 2009-08-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3276422
Stage: TS22
Assay Id: MGI:4352912
Age: embryonic day 14.5
Image: S1
Specimen Label: E14.5 HE
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:4352716
Assay Type: RT-PCR
Annotation Date: 2009-08-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3276422
Stage: TS22
Assay Id: MGI:4352912
Age: embryonic day 14.5
Image: S1
Specimen Label: E14.5 KO
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:4352716
Assay Type: RT-PCR
Annotation Date: 2009-08-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3276423
Stage: TS23
Assay Id: MGI:4352912
Age: embryonic day 15.5
Image: S1
Specimen Label: E15.5 WT
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:4352716
Assay Type: RT-PCR
Annotation Date: 2009-08-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3276423
Stage: TS23
Assay Id: MGI:4352912
Age: embryonic day 15.5
Image: S1
Specimen Label: E15.5 HE
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:4352716
Assay Type: RT-PCR
Annotation Date: 2009-08-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3276423
Stage: TS23
Assay Id: MGI:4352912
Age: embryonic day 15.5
Image: S1
Specimen Label: E15.5 KO
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:4352716
Assay Type: RT-PCR
Annotation Date: 2009-08-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3276424
Stage: TS24
Assay Id: MGI:4352912
Age: embryonic day 16.5
Image: S1
Specimen Label: E16.5 WT
Detected: true
Specimen Num: 7
GXD Expression    
Probe: MGI:4352716
Assay Type: RT-PCR
Annotation Date: 2009-08-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3276424
Stage: TS24
Assay Id: MGI:4352912
Age: embryonic day 16.5
Image: S1
Specimen Label: E16.5 HE
Detected: true
Specimen Num: 8
GXD Expression    
Probe: MGI:4352716
Assay Type: RT-PCR
Annotation Date: 2009-08-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3276424
Stage: TS24
Assay Id: MGI:4352912
Age: embryonic day 16.5
Image: S1
Specimen Label: E16.5 KO
Detected: true
Specimen Num: 9
GXD Expression    
Probe: MGI:4352716
Assay Type: RT-PCR
Annotation Date: 2009-08-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3276425
Stage: TS25
Assay Id: MGI:4352912
Age: embryonic day 17.5
Image: S1
Specimen Label: E17.5 WT
Detected: true
Specimen Num: 10
GXD Expression    
Probe: MGI:4352716
Assay Type: RT-PCR
Annotation Date: 2009-08-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3276425
Stage: TS25
Assay Id: MGI:4352912
Age: embryonic day 17.5
Image: S1
Specimen Label: E17.5 HE
Detected: true
Specimen Num: 11
GXD Expression    
Probe: MGI:4352716
Assay Type: RT-PCR
Annotation Date: 2009-08-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3276425
Stage: TS25
Assay Id: MGI:4352912
Age: embryonic day 17.5
Image: S1
Specimen Label: E17.5 KO
Detected: true
Specimen Num: 12
GXD Expression  
Probe: MGI:603066
Assay Type: RNA in situ
Annotation Date: 2011-10-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1607511
Pattern: Not Specified
Stage: TS11
Assay Id: MGI:5291694
Age: embryonic day 7.5
Image: E7.5
Specimen Label: E7.5
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:603066
Assay Type: RNA in situ
Annotation Date: 2011-10-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1607511
Pattern: Not Specified
Stage: TS11
Assay Id: MGI:5291694
Age: embryonic day 7.75
Image: E7.75
Specimen Label: E7.75
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:603066
Assay Type: RNA in situ
Annotation Date: 2011-10-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1625112
Pattern: Not Specified
Stage: TS12
Assay Id: MGI:5291694
Age: embryonic day 8.0
Image: E8.0
Specimen Label: E8.0
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:603066
Assay Type: RNA in situ
Annotation Date: 2011-10-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1625113
Pattern: Not Specified
Stage: TS13
Assay Id: MGI:5291694
Age: embryonic day 8.5
Image: E8.5
Specimen Label: E8.5
Detected: true
Specimen Num: 4
GXD Expression
Probe: MGI:603066
Assay Type: RNA in situ
Annotation Date: 2011-10-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603911
Pattern: Regionally restricted
Stage: TS11
Assay Id: MGI:5291694
Age: embryonic day 7.5
Image: E7.5
Note: Expression is present in the posterior epiblast.
Specimen Label: E7.5
Detected: true
Specimen Num: 1
GXD Expression
Probe: MGI:603066
Assay Type: RNA in situ
Annotation Date: 2011-10-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603911
Pattern: Regionally restricted
Stage: TS11
Assay Id: MGI:5291694
Age: embryonic day 7.75
Image: E7.75
Note: Expression is present in the posterior epiblast.
Specimen Label: E7.75
Detected: true
Specimen Num: 2
GXD Expression
Probe: MGI:603066
Assay Type: RNA in situ
Annotation Date: 2011-10-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1619112
Pattern: Regionally restricted
Stage: TS12
Assay Id: MGI:5291694
Age: embryonic day 8.0
Image: E8.0
Note: Expression is present in the posterior notochord.
Specimen Label: E8.0
Detected: true
Specimen Num: 3
GXD Expression
Probe: MGI:603066
Assay Type: RNA in situ
Annotation Date: 2011-10-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1619113
Pattern: Regionally restricted
Stage: TS13
Assay Id: MGI:5291694
Age: embryonic day 8.5
Image: E8.5
Note: Expression is present in the posterior notochord.
Specimen Label: E8.5
Detected: true
Specimen Num: 4
GXD Expression  
Probe: MGI:6188506
Assay Type: RNA in situ
Annotation Date: 2018-07-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3784028
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:6188597
Age: postnatal adult
Note: Expression is in Paneth cells.
Specimen Label: 7G
Detected: true
Specimen Num: 1
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Publication
First Author: Huttner KM
Year: 1994
Journal: Genomics
Title: A family of defensin-like genes codes for diverse cysteine-rich peptides in mouse Paneth cells.
Volume: 24
Issue: 1
Pages: 99-109
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Publication
First Author: Ouellette AJ
Year: 1990
Journal: J Biol Chem
Title: A novel mouse gene family coding for cationic, cysteine-rich peptides. Regulation in small intestine and cells of myeloid origin.
Volume: 265
Issue: 17
Pages: 9831-7
Publication
First Author: Garabedian EM
Year: 1998
Journal: Proc Natl Acad Sci U S A
Title: A transgenic mouse model of metastatic prostate cancer originating from neuroendocrine cells.
Volume: 95
Issue: 26
Pages: 15382-7
Publication
First Author: Bry L
Year: 1994
Journal: Proc Natl Acad Sci U S A
Title: Paneth cell differentiation in the developing intestine of normal and transgenic mice.
Volume: 91
Issue: 22
Pages: 10335-9
Publication
First Author: Wilson CL
Year: 1995
Journal: Mol Biol Cell
Title: The metalloproteinase matrilysin is preferentially expressed by epithelial cells in a tissue-restricted pattern in the mouse.
Volume: 6
Issue: 7
Pages: 851-69
Publication
First Author: Hornef MW
Year: 2004
Journal: Nat Immunol
Title: Increased diversity of intestinal antimicrobial peptides by covalent dimer formation.
Volume: 5
Issue: 8
Pages: 836-43
Publication
First Author: Shanahan MT
Year: 2010
Journal: J Biol Chem
Title: Elevated expression of Paneth cell CRS4C in ileitis-prone SAMP1/YitFc mice: regional distribution, subcellular localization, and mechanism of action.
Volume: 285
Issue: 10
Pages: 7493-504
Publication
First Author: Wilson SS
Year: 2017
Journal: PLoS Pathog
Title: Alpha-defensin-dependent enhancement of enteric viral infection.
Volume: 13
Issue: 6
Pages: e1006446
Publication
First Author: Lin MY
Year: 1992
Journal: Genomics
Title: The defensin-related murine CRS1C gene: expression in Paneth cells and linkage to Defcr, the cryptdin locus.
Volume: 14
Issue: 2
Pages: 363-8
Publication
First Author: Darmoul D
Year: 1996
Journal: Am J Physiol
Title: Positional specificity of defensin gene expression reveals Paneth cell heterogeneity in mouse small intestine.
Volume: 271
Issue: 1 Pt 1
Pages: G68-74
Publication
First Author: Morrison GM
Year: 1998
Journal: Mamm Genome
Title: Mouse beta defensin-1 is a functional homolog of human beta defensin-1.
Volume: 9
Issue: 6
Pages: 453-7
Publication
First Author: Weeks CS
Year: 2006
Journal: J Biol Chem
Title: Matrix metalloproteinase-7 activation of mouse paneth cell pro-alpha-defensins: SER43 down arrow ILE44 proteolysis enables membrane-disruptive activity.
Volume: 281
Issue: 39
Pages: 28932-42
Publication
First Author: Le Bacquer O
Year: 2007
Journal: J Clin Invest
Title: Elevated sensitivity to diet-induced obesity and insulin resistance in mice lacking 4E-BP1 and 4E-BP2.
Volume: 117
Issue: 2
Pages: 387-96
Publication
First Author: Ouellette AJ
Year: 1999
Journal: Infect Immun
Title: Peptide localization and gene structure of cryptdin 4, a differentially expressed mouse paneth cell alpha-defensin.
Volume: 67
Issue: 12
Pages: 6643-51
Publication
First Author: Economopoulou M
Year: 2005
Journal: Blood
Title: Inhibition of pathologic retinal neovascularization by alpha-defensins.
Volume: 106
Issue: 12
Pages: 3831-8
Publication
First Author: Patil A
Year: 2004
Journal: Physiol Genomics
Title: Rapid evolution and diversification of mammalian alpha-defensins as revealed by comparative analysis of rodent and primate genes.
Volume: 20
Issue: 1
Pages: 1-11
Publication
First Author: White RA
Year: 1990
Journal: Proc Natl Acad Sci U S A
Title: Ankyrin and the hemolytic anemia mutation, nb, map to mouse chromosome 8: presence of the nb allele is associated with a truncated erythrocyte ankyrin.
Volume: 87
Issue: 8
Pages: 3117-21