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Search results 1 to 100 out of 133 for Depdc5

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Type Details Score
Gene
9681 | DEPDC5
Type: gene
Organism: human
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Gene
477546 | DEPDC5
Type: gene
Organism: dog, domestic
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Gene
521542 | DEPDC5
Type: gene
Organism: cattle
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Gene
416956 | DEPDC5
Type: gene
Organism: chicken
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Gene
562995 | depdc5
Type: gene
Organism: zebrafish
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Gene
718522 | DEPDC5
Type: gene
Organism: macaque, rhesus
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Gene
100498286 | depdc5
Type: gene
Organism: frog, western clawed
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Gene
107970229 | DEPDC5
Type: gene
Organism: chimpanzee
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Gene
305464 | Depdc5
Type: gene
Organism: rat
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Protein Coding Gene
MGI:2141101 | Depdc5
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
23542697 | J:197613
First Author: Dibbens LM
Year: 2013
Journal: Nat Genet
Title: Mutations in DEPDC5 cause familial focal epilepsy with variable foci.
Volume: 45
Issue: 5
Pages: 546-51
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Publication
28974734 | J:256299
First Author: Hughes J
Year: 2017
Journal: Sci Rep
Title: Knockout of the epilepsy gene Depdc5 in mice causes severe embryonic dysmorphology with hyperactivity of mTORC1 signalling.
Volume: 7
Issue: 1
Pages: 12618
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Publication
34267188 | J:310083
First Author: Xu L
Year: 2021
Journal: Cell Death Dis
Title: Depdc5 deficiency exacerbates alcohol-induced hepatic steatosis via suppression of PPARĪ± pathway.
Volume: 12
Issue: 7
Pages: 710
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Publication
32113911 | J:297604
 
First Author: De Fusco A
Year: 2020
Journal: Neurobiol Dis
Title: Acute knockdown of Depdc5 leads to synaptic defects in mTOR-related epileptogenesis.
Volume: 139
Pages: 104822
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Publication
31174205 | J:280714
First Author: Yuskaitis CJ
Year: 2019
Journal: Hum Mol Genet
Title: Chronic mTORC1 inhibition rescues behavioral and biochemical deficits resulting from neuronal Depdc5 loss in mice.
Volume: 28
Issue: 17
Pages: 2952-2964
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Publication
34243067 | J:311126
 
First Author: Zhang J
Year: 2021
Journal: Biochem Biophys Res Commun
Title: Adipocyte-specific deletion of Depdc5 exacerbates insulin resistance and adipose tissue inflammation in mice.
Volume: 569
Pages: 118-124
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Publication
32280987 | J:291037
First Author: Klofas LK
Year: 2020
Journal: Hum Mol Genet
Title: Prevention of premature death and seizures in a Depdc5 mouse epilepsy model through inhibition of mTORC1.
Volume: 29
Issue: 8
Pages: 1365-1377
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Publication
29274432 | J:260943
 
First Author: Yuskaitis CJ
Year: 2018
Journal: Neurobiol Dis
Title: A mouse model of DEPDC5-related epilepsy: Neuronal loss of Depdc5 causes dysplastic and ectopic neurons, increased mTOR signaling, and seizure susceptibility.
Volume: 111
Pages: 91-101
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Publication
34562654 | J:312868
 
First Author: Xu L
Year: 2021
Journal: Biochem Biophys Res Commun
Title: Persistent mTORC1 activation via Depdc5 deletion results in spontaneous hepatocellular carcinoma but does not exacerbate carcinogen- and high-fat diet-induced hepatic carcinogenesis in mice.
Volume: 578
Pages: 142-149
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Publication
34964695 | J:339463
First Author: Cho CS
Year: 2022
Journal: Autophagy
Title: Simultaneous loss of TSC1 and DEPDC5 in skeletal and cardiac muscles produces early-onset myopathy and cardiac dysfunction associated with oxidative damage and SQSTM1/p62 accumulation.
Volume: 18
Issue: 10
Pages: 2303-2322
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Gene
108707109 | LOC108707109
Type: gene
Organism: frog, African clawed
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Gene
108716023 | LOC108716023
Type: gene
Organism: frog, African clawed
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Publication
35580549 | J:339090
First Author: Yang T
Year: 2022
Journal: Dev Neurosci
Title: Perineuronal Nets Degradation and Parvalbumin Interneuron Loss in a Mouse Model of DEPDC5-Related Epilepsy.
Volume: 44
Issue: 6
Pages: 671-677
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Publication
30635399 | J:275966
First Author: Graber TG
Year: 2019
Journal: J Biol Chem
Title: Skeletal muscle-specific knockout of DEP domain containing 5 protein increases mTORC1 signaling, muscle cell hypertrophy, and mitochondrial respiration.
Volume: 294
Issue: 11
Pages: 4091-4102
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Publication
37606181 | J:340876
     
First Author: Kao HY
Year: 2023
Journal: Ann Neurol
Title: Sudden Unexpected Death in Epilepsy and Respiratory Defects in a Mouse Model of DEPDC5-Related Epilepsy.
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Publication
36044864 | J:328313
First Author: Yuskaitis CJ
Year: 2022
Journal: Cell Rep
Title: DEPDC5-dependent mTORC1 signaling mechanisms are critical for the anti-seizure effects of acute fasting.
Volume: 40
Issue: 9
Pages: 111278
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Publication
31754457 | J:339464
 
First Author: Cho CS
Year: 2019
Journal: Cell Discov
Title: Concurrent activation of growth factor and nutrient arms of mTORC1 induces oxidative liver injury.
Volume: 5
Pages: 60
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Protein Coding Gene
MGP_CAROLIEiJ_G0027107 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0029439 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0029406 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0029355 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0029416 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0029138 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_2141101 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0029870 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0028547 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0029106 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0029254 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0029213 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0029339 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0029243 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0029904 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0028272 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0028628 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0016891 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0028103 | -
Type: protein_coding_gene
Organism: Mus spretus
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GXD Expression
GXD Expression
 
Probe: MGI:4845290
Assay Type: RNA in situ
Annotation Date: 2010-12-22
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1611817
Pattern: Not Specified
Stage: TS17
Assay Id: MGI:4848916
Age: embryonic day 10.5
Note: Staining is present in the mandibular arch.
Specimen Label: Table S4 - E10.5
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1737328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692391
Age: postnatal adult
Image: MRC Harwell_1305273
Note: kidney
Specimen Label: MRC Harwell_1305273
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1666528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692391
Age: postnatal adult
Image: MRC Harwell_1305274
Specimen Label: MRC Harwell_1305274
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:4845290
Assay Type: RNA in situ
Annotation Date: 2010-12-22
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1640519
Pattern: Regionally restricted
Stage: TS19
Assay Id: MGI:4848916
Age: embryonic day 11.5
Note: Staining is present in the antero-distal and posterior-distal regions of the limb.
Specimen Label: Table S4 - E11.5
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:4845290
Assay Type: RNA in situ
Annotation Date: 2010-12-22
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1738219
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:4848916
Age: embryonic day 11.5
Note: Staining is present in the external genitalia.
Specimen Label: Table S4 - E11.5
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:4845290
Assay Type: RNA in situ
Annotation Date: 2010-12-22
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:3270519
Pattern: Regionally restricted
Stage: TS19
Assay Id: MGI:4848916
Age: embryonic day 11.5
Note: Staining is present in the progress zone and middle limb.
Specimen Label: Table S4 - E11.5
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:4845290
Assay Type: RNA in situ
Annotation Date: 2010-12-22
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1627217
Pattern: Not Specified
Stage: TS17
Assay Id: MGI:4848916
Age: embryonic day 10.5
Note: Staining is present in the hyoid arch.
Specimen Label: Table S4 - E10.5
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692391
Age: postnatal adult
Image: MRC Harwell_1305275
Specimen Label: MRC Harwell_1305275
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1928728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692391
Age: postnatal adult
Image: MRC Harwell_1305276
Specimen Label: MRC Harwell_1305276
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
 
Probe: MGI:4845290
Assay Type: RNA in situ
Annotation Date: 2010-12-22
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1638817
Pattern: Not Specified
Stage: TS17
Assay Id: MGI:4848916
Age: embryonic day 10.5
Note: Staining is present in the maxillary process.
Specimen Label: Table S4 - E10.5
Detected: true
Specimen Num: 1
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Publication
34965576 | J:326754
First Author: Ishida S
Year: 2022
Journal: Hum Mol Genet
Title: Dorsal telencephalon-specific Nprl2- and Nprl3-knockout mice: novel mouse models for GATORopathy.
Volume: 31
Issue: 9
Pages: 1519-1530
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Publication
34795452 | J:345359
First Author: Long L
Year: 2021
Journal: Nature
Title: CRISPR screens unveil signal hubs for nutrient licensing of T cell immunity.
Volume: 600
Issue: 7888
Pages: 308-313
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Publication
36528027 | J:332370
First Author: Jiang C
Year: 2023
Journal: Mol Cell
Title: Ring domains are essential for GATOR2-dependent mTORC1 activation.
Volume: 83
Issue: 1
Pages: 74-89.e9
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Publication
37380769 | J:338195
First Author: Zhang X
Year: 2023
Journal: Nature
Title: Reprogramming tumour-associated macrophages to outcompete cancer cells.
Volume: 619
Issue: 7970
Pages: 616-623
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Protein
P61460
Organism: Mus musculus/domesticus
Length: 1591  
Fragment?: false
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Protein
F6TK47
Organism: Mus musculus/domesticus
Length: 976  
Fragment?: true
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Protein
Q6GQV2
Organism: Mus musculus/domesticus
Length: 1530  
Fragment?: false
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Publication
22802532 | J:185949
First Author: Licatalosi DD
Year: 2012
Journal: Genes Dev
Title: Ptbp2 represses adult-specific splicing to regulate the generation of neuronal precursors in the embryonic brain.
Volume: 26
Issue: 14
Pages: 1626-42
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Publication
- | J:104190
     
First Author: The Australian Phenomics Facility at The Australian National University
Year: 2006
Journal: MGI Direct Data Submission
Title: Heritable mouse mutants from the ENU mutagenesis program at the Australian Phenomics Facility at The Australian National University
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Publication
20059953 | J:156017
First Author: Yokoyama S
Year: 2009
Journal: Dev Cell
Title: A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58.
Volume: 17
Issue: 6
Pages: 836-48
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Publication
27626380 | J:236599
First Author: Dickinson ME
Year: 2016
Journal: Nature
Title: High-throughput discovery of novel developmental phenotypes.
Volume: 537
Issue: 7621
Pages: 508-514
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Publication
17967808 | J:152068
First Author: Friedel RH
Year: 2007
Journal: Brief Funct Genomic Proteomic
Title: EUCOMM--the European conditional mouse mutagenesis program.
Volume: 6
Issue: 3
Pages: 180-5
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Publication
24194600 | J:228563
First Author: Koscielny G
Year: 2014
Journal: Nucleic Acids Res
Title: The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data.
Volume: 42
Issue: Database issue
Pages: D802-9
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Publication
- | J:80155
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations for FANTOM2 data
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Publication
12520002 | J:91812
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
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Publication
- | J:204739
     
First Author: International Knockout Mouse Consortium
Year: 2014
Journal: Database Download
Title: MGI download of modified allele data from IKMC and creation of new knockout alleles
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Publication
- | J:204812
     
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
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Publication
- | J:157065
     
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
- | J:72247
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
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Publication
18799693 | J:142754
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
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Publication
- | J:211773
     
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
- | J:164563
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

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