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Search results 1 to 100 out of 165 for Deptor

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Hits by Pathway

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Hits by Strain

Type Details Score
Gene
64798 | DEPTOR
Type: gene
Organism: human
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Gene
100493830 | deptor
Type: gene
Organism: frog, western clawed
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Gene
482028 | DEPTOR
Type: gene
Organism: dog, domestic
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Gene
314979 | Deptor
Type: gene
Organism: rat
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Gene
464357 | DEPTOR
Type: gene
Organism: chimpanzee
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Gene
617606 | DEPTOR
Type: gene
Organism: cattle
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Gene
420357 | DEPTOR
Type: gene
Organism: chicken
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Gene
768177 | deptor
Type: gene
Organism: zebrafish
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Gene
702649 | DEPTOR
Type: gene
Organism: macaque, rhesus
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Protein Domain
IPR037589 | DEPTOR
Type: Family
Description: This entry represents the DEP domain-containing mTOR-interacting protein (DEPTOR) which is a negative regulator of mTORC1 and mTORC2 signaling pathways, inhibiting the kinase activity of both complexes [].
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Protein Coding Gene
MGI:2146322 | Deptor
Type: protein_coding_gene
Organism: mouse, laboratory
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Gene
121676927 | DEPTOR-AS1
Type: gene
Organism: human
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Publication
22883231 | J:187378
First Author: Laplante M
Year: 2012
Journal: Cell Metab
Title: DEPTOR cell-autonomously promotes adipogenesis, and its expression is associated with obesity.
Volume: 16
Issue: 2
Pages: 202-12
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Publication
29614494 | J:339239
First Author: Ding Y
Year: 2018
Journal: Cell Physiol Biochem
Title: DEPTOR Deficiency-Mediated mTORc1 Hyperactivation in Vascular Endothelial Cells Promotes Angiogenesis.
Volume: 46
Issue: 2
Pages: 520-531
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Publication
28462079 | J:275931
First Author: Caron A
Year: 2017
Journal: Mol Metab
Title: Loss of hepatic DEPTOR alters the metabolic transition to fasting.
Volume: 6
Issue: 5
Pages: 447-458
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Publication
29969188 | J:306489
First Author: Wedel J
Year: 2019
Journal: Am J Transplant
Title: DEPTOR modulates activation responses in CD4+ T cells and enhances immunoregulation following transplantation.
Volume: 19
Issue: 1
Pages: 77-88
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Publication
34320372 | J:309427
 
First Author: Gong L
Year: 2021
Journal: Cancer Lett
Title: DEPTOR inhibits lung tumorigenesis by inactivating the EGFR-mTOR signals.
Volume: 519
Pages: 263-276
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Publication
35609371 | J:328674
 
First Author: Ouyang Z
Year: 2022
Journal: Biomed Pharmacother
Title: DEPTOR exacerbates bone-fat imbalance in osteoporosis by transcriptionally modulating BMSC differentiation.
Volume: 151
Pages: 113164
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Publication
25258312 | J:218804
First Author: Agrawal P
Year: 2014
Journal: J Biol Chem
Title: DEPTOR is a stemness factor that regulates pluripotency of embryonic stem cells.
Volume: 289
Issue: 46
Pages: 31818-26
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Publication
32916025 | J:339240
First Author: Li K
Year: 2021
Journal: J Bone Miner Res
Title: DEPTOR Prevents Osteoarthritis Development Via Interplay With TRC8 to Reduce Endoplasmic Reticulum Stress in Chondrocytes.
Volume: 36
Issue: 2
Pages: 400-411
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Publication
19446321 | -
First Author: Peterson TR
Year: 2009
Journal: Cell
Title: DEPTOR is an mTOR inhibitor frequently overexpressed in multiple myeloma cells and required for their survival.
Volume: 137
Issue: 5
Pages: 873-86
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Publication
29670094 | J:265006
First Author: Wang C
Year: 2018
Journal: Cell Death Dis
Title: Loss of DEPTOR in renal tubules protects against cisplatin-induced acute kidney injury.
Volume: 9
Issue: 5
Pages: 441
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Publication
26795633 | J:236071
 
First Author: González-Terán B
Year: 2016
Journal: Nat Commun
Title: p38γ and δ promote heart hypertrophy by targeting the mTOR-inhibitory protein DEPTOR for degradation.
Volume: 7
Pages: 10477
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Publication
31685947 | J:297884
First Author: Chen X
Year: 2020
Journal: Oncogene
Title: DEPTOR is an in vivo tumor suppressor that inhibits prostate tumorigenesis via the inactivation of mTORC1/2 signals.
Volume: 39
Issue: 7
Pages: 1557-1571
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Publication
36535626 | J:336790
 
First Author: Colas C
Year: 2023
Journal: Mol Metab
Title: DEPTOR loss impairs brown adipocyte development in vitro but has limited impacts in mice.
Volume: 67
Pages: 101660
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Publication
27097662 | J:306785
First Author: Caron A
Year: 2016
Journal: Am J Physiol Regul Integr Comp Physiol
Title: DEPTOR in POMC neurons affects liver metabolism but is dispensable for the regulation of energy balance.
Volume: 310
Issue: 11
Pages: R1322-31
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Publication
29666061 | J:262591
First Author: Wang Q
Year: 2018
Journal: Cancer Res
Title: Deptor Is a Novel Target of Wnt/β-Catenin/c-Myc and Contributes to Colorectal Cancer Cell Growth.
Volume: 78
Issue: 12
Pages: 3163-3175
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Protein
Q570Y9
Organism: Mus musculus/domesticus
Length: 409  
Fragment?: false
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Protein
B2ZRS5
Organism: Mus musculus/domesticus
Length: 401  
Fragment?: false
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Protein
A0A2I3BRE1
Organism: Mus musculus/domesticus
Length: 100  
Fragment?: false
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Protein
B2ZRS6
Organism: Mus musculus/domesticus
Length: 401  
Fragment?: false
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Protein
B2ZRS7
Organism: Mus musculus/domesticus
Length: 397  
Fragment?: false
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Protein
B2ZRS8
Organism: Mus musculus/domesticus
Length: 396  
Fragment?: false
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Protein
B2ZRS3
Organism: Mus musculus/domesticus
Length: 409  
Fragment?: false
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Publication
23563706 | J:198532
First Author: Meng ZX
Year: 2013
Journal: Nat Med
Title: Baf60c drives glycolytic metabolism in the muscle and improves systemic glucose homeostasis through Deptor-mediated Akt activation.
Volume: 19
Issue: 5
Pages: 640-5
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Publication
32722876 | J:305500
First Author: Feng GJ
Year: 2020
Journal: J Cell Physiol
Title: Helicobacter pylori promote inflammation and host defense through the cagA-dependent activation of mTORC1.
Volume: 235
Issue: 12
Pages: 10094-10108
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Publication
32510855 | J:328677
First Author: Li Y
Year: 2020
Journal: J Cell Mol Med
Title: miRNA-182/Deptor/mTOR axis regulates autophagy to reduce intestinal ischaemia/reperfusion injury.
Volume: 24
Issue: 14
Pages: 7873-7883
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Publication
27144580 | J:320546
 
First Author: Tian Y
Year: 2016
Journal: Nutrients
Title: Chemopreventive Effect of Dietary Glutamineon Colitis-Associated Colorectal Cancer Is Associated with Modulation of the DEPTOR/mTOR Signaling Pathway.
Volume: 8
Issue: 5
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Publication
29457836 | J:301785
First Author: Chen H
Year: 2018
Journal: Hepatology
Title: DEP domain-containing mTOR-interacting protein suppresses lipogenesis and ameliorates hepatic steatosis and acute-on-chronic liver injury in alcoholic liver disease.
Volume: 68
Issue: 2
Pages: 496-514
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Publication
36548081 | J:333347
 
First Author: Zhang S
Year: 2023
Journal: J Clin Invest
Title: The UBE2C/CDH1/DEPTOR axis is an oncogene and tumor suppressor cascade in lung cancer cells.
Volume: 133
Issue: 4
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Protein Coding Gene
MGP_CAROLIEiJ_G0019797 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0021854 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0021814 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0021795 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0021821 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0021595 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_2146322 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0022260 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0021112 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0021564 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0021688 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0021666 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0021758 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0021690 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0022283 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0020857 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0021167 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0019807 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0020694 | -
Type: protein_coding_gene
Organism: Mus spretus
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GXD Expression
GXD Expression
   
Probe: MGI:7596429
Assay Type: Western blot
Annotation Date: 2024-02-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672826
Stage: TS26
Assay Id: MGI:7596446
Age: embryonic day 18.5
Image: 7
Specimen Label: 1
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:7596429
Assay Type: Western blot
Annotation Date: 2024-02-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672826
Stage: TS26
Assay Id: MGI:7596446
Age: embryonic day 18.5
Image: 7
Specimen Label: 2
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:7596429
Assay Type: Western blot
Annotation Date: 2024-02-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672826
Stage: TS26
Assay Id: MGI:7596446
Age: embryonic day 18.5
Image: 7
Specimen Label: 3
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:7596429
Assay Type: Western blot
Annotation Date: 2024-02-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672826
Stage: TS26
Assay Id: MGI:7596446
Age: embryonic day 18.5
Image: 7
Specimen Label: 4
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:7596429
Assay Type: Western blot
Annotation Date: 2024-02-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672826
Stage: TS26
Assay Id: MGI:7596446
Age: embryonic day 18.5
Image: 7
Specimen Label: 5
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
   
Probe: MGI:7596429
Assay Type: Western blot
Annotation Date: 2024-02-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672826
Stage: TS26
Assay Id: MGI:7596446
Age: embryonic day 18.5
Image: 7
Specimen Label: 6
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
   
Probe: MGI:7596429
Assay Type: Western blot
Annotation Date: 2024-02-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672826
Stage: TS26
Assay Id: MGI:7596446
Age: embryonic day 18.5
Image: 7
Specimen Label: 7
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
   
Probe: MGI:7596429
Assay Type: Western blot
Annotation Date: 2024-02-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672826
Stage: TS26
Assay Id: MGI:7596446
Age: embryonic day 18.5
Image: 7
Specimen Label: 8
Detected: true
Specimen Num: 8
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GXD Expression
GXD Expression
   
Probe: MGI:7596429
Assay Type: Western blot
Annotation Date: 2024-02-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672826
Stage: TS26
Assay Id: MGI:7596446
Age: embryonic day 18.5
Image: 7
Specimen Label: 9
Detected: true
Specimen Num: 9
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GXD Expression
GXD Expression
     
Probe: MGI:6171120
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689419
Stage: TS19
Assay Id: MGI:6190113
Age: embryonic day 11.5
Specimen Label: Table S2 - E11.5 - Depdc6
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:6171120
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689421
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:6190113
Age: embryonic day 13.5
Specimen Label: Table S2 - E13.5 - Depdc6
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:6171120
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689424
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:6190113
Age: embryonic day 15.5
Specimen Label: Table S2 - E15.5 - Depdc6
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:6171120
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689426
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:6190113
Age: embryonic day 18.5
Specimen Label: Table S2 - E18.5 - Depdc6
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:6171120
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6190113
Age: postnatal day 4
Specimen Label: Table S2 - P4 - Depdc6
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
   
Probe: MGI:6171120
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6190113
Age: postnatal day 14
Specimen Label: Table S2 - P14 - Depdc6
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
   
Probe: MGI:6171120
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6190113
Age: postnatal day 28
Specimen Label: Table S2 - P28 - Depdc6
Detected: true
Specimen Num: 7
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Publication
11285235 | J:66178
First Author: Malik TH
Year: 2001
Journal: EMBO J
Title: Transcriptional repression and developmental functions of the atypical vertebrate GATA protein TRPS1.
Volume: 20
Issue: 7
Pages: 1715-25
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Publication
34793600 | J:317363
First Author: Ruiz-Serrano A
Year: 2021
Journal: FASEB J
Title: OTUB1 regulates lung development, adult lung tissue homeostasis, and respiratory control.
Volume: 35
Issue: 12
Pages: e22039
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Publication
32553114 | J:292114
   
First Author: Pereira M
Year: 2020
Journal: Elife
Title: A trans-eQTL network regulates osteoclast multinucleation and bone mass.
Volume: 9
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Publication
26299309 | J:224980
 
First Author: Lee KY
Year: 2015
Journal: Nat Commun
Title: Tbx15 controls skeletal muscle fibre-type determination and muscle metabolism.
Volume: 6
Pages: 8054
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Publication
33473114 | J:301232
First Author: Butterfield NC
Year: 2021
Journal: Nat Commun
Title: Accelerating functional gene discovery in osteoarthritis.
Volume: 12
Issue: 1
Pages: 467
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Publication
27597886 | J:270627
First Author: Sakakibara I
Year: 2016
Journal: Skelet Muscle
Title: Six1 homeoprotein drives myofiber type IIA specialization in soleus muscle.
Volume: 6
Issue: 1
Pages: 30
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
10512203 | J:93290
First Author: Araki K
Year: 1999
Journal: Cell Mol Biol (Noisy-le-grand)
Title: Exchangeable gene trap using the Cre/mutated lox system.
Volume: 45
Issue: 5
Pages: 737-50
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Publication
15840001 | J:110088
First Author: Taniwaki T
Year: 2005
Journal: Dev Growth Differ
Title: Characterization of an exchangeable gene trap using pU-17 carrying a stop codon-beta geo cassette.
Volume: 47
Issue: 3
Pages: 163-72
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Publication
- | J:24194
     
First Author: The Jackson Laboratory Backcross DNA Panel Mapping Resource
Year: 1999
Journal: Database Release
Title: JAX BSS Panel Mapping Data
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Publication
10725249 | J:60984
First Author: Ko MS
Year: 2000
Journal: Development
Title: Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development.
Volume: 127
Issue: 8
Pages: 1737-49
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Publication
- | J:80001
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: FANTOM2 Data Curation in Mouse Genome Informatics
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Publication
17967808 | J:152068
First Author: Friedel RH
Year: 2007
Journal: Brief Funct Genomic Proteomic
Title: EUCOMM--the European conditional mouse mutagenesis program.
Volume: 6
Issue: 3
Pages: 180-5
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Publication
24952961 | J:215487
First Author: Thompson CL
Year: 2014
Journal: Neuron
Title: A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain.
Volume: 83
Issue: 2
Pages: 309-323
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Publication
12520002 | J:91812
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
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Publication
- | J:204739
     
First Author: International Knockout Mouse Consortium
Year: 2014
Journal: Database Download
Title: MGI download of modified allele data from IKMC and creation of new knockout alleles
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Publication
- | J:204812
     
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
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Publication
- | J:155845
     
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
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Publication
18799693 | J:142754
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
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Publication
- | J:72247
       
First Author: DDB, FB, MGI, GOA, ZFIN curators
Year: 2001
Title: Gene Ontology annotation through association of InterPro records with GO terms
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Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
38355793 | J:345621
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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