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Search results 1 to 100 out of 328 for Dgat1

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Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: chimpanzee
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: macaque, rhesus
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Publication
First Author: Liu L
Year: 2009
Journal: J Biol Chem
Title: DGAT1 expression increases heart triglyceride content but ameliorates lipotoxicity.
Volume: 284
Issue: 52
Pages: 36312-23
Publication
First Author: Shih MY
Year: 2009
Journal: J Biol Chem
Title: Retinol Esterification by DGAT1 Is Essential for Retinoid Homeostasis in Murine Skin.
Volume: 284
Issue: 7
Pages: 4292-9
Publication
First Author: Cases S
Year: 2004
Journal: Development
Title: Development of the mammary gland requires DGAT1 expression in stromal and epithelial tissues.
Volume: 131
Issue: 13
Pages: 3047-55
Publication
First Author: Chitraju C
Year: 2017
Journal: Cell Metab
Title: Triglyceride Synthesis by DGAT1 Protects Adipocytes from Lipid-Induced ER Stress during Lipolysis.
Volume: 26
Issue: 2
Pages: 407-418.e3
Publication
First Author: Buhman KK
Year: 2002
Journal: J Biol Chem
Title: DGAT1 is not essential for intestinal triacylglycerol absorption or chylomicron synthesis.
Volume: 277
Issue: 28
Pages: 25474-9
Publication
First Author: Mo X
Year: 2015
Journal: PLoS One
Title: F3MB(PANDER) decreases mice hepatic triglyceride and is associated with decreased DGAT1 expression.
Volume: 10
Issue: 2
Pages: e0117156
Publication
First Author: Graham KL
Year: 2019
Journal: Proc Natl Acad Sci U S A
Title: DGAT1 inhibits retinol-dependent regulatory T cell formation and mediates autoimmune encephalomyelitis.
Volume: 116
Issue: 8
Pages: 3126-3135
Publication
First Author: Liu L
Year: 2007
Journal: J Clin Invest
Title: Upregulation of myocellular DGAT1 augments triglyceride synthesis in skeletal muscle and protects against fat-induced insulin resistance.
Volume: 117
Issue: 6
Pages: 1679-89
Publication
First Author: Liu L
Year: 2011
Journal: J Lipid Res
Title: DGAT1 deficiency decreases PPAR expression and does not lead to lipotoxicity in cardiac and skeletal muscle.
Volume: 52
Issue: 4
Pages: 732-44
Publication
First Author: Maciejewski BS
Year: 2013
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Pharmacological inhibition to examine the role of DGAT1 in dietary lipid absorption in rodents and humans.
Volume: 304
Issue: 11
Pages: G958-69
Publication
First Author: Siloto RM
Year: 2008
Journal: Biochem Biophys Res Commun
Title: An N-terminal fragment of mouse DGAT1 binds different acyl-CoAs with varying affinity.
Volume: 373
Issue: 3
Pages: 350-4
Publication
First Author: Sachdev V
Year: 2016
Journal: Biochim Biophys Acta
Title: Novel role of a triglyceride-synthesizing enzyme: DGAT1 at the crossroad between triglyceride and cholesterol metabolism.
Volume: 1861
Issue: 9 Pt A
Pages: 1132-1141
Publication  
First Author: de la Rosa Rodriguez MA
Year: 2021
Journal: Mol Metab
Title: Hypoxia-inducible lipid droplet-associated induces DGAT1 and promotes lipid storage in hepatocytes.
Volume: 47
Pages: 101168
Publication
First Author: Tuohetahuntila M
Year: 2016
Journal: J Lipid Res
Title: ATGL and DGAT1 are involved in the turnover of newly synthesized triacylglycerols in hepatic stellate cells.
Volume: 57
Issue: 7
Pages: 1162-74
Publication
First Author: Okawa M
Year: 2009
Journal: Biochem Biophys Res Commun
Title: Role of MGAT2 and DGAT1 in the release of gut peptides after triglyceride ingestion.
Volume: 390
Issue: 3
Pages: 377-81
Publication
First Author: Streeper RS
Year: 2006
Journal: Am J Physiol Endocrinol Metab
Title: Effects of DGAT1 deficiency on energy and glucose metabolism are independent of adiponectin.
Volume: 291
Issue: 2
Pages: E388-94
Publication
First Author: Ables GP
Year: 2012
Journal: J Lipid Res
Title: Intestinal DGAT1 deficiency reduces postprandial triglyceride and retinyl ester excursions by inhibiting chylomicron secretion and delaying gastric emptying.
Volume: 53
Issue: 11
Pages: 2364-79
Publication
First Author: Chen N
Year: 2005
Journal: Diabetes
Title: Whole-body insulin resistance in the absence of obesity in FVB mice with overexpression of Dgat1 in adipose tissue.
Volume: 54
Issue: 12
Pages: 3379-86
Publication
First Author: Irshad Z
Year: 2019
Journal: J Lipid Res
Title: Hepatic VLDL secretion: DGAT1 determines particle size but not particle number, which can be supported entirely by DGAT2.
Volume: 60
Issue: 1
Pages: 111-120
Publication
First Author: Hung YH
Year: 2019
Journal: Biochim Biophys Acta Mol Cell Biol Lipids
Title: DGAT1 deficiency disrupts lysosome function in enterocytes during dietary fat absorption.
Volume: 1864
Issue: 4
Pages: 587-595
Publication
First Author: Hung YH
Year: 2017
Journal: Biochim Biophys Acta
Title: Dgat1 and Dgat2 regulate enterocyte triacylglycerol distribution and alter proteins associated with cytoplasmic lipid droplets in response to dietary fat.
Volume: 1862
Issue: 6
Pages: 600-614
Publication
First Author: Grisart B
Year: 2002
Journal: Genome Res
Title: Positional candidate cloning of a QTL in dairy cattle: identification of a missense mutation in the bovine DGAT1 gene with major effect on milk yield and composition.
Volume: 12
Issue: 2
Pages: 222-31
Publication
First Author: Meegalla RL
Year: 2002
Journal: Biochem Biophys Res Commun
Title: Concerted elevation of acyl-coenzyme A:diacylglycerol acyltransferase (DGAT) activity through independent stimulation of mRNA expression of DGAT1 and DGAT2 by carbohydrate and insulin.
Volume: 298
Issue: 3
Pages: 317-23
Publication
First Author: Koliwad SK
Year: 2010
Journal: J Clin Invest
Title: DGAT1-dependent triacylglycerol storage by macrophages protects mice from diet-induced insulin resistance and inflammation.
Volume: 120
Issue: 3
Pages: 756-67
Publication
First Author: Streeper RS
Year: 2012
Journal: Aging (Albany NY)
Title: Deficiency of the lipid synthesis enzyme, DGAT1, extends longevity in mice.
Volume: 4
Issue: 1
Pages: 13-27
Publication
First Author: Lee B
Year: 2010
Journal: J Lipid Res
Title: Intestine-specific expression of acyl CoA:diacylglycerol acyltransferase 1 reverses resistance to diet-induced hepatic steatosis and obesity in Dgat1-/- mice.
Volume: 51
Issue: 7
Pages: 1770-80
Publication
First Author: Lin HV
Year: 2013
Journal: PLoS One
Title: Diacylglycerol acyltransferase-1 (DGAT1) inhibition perturbs postprandial gut hormone release.
Volume: 8
Issue: 1
Pages: e54480
Publication
First Author: Chitraju C
Year: 2020
Journal: Cell Rep
Title: Lipid Droplets in Brown Adipose Tissue Are Dispensable for Cold-Induced Thermogenesis.
Volume: 33
Issue: 5
Pages: 108348
Publication
First Author: Yen CL
Year: 2008
Journal: J Lipid Res
Title: Thematic review series: glycerolipids. DGAT enzymes and triacylglycerol biosynthesis.
Volume: 49
Issue: 11
Pages: 2283-301
Publication
First Author: McFie PJ
Year: 2010
Journal: J Biol Chem
Title: Topological orientation of acyl-CoA:diacylglycerol acyltransferase-1 (DGAT1) and identification of a putative active site histidine and the role of the n terminus in dimer/tetramer formation.
Volume: 285
Issue: 48
Pages: 37377-87
Publication
First Author: Ma Z
Year: 2017
Journal: J Lipid Res
Title: Synthesis of neutral ether lipid monoalkyl-diacylglycerol by lipid acyltransferases.
Volume: 58
Issue: 6
Pages: 1091-1099
Publication  
First Author: Wunderling K
Year: 2021
Journal: Mol Metab
Title: Hepatic synthesis of triacylglycerols containing medium-chain fatty acids is dominated by diacylglycerol acyltransferase 1 and efficiently inhibited by etomoxir.
Volume: 45
Pages: 101150
Publication
First Author: Chen HC
Year: 2004
Journal: Diabetes
Title: Role of adipocyte-derived factors in enhancing insulin signaling in skeletal muscle and white adipose tissue of mice lacking Acyl CoA:diacylglycerol acyltransferase 1.
Volume: 53
Issue: 6
Pages: 1445-51
Publication
First Author: Villanueva CJ
Year: 2009
Journal: Hepatology
Title: Specific role for acyl CoA:Diacylglycerol acyltransferase 1 (Dgat1) in hepatic steatosis due to exogenous fatty acids.
Volume: 50
Issue: 2
Pages: 434-42
Publication
First Author: Liu L
Year: 2014
Journal: J Biol Chem
Title: Cardiomyocyte-specific loss of diacylglycerol acyltransferase 1 (DGAT1) reproduces the abnormalities in lipids found in severe heart failure.
Volume: 289
Issue: 43
Pages: 29881-91
Publication
First Author: Winter A
Year: 2002
Journal: Proc Natl Acad Sci U S A
Title: Association of a lysine-232/alanine polymorphism in a bovine gene encoding acyl-CoA:diacylglycerol acyltransferase (DGAT1) with variation at a quantitative trait locus for milk fat content.
Volume: 99
Issue: 14
Pages: 9300-5
Publication
First Author: Liu L
Year: 2009
Journal: Diabetes
Title: Paradoxical coupling of triglyceride synthesis and fatty acid oxidation in skeletal muscle overexpressing DGAT1.
Volume: 58
Issue: 11
Pages: 2516-24
Publication
First Author: Glenn DJ
Year: 2011
Journal: Hypertension
Title: A murine model of isolated cardiac steatosis leads to cardiomyopathy.
Volume: 57
Issue: 2
Pages: 216-22
Publication
First Author: Chen HC
Year: 2002
Journal: J Clin Invest
Title: Increased insulin and leptin sensitivity in mice lacking acyl CoA:diacylglycerol acyltransferase 1.
Volume: 109
Issue: 8
Pages: 1049-55
Publication
First Author: Chen HC
Year: 2002
Journal: Endocrinology
Title: Deficiency of acyl coenzyme a:diacylglycerol acyltransferase 1 increases leptin sensitivity in murine obesity models.
Volume: 143
Issue: 8
Pages: 2893-8
Publication
First Author: Chen HC
Year: 2002
Journal: J Clin Invest
Title: Leptin modulates the effects of acyl CoA:diacylglycerol acyltransferase deficiency on murine fur and sebaceous glands.
Volume: 109
Issue: 2
Pages: 175-81
Publication
First Author: Yu YH
Year: 2002
Journal: J Biol Chem
Title: Posttranscriptional control of the expression and function of diacylglycerol acyltransferase-1 in mouse adipocytes.
Volume: 277
Issue: 52
Pages: 50876-84
Publication
First Author: Roe ND
Year: 2018
Journal: Sci Rep
Title: The Role of Diacylglycerol Acyltransferase (DGAT) 1 and 2 in Cardiac Metabolism and Function.
Volume: 8
Issue: 1
Pages: 4983
Publication
First Author: Yamazaki T
Year: 2005
Journal: J Biol Chem
Title: Increased very low density lipoprotein secretion and gonadal fat mass in mice overexpressing liver DGAT1.
Volume: 280
Issue: 22
Pages: 21506-14
Publication
First Author: Uchida A
Year: 2013
Journal: Biochim Biophys Acta
Title: Intestinal acyl-CoA:diacylglycerol acyltransferase 2 overexpression enhances postprandial triglyceridemic response and exacerbates high fat diet-induced hepatic triacylglycerol storage.
Volume: 1831
Issue: 8
Pages: 1377-85
Publication    
First Author: Chitraju C
Year: 2023
Journal: Elife
Title: Mice lacking triglyceride synthesis enzymes in adipose tissue are resistant to diet-induced obesity.
Volume: 12
Publication
First Author: Cases S
Year: 2001
Journal: J Biol Chem
Title: Cloning of DGAT2, a second mammalian diacylglycerol acyltransferase, and related family members.
Volume: 276
Issue: 42
Pages: 38870-6
Publication
First Author: Chandak PG
Year: 2011
Journal: Biochim Biophys Acta
Title: Lack of acyl-CoA:diacylglycerol acyltransferase 1 reduces intestinal cholesterol absorption and attenuates atherosclerosis in apolipoprotein E knockout mice.
Volume: 1811
Issue: 12
Pages: 1011-20
Publication
First Author: Vujic N
Year: 2016
Journal: PLoS One
Title: Acyl-CoA:Diacylglycerol Acyltransferase 1 Expression Level in the Hematopoietic Compartment Impacts Inflammation in the Vascular Plaques of Atherosclerotic Mice.
Volume: 11
Issue: 5
Pages: e0156364
Publication
First Author: Kaylor JJ
Year: 2015
Journal: PLoS One
Title: Diacylglycerol O-acyltransferase type-1 synthesizes retinyl esters in the retina and retinal pigment epithelium.
Volume: 10
Issue: 5
Pages: e0125921
Publication
First Author: Guo W
Year: 2021
Journal: Cell Mol Gastroenterol Hepatol
Title: Fatty Acids Inhibit LAMP2-Mediated Autophagy Flux via Activating ER Stress Pathway in Alcohol-Related Liver Disease.
Volume: 12
Issue: 5
Pages: 1599-1615
Publication
First Author: Robblee MM
Year: 2016
Journal: Cell Rep
Title: Saturated Fatty Acids Engage an IRE1α-Dependent Pathway to Activate the NLRP3 Inflammasome in Myeloid Cells.
Volume: 14
Issue: 11
Pages: 2611-23
Publication
First Author: Wongsiriroj N
Year: 2008
Journal: J Biol Chem
Title: The molecular basis of retinoid absorption: a genetic dissection.
Volume: 283
Issue: 20
Pages: 13510-9
Publication
First Author: Harris CA
Year: 2011
Journal: J Lipid Res
Title: DGAT enzymes are required for triacylglycerol synthesis and lipid droplets in adipocytes.
Volume: 52
Issue: 4
Pages: 657-67
Publication
First Author: Stone SJ
Year: 2004
Journal: J Biol Chem
Title: Lipopenia and skin barrier abnormalities in DGAT2-deficient mice.
Volume: 279
Issue: 12
Pages: 11767-76
Publication
First Author: Liu Y
Year: 2008
Journal: Biochim Biophys Acta
Title: Knockdown of acyl-CoA:diacylglycerol acyltransferase 2 with antisense oligonucleotide reduces VLDL TG and ApoB secretion in mice.
Volume: 1781
Issue: 3
Pages: 97-104
Publication
First Author: Paglialunga S
Year: 2008
Journal: Am J Physiol Endocrinol Metab
Title: Acylation-stimulating protein deficiency and altered adipose tissue in alternative complement pathway knockout mice.
Volume: 294
Issue: 3
Pages: E521-9
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Smith SJ
Year: 2000
Journal: Nat Genet
Title: Obesity resistance and multiple mechanisms of triglyceride synthesis in mice lacking Dgat.
Volume: 25
Issue: 1
Pages: 87-90
Publication
First Author: Chen HC
Year: 2003
Journal: Am J Physiol Endocrinol Metab
Title: Analysis of energy expenditure at different ambient temperatures in mice lacking DGAT1.
Volume: 284
Issue: 1
Pages: E213-8
Publication
First Author: Buhman KF
Year: 2000
Journal: Biochim Biophys Acta
Title: Mammalian acyl-CoA:cholesterol acyltransferases.
Volume: 1529
Issue: 1-3
Pages: 142-54
Publication
First Author: Nykiforuk CL
Year: 2002
Journal: Biochim Biophys Acta
Title: Characterization of cDNAs encoding diacylglycerol acyltransferase from cultures of Brassica napus and sucrose-mediated induction of enzyme biosynthesis.
Volume: 1580
Issue: 2-3
Pages: 95-109
GXD Expression      
Probe: MGI:3050118
Assay Type: RT-PCR
Annotation Date: 2004-08-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1752727
Stage: TS27
Assay Id: MGI:3050133
Age: postnatal day 1
Specimen Label: Dermis
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:3050118
Assay Type: RT-PCR
Annotation Date: 2004-08-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1752827
Stage: TS27
Assay Id: MGI:3050133
Age: postnatal day 1
Specimen Label: Epidermis
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:3050118
Assay Type: RT-PCR
Annotation Date: 2004-08-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3568928
Stage: TS28
Assay Id: MGI:3050137
Age: embryonic day 9.5
Image: 3
Specimen Label: Placenta
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:3050118
Assay Type: RT-PCR
Annotation Date: 2004-08-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3568928
Stage: TS28
Assay Id: MGI:3050137
Age: embryonic day 13.5
Image: 3
Specimen Label: Placenta
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:3050118
Assay Type: RT-PCR
Annotation Date: 2004-08-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3568928
Stage: TS28
Assay Id: MGI:3050137
Age: embryonic day 18.5
Image: 3
Specimen Label: Placenta
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:3050118
Assay Type: RT-PCR
Annotation Date: 2004-08-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1608515
Stage: TS15
Assay Id: MGI:3050137
Age: embryonic day 9.5
Image: 3
Specimen Label: Yolk Sac
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:3050118
Assay Type: RT-PCR
Annotation Date: 2004-08-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1608521
Stage: TS21
Assay Id: MGI:3050137
Age: embryonic day 13.5
Image: 3
Specimen Label: Yolk Sac
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:3050118
Assay Type: RT-PCR
Annotation Date: 2004-08-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1608526
Stage: TS26
Assay Id: MGI:3050137
Age: embryonic day 18.5
Image: 3
Specimen Label: Yolk Sac
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:3050118
Assay Type: RT-PCR
Annotation Date: 2004-08-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603915
Stage: TS15
Assay Id: MGI:3050137
Age: embryonic day 9.5
Image: 3
Specimen Label: Embryo
Detected: true
Specimen Num: 7
GXD Expression    
Probe: MGI:3050118
Assay Type: RT-PCR
Annotation Date: 2004-08-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603921
Stage: TS21
Assay Id: MGI:3050137
Age: embryonic day 13.5
Image: 3
Specimen Label: Embryo
Detected: true
Specimen Num: 8
GXD Expression    
Probe: MGI:3050118
Assay Type: RT-PCR
Annotation Date: 2004-08-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603926
Stage: TS26
Assay Id: MGI:3050137
Age: embryonic day 18.5
Image: 3
Specimen Label: Embryo
Detected: true
Specimen Num: 9
GXD Expression    
Probe: MGI:3050118
Assay Type: RT-PCR
Annotation Date: 2004-08-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:3050137
Age: postnatal adult
Image: 3
Specimen Label: Adult Liver
Detected: true
Specimen Num: 10