Type |
Details |
Score |
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
frog, western clawed |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
hamster, Chinese |
|
•
•
•
•
•
|
Gene |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chimpanzee |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
dog, domestic |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
cattle |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chicken |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
zebrafish |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
macaque, rhesus |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Family |
Description: |
Dihydrofolate reductase (DHFR) () catalyses the NADPH-dependent reduction of dihydrofolate to tetrahydrofolate, an essential step in de novosynthesis both of glycine and of purines and deoxythymidine phosphate (the precursors of DNA synthesis) [], and important also in the conversion of deoxyuridine monophosphate to deoxythymidine monophosphate. Although DHFR is found ubiquitously in prokaryotes and eukaryotes, and is found in all dividing cells, maintaining levels of fully reduced folate coenzymes, the catabolic steps are still not well understood [].Bacterial species possesses distinct DHFR enzymes (based on their pattern of binding diaminoheterocyclic molecules), but mammalian DHFRs are highly similar []. The active site is situated in the N-terminal half of the sequence, which includes a conserved Pro-Trp dipeptide; the tryptophan has been shown []to be involved in the binding of substrate by the enzyme. Its central role in DNA precursor synthesis, coupled with its inhibition by antagonists such as trimethoprim and methotrexate, which are used as anti-bacterial or anti-cancer agents, has made DHFR a target of anticancer chemotherapy. However, resistance has developed against some drugs, as a result of changes in DHFR itself []. |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Publication |
First Author: |
Snapka RM |
Year: |
1997 |
Journal: |
Cell Prolif |
Title: |
Unbalanced growth in mouse cells with amplified dhfr genes. |
Volume: |
30 |
Issue: |
10-12 |
Pages: |
385-99 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
187
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
187
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Smith SL |
Year: |
1979 |
Journal: |
J Biol Chem |
Title: |
Porcine liver dihydrofolate reductase. Purification, properties, and amino acid sequence. |
Volume: |
254 |
Issue: |
22 |
Pages: |
11475-84 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bolin JT |
Year: |
1982 |
Journal: |
J Biol Chem |
Title: |
Crystal structures of Escherichia coli and Lactobacillus casei dihydrofolate reductase refined at 1.7 A resolution. I. General features and binding of methotrexate. |
Volume: |
257 |
Issue: |
22 |
Pages: |
13650-62 |
|
•
•
•
•
•
|
Publication |
First Author: |
Cowman AF |
Year: |
1989 |
Journal: |
Mol Cell Biol |
Title: |
Antifolate drug selection results in duplication and rearrangement of chromosome 7 in Plasmodium chabaudi. |
Volume: |
9 |
Issue: |
11 |
Pages: |
5182-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Oefner C |
Year: |
1988 |
Journal: |
Eur J Biochem |
Title: |
Crystal structure of human dihydrofolate reductase complexed with folate. |
Volume: |
174 |
Issue: |
2 |
Pages: |
377-85 |
|
•
•
•
•
•
|
Publication |
First Author: |
Trimble JJ |
Year: |
1988 |
Journal: |
Science |
Title: |
A gene for dihydrofolate reductase in a herpesvirus. |
Volume: |
239 |
Issue: |
4844 |
Pages: |
1145-7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Linton JP |
Year: |
1989 |
Journal: |
Mol Cell Biol |
Title: |
Dual bidirectional promoters at the mouse dhfr locus: cloning and characterization of two mRNA classes of the divergently transcribed Rep-1 gene. |
Volume: |
9 |
Issue: |
7 |
Pages: |
3058-72 |
|
•
•
•
•
•
|
Publication |
First Author: |
Thoms JA |
Year: |
2016 |
Journal: |
Mol Cell Biol |
Title: |
Arrested Hematopoiesis and Vascular Relaxation Defects in Mice with a Mutation in Dhfr. |
Volume: |
36 |
Issue: |
8 |
Pages: |
1222-36 |
|
•
•
•
•
•
|
Interaction Term |
|
•
•
•
•
•
|
Publication |
First Author: |
Funanage VL |
Year: |
1984 |
Journal: |
Mol Cell Biol |
Title: |
Assignment of the human dihydrofolate reductase gene to the q11----q22 region of chromosome 5. |
Volume: |
4 |
Issue: |
10 |
Pages: |
2010-6 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hughes L |
Year: |
2015 |
Journal: |
FEBS Lett |
Title: |
An active second dihydrofolate reductase enzyme is not a feature of rat and mouse, but they do have activity in their mitochondria. |
Volume: |
589 |
Issue: |
15 |
Pages: |
1855-62 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hanson C |
Year: |
1990 |
Journal: |
Cytogenet Cell Genet |
Title: |
Assignment of two rat dihydrofolate (DHFR) genes to chromosomes 2 and 4. |
Volume: |
53 |
Issue: |
1 |
Pages: |
23-5 |
|
•
•
•
•
•
|
Publication |
First Author: |
Crouse GF |
Year: |
1982 |
Journal: |
J Biol Chem |
Title: |
Structure of amplified normal and variant dihydrofolate reductase genes in mouse sarcoma S180 cells. |
Volume: |
257 |
Issue: |
13 |
Pages: |
7887-97 |
|
•
•
•
•
•
|
Publication |
First Author: |
Means AL |
Year: |
1992 |
Journal: |
Mol Cell Biol |
Title: |
The HIP1 binding site is required for growth regulation of the dihydrofolate reductase gene promoter. |
Volume: |
12 |
Issue: |
3 |
Pages: |
1054-63 |
|
•
•
•
•
•
|
Publication |
First Author: |
Crabtree MJ |
Year: |
2011 |
Journal: |
Free Radic Biol Med |
Title: |
Dihydrofolate reductase protects endothelial nitric oxide synthase from uncoupling in tetrahydrobiopterin deficiency. |
Volume: |
50 |
Issue: |
11 |
Pages: |
1639-46 |
|
•
•
•
•
•
|
Publication |
First Author: |
Li Q |
Year: |
2019 |
Journal: |
Redox Biol |
Title: |
Knockout of dihydrofolate reductase in mice induces hypertension and abdominal aortic aneurysm via mitochondrial dysfunction. |
Volume: |
24 |
|
Pages: |
101185 |
|
•
•
•
•
•
|
Publication |
First Author: |
Blakley RL |
Year: |
1998 |
Journal: |
Hum Mutat |
Title: |
In vitro mutations in dihydrofolate reductase that confer resistance to methotrexate: potential for clinical application. |
Volume: |
11 |
Issue: |
4 |
Pages: |
259-63 |
|
•
•
•
•
•
|
Publication |
First Author: |
Schreiner B |
Year: |
2012 |
Journal: |
Mol Biol Cell |
Title: |
Role of the AAA protease Yme1 in folding of proteins in the intermembrane space of mitochondria. |
Volume: |
23 |
Issue: |
22 |
Pages: |
4335-46 |
|
•
•
•
•
•
|
Publication |
First Author: |
Killary AM |
Year: |
1986 |
Journal: |
Somat Cell Mol Genet |
Title: |
Assignment of genes encoding dihydrofolate reductase and hexosaminidase B to Mus musculus chromosome 13. |
Volume: |
12 |
Issue: |
6 |
Pages: |
641-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Johnson LF |
Year: |
1978 |
Journal: |
J Cell Physiol |
Title: |
Regulation of dihydrofolate reductase gene expression in mouse fibroblasts during the transition from the resting to growing state. |
Volume: |
97 |
Issue: |
3 Pt 2 Suppl 1 |
Pages: |
397-306 |
|
•
•
•
•
•
|
Publication |
First Author: |
Crouse GF |
Year: |
1983 |
Journal: |
Mol Cell Biol |
Title: |
Expression and amplification of engineered mouse dihydrofolate reductase minigenes. |
Volume: |
3 |
Issue: |
2 |
Pages: |
257-66 |
|
•
•
•
•
•
|
Publication |
First Author: |
Chen MJ |
Year: |
1984 |
Journal: |
J Biol Chem |
Title: |
The functional human dihydrofolate reductase gene. |
Volume: |
259 |
Issue: |
6 |
Pages: |
3933-43 |
|
•
•
•
•
•
|
Publication |
First Author: |
James RI |
Year: |
1997 |
Journal: |
Exp Hematol |
Title: |
Transgenic mice expressing the tyr22 variant of murine DHFR: protection of transgenic marrow transplant recipients from lethal doses of methotrexate. |
Volume: |
25 |
Issue: |
12 |
Pages: |
1286-95 |
|
•
•
•
•
•
|
Publication |
First Author: |
Cai Z |
Year: |
2015 |
Journal: |
Arterioscler Thromb Vasc Biol |
Title: |
Endothelial Nitric Oxide Synthase-Derived Nitric Oxide Prevents Dihydrofolate Reductase Degradation via Promoting S-Nitrosylation. |
Volume: |
35 |
Issue: |
11 |
Pages: |
2366-73 |
|
•
•
•
•
•
|
Publication |
First Author: |
Crabtree MJ |
Year: |
2009 |
Journal: |
J Biol Chem |
Title: |
Critical role for tetrahydrobiopterin recycling by dihydrofolate reductase in regulation of endothelial nitric-oxide synthase coupling: relative importance of the de novo biopterin synthesis versus salvage pathways. |
Volume: |
284 |
Issue: |
41 |
Pages: |
28128-36 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kuzumaki T |
Year: |
1996 |
Journal: |
Biochim Biophys Acta |
Title: |
Cell adhesion to substratum and activation of tyrosine kinases are essentially required for G1/S phase transition in BALB/c 3T3 fibroblasts. |
Volume: |
1310 |
Issue: |
2 |
Pages: |
185-92 |
|
•
•
•
•
•
|
Publication |
First Author: |
Fry CJ |
Year: |
1997 |
Journal: |
Mol Cell Biol |
Title: |
Position-dependent transcriptional regulation of the murine dihydrofolate reductase promoter by the E2F transactivation domain. |
Volume: |
17 |
Issue: |
4 |
Pages: |
1966-76 |
|
•
•
•
•
•
|
Publication |
First Author: |
Killary AM |
Year: |
1986 |
Journal: |
Am J Hum Genet |
Title: |
Assignment of the genes encoding dihydrofolate reductase and hexosaminidase B to mouse Chromosome 13 |
Volume: |
39 |
Issue: |
Suppl |
Pages: |
A159 (Abstr.) |
|
•
•
•
•
•
|
Publication |
First Author: |
Smith ML |
Year: |
1990 |
Journal: |
Mol Cell Biol |
Title: |
Analysis of the mouse Dhfr/Rep-3 major promoter region by using linker-scanning and internal deletion mutations and DNase I footprinting. |
Volume: |
10 |
Issue: |
11 |
Pages: |
6003-12 |
|
•
•
•
•
•
|
Publication |
First Author: |
Saha S |
Year: |
2023 |
Journal: |
Development |
Title: |
Dihydrofolate reductase activity controls neurogenic transitions in the developing neocortex. |
Volume: |
150 |
Issue: |
20 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Weng Q |
Year: |
2017 |
Journal: |
Sci Rep |
Title: |
Folate Metabolism Regulates Oligodendrocyte Survival and Differentiation by Modulating AMPKα Activity. |
Volume: |
7 |
Issue: |
1 |
Pages: |
1705 |
|
•
•
•
•
•
|
Publication |
First Author: |
Beecham EJ |
Year: |
1997 |
Journal: |
Carcinogenesis |
Title: |
Decoupling of DNA excision repair and RNA transcription in translocation breaksite regions of plasmacytoma-susceptible BALB/cAnPt mice. |
Volume: |
18 |
Issue: |
4 |
Pages: |
687-94 |
|
•
•
•
•
•
|
Publication |
First Author: |
Newton G |
Year: |
1999 |
Journal: |
Mamm Genome |
Title: |
The thrombospondin-4 gene. |
Volume: |
10 |
Issue: |
10 |
Pages: |
1010-6 |
|
•
•
•
•
•
|
Publication |
First Author: |
Cao Y |
Year: |
2019 |
Journal: |
Mol Cell Biochem |
Title: |
Endothelial retinoblastoma protein reduces abdominal aortic aneurysm development via promoting DHFR/NO pathway-mediated vasoprotection. |
Volume: |
460 |
Issue: |
1-2 |
Pages: |
29-36 |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus caroli |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus pahari |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus spretus |
|
•
•
•
•
•
|
Publication |
First Author: |
Simonsen CC |
Year: |
1983 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Isolation and expression of an altered mouse dihydrofolate reductase cDNA. |
Volume: |
80 |
Issue: |
9 |
Pages: |
2495-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Chang AC |
Year: |
1978 |
Journal: |
Nature |
Title: |
Phenotypic expression in E. coli of a DNA sequence coding for mouse dihydrofolate reductase. |
Volume: |
275 |
Issue: |
5681 |
Pages: |
617-24 |
|
•
•
•
•
•
|
Publication |
First Author: |
Tauro GP |
Year: |
1976 |
Journal: |
N Engl J Med |
Title: |
Dihydrofolate reductase deficiency causing megaloblastic anemia in two families. |
Volume: |
294 |
Issue: |
9 |
Pages: |
466-70 |
|
•
•
•
•
•
|
Publication |
First Author: |
Alt FW |
Year: |
1978 |
Journal: |
J Biol Chem |
Title: |
Selective multiplication of dihydrofolate reductase genes in methotrexate-resistant variants of cultured murine cells. |
Volume: |
253 |
Issue: |
5 |
Pages: |
1357-70 |
|
•
•
•
•
•
|
Publication |
First Author: |
Schimke RT |
Year: |
1978 |
Journal: |
Science |
Title: |
Gene amplification and drug resistance in cultured murine cells. |
Volume: |
202 |
Issue: |
4372 |
Pages: |
1051-5 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lee F |
Year: |
1981 |
Journal: |
Nature |
Title: |
Glucocorticoids regulate expression of dihydrofolate reductase cDNA in mouse mammary tumour virus chimaeric plasmids. |
Volume: |
294 |
Issue: |
5838 |
Pages: |
228-32 |
|
•
•
•
•
•
|
Publication |
First Author: |
Xu HP |
Year: |
1996 |
Journal: |
Mamm Genome |
Title: |
New polymorphic markers in the vicinity of the pearl locus on mouse chromosome 13. |
Volume: |
7 |
Issue: |
1 |
Pages: |
16-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
HAKALA MT |
Year: |
1961 |
Journal: |
J Biol Chem |
Title: |
Relation of folic acid reductase to amethopterin resistance in cultured mammalian cells. |
Volume: |
236 |
|
Pages: |
952-8 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5466732 |
Assay Type: |
RNase protection |
Annotation Date: |
2013-03-01 |
Strength: |
Not Specified |
Sex: |
Not Specified |
Emaps: |
EMAPS:1684628 |
|
Stage: |
TS28 |
Assay Id: |
MGI:5466745 |
Age: |
postnatal adult |
|
|
Specimen Label: |
liver |
|
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5466732 |
Assay Type: |
RNase protection |
Annotation Date: |
2013-03-01 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1876728 |
|
Stage: |
TS28 |
Assay Id: |
MGI:5466745 |
Age: |
postnatal adult |
|
|
Specimen Label: |
spleen |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5466732 |
Assay Type: |
RNase protection |
Annotation Date: |
2013-03-01 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1737328 |
|
Stage: |
TS28 |
Assay Id: |
MGI:5466745 |
Age: |
postnatal adult |
|
|
Specimen Label: |
kidney |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5466732 |
Assay Type: |
RNase protection |
Annotation Date: |
2013-03-01 |
Strength: |
Not Specified |
Sex: |
Not Specified |
Emaps: |
EMAPS:1778728 |
|
Stage: |
TS28 |
Assay Id: |
MGI:5466745 |
Age: |
postnatal adult |
|
|
Specimen Label: |
cerebellum |
|
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5466732 |
Assay Type: |
RNase protection |
Annotation Date: |
2013-03-01 |
Strength: |
Not Specified |
Sex: |
Not Specified |
Emaps: |
EMAPS:1691028 |
|
Stage: |
TS28 |
Assay Id: |
MGI:5466745 |
Age: |
postnatal adult |
|
|
Specimen Label: |
cerebrum |
|
Specimen Num: |
5 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5466732 |
Assay Type: |
RNase protection |
Annotation Date: |
2013-03-01 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1876828 |
|
Stage: |
TS28 |
Assay Id: |
MGI:5466745 |
Age: |
postnatal adult |
|
|
Specimen Label: |
thymus |
Detected: |
true |
Specimen Num: |
6 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5466732 |
Assay Type: |
RNase protection |
Annotation Date: |
2013-03-01 |
Strength: |
Not Specified |
Sex: |
Not Specified |
Emaps: |
EMAPS:3263428 |
|
Stage: |
TS28 |
Assay Id: |
MGI:5466745 |
Age: |
postnatal adult |
|
|
Specimen Label: |
thigh muscle |
|
Specimen Num: |
7 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5466732 |
Assay Type: |
RNase protection |
Annotation Date: |
2013-03-01 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3185820 |
|
Stage: |
TS20 |
Assay Id: |
MGI:5466755 |
Age: |
embryonic day 12.5 |
|
|
Specimen Label: |
FACE |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5466732 |
Assay Type: |
RNase protection |
Annotation Date: |
2013-03-01 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3185720 |
|
Stage: |
TS20 |
Assay Id: |
MGI:5466755 |
Age: |
embryonic day 12.5 |
|
|
Specimen Label: |
BODY |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5466732 |
Assay Type: |
RNase protection |
Annotation Date: |
2013-03-01 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1689521 |
|
Stage: |
TS21 |
Assay Id: |
MGI:5466755 |
Age: |
embryonic day 13.5 |
|
|
Specimen Label: |
Forebrain |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5466732 |
Assay Type: |
RNase protection |
Annotation Date: |
2013-03-01 |
Strength: |
Not Specified |
Sex: |
Not Specified |
Emaps: |
EMAPS:1691621 |
|
Stage: |
TS21 |
Assay Id: |
MGI:5466755 |
Age: |
embryonic day 13.5 |
|
|
Specimen Label: |
Hindbrain |
|
Specimen Num: |
5 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5466732 |
Assay Type: |
RNase protection |
Annotation Date: |
2013-03-01 |
Strength: |
Not Specified |
Sex: |
Not Specified |
Emaps: |
EMAPS:1757721 |
|
Stage: |
TS21 |
Assay Id: |
MGI:5466755 |
Age: |
embryonic day 13.5 |
|
|
Specimen Label: |
Spinal cord |
|
Specimen Num: |
6 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5466732 |
Assay Type: |
RNase protection |
Annotation Date: |
2013-03-01 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3185821 |
|
Stage: |
TS21 |
Assay Id: |
MGI:5466755 |
Age: |
embryonic day 13.5 |
|
|
Specimen Label: |
Face |
Detected: |
true |
Specimen Num: |
7 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5466732 |
Assay Type: |
RNase protection |
Annotation Date: |
2013-03-01 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:1684621 |
|
Stage: |
TS21 |
Assay Id: |
MGI:5466755 |
Age: |
embryonic day 13.5 |
|
|
Specimen Label: |
Liver/gut |
Detected: |
false |
Specimen Num: |
8 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5466732 |
Assay Type: |
RNase protection |
Annotation Date: |
2013-03-01 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:1624721 |
|
Stage: |
TS21 |
Assay Id: |
MGI:5466755 |
Age: |
embryonic day 13.5 |
|
|
Specimen Label: |
Liver/gut |
Detected: |
false |
Specimen Num: |
8 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5466732 |
Assay Type: |
RNase protection |
Annotation Date: |
2013-03-01 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3185721 |
|
Stage: |
TS21 |
Assay Id: |
MGI:5466755 |
Age: |
embryonic day 13.5 |
|
|
Specimen Label: |
Body |
Detected: |
true |
Specimen Num: |
9 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5466732 |
Assay Type: |
RNase protection |
Annotation Date: |
2013-03-01 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1672821 |
|
Stage: |
TS21 |
Assay Id: |
MGI:5466755 |
Age: |
embryonic day 13.5 |
|
|
Specimen Label: |
Heart/lungs |
Detected: |
true |
Specimen Num: |
10 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5466732 |
Assay Type: |
RNase protection |
Annotation Date: |
2013-03-01 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1610521 |
|
Stage: |
TS21 |
Assay Id: |
MGI:5466755 |
Age: |
embryonic day 13.5 |
|
|
Specimen Label: |
Heart/lungs |
Detected: |
true |
Specimen Num: |
10 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5466732 |
Assay Type: |
RNase protection |
Annotation Date: |
2013-03-01 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1640521 |
|
Stage: |
TS21 |
Assay Id: |
MGI:5466755 |
Age: |
embryonic day 13.5 |
|
|
Specimen Label: |
Limbs |
Detected: |
true |
Specimen Num: |
11 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5466732 |
Assay Type: |
RNase protection |
Annotation Date: |
2013-03-01 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1608521 |
|
Stage: |
TS21 |
Assay Id: |
MGI:5466755 |
Age: |
embryonic day 13.5 |
|
|
Specimen Label: |
Yolk sac |
Detected: |
true |
Specimen Num: |
12 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6196092 |
Assay Type: |
RT-PCR |
Annotation Date: |
2018-08-30 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1684621 |
|
Stage: |
TS21 |
Assay Id: |
MGI:6196094 |
Age: |
embryonic day 13.5 |
|
|
Specimen Label: |
+/+ |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6196092 |
Assay Type: |
RT-PCR |
Annotation Date: |
2018-08-30 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1684621 |
|
Stage: |
TS21 |
Assay Id: |
MGI:6196094 |
Age: |
embryonic day 13.5 |
|
|
Specimen Label: |
+/Ora |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6196092 |
Assay Type: |
RT-PCR |
Annotation Date: |
2018-08-30 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1684621 |
|
Stage: |
TS21 |
Assay Id: |
MGI:6196094 |
Age: |
embryonic day 13.5 |
|
|
Specimen Label: |
Ora/Ora |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6196092 |
Assay Type: |
RT-PCR |
Annotation Date: |
2018-08-30 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1684628 |
|
Stage: |
TS28 |
Assay Id: |
MGI:6196095 |
Age: |
postnatal adult |
|
|
Specimen Label: |
+/+ |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6196092 |
Assay Type: |
RT-PCR |
Annotation Date: |
2018-08-30 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1684628 |
|
Stage: |
TS28 |
Assay Id: |
MGI:6196095 |
Age: |
postnatal adult |
|
|
Specimen Label: |
+/Ora |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|