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Search results 1 to 100 out of 802 for Dhh

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Type Details Score
Gene
Type: gene
Organism: Not Specified
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: chimpanzee
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: zebrafish
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: rat
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
GXD Expression
Probe: MGI:6117269
Assay Type: RNA in situ
Annotation Date: 2018-02-21
Strength: Present
Sex: Male
Emaps: EMAPS:1797220
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:6117297
Age: embryonic day 12.5
Image: 6 Dhh -/-
Note: Authors report a reduction in formation of testicular cords in the cortical coelomic region in mutant gonads compared with wild-type.
Specimen Label: 6 Dhh -/-
Detected: true
Specimen Num: 5
GXD Expression  
Probe: MGI:6117269
Assay Type: RNA in situ
Annotation Date: 2018-02-21
Strength: Present
Sex: Male
Emaps: EMAPS:1797220
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:6117297
Age: embryonic day 12.5
Image: 6 Dhh (right pane)
Specimen Label: 6 Dhh (right pane)
Detected: true
Specimen Num: 6
GXD Expression
Probe: MGI:6117269
Assay Type: RNA in situ
Annotation Date: 2018-02-21
Strength: Weak
Sex: Male
Emaps: EMAPS:1738319
Pattern: Regionally restricted
Stage: TS19
Assay Id: MGI:6117297
Age: embryonic day 11.5
Image: 1A Dhh -/-
Note: Authors report a significant reduction in Sertoli cells in mutant gonads compared with wild-type.
Specimen Label: 1A Dhh -/-
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:6117269
Assay Type: RNA in situ
Annotation Date: 2018-02-21
Strength: Present
Sex: Male
Emaps: EMAPS:1738319
Pattern: Regionally restricted
Stage: TS19
Assay Id: MGI:6117297
Age: embryonic day 11.5
Image: 1A Dhh (right pane)
Specimen Label: 1A Dhh (right pane)
Detected: true
Specimen Num: 2
Publication
First Author: Liu C
Year: 2018
Journal: Endocrinology
Title: Reproductive, Physiological, and Molecular Outcomes in Female Mice Deficient in Dhh and Ihh.
Volume: 159
Issue: 7
Pages: 2563-2575
Publication
First Author: Norris AM
Year: 2023
Journal: Nat Commun
Title: Hedgehog signaling via its ligand DHH acts as cell fate determinant during skeletal muscle regeneration.
Volume: 14
Issue: 1
Pages: 3766
Publication
First Author: Hollier PL
Year: 2021
Journal: Cardiovasc Res
Title: Full-length Dhh and N-terminal Shh act as competitive antagonists to regulate angiogenesis and vascular permeability.
Volume: 117
Issue: 12
Pages: 2489-2501
Publication
First Author: La Sala G
Year: 2015
Journal: FASEB J
Title: Modulation of Dhh signaling and altered Sertoli cell function in mice lacking the GPR37-prosaposin receptor.
Volume: 29
Issue: 5
Pages: 2059-69
Publication
First Author: Molstad DHH
Year: 2020
Journal: J Biol Chem
Title: Hdac3 regulates bone modeling by suppressing osteoclast responsiveness to RANKL.
Volume: 295
Issue: 51
Pages: 17713-17723
GXD Expression
Probe: MGI:1314968
Assay Type: Immunohistochemistry
Annotation Date: 2021-06-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1787127
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:6718503
Age: postnatal day 0
Image: 5C Dhh cKO 3D
Note: Reduced expression compared with the control.
Specimen Label: 5C Dhh cKO 3D
Detected: true
Specimen Num: 7
GXD Expression
Probe: MGI:1314968
Assay Type: Immunohistochemistry
Annotation Date: 2021-06-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1787127
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:6718503
Age: postnatal day 0
Image: 5C Dhh cKO 2
Note: Reduced expression compared with the control.
Specimen Label: 5C Dhh cKO 2
Detected: true
Specimen Num: 8
Publication
First Author: Molstad DHH
Year: 2020
Journal: Sci Rep
Title: Hdac3 deletion in myeloid progenitor cells enhances bone healing in females and limits osteoclast fusion via Pmepa1.
Volume: 10
Issue: 1
Pages: 21804
UniProt Feature
Begin: 106
Description: DHH motif
Type: short sequence motif
End: 108
UniProt Feature
Begin: 109
Description: DHH motif
Type: short sequence motif
End: 111
Protein
Organism: Mus musculus/domesticus
Length: 396  
Fragment?: false
Author
Protein
Organism: Mus musculus/domesticus
Length: 263  
Fragment?: false
Publication
First Author: Yamagata A
Year: 2002
Journal: Proc Natl Acad Sci U S A
Title: The crystal structure of exonuclease RecJ bound to Mn2+ ion suggests how its characteristic motifs are involved in exonuclease activity.
Volume: 99
Issue: 9
Pages: 5908-12
Protein Domain
Type: Homologous_superfamily
Description: DHH phosphoesterase superfamily includes manganese-dependent inorganic pyrophosphatase (family II), Drosophila prune protein and bacterial RecJ exonuclease []. Typically, its members consist of two non-similar domains:domain 1 with parallel sheet of 6 strands and domain 2 with mixed sheet of 5 strands.
Publication
First Author: Wu J
Year: 2008
Journal: Cancer Cell
Title: Plexiform and dermal neurofibromas and pigmentation are caused by Nf1 loss in desert hedgehog-expressing cells.
Volume: 13
Issue: 2
Pages: 105-16
Publication
First Author: Umehara F
Year: 2006
Journal: Behav Brain Res
Title: Elevated anxiety-like and depressive behavior in Desert hedgehog knockout male mice.
Volume: 174
Issue: 1
Pages: 167-73
Publication
First Author: Takabatake T
Year: 1997
Journal: FEBS Lett
Title: Hedgehog and patched gene expression in adult ocular tissues.
Volume: 410
Issue: 2-3
Pages: 485-9
Publication
First Author: Bitgood MJ
Year: 1996
Journal: Curr Biol
Title: Sertoli cell signaling by Desert hedgehog regulates the male germline.
Volume: 6
Issue: 3
Pages: 298-304
Publication
First Author: Lau CI
Year: 2012
Journal: Blood
Title: Regulation of murine normal and stress-induced erythropoiesis by Desert Hedgehog.
Volume: 119
Issue: 20
Pages: 4741-51
Publication  
First Author: Jung J
Year: 2015
Journal: Exp Neurol
Title: Desert hedgehog is a mediator of demyelination in compression neuropathies.
Volume: 271
Pages: 84-94
Publication
First Author: Mora P
Year: 2020
Journal: PLoS Biol
Title: Blood-brain barrier genetic disruption leads to protective barrier formation at the Glia Limitans.
Volume: 18
Issue: 11
Pages: e3000946
Publication
First Author: Sharghi-Namini S
Year: 2006
Journal: J Neurosci
Title: The structural and functional integrity of peripheral nerves depends on the glial-derived signal desert hedgehog.
Volume: 26
Issue: 23
Pages: 6364-76
Publication
First Author: Pierucci-Alves F
Year: 2001
Journal: Biol Reprod
Title: A developmental study of the Desert hedgehog-null mouse testis.
Volume: 65
Issue: 5
Pages: 1392-402
Publication
First Author: Küspert M
Year: 2012
Journal: J Neurosci
Title: Desert hedgehog links transcription factor Sox10 to perineurial development.
Volume: 32
Issue: 16
Pages: 5472-80
Publication
First Author: Renault MA
Year: 2013
Journal: Arterioscler Thromb Vasc Biol
Title: Hedgehog-dependent regulation of angiogenesis and myogenesis is impaired in aged mice.
Volume: 33
Issue: 12
Pages: 2858-66
Publication
First Author: Parmantier E
Year: 1999
Journal: Neuron
Title: Schwann cell-derived Desert hedgehog controls the development of peripheral nerve sheaths.
Volume: 23
Issue: 4
Pages: 713-24
Publication
First Author: Caradu C
Year: 2018
Journal: Circ Res
Title: Restoring Endothelial Function by Targeting Desert Hedgehog Downstream of Klf2 Improves Critical Limb Ischemia in Adults.
Volume: 123
Issue: 9
Pages: 1053-1065
Publication
First Author: Fulmer D
Year: 2020
Journal: Dev Biol
Title: Desert hedgehog-primary cilia cross talk shapes mitral valve tissue by organizing smooth muscle actin.
Volume: 463
Issue: 1
Pages: 26-38
Publication
First Author: Clark AM
Year: 2000
Journal: Biol Reprod
Title: Desert hedgehog (Dhh) gene is required in the mouse testis for formation of adult-type Leydig cells and normal development of peritubular cells and seminiferous tubules.
Volume: 63
Issue: 6
Pages: 1825-38
Publication
First Author: Chapouly C
Year: 2016
Journal: Cardiovasc Res
Title: Impaired Hedgehog signalling-induced endothelial dysfunction is sufficient to induce neuropathy: implication in diabetes.
Volume: 109
Issue: 2
Pages: 217-27
Publication
First Author: Renault MA
Year: 2013
Journal: Circ Res
Title: Desert hedgehog promotes ischemia-induced angiogenesis by ensuring peripheral nerve survival.
Volume: 112
Issue: 5
Pages: 762-70
Publication
First Author: Chapouly C
Year: 2020
Journal: Arterioscler Thromb Vasc Biol
Title: Desert Hedgehog-Driven Endothelium Integrity Is Enhanced by Gas1 (Growth Arrest-Specific 1) but Negatively Regulated by Cdon (Cell Adhesion Molecule-Related/Downregulated by Oncogenes).
Volume: 40
Issue: 12
Pages: e336-e349
Publication
First Author: Carpenter D
Year: 1998
Journal: Proc Natl Acad Sci U S A
Title: Characterization of two patched receptors for the vertebrate hedgehog protein family.
Volume: 95
Issue: 23
Pages: 13630-4
Publication
First Author: Bitgood MJ
Year: 1995
Journal: Dev Biol
Title: Hedgehog and Bmp genes are coexpressed at many diverse sites of cell-cell interaction in the mouse embryo.
Volume: 172
Issue: 1
Pages: 126-38
Publication
First Author: Park SY
Year: 2005
Journal: Development
Title: Nuclear receptors Sf1 and Dax1 function cooperatively to mediate somatic cell differentiation during testis development.
Volume: 132
Issue: 10
Pages: 2415-23
Publication
First Author: Park SY
Year: 2007
Journal: Endocrinology
Title: Distinct roles for steroidogenic factor 1 and desert hedgehog pathways in fetal and adult Leydig cell development.
Volume: 148
Issue: 8
Pages: 3704-10
Publication
First Author: Adolphe C
Year: 2004
Journal: Development
Title: An in vivo comparative study of sonic, desert and Indian hedgehog reveals that hedgehog pathway activity regulates epidermal stem cell homeostasis.
Volume: 131
Issue: 20
Pages: 5009-19
Publication
First Author: Marigo V
Year: 1995
Journal: Genomics
Title: Cloning, expression, and chromosomal location of SHH and IHH: two human homologues of the Drosophila segment polarity gene hedgehog.
Volume: 28
Issue: 1
Pages: 44-51
Publication  
First Author: Kucerova R
Year: 2012
Journal: Mol Vis
Title: Interaction between hedgehog signalling and PAX6 dosage mediates maintenance and regeneration of the corneal epithelium.
Volume: 18
Pages: 139-50
Publication
First Author: Zotter B
Year: 2022
Journal: J Neurosci
Title: Gli1 Regulates the Postnatal Acquisition of Peripheral Nerve Architecture.
Volume: 42
Issue: 2
Pages: 183-201
Publication
First Author: Finzsch M
Year: 2010
Journal: J Cell Biol
Title: Sox10 is required for Schwann cell identity and progression beyond the immature Schwann cell stage.
Volume: 189
Issue: 4
Pages: 701-12
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication  
First Author: Mirsky R
Year: 1999
Journal: Ann N Y Acad Sci
Title: Schwann cell-derived desert hedgehog signals nerve sheath formation.
Volume: 883
Pages: 196-202
Publication
First Author: Furmanski AL
Year: 2013
Journal: J Immunol
Title: Tissue-derived hedgehog proteins modulate Th differentiation and disease.
Volume: 190
Issue: 6
Pages: 2641-9
GXD Expression    
Probe: MGI:1204720
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:1204722
Age: postnatal week 6-8
Image: st96_255
Specimen Label: None
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:1204720
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Absent
Sex: Pooled
Emaps: EMAPS:1754428
Stage: TS28
Assay Id: MGI:1204722
Age: postnatal week 6-8
Image: st96_255
Specimen Label: None
Detected: false
Specimen Num: 2
GXD Expression    
Probe: MGI:1204720
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:3284528
Stage: TS28
Assay Id: MGI:1204722
Age: postnatal week 6-8
Image: st96_255
Specimen Label: None
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:1204720
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Absent
Sex: Pooled
Emaps: EMAPS:1697428
Stage: TS28
Assay Id: MGI:1204722
Age: postnatal week 6-8
Image: st96_255
Specimen Label: None
Detected: false
Specimen Num: 4
GXD Expression    
Probe: MGI:1204720
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Absent
Sex: Pooled
Emaps: EMAPS:1754928
Stage: TS28
Assay Id: MGI:1204722
Age: postnatal week 6-8
Image: st96_255
Specimen Label: None
Detected: false
Specimen Num: 5
GXD Expression    
Probe: MGI:1204720
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Absent
Sex: Pooled
Emaps: EMAPS:3280928
Stage: TS28
Assay Id: MGI:1204722
Age: postnatal week 6-8
Image: st96_255
Specimen Label: None
Detected: false
Specimen Num: 6
GXD Expression    
Probe: MGI:1204720
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Absent
Sex: Pooled
Emaps: EMAPS:1778728
Stage: TS28
Assay Id: MGI:1204722
Age: postnatal week 6-8
Image: st96_255
Specimen Label: None
Detected: false
Specimen Num: 7
GXD Expression    
Probe: MGI:1204720
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Absent
Sex: Pooled
Emaps: EMAPS:1757728
Stage: TS28
Assay Id: MGI:1204722
Age: postnatal week 6-8
Image: st96_255
Specimen Label: None
Detected: false
Specimen Num: 8
GXD Expression    
Probe: MGI:1204720
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:3599828
Stage: TS28
Assay Id: MGI:1204722
Age: postnatal week 6-8
Image: st96_255
Specimen Label: None
Detected: true
Specimen Num: 9
GXD Expression    
Probe: MGI:1204720
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1619828
Stage: TS28
Assay Id: MGI:1204722
Age: postnatal week 6-8
Image: st96_255
Specimen Label: None
Detected: true
Specimen Num: 10
GXD Expression    
Probe: MGI:1204720
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Absent
Sex: Pooled
Emaps: EMAPS:3598828
Stage: TS28
Assay Id: MGI:1204722
Age: postnatal week 6-8
Image: st96_255
Specimen Label: None
Detected: false
Specimen Num: 11
GXD Expression    
Probe: MGI:1204720
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:1204722
Age: postnatal week 6-8
Image: st96_255
Specimen Label: None
Detected: true
Specimen Num: 12
GXD Expression    
Probe: MGI:1204720
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1672828
Stage: TS28
Assay Id: MGI:1204722
Age: postnatal week 6-8
Image: st96_255
Specimen Label: None
Detected: true
Specimen Num: 13
GXD Expression    
Probe: MGI:1204720
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Absent
Sex: Pooled
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:1204722
Age: postnatal week 6-8
Image: st96_255
Specimen Label: None
Detected: false
Specimen Num: 14
GXD Expression    
Probe: MGI:1204720
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Absent
Sex: Pooled
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:1204722
Age: postnatal week 6-8
Image: st96_255
Specimen Label: None
Detected: false
Specimen Num: 15
GXD Expression    
Probe: MGI:1204720
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Absent
Sex: Pooled
Emaps: EMAPS:1720228
Stage: TS28
Assay Id: MGI:1204722
Age: postnatal week 6-8
Image: st96_255
Specimen Label: None
Detected: false
Specimen Num: 16
GXD Expression    
Probe: MGI:1204720
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Absent
Sex: Pooled
Emaps: EMAPS:1750328
Stage: TS28
Assay Id: MGI:1204722
Age: postnatal week 6-8
Image: st96_255
Specimen Label: None
Detected: false
Specimen Num: 17
GXD Expression    
Probe: MGI:1204720
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:1204722
Age: postnatal week 6-8
Image: st96_255
Specimen Label: None
Detected: true
Specimen Num: 18
GXD Expression    
Probe: MGI:1204720
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1832128
Stage: TS28
Assay Id: MGI:1204722
Age: postnatal week 6-8
Image: st96_255
Specimen Label: None
Detected: true
Specimen Num: 19
GXD Expression    
Probe: MGI:1204720
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Absent
Sex: Pooled
Emaps: EMAPS:1842628
Stage: TS28
Assay Id: MGI:1204722
Age: postnatal week 6-8
Image: st96_255
Specimen Label: None
Detected: false
Specimen Num: 20
GXD Expression    
Probe: MGI:1204720
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Absent
Sex: Pooled
Emaps: EMAPS:1752528
Stage: TS28
Assay Id: MGI:1204722
Age: postnatal week 6-8
Image: st96_255
Specimen Label: None
Detected: false
Specimen Num: 21
GXD Expression    
Probe: MGI:1204720
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Absent
Sex: Pooled
Emaps: EMAPS:3511228
Stage: TS28
Assay Id: MGI:1204722
Age: postnatal week 6-8
Image: st96_255
Specimen Label: None
Detected: false
Specimen Num: 22