|  Help  |  About  |  Contact Us

Search our database by keyword

Examples

  • Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
  • Use OR to search for either of two terms (e.g. OR mus) or quotation marks to search for phrases (e.g. "dna binding").
  • Boolean search syntax is supported: e.g. Balb* for partial matches or mus AND NOT embryo to exclude a term

Search results 1 to 100 out of 341 for Dio2

<< First    < Previous  |  Next >    Last >>
0.039s
Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: chimpanzee
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: zebrafish
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: dog, domestic
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Gene
Type: gene
Organism: human
Publication
First Author: Bomer N
Year: 2016
Journal: PLoS One
Title: Aberrant Calreticulin Expression in Articular Cartilage of Dio2 Deficient Mice.
Volume: 11
Issue: 5
Pages: e0154999
Publication
First Author: Castagna MG
Year: 2017
Journal: J Clin Endocrinol Metab
Title: DIO2 Thr92Ala Reduces Deiodinase-2 Activity and Serum-T3 Levels in Thyroid-Deficient Patients.
Volume: 102
Issue: 5
Pages: 1623-1630
Publication
First Author: Carmody C
Year: 2019
Journal: Endocrinology
Title: A Global Loss of Dio2 Leads to Unexpected Changes in Function and Fiber Types of Slow Skeletal Muscle in Male Mice.
Volume: 160
Issue: 5
Pages: 1205-1222
Publication
First Author: Christoffolete MA
Year: 2004
Journal: Diabetes
Title: Mice with targeted disruption of the Dio2 gene have cold-induced overexpression of the uncoupling protein 1 gene but fail to increase brown adipose tissue lipogenesis and adaptive thermogenesis.
Volume: 53
Issue: 3
Pages: 577-84
Publication
First Author: Bomer N
Year: 2016
Journal: Ann Rheum Dis
Title: The effect of forced exercise on knee joints in Dio2(-/-) mice: type II iodothyronine deiodinase-deficient mice are less prone to develop OA-like cartilage damage upon excessive mechanical stress.
Volume: 75
Issue: 3
Pages: 571-7
Publication
First Author: Christoffolete MA
Year: 2007
Journal: Endocrinology
Title: Mice with impaired extrathyroidal thyroxine to 3,5,3'-triiodothyronine conversion maintain normal serum 3,5,3'-triiodothyronine concentrations.
Volume: 148
Issue: 3
Pages: 954-60
Publication
First Author: de Jesus LA
Year: 2001
Journal: J Clin Invest
Title: The type 2 iodothyronine deiodinase is essential for adaptive thermogenesis in brown adipose tissue.
Volume: 108
Issue: 9
Pages: 1379-85
Publication
First Author: Bárez-López S
Year: 2014
Journal: PLoS One
Title: Abnormal motor phenotype at adult stages in mice lacking type 2 deiodinase.
Volume: 9
Issue: 8
Pages: e103857
Publication
First Author: Marsili A
Year: 2011
Journal: PLoS One
Title: Mice with a targeted deletion of the type 2 deiodinase are insulin resistant and susceptible to diet induced obesity.
Volume: 6
Issue: 6
Pages: e20832
Publication
First Author: Bocco BM
Year: 2016
Journal: Endocrinology
Title: Type 2 Deiodinase Disruption in Astrocytes Results in Anxiety-Depressive-Like Behavior in Male Mice.
Volume: 157
Issue: 9
Pages: 3682-95
Publication
First Author: Sawant OB
Year: 2017
Journal: Cell Rep
Title: The Circadian Clock Gene Bmal1 Controls Thyroid Hormone-Mediated Spectral Identity and Cone Photoreceptor Function.
Volume: 21
Issue: 3
Pages: 692-706
Publication
First Author: Schneider MJ
Year: 2001
Journal: Mol Endocrinol
Title: Targeted disruption of the type 2 selenodeiodinase gene (DIO2) results in a phenotype of pituitary resistance to T4.
Volume: 15
Issue: 12
Pages: 2137-48
Publication
First Author: Waung JA
Year: 2015
Journal: Thyroid
Title: Adult mice lacking the type 2 iodothyronine deiodinase have increased subchondral bone but normal articular cartilage.
Volume: 25
Issue: 3
Pages: 269-77
Publication
First Author: Wang YY
Year: 2010
Journal: Cardiovasc Res
Title: Up-regulation of type 2 iodothyronine deiodinase in dilated cardiomyopathy.
Volume: 87
Issue: 4
Pages: 636-46
Publication
First Author: Ng L
Year: 2017
Journal: Endocrinology
Title: Deletion of the Thyroid Hormone-Activating Type 2 Deiodinase Rescues Cone Photoreceptor Degeneration but Not Deafness in Mice Lacking Type 3 Deiodinase.
Volume: 158
Issue: 6
Pages: 1999-2010
Publication
First Author: Morte B
Year: 2010
Journal: Endocrinology
Title: Thyroid hormone-regulated mouse cerebral cortex genes are differentially dependent on the source of the hormone: a study in monocarboxylate transporter-8- and deiodinase-2-deficient mice.
Volume: 151
Issue: 5
Pages: 2381-7
Publication
First Author: Nascimento BPP
Year: 2018
Journal: Endocrinology
Title: Induction of Type 2 Iodothyronine Deiodinase After Status Epilepticus Modifies Hippocampal Gene Expression in Male Mice.
Volume: 159
Issue: 8
Pages: 3090-3104
Publication
First Author: Ferdous A
Year: 2020
Journal: Nat Commun
Title: FoxO1-Dio2 signaling axis governs cardiomyocyte thyroid hormone metabolism and hypertrophic growth.
Volume: 11
Issue: 1
Pages: 2551
Publication
First Author: Werneck-de-Castro JP
Year: 2015
Journal: Endocrinology
Title: Thyroid Hormone Signaling in Male Mouse Skeletal Muscle Is Largely Independent of D2 in Myocytes.
Volume: 156
Issue: 10
Pages: 3842-52
Publication
First Author: Kojima Y
Year: 2019
Journal: Cancer Sci
Title: Stromal iodothyronine deiodinase 2 (DIO2) promotes the growth of intestinal tumors in ApcΔ716 mutant mice.
Volume: 110
Issue: 8
Pages: 2520-2528
Publication    
First Author: Yang F
Year: 2018
Journal: FASEB J
Title: Deficiency of type 2 iodothyronine deiodinase reduces necroptosis activity and oxidative stress responses in retinas of Leber congenital amaurosis model mice.
Pages: fj201800484RR
Publication
First Author: Butterfield NC
Year: 2021
Journal: Nat Commun
Title: Accelerating functional gene discovery in osteoarthritis.
Volume: 12
Issue: 1
Pages: 467
Publication
First Author: Ignacio DL
Year: 2017
Journal: Thyroid
Title: Early Developmental Disruption of Type 2 Deiodinase Pathway in Mouse Skeletal Muscle Does Not Impair Muscle Function.
Volume: 27
Issue: 4
Pages: 577-586
Publication
First Author: Hall JA
Year: 2010
Journal: Endocrinology
Title: Absence of thyroid hormone activation during development underlies a permanent defect in adaptive thermogenesis.
Volume: 151
Issue: 9
Pages: 4573-82
Publication
First Author: Bocco BM
Year: 2016
Journal: J Physiol
Title: Thyroid hormone activation by type 2 deiodinase mediates exercise-induced peroxisome proliferator-activated receptor-γ coactivator-1α expression in skeletal muscle.
Volume: 594
Issue: 18
Pages: 5255-69
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Davey JC
Year: 1999
Journal: Endocrinology
Title: Cloning of a 5.8 kb cDNA for a mouse type 2 deiodinase.
Volume: 140
Issue: 2
Pages: 1022-5
Publication
First Author: Campos-Barros A
Year: 2000
Journal: Proc Natl Acad Sci U S A
Title: Type 2 iodothyronine deiodinase expression in the cochlea before the onset of hearing.
Volume: 97
Issue: 3
Pages: 1287-92
Publication
First Author: Song S
Year: 2000
Journal: Mol Cell Endocrinol
Title: Isolation and characterization of the 5'-upstream and untranslated regions of the mouse type II iodothyronine deiodinase gene.
Volume: 165
Issue: 1-2
Pages: 189-98
Publication
First Author: Ramadan W
Year: 2011
Journal: Endocrinology
Title: Type-2 iodothyronine 5'deiodinase in skeletal muscle of C57BL/6 mice. I. Identity, subcellular localization, and characterization.
Volume: 152
Issue: 8
Pages: 3082-92
Publication
First Author: Galton VA
Year: 2007
Journal: Endocrinology
Title: Thyroid hormone homeostasis and action in the type 2 deiodinase-deficient rodent brain during development.
Volume: 148
Issue: 7
Pages: 3080-8
Publication
First Author: Castillo M
Year: 2011
Journal: Diabetes
Title: Disruption of thyroid hormone activation in type 2 deiodinase knockout mice causes obesity with glucose intolerance and liver steatosis only at thermoneutrality.
Volume: 60
Issue: 4
Pages: 1082-9
Publication
First Author: da-Silva WS
Year: 2011
Journal: FEBS Lett
Title: The chemical chaperones tauroursodeoxycholic and 4-phenylbutyric acid accelerate thyroid hormone activation and energy expenditure.
Volume: 585
Issue: 3
Pages: 539-44
Publication
First Author: Marsili A
Year: 2011
Journal: Am J Physiol Endocrinol Metab
Title: Type II iodothyronine deiodinase provides intracellular 3,5,3'-triiodothyronine to normal and regenerating mouse skeletal muscle.
Volume: 301
Issue: 5
Pages: E818-24
Publication
First Author: Ng L
Year: 2004
Journal: Proc Natl Acad Sci U S A
Title: Hearing loss and retarded cochlear development in mice lacking type 2 iodothyronine deiodinase.
Volume: 101
Issue: 10
Pages: 3474-9
Publication
First Author: Jo S
Year: 2019
Journal: J Clin Invest
Title: Type 2 deiodinase polymorphism causes ER stress and hypothyroidism in the brain.
Volume: 129
Issue: 1
Pages: 230-245
Publication
First Author: Luongo C
Year: 2015
Journal: Endocrinology
Title: The selective loss of the type 2 iodothyronine deiodinase in mouse thyrotrophs increases basal TSH but blunts the thyrotropin response to hypothyroidism.
Volume: 156
Issue: 2
Pages: 745-54
Publication
First Author: Fonseca TL
Year: 2019
Journal: Alcohol Clin Exp Res
Title: Hepatic Inactivation of the Type 2 Deiodinase Confers Resistance to Alcoholic Liver Steatosis.
Volume: 43
Issue: 7
Pages: 1376-1383
GXD Expression      
Probe: MGI:4867415
Assay Type: RT-PCR
Annotation Date: 2011-01-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1920924
Stage: TS24
Assay Id: MGI:4867457
Age: embryonic day 16.5
Specimen Label: E16.5
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:4867415
Assay Type: RT-PCR
Annotation Date: 2011-01-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1920925
Stage: TS25
Assay Id: MGI:4867457
Age: embryonic day 17.5
Specimen Label: E17.5
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:4867415
Assay Type: RT-PCR
Annotation Date: 2011-01-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1920926
Stage: TS26
Assay Id: MGI:4867457
Age: embryonic day 18.5
Specimen Label: E18.5
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:4867415
Assay Type: RT-PCR
Annotation Date: 2011-01-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1920924
Stage: TS24
Assay Id: MGI:4867457
Age: embryonic day 16.5
Specimen Label: E16.5
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:4867415
Assay Type: RT-PCR
Annotation Date: 2011-01-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1920925
Stage: TS25
Assay Id: MGI:4867457
Age: embryonic day 17.5
Specimen Label: E17.5
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:4867415
Assay Type: RT-PCR
Annotation Date: 2011-01-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1920926
Stage: TS26
Assay Id: MGI:4867457
Age: embryonic day 18.5
Specimen Label: E18.5
Detected: true
Specimen Num: 6
GXD Expression      
Probe: MGI:4867415
Assay Type: RT-PCR
Annotation Date: 2011-01-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1920924
Stage: TS24
Assay Id: MGI:4867457
Age: embryonic day 16.5
Specimen Label: E16.5
Detected: true
Specimen Num: 7
GXD Expression      
Probe: MGI:4867415
Assay Type: RT-PCR
Annotation Date: 2011-01-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1920925
Stage: TS25
Assay Id: MGI:4867457
Age: embryonic day 17.5
Specimen Label: E17.5
Detected: true
Specimen Num: 8
GXD Expression      
Probe: MGI:4867415
Assay Type: RT-PCR
Annotation Date: 2011-01-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1920926
Stage: TS26
Assay Id: MGI:4867457
Age: embryonic day 18.5
Specimen Label: E18.5
Detected: true
Specimen Num: 9
GXD Expression      
Probe: MGI:4867415
Assay Type: RT-PCR
Annotation Date: 2011-01-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1920924
Stage: TS24
Assay Id: MGI:4880874
Age: embryonic day 16.5
Specimen Label: E16.5
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:4867415
Assay Type: RT-PCR
Annotation Date: 2011-01-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1920925
Stage: TS25
Assay Id: MGI:4880874
Age: embryonic day 17.5
Specimen Label: E17.5
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:4867415
Assay Type: RT-PCR
Annotation Date: 2011-01-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1920926
Stage: TS26
Assay Id: MGI:4880874
Age: embryonic day 18.5
Specimen Label: E18.5
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:5308762
Assay Type: RT-PCR
Annotation Date: 2012-03-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1759726
Stage: TS26
Assay Id: MGI:5311404
Age: embryonic day 18.0
Specimen Label: E18
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:5308762
Assay Type: RT-PCR
Annotation Date: 2012-03-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1759727
Stage: TS27
Assay Id: MGI:5311404
Age: postnatal day 3
Specimen Label: P3
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:5308762
Assay Type: RT-PCR
Annotation Date: 2012-03-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1759728
Stage: TS28
Assay Id: MGI:5311404
Age: postnatal day 5
Specimen Label: P5
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:5308762
Assay Type: RT-PCR
Annotation Date: 2012-03-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1759728
Stage: TS28
Assay Id: MGI:5311404
Age: postnatal day 7
Specimen Label: P7
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:5308762
Assay Type: RT-PCR
Annotation Date: 2012-03-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1759728
Stage: TS28
Assay Id: MGI:5311404
Age: postnatal day 15
Specimen Label: P15
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:5308739
Assay Type: Northern blot
Annotation Date: 2016-09-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1759725
Stage: TS25
Assay Id: MGI:5792865
Age: embryonic day 17.0
Specimen Label: E17
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:5308739
Assay Type: Northern blot
Annotation Date: 2016-09-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1759727
Stage: TS27
Assay Id: MGI:5792865
Age: postnatal day 1
Specimen Label: P1
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:5308739
Assay Type: Northern blot
Annotation Date: 2016-09-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1759728
Stage: TS28
Assay Id: MGI:5792865
Age: postnatal day 8
Specimen Label: P8
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:5308739
Assay Type: Northern blot
Annotation Date: 2016-09-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1759728
Stage: TS28
Assay Id: MGI:5792865
Age: postnatal day 13
Specimen Label: P13
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:5308739
Assay Type: Northern blot
Annotation Date: 2016-09-22
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1619828
Stage: TS28
Assay Id: MGI:5792865
Age: postnatal adult
Specimen Label: eye
Detected: false
Specimen Num: 5
GXD Expression      
Probe: MGI:5308739
Assay Type: Northern blot
Annotation Date: 2016-09-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:5792865
Age: postnatal adult
Specimen Label: brain
Detected: true
Specimen Num: 6
GXD Expression      
Probe: MGI:5308739
Assay Type: Northern blot
Annotation Date: 2016-09-22
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:5792865
Age: postnatal adult
Specimen Label: liver
Detected: false
Specimen Num: 7
GXD Expression      
Probe: MGI:6114626
Assay Type: RT-PCR
Annotation Date: 2018-02-06
Strength: Present
Sex: Male
Emaps: EMAPS:1706828
Stage: TS28
Assay Id: MGI:6114696
Age: postnatal month 2
Specimen Label: Thyr-TRB<+/+>
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:6114626
Assay Type: RT-PCR
Annotation Date: 2018-02-06
Strength: Present
Sex: Male
Emaps: EMAPS:1706828
Stage: TS28
Assay Id: MGI:6114696
Age: postnatal month 2
Specimen Label: Thyr-TRB<+/->
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:6114626
Assay Type: RT-PCR
Annotation Date: 2018-02-06
Strength: Present
Sex: Male
Emaps: EMAPS:1706828
Stage: TS28
Assay Id: MGI:6114696
Age: postnatal month 2
Specimen Label: Thyr-TRB<-/->
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:6305307
Assay Type: RT-PCR
Annotation Date: 2019-05-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1920928
Stage: TS28
Assay Id: MGI:6305400
Age: postnatal adult
Specimen Label: RT f/f
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:6305307
Assay Type: RT-PCR
Annotation Date: 2019-05-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1920928
Stage: TS28
Assay Id: MGI:6305400
Age: postnatal adult
Specimen Label: RT cKO
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:6842397
Assay Type: RT-PCR
Annotation Date: 2021-12-31
Strength: Present
Sex: Pooled
Emaps: EMAPS:1689421
Stage: TS21
Assay Id: MGI:6842494
Age: embryonic day 13.5
Image: 1
Specimen Label: E13.5
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:6842397
Assay Type: RT-PCR
Annotation Date: 2021-12-31
Strength: Present
Sex: Pooled
Emaps: EMAPS:1689426
Stage: TS26
Assay Id: MGI:6842494
Age: embryonic day 18.5
Image: 1
Specimen Label: E18.5
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:6842397
Assay Type: RT-PCR
Annotation Date: 2021-12-31
Strength: Present
Sex: Pooled
Emaps: EMAPS:1689426
Stage: TS26
Assay Id: MGI:6842455
Age: embryonic day 18.5
Image: 4
Specimen Label: +/+
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:6842397
Assay Type: RT-PCR
Annotation Date: 2021-12-31
Strength: Present
Sex: Pooled
Emaps: EMAPS:1689426
Stage: TS26
Assay Id: MGI:6842455
Age: embryonic day 18.5
Image: 4
Specimen Label: -/-
Detected: true
Specimen Num: 2