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Search results 1 to 100 out of 532 for Disc1

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Type Details Score
Gene
27185 | DISC1
Type: gene
Organism: human
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Gene
719086 | DISC1
Type: gene
Organism: macaque, rhesus
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Gene
613555 | DISC1
Type: gene
Organism: cattle
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Gene
407621 | disc1
Type: gene
Organism: zebrafish
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Gene
307940 | Disc1
Type: gene
Organism: rat
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Gene
742093 | DISC1
Type: gene
Organism: chimpanzee
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Gene
488970 | DISC1
Type: gene
Organism: dog, domestic
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Gene
100859633 | DISC1
Type: gene
Organism: chicken
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Protein Domain
IPR026081 | DISC1
Type: Family
Description: Disrupted-In-Schizophrenia 1 (DISC1) was identified as a novel gene disrupted by a (1;11)(q42.1;q14.3) translocation segregating with schizophrenia, bipolar disorder and other major mental illnesses in a Scottish family [, ]. Human DISC1 is multifunctional with several interacting proteins, including components of the dynein motor protein complex, such as nuclear distribution element-like (NDEL1/NUDEL) and lissencephaly 1 protein (LIS1). DISC1 is also required for regulation of microtubule dynamics, neurite outgrowth and neuronal migration in vivo [].
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Protein Coding Gene
MGI:2447658 | Disc1
Type: protein_coding_gene
Organism: mouse, laboratory
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Gene
101929222 | DISC1FP1
Type: gene
Organism: human
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Gene
104472714 | DISC1-IT1
Type: gene
Organism: human
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Publication
35563598 | J:346810
 
First Author: Takahashi Y
Year: 2022
Journal: Int J Mol Sci
Title: Polysialylation in a DISC1 Mutant Mouse.
Volume: 23
Issue: 9
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Publication
17481393 | J:120634
First Author: Clapcote SJ
Year: 2007
Journal: Neuron
Title: Behavioral phenotypes of Disc1 missense mutations in mice.
Volume: 54
Issue: 3
Pages: 387-402
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Publication
26768401 | J:232443
 
First Author: Tomoda T
Year: 2016
Journal: Neuroscience
Title: Utility and validity of DISC1 mouse models in biological psychiatry.
Volume: 321
Pages: 99-107
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Publication
25272038 | J:223479
First Author: Chandran JS
Year: 2014
Journal: PLoS One
Title: Disc1 variation leads to specific alterations in adult neurogenesis.
Volume: 9
Issue: 10
Pages: e108088
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Publication
21376063 | J:183587
First Author: Lipina TV
Year: 2012
Journal: Neuropharmacology
Title: Synergistic interactions between PDE4B and GSK-3: DISC1 mutant mice.
Volume: 62
Issue: 3
Pages: 1252-62
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Protein
Q811T9
Organism: Mus musculus/domesticus
Length: 852  
Fragment?: false
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Protein
Z4YLG9
Organism: Mus musculus/domesticus
Length: 789  
Fragment?: false
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Protein
D3YYC9
Organism: Mus musculus/domesticus
Length: 852  
Fragment?: false
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Publication
11443544 | -
First Author: Blackwood DH
Year: 2001
Journal: Am J Hum Genet
Title: Schizophrenia and affective disorders--cosegregation with a translocation at chromosome 1q42 that directly disrupts brain-expressed genes: clinical and P300 findings in a family.
Volume: 69
Issue: 2
Pages: 428-33
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Publication
10814723 | -
First Author: Millar JK
Year: 2000
Journal: Hum Mol Genet
Title: Disruption of two novel genes by a translocation co-segregating with schizophrenia.
Volume: 9
Issue: 9
Pages: 1415-23
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Publication
17035248 | -
First Author: Kamiya A
Year: 2006
Journal: Hum Mol Genet
Title: DISC1-NDEL1/NUDEL protein interaction, an essential component for neurite outgrowth, is modulated by genetic variations of DISC1.
Volume: 15
Issue: 22
Pages: 3313-23
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Publication
25487992 | J:223259
 
First Author: Arime Y
Year: 2014
Journal: Behav Brain Funct
Title: Effects of background mutations and single nucleotide polymorphisms (SNPs) on the Disc1 L100P behavioral phenotype associated with schizophrenia in mice.
Volume: 10
Pages: 45
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Publication
21368031 | J:170676
First Author: Lee FH
Year: 2011
Journal: J Neurosci
Title: Disc1 point mutations in mice affect development of the cerebral cortex.
Volume: 31
Issue: 9
Pages: 3197-206
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Publication
23637159 | J:197023
First Author: Lipina TV
Year: 2013
Journal: J Neurosci
Title: Maternal immune activation during gestation interacts with Disc1 point mutation to exacerbate schizophrenia-related behaviors in mice.
Volume: 33
Issue: 18
Pages: 7654-66
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Publication
22659396 | J:190472
First Author: Haque FN
Year: 2012
Journal: Behav Brain Res
Title: Social defeat interacts with Disc1 mutations in the mouse to affect behavior.
Volume: 233
Issue: 2
Pages: 337-44
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Publication
29212023 | J:254274
First Author: Park SJ
Year: 2017
Journal: Cell Rep
Title: DISC1 Modulates Neuronal Stress Responses by Gate-Keeping ER-Mitochondria Ca2+ Transfer through the MAM.
Volume: 21
Issue: 10
Pages: 2748-2759
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Publication
26656849 | J:228295
 
First Author: Seshadri S
Year: 2015
Journal: Nat Commun
Title: Interneuronal DISC1 regulates NRG1-ErbB4 signalling and excitatory-inhibitory synapse formation in the mature cortex.
Volume: 6
Pages: 10118
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Publication
22099458 | J:178949
First Author: Singh KK
Year: 2011
Journal: Neuron
Title: Common DISC1 polymorphisms disrupt Wnt/GSK3β signaling and brain development.
Volume: 72
Issue: 4
Pages: 545-58
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Publication
25224257 | J:325317
First Author: Shahani N
Year: 2015
Journal: Mol Psychiatry
Title: DISC1 regulates trafficking and processing of APP and Aβ generation.
Volume: 20
Issue: 7
Pages: 874-9
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Publication
28631721 | J:272767
First Author: Terrillion CE
Year: 2017
Journal: Neuropsychopharmacology
Title: DISC1 in Astrocytes Influences Adult Neurogenesis and Hippocampus-Dependent Behaviors in Mice.
Volume: 42
Issue: 11
Pages: 2242-2251
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Publication
32803234 | J:296584
First Author: Shevelkin AV
Year: 2020
Journal: Hum Mol Genet
Title: Astrocyte DISC1 contributes to cognitive function in a brain region-dependent manner.
Volume: 29
Issue: 17
Pages: 2936-2950
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Publication
26093170 | J:227433
 
First Author: Ballinger MD
Year: 2015
Journal: Neurobiol Dis
Title: Adolescent cannabis exposure interacts with mutant DISC1 to produce impaired adult emotional memory.
Volume: 82
Pages: 176-184
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Publication
19716847 | J:153989
First Author: Ibi D
Year: 2010
Journal: Behav Brain Res
Title: Combined effect of neonatal immune activation and mutant DISC1 on phenotypic changes in adulthood.
Volume: 206
Issue: 1
Pages: 32-7
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Publication
20531939 | J:220450
First Author: Marley A
Year: 2010
Journal: PLoS One
Title: DISC1 regulates primary cilia that display specific dopamine receptors.
Volume: 5
Issue: 5
Pages: e10902
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Publication
21130225 | J:281307
First Author: Abazyan B
Year: 2010
Journal: Biol Psychiatry
Title: Prenatal interaction of mutant DISC1 and immune activation produces adult psychopathology.
Volume: 68
Issue: 12
Pages: 1172-81
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Publication
28392471 | J:258973
 
First Author: Shevelkin AV
Year: 2017
Journal: Neurobiol Dis
Title: Expression of mutant DISC1 in Purkinje cells increases their spontaneous activity and impairs cognitive and social behaviors in mice.
Volume: 103
Pages: 144-153
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Publication
19502360 | J:151421
First Author: Meyer KD
Year: 2009
Journal: Hum Mol Genet
Title: Disc1 regulates granule cell migration in the developing hippocampus.
Volume: 18
Issue: 17
Pages: 3286-97
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Publication
27346367 | J:235949
First Author: Ren J
Year: 2016
Journal: Brain Res
Title: Interaction between DISC1 and CHL1 in regulation of neurite outgrowth.
Volume: 1648
Issue: Pt A
Pages: 290-297
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Publication
16484369 | J:107244
First Author: Koike H
Year: 2006
Journal: Proc Natl Acad Sci U S A
Title: Disc1 is mutated in the 129S6/SvEv strain and modulates working memory in mice.
Volume: 103
Issue: 10
Pages: 3693-7
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Publication
30116177 | J:276327
 
First Author: Li N
Year: 2018
Journal: Front Cell Neurosci
Title: Adolescent Isolation Interacts With DISC1 Point Mutation to Impair Adult Social Memory and Synaptic Functions in the Hippocampus.
Volume: 12
Pages: 238
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Publication
12504857 | J:80804
First Author: Ma L
Year: 2002
Journal: Genomics
Title: Cloning and characterization of Disc1, the mouse ortholog of DISC1 (Disrupted-in-Schizophrenia 1).
Volume: 80
Issue: 6
Pages: 662-72
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Publication
34815409 | J:317943
First Author: Xu X
Year: 2021
Journal: Nat Commun
Title: Developmental decrease of entorhinal-hippocampal communication in immune-challenged DISC1 knockdown mice.
Volume: 12
Issue: 1
Pages: 6810
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Publication
23314019 | J:194985
First Author: Jaaro-Peled H
Year: 2013
Journal: Hum Mol Genet
Title: Subcortical dopaminergic deficits in a DISC1 mutant model: a study in direct reference to human molecular brain imaging.
Volume: 22
Issue: 8
Pages: 1574-80
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Publication
28263187 | J:243373
First Author: Tanaka M
Year: 2017
Journal: J Clin Invest
Title: Aggregation of scaffolding protein DISC1 dysregulates phosphodiesterase 4 in Huntington's disease.
Volume: 127
Issue: 4
Pages: 1438-1450
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Publication
28981898 | J:273093
First Author: Katsel P
Year: 2018
Journal: Schizophr Bull
Title: Overexpression of Truncated Human DISC1 Induces Appearance of Hindbrain Oligodendroglia in the Forebrain During Development.
Volume: 44
Issue: 3
Pages: 515-524
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Publication
16751659 | J:111837
First Author: Clapcote SJ
Year: 2006
Journal: Genetics
Title: Deletion polymorphism of Disc1 is common to all 129 mouse substrains: implications for gene-targeting studies of brain function.
Volume: 173
Issue: 4
Pages: 2407-10
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Publication
30391323 | J:273059
 
First Author: Jacobi AA
Year: 2019
Journal: Neurosci Lett
Title: Neuronal serine racemase associates with Disrupted-In-Schizophrenia-1 and DISC1 agglomerates: Implications for schizophrenia.
Volume: 692
Pages: 107-114
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Publication
20624590 | J:163156
First Author: Singh KK
Year: 2010
Journal: Neuron
Title: Dixdc1 is a critical regulator of DISC1 and embryonic cortical development.
Volume: 67
Issue: 1
Pages: 33-48
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GXD Expression
GXD Expression
     
Probe: MGI:6171213
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689419
Stage: TS19
Assay Id: MGI:6190114
Age: embryonic day 11.5
Specimen Label: Table S2 - E11.5 - Disc1
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:6171213
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689421
Stage: TS21
Assay Id: MGI:6190114
Age: embryonic day 13.5
Specimen Label: Table S2 - E13.5 - Disc1
Detected: false
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:6171213
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Male
Emaps: EMAPS:1689426
Stage: TS26
Assay Id: MGI:6190114
Age: embryonic day 18.5
Specimen Label: Table S2 - E18.5 - Disc1
Detected: false
Specimen Num: 4
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GXD Expression
GXD Expression
     
Probe: MGI:6171213
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Male
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:6190114
Age: postnatal day 4
Specimen Label: Table S2 - P4 - Disc1
Detected: false
Specimen Num: 5
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GXD Expression
GXD Expression
     
Probe: MGI:6171213
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Male
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:6190114
Age: postnatal day 28
Specimen Label: Table S2 - P28 - Disc1
Detected: false
Specimen Num: 7
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GXD Expression
GXD Expression
     
Probe: MGI:6171213
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Male
Emaps: EMAPS:1689424
Stage: TS24
Assay Id: MGI:6190114
Age: embryonic day 15.5
Specimen Label: Table S2 - E15.5 - Disc1
Detected: false
Specimen Num: 3
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GXD Expression
GXD Expression
     
Probe: MGI:6171213
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Male
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:6190114
Age: postnatal day 14
Specimen Label: Table S2 - P14 - Disc1
Detected: false
Specimen Num: 6
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Publication
26212236 | J:227031
First Author: Rodríguez-Seoane C
Year: 2015
Journal: J Neurochem
Title: DISC1 regulates expression of the neurotrophin VGF through the PI3K/AKT/CREB pathway.
Volume: 135
Issue: 3
Pages: 598-605
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Publication
23396153 | J:203645
 
First Author: Lepagnol-Bestel AM
Year: 2013
Journal: Mol Cell Neurosci
Title: A Disc1 mutation differentially affects neurites and spines in hippocampal and cortical neurons.
Volume: 54
Pages: 84-92
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Publication
33658519 | J:304928
First Author: Kim NS
Year: 2021
Journal: Nat Commun
Title: Pharmacological rescue in patient iPSC and mouse models with a rare DISC1 mutation.
Volume: 12
Issue: 1
Pages: 1398
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Publication
23439118 | J:197828
First Author: Zhou M
Year: 2013
Journal: Neuron
Title: mTOR Inhibition ameliorates cognitive and affective deficits caused by Disc1 knockdown in adult-born dentate granule neurons.
Volume: 77
Issue: 4
Pages: 647-54
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Publication
22099459 | J:178948
First Author: Kang E
Year: 2011
Journal: Neuron
Title: Interaction between FEZ1 and DISC1 in regulation of neuronal development and risk for schizophrenia.
Volume: 72
Issue: 4
Pages: 559-71
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Publication
18620078 | J:138305
First Author: Meyer KD
Year: 2008
Journal: Gene Expr Patterns
Title: Immunohistochemical analysis of Disc1 expression in the developing and adult hippocampus.
Volume: 8
Issue: 7-8
Pages: 494-501
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Publication
31721208 | J:289635
First Author: Baskaran R
Year: 2020
Journal: J Comp Neurol
Title: Characterization of striatal phenotypes in heterozygous Disc1 mutant mice, a model of haploinsufficiency.
Volume: 528
Issue: 7
Pages: 1157-1172
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Publication
22049344 | J:180193
First Author: Kvajo M
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Altered axonal targeting and short-term plasticity in the hippocampus of Disc1 mutant mice.
Volume: 108
Issue: 49
Pages: E1349-58
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Publication
26728762 | J:229661
 
First Author: Dachtler J
Year: 2016
Journal: Sci Rep
Title: Missense mutation in DISC1 C-terminal coiled-coil has GSK3β signaling and sex-dependent behavioral effects in mice.
Volume: 6
Pages: 18748
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Publication
30561706 | J:314277
First Author: Kakuda K
Year: 2019
Journal: J Biochem
Title: A DISC1 point mutation promotes oligomerization and impairs information processing in a mouse model of schizophrenia.
Volume: 165
Issue: 4
Pages: 369-378
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Publication
26497623 | J:231838
 
First Author: Hayashi Y
Year: 2016
Journal: Neurosci Res
Title: Impaired hippocampal activity at the goal zone on the place preference task in a DISC1 mouse model.
Volume: 106
Pages: 70-3
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Publication
21739582 | J:175873
First Author: Osbun N
Year: 2011
Journal: Am J Med Genet A
Title: Genetic and functional analyses identify DISC1 as a novel callosal agenesis candidate gene.
Volume: 155A
Issue: 8
Pages: 1865-76
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Publication
19778506 | J:154919
First Author: Kim JY
Year: 2009
Journal: Neuron
Title: DISC1 regulates new neuron development in the adult brain via modulation of AKT-mTOR signaling through KIAA1212.
Volume: 63
Issue: 6
Pages: 761-73
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Publication
27287808 | J:235739
First Author: Wang S
Year: 2016
Journal: Development
Title: DISC1 regulates astrogenesis in the embryonic brain via modulation of RAS/MEK/ERK signaling through RASSF7.
Volume: 143
Issue: 15
Pages: 2732-40
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Publication
21436042 | J:171213
First Author: Ramsey AJ
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Impaired NMDA receptor transmission alters striatal synapses and DISC1 protein in an age-dependent manner.
Volume: 108
Issue: 14
Pages: 5795-800
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Publication
23563120 | J:195189
First Author: Ritchie DJ
Year: 2013
Journal: Lab Anim
Title: Disc1 deletion is present in Swiss-derived inbred mouse strains: implications for transgenic studies of learning and memory.
Volume: 47
Issue: 3
Pages: 162-7
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Publication
25126062 | J:250220
 
First Author: Gómez-Sintes R
Year: 2014
Journal: Front Behav Neurosci
Title: Mice with a naturally occurring DISC1 mutation display a broad spectrum of behaviors associated to psychiatric disorders.
Volume: 8
Pages: 253
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Publication
33037815 | J:300180
First Author: Xu X
Year: 2021
Journal: Cereb Cortex
Title: Knock-Down of Hippocampal DISC1 in Immune-Challenged Mice Impairs the Prefrontal-Hippocampal Coupling and the Cognitive Performance Throughout Development.
Volume: 31
Issue: 2
Pages: 1240-1258
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Publication
21903668 | J:177560
First Author: Kuroda K
Year: 2011
Journal: Hum Mol Genet
Title: Behavioral alterations associated with targeted disruption of exons 2 and 3 of the Disc1 gene in the mouse.
Volume: 20
Issue: 23
Pages: 4666-83
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Publication
27979975 | J:239308
First Author: Chen CY
Year: 2017
Journal: EMBO Rep
Title: TLR3 downregulates expression of schizophrenia gene Disc1 via MYD88 to control neuronal morphology.
Volume: 18
Issue: 1
Pages: 169-183
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Publication
30617212 | J:272036
First Author: Xu X
Year: 2019
Journal: J Neurosci
Title: Transient Knock-Down of Prefrontal DISC1 in Immune-Challenged Mice Causes Abnormal Long-Range Coupling and Cognitive Dysfunction throughout Development.
Volume: 39
Issue: 7
Pages: 1222-1235
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Publication
18458327 | J:134884
First Author: Kvajo M
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: A mutation in mouse Disc1 that models a schizophrenia risk allele leads to specific alterations in neuronal architecture and cognition.
Volume: 105
Issue: 19
Pages: 7076-81
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Publication
18762586 | J:220804
First Author: Kamiya A
Year: 2008
Journal: Arch Gen Psychiatry
Title: Recruitment of PCM1 to the centrosome by the cooperative action of DISC1 and BBS4: a candidate for psychiatric illnesses.
Volume: 65
Issue: 9
Pages: 996-1006
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Publication
20807500 | J:165586
First Author: Kubo K
Year: 2010
Journal: Biochem Biophys Res Commun
Title: Migration defects by DISC1 knockdown in C57BL/6, 129X1/SvJ, and ICR strains via in utero gene transfer and virus-mediated RNAi.
Volume: 400
Issue: 4
Pages: 631-7
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Publication
25698733 | J:219862
First Author: Okamoto M
Year: 2015
Journal: J Neurosci
Title: DBZ regulates cortical cell positioning and neurite development by sustaining the anterograde transport of Lis1 and DISC1 through control of Ndel1 dual-phosphorylation.
Volume: 35
Issue: 7
Pages: 2942-58
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Publication
27729083 | J:250086
First Author: Cui L
Year: 2016
Journal: Mol Brain
Title: Disrupted-in-schizophrenia1 (DISC1) L100P mutation alters synaptic transmission and plasticity in the hippocampus and causes recognition memory deficits.
Volume: 9
Issue: 1
Pages: 89
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Publication
20618446 | J:178211
First Author: Lipina TV
Year: 2010
Journal: Genes Brain Behav
Title: Enhanced dopamine function in DISC1-L100P mutant mice: implications for schizophrenia.
Volume: 9
Issue: 7
Pages: 777-89
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Publication
26756905 | J:250088
 
First Author: Tropea D
Year: 2016
Journal: Transl Psychiatry
Title: Disrupted in schizophrenia 1 (DISC1) L100P mutants have impaired activity-dependent plasticity in vivo and in vitro.
Volume: 6
Pages: e712
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Publication
22388794 | J:305135
First Author: Walsh J
Year: 2012
Journal: J Neurosci Res
Title: Disruption of exploratory and habituation behavior in mice with mutation of DISC1: an ethologically based analysis.
Volume: 90
Issue: 7
Pages: 1445-53
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Publication
32029441 | J:288238
 
First Author: Delevich K
Year: 2020
Journal: eNeuro
Title: Parvalbumin Interneuron Dysfunction in a Thalamo-Prefrontal Cortical Circuit in Disc1 Locus Impairment Mice.
Volume: 7
Issue: 2
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Publication
23272119 | J:195647
First Author: Lipina TV
Year: 2012
Journal: PLoS One
Title: Prophylactic valproic acid treatment prevents schizophrenia-related behaviour in Disc1-L100P mutant mice.
Volume: 7
Issue: 12
Pages: e51562
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Publication
20956536 | J:167582
First Author: Fukuda T
Year: 2010
Journal: J Biol Chem
Title: CAMDI, a novel disrupted in schizophrenia 1 (DISC1)-binding protein, is required for radial migration.
Volume: 285
Issue: 52
Pages: 40554-61
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Publication
20561508 | J:163335
 
First Author: Walsh J
Year: 2010
Journal: Brain Res
Title: Disruption of thermal nociceptive behaviour in mice mutant for the schizophrenia-associated genes NRG1, COMT and DISC1.
Volume: 1348
Pages: 114-9
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Publication
25433637 | J:223078
First Author: Su P
Year: 2014
Journal: Neuron
Title: A dopamine D2 receptor-DISC1 protein complex may contribute to antipsychotic-like effects.
Volume: 84
Issue: 6
Pages: 1302-16
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Publication
27613806 | J:258805
First Author: O'Tuathaigh CM
Year: 2017
Journal: Schizophr Bull
Title: Epistatic and Independent Effects on Schizophrenia-Related Phenotypes Following Co-disruption of the Risk Factors Neuregulin-1 × DISC1.
Volume: 43
Issue: 1
Pages: 214-225
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Publication
27916686 | J:250447
 
First Author: Desbonnet L
Year: 2017
Journal: Behav Brain Res
Title: Altered cytokine profile, pain sensitivity, and stress responsivity in mice with co-disruption of the developmental genes Neuregulin-1×DISC1.
Volume: 320
Pages: 113-118
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Publication
27244370 | J:249072
First Author: Borkowska M
Year: 2016
Journal: PLoS One
Title: Altered Disrupted-in-Schizophrenia-1 Function Affects the Development of Cortical Parvalbumin Interneurons by an Indirect Mechanism.
Volume: 11
Issue: 5
Pages: e0156082
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Publication
- | J:118317
     
First Author: Clapcote SJ
Year: 2007
Journal: MGI Direct Data Submission
Title: Inbred mouse strains 101/RI, BTBR T tf/J and LP/J have a deletion in Disc1
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Publication
22348257 | J:196539
 
First Author: Shoji H
Year: 2012
Journal: BMC Res Notes
Title: Comprehensive behavioral analysis of ENU-induced Disc1-Q31L and -L100P mutant mice.
Volume: 5
Pages: 108
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Publication
36012679 | J:327954
 
First Author: Lai CC
Year: 2022
Journal: Int J Mol Sci
Title: Chronic N-Acetylcysteine Treatment Prevents Amphetamine-Induced Hyperactivity in Heterozygous Disc1 Mutant Mice, a Putative Prodromal Schizophrenia Animal Model.
Volume: 23
Issue: 16
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Publication
32431597 | J:291248
 
First Author: Sultana R
Year: 2020
Journal: Front Cell Neurosci
Title: Disc1 Carrier Mice Exhibit Alterations in Neural pIGF-1Rβ and Related Kinase Expression.
Volume: 14
Pages: 94
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Publication
23631734 | J:250087
 
First Author: Lee FH
Year: 2013
Journal: Mol Brain
Title: Abnormal interneuron development in disrupted-in-schizophrenia-1 L100P mutant mice.
Volume: 6
Pages: 20
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Publication
24712988 | J:228486
First Author: Booth CA
Year: 2014
Journal: Eur J Neurosci
Title: Neurophysiological modification of CA1 pyramidal neurons in a transgenic mouse expressing a truncated form of disrupted-in-schizophrenia 1.
Volume: 39
Issue: 7
Pages: 1074-90
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