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Search results 1 to 100 out of 225 for Dlc1

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Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: zebrafish
Gene
Type: gene
Organism: chimpanzee
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: rat
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Domain
Type: Family
Description: Rho GTPase-activating protein 7 (also known as DLC1) is a tumour suppressor that functions as a Rho GTPase-activating protein (RhoGAP) and a negative regulator of specific Rho family proteins (RhoA-C and Cdc42) [, ].
Publication  
First Author: Shih YP
Year: 2017
Journal: Cancer Lett
Title: Down-regulation of DLC1 in endothelial cells compromises the angiogenesis process.
Volume: 398
Pages: 46-51
Publication
First Author: Sabbir MG
Year: 2012
Journal: PLoS One
Title: The role of Dlc1 isoform 2 in K-Ras2(G12D) induced thymic cancer.
Volume: 7
Issue: 7
Pages: e40302
Publication  
First Author: Ko FC
Year: 2013
Journal: Nat Commun
Title: PKA-induced dimerization of the RhoGAP DLC1 promotes its inhibition of tumorigenesis and metastasis.
Volume: 4
Pages: 1618
Publication
First Author: Qian X
Year: 2012
Journal: Cancer Res
Title: Inactivation of the Dlc1 gene cooperates with downregulation of p15INK4b and p16Ink4a, leading to neoplastic transformation and poor prognosis in human cancer.
Volume: 72
Issue: 22
Pages: 5900-11
Publication  
First Author: Sabbir MG
Year: 2010
Journal: BMC Biol
Title: Identification and characterization of Dlc1 isoforms in the mouse and study of the biological function of a single gene trapped isoform.
Volume: 8
Pages: 17
Protein
Organism: Mus musculus/domesticus
Length: 1092  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 137  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 373  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 1543  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 1126  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 469  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 80  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 216  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 1092  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 1543  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 431  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 1092  
Fragment?: false
Publication
First Author: Kim TY
Year: 2008
Journal: J Biol Chem
Title: Effects of structure of Rho GTPase-activating protein DLC-1 on cell morphology and migration.
Volume: 283
Issue: 47
Pages: 32762-70
Publication
First Author: Kim TY
Year: 2009
Journal: Cancer Metastasis Rev
Title: Role of DLC-1, a tumor suppressor protein with RhoGAP activity, in regulation of the cytoskeleton and cell motility.
Volume: 28
Issue: 1-2
Pages: 77-83
Publication
First Author: Wang Y
Year: 2014
Journal: J Clin Invest
Title: DLC1-dependent parathyroid hormone-like hormone inhibition suppresses breast cancer bone metastasis.
Volume: 124
Issue: 4
Pages: 1646-59
Publication
First Author: Sim CK
Year: 2017
Journal: PLoS One
Title: Regulation of white and brown adipocyte differentiation by RhoGAP DLC1.
Volume: 12
Issue: 3
Pages: e0174761
Publication
First Author: Shih YP
Year: 2015
Journal: Biochim Biophys Acta
Title: Tensin1 positively regulates RhoA activity through its interaction with DLC1.
Volume: 1853
Issue: 12
Pages: 3258-65
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Yuan BZ
Year: 1999
Journal: Cytogenet Cell Genet
Title: Assignment and cloning of mouse Arhgap7 to chromosome 8A4-B2, a conserved syntenic region of human chromosome 8p22-->p21.
Volume: 87
Issue: 3-4
Pages: 189-90
Publication
First Author: Durkin ME
Year: 2005
Journal: FEBS Lett
Title: DLC-1, a Rho GTPase-activating protein with tumor suppressor function, is essential for embryonic development.
Volume: 579
Issue: 5
Pages: 1191-6
GXD Expression      
Probe: MGI:3772675
Assay Type: Northern blot
Annotation Date: 2008-03-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:3772676
Age: postnatal
Specimen Label: Heart +/- 15
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:3772675
Assay Type: Northern blot
Annotation Date: 2008-03-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:3772676
Age: postnatal
Specimen Label: Heart +/- 11
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:3772675
Assay Type: Northern blot
Annotation Date: 2008-03-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:3772676
Age: postnatal
Specimen Label: Heart +/+ 15
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:3772675
Assay Type: Northern blot
Annotation Date: 2008-03-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:3772676
Age: postnatal
Specimen Label: Heart +/+ 11
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:3772675
Assay Type: Northern blot
Annotation Date: 2008-03-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:3772676
Age: postnatal
Specimen Label: Liver +/- 15
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:3772675
Assay Type: Northern blot
Annotation Date: 2008-03-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:3772676
Age: postnatal
Specimen Label: Liver +/- 11
Detected: true
Specimen Num: 6
GXD Expression      
Probe: MGI:3772675
Assay Type: Northern blot
Annotation Date: 2008-03-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:3772676
Age: postnatal
Specimen Label: Liver +/+ 15
Detected: true
Specimen Num: 7
GXD Expression      
Probe: MGI:3772675
Assay Type: Northern blot
Annotation Date: 2008-03-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:3772676
Age: postnatal
Specimen Label: Liver +/+ 11
Detected: true
Specimen Num: 8
GXD Expression    
Probe: MGI:7563922
Assay Type: Northern blot
Annotation Date: 2023-12-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:7563938
Age: postnatal adult
Image: 2
Specimen Label: Brain
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:7563922
Assay Type: Northern blot
Annotation Date: 2023-12-05
Strength: Present
Sex: Female
Emaps: EMAPS:3568928
Stage: TS28
Assay Id: MGI:7563938
Age: postnatal adult
Image: 2
Specimen Label: Placenta
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:7563922
Assay Type: Northern blot
Annotation Date: 2023-12-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:7563938
Age: postnatal adult
Image: 2
Specimen Label: Liver
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:7563922
Assay Type: Northern blot
Annotation Date: 2023-12-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672828
Stage: TS28
Assay Id: MGI:7563938
Age: postnatal adult
Image: 2
Specimen Label: Lung
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:7563922
Assay Type: Northern blot
Annotation Date: 2023-12-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:7563938
Age: postnatal adult
Image: 2
Specimen Label: Heart
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:7563922
Assay Type: Northern blot
Annotation Date: 2023-12-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876828
Stage: TS28
Assay Id: MGI:7563938
Age: postnatal adult
Image: 2
Specimen Label: Thymus
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:7563922
Assay Type: Northern blot
Annotation Date: 2023-12-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:7563938
Age: postnatal adult
Image: 2
Specimen Label: Kidney
Detected: true
Specimen Num: 7
GXD Expression    
Probe: MGI:7563927
Assay Type: RT-PCR
Annotation Date: 2023-12-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:7563940
Age: postnatal adult
Image: 3
Specimen Label: Spleen
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:7563927
Assay Type: RT-PCR
Annotation Date: 2023-12-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1752528
Stage: TS28
Assay Id: MGI:7563940
Age: postnatal adult
Image: 3
Specimen Label: Skin
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:7563927
Assay Type: RT-PCR
Annotation Date: 2023-12-05
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:7563940
Age: postnatal adult
Image: 3
Specimen Label: Testis
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:7563927
Assay Type: RT-PCR
Annotation Date: 2023-12-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:7563940
Age: postnatal adult
Image: 3
Specimen Label: Liver
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:7563927
Assay Type: RT-PCR
Annotation Date: 2023-12-05
Strength: Present
Sex: Female
Emaps: EMAPS:3568928
Stage: TS28
Assay Id: MGI:7563940
Age: postnatal adult
Image: 3
Specimen Label: Placenta
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:7563927
Assay Type: RT-PCR
Annotation Date: 2023-12-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:7563940
Age: postnatal adult
Image: 3
Specimen Label: Kidney
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:7563927
Assay Type: RT-PCR
Annotation Date: 2023-12-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1702128
Stage: TS28
Assay Id: MGI:7563940
Age: postnatal adult
Image: 3
Specimen Label: Stomach
Detected: true
Specimen Num: 7
GXD Expression    
Probe: MGI:7563927
Assay Type: RT-PCR
Annotation Date: 2023-12-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876828
Stage: TS28
Assay Id: MGI:7563940
Age: postnatal adult
Image: 3
Specimen Label: Thymus
Detected: true
Specimen Num: 8
GXD Expression    
Probe: MGI:7563927
Assay Type: RT-PCR
Annotation Date: 2023-12-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:7563940
Age: postnatal adult
Image: 3
Specimen Label: Brain
Detected: true
Specimen Num: 9
GXD Expression    
Probe: MGI:7563927
Assay Type: RT-PCR
Annotation Date: 2023-12-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672828
Stage: TS28
Assay Id: MGI:7563940
Age: postnatal adult
Image: 3
Specimen Label: Lung
Detected: true
Specimen Num: 10
GXD Expression    
Probe: MGI:7563927
Assay Type: RT-PCR
Annotation Date: 2023-12-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:7563940
Age: postnatal adult
Image: 3
Specimen Label: Heart
Detected: true
Specimen Num: 11
GXD Expression    
Probe: MGI:7563926
Assay Type: RT-PCR
Annotation Date: 2023-12-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:7563941
Age: postnatal adult
Image: 3
Specimen Label: Spleen
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:7563926
Assay Type: RT-PCR
Annotation Date: 2023-12-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1752528
Stage: TS28
Assay Id: MGI:7563941
Age: postnatal adult
Image: 3
Specimen Label: Skin
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:7563926
Assay Type: RT-PCR
Annotation Date: 2023-12-05
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:7563941
Age: postnatal adult
Image: 3
Specimen Label: Testis
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:7563926
Assay Type: RT-PCR
Annotation Date: 2023-12-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:7563941
Age: postnatal adult
Image: 3
Specimen Label: Liver
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:7563926
Assay Type: RT-PCR
Annotation Date: 2023-12-05
Strength: Present
Sex: Female
Emaps: EMAPS:3568928
Stage: TS28
Assay Id: MGI:7563941
Age: postnatal adult
Image: 3
Specimen Label: Placenta
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:7563926
Assay Type: RT-PCR
Annotation Date: 2023-12-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:7563941
Age: postnatal adult
Image: 3
Specimen Label: Kidney
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:7563926
Assay Type: RT-PCR
Annotation Date: 2023-12-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1702128
Stage: TS28
Assay Id: MGI:7563941
Age: postnatal adult
Image: 3
Specimen Label: Stomach
Detected: true
Specimen Num: 7
GXD Expression    
Probe: MGI:7563926
Assay Type: RT-PCR
Annotation Date: 2023-12-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876828
Stage: TS28
Assay Id: MGI:7563941
Age: postnatal adult
Image: 3
Specimen Label: Thymus
Detected: true
Specimen Num: 8
GXD Expression    
Probe: MGI:7563926
Assay Type: RT-PCR
Annotation Date: 2023-12-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:7563941
Age: postnatal adult
Image: 3
Specimen Label: Brain
Detected: true
Specimen Num: 9
GXD Expression    
Probe: MGI:7563926
Assay Type: RT-PCR
Annotation Date: 2023-12-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672828
Stage: TS28
Assay Id: MGI:7563941
Age: postnatal adult
Image: 3
Specimen Label: Lung
Detected: true
Specimen Num: 10
GXD Expression    
Probe: MGI:7563926
Assay Type: RT-PCR
Annotation Date: 2023-12-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:7563941
Age: postnatal adult
Image: 3
Specimen Label: Heart
Detected: true
Specimen Num: 11
GXD Expression    
Probe: MGI:7563924
Assay Type: RT-PCR
Annotation Date: 2023-12-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:7563944
Age: postnatal adult
Image: 3
Specimen Label: Spleen
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:7563924
Assay Type: RT-PCR
Annotation Date: 2023-12-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1752528
Stage: TS28
Assay Id: MGI:7563944
Age: postnatal adult
Image: 3
Specimen Label: Skin
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:7563924
Assay Type: RT-PCR
Annotation Date: 2023-12-05
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:7563944
Age: postnatal adult
Image: 3
Specimen Label: Testis
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:7563924
Assay Type: RT-PCR
Annotation Date: 2023-12-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:7563944
Age: postnatal adult
Image: 3
Specimen Label: Liver
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:7563924
Assay Type: RT-PCR
Annotation Date: 2023-12-05
Strength: Present
Sex: Female
Emaps: EMAPS:3568928
Stage: TS28
Assay Id: MGI:7563944
Age: postnatal adult
Image: 3
Specimen Label: Placenta
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:7563924
Assay Type: RT-PCR
Annotation Date: 2023-12-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:7563944
Age: postnatal adult
Image: 3
Specimen Label: Kidney
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:7563924
Assay Type: RT-PCR
Annotation Date: 2023-12-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1702128
Stage: TS28
Assay Id: MGI:7563944
Age: postnatal adult
Image: 3
Specimen Label: Stomach
Detected: true
Specimen Num: 7
GXD Expression    
Probe: MGI:7563924
Assay Type: RT-PCR
Annotation Date: 2023-12-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876828
Stage: TS28
Assay Id: MGI:7563944
Age: postnatal adult
Image: 3
Specimen Label: Thymus
Detected: true
Specimen Num: 8
GXD Expression    
Probe: MGI:7563924
Assay Type: RT-PCR
Annotation Date: 2023-12-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:7563944
Age: postnatal adult
Image: 3
Specimen Label: Brain
Detected: true
Specimen Num: 9