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Search results 1 to 91 out of 91 for Dlg5

0.026s
Type Details Score
Gene
Type: gene
Organism: Homo sapiens
Gene
Type: gene
Organism: Drosophila melanogaster
Gene
Type: gene
Organism: Rattus norvegicus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Gene
Type: gene
Organism: Homo sapiens
Publication
First Author: Nechiporuk T
Year: 2013
Journal: Dev Biol
Title: Dlg5 maintains apical aPKC and regulates progenitor differentiation during lung morphogenesis.
Volume: 377
Issue: 2
Pages: 375-84
Publication
First Author: Wang SH
Year: 2014
Journal: J Neurosci
Title: Dlg5 regulates dendritic spine formation and synaptogenesis by controlling subcellular N-cadherin localization.
Volume: 34
Issue: 38
Pages: 12745-61
Publication
First Author: Kwan J
Year: 2016
Journal: Genes Dev
Title: DLG5 connects cell polarity and Hippo signaling protein networks by linking PAR-1 with MST1/2.
Volume: 30
Issue: 24
Pages: 2696-2709
GXD Expression
Probe: MGI:6202891
Assay Type: Immunohistochemistry
Annotation Date: 2018-10-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3286022
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:6203057
Age: embryonic day 14.5
Image: 5A/C
Note: Expression was localized to the apical membrane domains. There was a partial colocalization of Dlg5 and Prkci/Prkcz.
Detected: true
Specimen Num: 1
Publication
First Author: Nechiporuk T
Year: 2007
Journal: Dev Cell
Title: Failure of epithelial tube maintenance causes hydrocephalus and renal cysts in Dlg5-/- mice.
Volume: 13
Issue: 3
Pages: 338-50
Publication
First Author: Chong YC
Year: 2015
Journal: Genes Dev
Title: Bifurcating action of Smoothened in Hedgehog signaling is mediated by Dlg5.
Volume: 29
Issue: 3
Pages: 262-76
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
GXD Expression    
Probe: MGI:6202891
Assay Type: Western blot
Annotation Date: 2018-10-22
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1672823
Stage: TS23
Assay Id: MGI:6203050
Age: embryonic day 15.5
Image: 4
Detected: false
Specimen Num: 4
GXD Expression    
Probe: MGI:6202891
Assay Type: Western blot
Annotation Date: 2018-10-22
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1672823
Stage: TS23
Assay Id: MGI:6203050
Age: embryonic day 15.5
Image: 4
Detected: false
Specimen Num: 3
GXD Expression    
Probe: MGI:6202891
Assay Type: Western blot
Annotation Date: 2018-10-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672823
Stage: TS23
Assay Id: MGI:6203050
Age: embryonic day 15.5
Image: 4
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:6202891
Assay Type: Western blot
Annotation Date: 2018-10-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672823
Stage: TS23
Assay Id: MGI:6203050
Age: embryonic day 15.5
Image: 4
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:6202891
Assay Type: Western blot
Annotation Date: 2018-10-19
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1672821
Stage: TS21
Assay Id: MGI:6202997
Age: embryonic day 13.5
Image: 2
Detected: false
Specimen Num: 2
GXD Expression    
Probe: MGI:6202891
Assay Type: Western blot
Annotation Date: 2018-10-19
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672821
Stage: TS21
Assay Id: MGI:6202997
Age: embryonic day 13.5
Image: 2
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:6202891
Assay Type: Immunohistochemistry
Annotation Date: 2018-10-22
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3286622
Stage: TS22
Assay Id: MGI:6203057
Age: embryonic day 14.5
Image: 5A'/C'
Detected: false
Specimen Num: 2
GXD Expression
Probe: MGI:6202891
Assay Type: Immunohistochemistry
Annotation Date: 2018-10-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3286622
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:6203057
Age: embryonic day 14.5
Image: 5A/C
Note: Expression in mesenchymal cells was lesser than in epithelial cells.
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:6202891
Assay Type: Immunohistochemistry
Annotation Date: 2018-10-22
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3286022
Stage: TS22
Assay Id: MGI:6203057
Age: embryonic day 14.5
Image: 5A'/C'
Detected: false
Specimen Num: 2
GXD Expression
Probe: MGI:6202885
Assay Type: RNA in situ
Annotation Date: 2018-10-19
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3286021
Pattern: Regionally restricted
Stage: TS21
Assay Id: MGI:6202995
Age: embryonic day 13.5
Image: 2F
Note: Highest levels of expression were present in the epithelial tubes.
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:6202885
Assay Type: RNA in situ
Annotation Date: 2018-10-19
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672821
Pattern: Widespread
Stage: TS21
Assay Id: MGI:6202995
Age: embryonic day 13.5
Image: 2F
Detected: true
Specimen Num: 1
Publication
First Author: Wakabayashi M
Year: 2003
Journal: J Biol Chem
Title: Interaction of lp-dlg/KIAA0583, a membrane-associated guanylate kinase family protein, with vinexin and beta-catenin at sites of cell-cell contact.
Volume: 278
Issue: 24
Pages: 21709-14
Publication
First Author: Yu H
Year: 2016
Journal: J Clin Invest
Title: A role for genetic susceptibility in sporadic focal segmental glomerulosclerosis.
Volume: 126
Issue: 3
Pages: 1067-78
Publication
First Author: Okazaki N
Year: 2003
Journal: DNA Res
Title: Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.
Volume: 10
Issue: 4
Pages: 167-80
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: RIKEN Data Curation in Mouse Genome Informatics
Publication
First Author: Friedel RH
Year: 2007
Journal: Brief Funct Genomic Proteomic
Title: EUCOMM--the European conditional mouse mutagenesis program.
Volume: 6
Issue: 3
Pages: 180-5
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
Publication      
First Author: International Knockout Mouse Consortium
Year: 2014
Journal: Database Download
Title: MGI download of modified allele data from IKMC and creation of new knockout alleles
Publication      
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
Publication      
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
Publication      
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
Publication
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
Publication
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
Publication
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
Publication
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
Publication      
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
Publication
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
Publication      
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
Publication      
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2000
Title: Gene Ontology Annotation by electronic association of SwissProt Keywords with GO terms
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication      
First Author: Mouse Genome Informatics, the Protein Information Resource and the Protein Ontology Consortium
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Protein
Organism: Mus musculus
Length: 1572  
Fragment?: true
Protein
Organism: Mus musculus
Length: 215  
Fragment?: false
Publication
First Author: Sezaki T
Year: 2013
Journal: FEBS Lett
Title: Dlg5 interacts with the TGF-β receptor and promotes its degradation.
Volume: 587
Issue: 11
Pages: 1624-9
Publication
First Author: Liu J
Year: 2014
Journal: Int J Biol Sci
Title: DLG5 in cell polarity maintenance and cancer development.
Volume: 10
Issue: 5
Pages: 543-9
Interaction Experiment
Description: Dlg5 interacts with the TGF-βreceptor and promotes its degradation.
Interaction Experiment
Description: Dlg5 interacts with the TGF-βreceptor and promotes its degradation.
Publication
First Author: Friedrichs F
Year: 2006
Journal: World J Gastroenterol
Title: Role of discs large homolog 5.
Volume: 12
Issue: 23
Pages: 3651-6
Publication
First Author: Sezaki T
Year: 2012
Journal: PLoS One
Title: Role of Dlg5/lp-dlg, a membrane-associated guanylate kinase family protein, in epithelial-mesenchymal transition in LLc-PK1 renal epithelial cells.
Volume: 7
Issue: 4
Pages: e35519
Publication
First Author: González-Mariscal L
Year: 2000
Journal: Semin Cell Dev Biol
Title: MAGUK proteins: structure and role in the tight junction.
Volume: 11
Issue: 4
Pages: 315-24
Protein Domain
Type: Domain
Description: DLG5 is a multifunctional scaffold protein that is located at sites of cell-cell contact and is involved in the maintenance of cell shape and polarity [, ]. Mutations in the DLG5 gene are associated with Crohn's disease (CD) and inflammatory bowel disease (IBD) []. DLG5 is a member of the MAGUK (membrane-associated guanylate kinase) protein family, which is characterised by the presence of a core of three domains: PDZ, SH3, and guanylate kinase (GuK) []. The GuK domain in MAGUK proteins is enzymatically inactive; instead, the domain mediates protein-protein interactions and associates intramolecularly with the SH3 domain []. DLG5 contains 4 PDZ domains as well as an N-terminal domain of unknown function.
Publication
First Author: Pan L
Year: 2011
Journal: J Biol Chem
Title: The structure of the PDZ3-SH3-GuK tandem of ZO-1 protein suggests a supramodular organization of the membrane-associated guanylate kinase (MAGUK) family scaffold protein core.
Volume: 286
Issue: 46
Pages: 40069-74
Protein
Organism: Mus musculus
Length: 1572  
Fragment?: true
Protein
Organism: Mus musculus
Length: 1921  
Fragment?: false
Protein
Organism: Mus musculus
Length: 1898  
Fragment?: false
Protein
Organism: Mus musculus
Length: 1898  
Fragment?: false
Publication
First Author: Gerhard DS
Year: 2004
Journal: Genome Res
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Volume: 14
Issue: 10B
Pages: 2121-7