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Search results 1 to 100 out of 383 for Dmc1

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0.039s
Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: zebrafish
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Protein Domain
Type: Family
Description: Dmc1 is a meiosis-specific RecA homologue []. It is a recombinase required for interhomologue recombination and double-strand break repair during meiosis [, , , ].
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: chimpanzee
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Publication
First Author: Pezza RJ
Year: 2007
Journal: Genes Dev
Title: Hop2/Mnd1 acts on two critical steps in Dmc1-promoted homologous pairing.
Volume: 21
Issue: 14
Pages: 1758-66
Publication
First Author: Shinohara M
Year: 2000
Journal: Proc Natl Acad Sci U S A
Title: Tid1/Rdh54 promotes colocalization of rad51 and dmc1 during meiotic recombination.
Volume: 97
Issue: 20
Pages: 10814-9
Publication
First Author: Couteau F
Year: 1999
Journal: Plant Cell
Title: Random chromosome segregation without meiotic arrest in both male and female meiocytes of a dmc1 mutant of Arabidopsis.
Volume: 11
Issue: 9
Pages: 1623-34
GXD Expression  
Probe: MGI:5800320
Assay Type: Immunohistochemistry
Annotation Date: 2023-07-18
Strength: Present
Sex: Male
Emaps: EMAPS:3148428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:7509253
Age: postnatal day 18
Image: 6D DMC1 +/-
Specimen Label: 6D DMC1 +/-
Detected: true
Specimen Num: 1
GXD Expression
Probe: MGI:5800320
Assay Type: Immunohistochemistry
Annotation Date: 2023-07-18
Strength: Present
Sex: Male
Emaps: EMAPS:3148428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:7509253
Age: postnatal day 18
Image: 6D DMC1 -/-
Note: Number of DMC1-positive foci decreased significatnly compared to wild type.
Specimen Label: 6D DMC1 -/-
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:3583135
Assay Type: RT-PCR
Annotation Date: 2010-12-09
Strength: Absent
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:4843297
Age: postnatal month 4
Specimen Label: Dmc1
Detected: false
Specimen Num: 6
GXD Expression      
Probe: MGI:3583135
Assay Type: RT-PCR
Annotation Date: 2010-12-09
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:4843302
Age: postnatal month 4
Specimen Label: Dmc1
Detected: true
Specimen Num: 6
Publication
First Author: Hayase A
Year: 2004
Journal: Cell
Title: A protein complex containing Mei5 and Sae3 promotes the assembly of the meiosis-specific RecA homolog Dmc1.
Volume: 119
Issue: 7
Pages: 927-40
Protein
Organism: Mus musculus/domesticus
Length: 340  
Fragment?: false
Publication
First Author: Reinholdt LG
Year: 2005
Journal: Chromosoma
Title: Mei1 is epistatic to Dmc1 during mouse meiosis.
Volume: 114
Issue: 2
Pages: 127-34
Publication
First Author: Bannister LA
Year: 2007
Journal: PLoS Biol
Title: A dominant, recombination-defective allele of Dmc1 causing male-specific sterility.
Volume: 5
Issue: 5
Pages: e105
Protein
Organism: Mus musculus/domesticus
Length: 340  
Fragment?: false
Publication
First Author: Yoshida K
Year: 1998
Journal: Mol Cell
Title: The mouse RecA-like gene Dmc1 is required for homologous chromosome synapsis during meiosis.
Volume: 1
Issue: 5
Pages: 707-18
Publication
First Author: Tran TN
Year: 2018
Journal: Hum Mol Genet
Title: A putative human infertility allele of the meiotic recombinase DMC1 does not affect fertility in mice.
Volume: 27
Issue: 22
Pages: 3911-3918
Publication
First Author: Dray E
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Molecular basis for enhancement of the meiotic DMC1 recombinase by RAD51 associated protein 1 (RAD51AP1).
Volume: 108
Issue: 9
Pages: 3560-5
Publication
First Author: Petukhova GV
Year: 2005
Journal: Nat Struct Mol Biol
Title: The Hop2 and Mnd1 proteins act in concert with Rad51 and Dmc1 in meiotic recombination.
Volume: 12
Issue: 5
Pages: 449-53
Publication
First Author: Hinch AG
Year: 2020
Journal: Mol Cell
Title: The Configuration of RPA, RAD51, and DMC1 Binding in Meiosis Reveals the Nature of Critical Recombination Intermediates.
Volume: 79
Issue: 4
Pages: 689-701.e10
Publication
First Author: Slotman JA
Year: 2020
Journal: PLoS Genet
Title: Super-resolution imaging of RAD51 and DMC1 in DNA repair foci reveals dynamic distribution patterns in meiotic prophase.
Volume: 16
Issue: 6
Pages: e1008595
Publication
First Author: Ito M
Year: 2023
Journal: Nat Commun
Title: FIGNL1 AAA+ ATPase remodels RAD51 and DMC1 filaments in pre-meiotic DNA replication and meiotic recombination.
Volume: 14
Issue: 1
Pages: 6857
Publication
First Author: Shang Y
Year: 2020
Journal: Nucleic Acids Res
Title: MEIOK21: a new component of meiotic recombination bridges required for spermatogenesis.
Volume: 48
Issue: 12
Pages: 6624-6639
Publication
First Author: Enomoto R
Year: 2004
Journal: J Biol Chem
Title: Positive role of the mammalian TBPIP/HOP2 protein in DMC1-mediated homologous pairing.
Volume: 279
Issue: 34
Pages: 35263-72
Publication
First Author: Pittman DL
Year: 1998
Journal: Mol Cell
Title: Meiotic prophase arrest with failure of chromosome synapsis in mice deficient for Dmc1, a germline-specific RecA homolog.
Volume: 1
Issue: 5
Pages: 697-705
Publication
First Author: Dai J
Year: 2017
Journal: Cell Rep
Title: Meiotic Knockdown and Complementation Reveals Essential Role of RAD51 in Mouse Spermatogenesis.
Volume: 18
Issue: 6
Pages: 1383-1394
Publication
First Author: Yang F
Year: 2008
Journal: J Cell Biol
Title: Mouse TEX15 is essential for DNA double-strand break repair and chromosomal synapsis during male meiosis.
Volume: 180
Issue: 4
Pages: 673-9
Publication
First Author: Morozumi Y
Year: 2012
Journal: Nucleic Acids Res
Title: Human PSF concentrates DNA and stimulates duplex capture in DMC1-mediated homologous pairing.
Volume: 40
Issue: 7
Pages: 3031-41
Publication
First Author: Habu T
Year: 1996
Journal: Nucleic Acids Res
Title: The mouse and human homologs of DMC1, the yeast meiosis-specific homologous recombination gene, have a common unique form of exon-skipped transcript in meiosis.
Volume: 24
Issue: 3
Pages: 470-7
Publication
First Author: Li XC
Year: 2011
Journal: Genetics
Title: Genetic evidence that synaptonemal complex axial elements govern recombination pathway choice in mice.
Volume: 189
Issue: 1
Pages: 71-82
Publication
First Author: Widger A
Year: 2018
Journal: Nat Commun
Title: ATR is a multifunctional regulator of male mouse meiosis.
Volume: 9
Issue: 1
Pages: 2621
Publication
First Author: Paiano J
Year: 2020
Journal: Nat Commun
Title: ATM and PRDM9 regulate SPO11-bound recombination intermediates during meiosis.
Volume: 11
Issue: 1
Pages: 857
Publication
First Author: Zhang Q
Year: 2023
Journal: Nucleic Acids Res
Title: The FLIP-FIGNL1 complex regulates the dissociation of RAD51/DMC1 in homologous recombination and replication fork restart.
Volume: 51
Issue: 16
Pages: 8606-8622
Publication
First Author: Zhang J
Year: 2019
Journal: Nat Commun
Title: A meiosis-specific BRCA2 binding protein recruits recombinases to DNA double-strand breaks to ensure homologous recombination.
Volume: 10
Issue: 1
Pages: 722
Publication
First Author: Huang T
Year: 2023
Journal: Nucleic Acids Res
Title: SPIDR is required for homologous recombination during mammalian meiosis.
Volume: 51
Issue: 8
Pages: 3855-3868
Publication
First Author: Enguita-Marruedo A
Year: 2019
Journal: PLoS Genet
Title: Transition from a meiotic to a somatic-like DNA damage response during the pachytene stage in mouse meiosis.
Volume: 15
Issue: 1
Pages: e1007439
Publication
First Author: Menke DB
Year: 2003
Journal: Dev Biol
Title: Sexual differentiation of germ cells in XX mouse gonads occurs in an anterior-to-posterior wave.
Volume: 262
Issue: 2
Pages: 303-12
Publication
First Author: Di Giacomo M
Year: 2005
Journal: Proc Natl Acad Sci U S A
Title: Distinct DNA-damage-dependent and -independent responses drive the loss of oocytes in recombination-defective mouse mutants.
Volume: 102
Issue: 3
Pages: 737-42
Publication
First Author: Shin YH
Year: 2013
Journal: Biol Reprod
Title: Mouse HORMAD1 is a meiosis i checkpoint protein that modulates DNA double- strand break repair during female meiosis.
Volume: 89
Issue: 2
Pages: 29
Publication
First Author: Inagaki A
Year: 2016
Journal: Chromosoma
Title: Functions of the MRE11 complex in the development and maintenance of oocytes.
Volume: 125
Issue: 1
Pages: 151-62
Publication
First Author: Kumar R
Year: 2010
Journal: Genes Dev
Title: Functional conservation of Mei4 for meiotic DNA double-strand break formation from yeasts to mice.
Volume: 24
Issue: 12
Pages: 1266-80
Publication
First Author: Li XC
Year: 2007
Journal: PLoS Genet
Title: Mouse pachytene checkpoint 2 (trip13) is required for completing meiotic recombination but not synapsis.
Volume: 3
Issue: 8
Pages: e130
Publication
First Author: Souquet B
Year: 2013
Journal: PLoS Genet
Title: MEIOB targets single-strand DNA and is necessary for meiotic recombination.
Volume: 9
Issue: 9
Pages: e1003784
Publication
First Author: Liebe B
Year: 2006
Journal: Exp Cell Res
Title: Mutations that affect meiosis in male mice influence the dynamics of the mid-preleptotene and bouquet stages.
Volume: 312
Issue: 19
Pages: 3768-81
Publication
First Author: Finsterbusch F
Year: 2016
Journal: PLoS Genet
Title: Alignment of Homologous Chromosomes and Effective Repair of Programmed DNA Double-Strand Breaks during Mouse Meiosis Require the Minichromosome Maintenance Domain Containing 2 (MCMDC2) Protein.
Volume: 12
Issue: 10
Pages: e1006393
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Sato S
Year: 1995
Journal: DNA Res
Title: Characterization of a mouse recA-like gene specifically expressed in testis.
Volume: 2
Issue: 3
Pages: 147-50
Publication
First Author: Sato S
Year: 1995
Journal: DNA Res
Title: Expression profiles of a human gene identified as a structural homologue of meiosis-specific recA-like genes.
Volume: 2
Issue: 4
Pages: 183-6
Publication
First Author: Matsuda Y
Year: 1996
Journal: Chromosome Res
Title: Chromosome mapping of the mouse homologue of DMC1, the yeast meiosis-specific homologous recombination gene.
Volume: 4
Issue: 3
Pages: 249-50
Publication
First Author: Saban MR
Year: 2002
Journal: Am J Pathol
Title: Gene expression profiling of mouse bladder inflammatory responses to LPS, substance P, and antigen-stimulation.
Volume: 160
Issue: 6
Pages: 2095-110
GXD Expression    
Probe: MGI:3583135
Assay Type: RT-PCR
Annotation Date: 2005-08-09
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:3583209
Age: postnatal adult
Image: 3
Specimen Label: Dmc1h, +/+
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:3583135
Assay Type: RT-PCR
Annotation Date: 2005-08-09
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:3583209
Age: postnatal adult
Image: 3
Specimen Label: Dmc1h, -/-
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:3839406
Assay Type: RT-PCR
Annotation Date: 2009-04-17
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:3840470
Age: postnatal day 8
Image: S9
Specimen Label: +/+
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:3839406
Assay Type: RT-PCR
Annotation Date: 2009-04-17
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:3840470
Age: postnatal day 8
Image: S9
Specimen Label: -/-
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:5693084
Assay Type: RT-PCR
Annotation Date: 2015-10-23
Strength: Present
Sex: Male
Emaps: EMAPS:1797222
Stage: TS22
Assay Id: MGI:5693279
Age: embryonic day 14.5
Image: 4
Specimen Label: XY Cyp26b1-/-
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:5693084
Assay Type: RT-PCR
Annotation Date: 2015-10-23
Strength: Present
Sex: Male
Emaps: EMAPS:1797222
Stage: TS22
Assay Id: MGI:5693279
Age: embryonic day 14.5
Image: 4
Specimen Label: XY Cyp26b1-/-;Stra8-/-
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:5693084
Assay Type: RT-PCR
Annotation Date: 2015-10-23
Strength: Present
Sex: Female
Emaps: EMAPS:1796222
Stage: TS22
Assay Id: MGI:5693279
Age: embryonic day 14.5
Image: 4
Specimen Label: XX control
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:5693084
Assay Type: RT-PCR
Annotation Date: 2015-10-23
Strength: Present
Sex: Male
Emaps: EMAPS:1797222
Stage: TS22
Assay Id: MGI:5693279
Age: embryonic day 14.5
Image: 4
Specimen Label: XY control
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:5693084
Assay Type: RT-PCR
Annotation Date: 2015-10-23
Strength: Present
Sex: Female
Emaps: EMAPS:1796221
Stage: TS21
Assay Id: MGI:5693282
Age: embryonic day 13.5
Image: 5
Specimen Label: XX control
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:5693084
Assay Type: RT-PCR
Annotation Date: 2015-10-23
Strength: Present
Sex: Female
Emaps: EMAPS:1796221
Stage: TS21
Assay Id: MGI:5693282
Age: embryonic day 13.5
Image: 5
Specimen Label: XXRec8mei8/mei8
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:5906793
Assay Type: RT-PCR
Annotation Date: 2017-08-11
Strength: Present
Sex: Female
Emaps: EMAPS:1796221
Stage: TS21
Assay Id: MGI:5906817
Age: embryonic day 13.5
Specimen Label: WT
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:5906793
Assay Type: RT-PCR
Annotation Date: 2017-08-11
Strength: Present
Sex: Female
Emaps: EMAPS:1796221
Stage: TS21
Assay Id: MGI:5906817
Age: embryonic day 13.5
Specimen Label: GLP-1 null
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:29765
Assay Type: Northern blot
Annotation Date: 2020-05-08
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:6415580
Age: postnatal adult
Specimen Label: brain
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:29765
Assay Type: Northern blot
Annotation Date: 2020-05-08
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:6415580
Age: postnatal adult
Specimen Label: heart
Detected: false
Specimen Num: 2
GXD Expression      
Probe: MGI:29765
Assay Type: Northern blot
Annotation Date: 2020-05-08
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1876828
Stage: TS28
Assay Id: MGI:6415580
Age: postnatal adult
Specimen Label: thymus
Detected: false
Specimen Num: 3
GXD Expression      
Probe: MGI:29765
Assay Type: Northern blot
Annotation Date: 2020-05-08
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:6415580
Age: postnatal adult
Specimen Label: spleen
Detected: false
Specimen Num: 4
GXD Expression      
Probe: MGI:29765
Assay Type: Northern blot
Annotation Date: 2020-05-08
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:6415580
Age: postnatal adult
Specimen Label: kidney
Detected: false
Specimen Num: 5
GXD Expression      
Probe: MGI:29765
Assay Type: Northern blot
Annotation Date: 2020-05-08
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:6415580
Age: postnatal adult
Specimen Label: liver
Detected: false
Specimen Num: 6
GXD Expression      
Probe: MGI:29765
Assay Type: Northern blot
Annotation Date: 2020-05-08
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1702128
Stage: TS28
Assay Id: MGI:6415580
Age: postnatal adult
Specimen Label: stomach
Detected: false
Specimen Num: 7
GXD Expression      
Probe: MGI:29765
Assay Type: Northern blot
Annotation Date: 2020-05-08
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:6415580
Age: postnatal adult
Specimen Label: testis
Detected: true
Specimen Num: 8
GXD Expression      
Probe: MGI:29765
Assay Type: Northern blot
Annotation Date: 2020-05-08
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3271528
Stage: TS28
Assay Id: MGI:6415580
Age: postnatal adult
Specimen Label: muscle
Detected: false
Specimen Num: 9
GXD Expression      
Probe: MGI:29765
Assay Type: Northern blot
Annotation Date: 2020-05-08
Strength: Absent
Sex: Female
Emaps: EMAPS:1796228
Stage: TS28
Assay Id: MGI:6415580
Age: postnatal adult
Specimen Label: ovary
Detected: false
Specimen Num: 10
GXD Expression      
Probe: MGI:29765
Assay Type: Northern blot
Annotation Date: 2020-05-08
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1876828
Stage: TS28
Assay Id: MGI:6415585
Age: postnatal adult
Specimen Label: Thymus poly(A)+ RNA
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:29765
Assay Type: Northern blot
Annotation Date: 2020-05-08
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:6415585
Age: postnatal adult
Specimen Label: Testis poly(A)+ RNA
Detected: true
Specimen Num: 3