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Search results 1 to 100 out of 2629 for Dmd

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Type Details Score
Gene
1756 | DMD
Type: gene
Organism: human
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Gene
465559 | DMD
Type: gene
Organism: chimpanzee
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Gene
606758 | DMD
Type: gene
Organism: dog, domestic
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Gene
537655 | DMD
Type: gene
Organism: cattle
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Gene
540755 | DMD
Type: gene
Organism: cattle
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Gene
396236 | DMD
Type: gene
Organism: chicken
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Gene
83773 | dmd
Type: gene
Organism: zebrafish
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Gene
708073 | DMD
Type: gene
Organism: macaque, rhesus
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Gene
24907 | Dmd
Type: gene
Organism: rat
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Protein Domain
IPR035137 | Dmd
Type: Family
Description: This family includes Dmd peptides from T4 phages. Dmd can suppress the toxicities of toxins such as LsoA (an endoribonucleases toxin expressed by E.coli). Crystal structure analysis show that Dmd is inserted into the deep groove between the N-terminal repeated domain (NRD) and the Dmd-binding domain (DBD) of LsoA. Site-directed mutagenesis of Dmd revealed the conserved residues (W31 and N40) are necessary for LsoA binding and the toxicity suppression [].
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Protein Coding Gene
MGI:94909 | Dmd
Type: protein_coding_gene
Organism: mouse, laboratory
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Gene
100873916 | DMD-AS3
Type: gene
Organism: human
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Publication
27169810 | -
First Author: Wan H
Year: 2016
Journal: Mol Microbiol
Title: Structural insights into the inhibition mechanism of bacterial toxin LsoA by bacteriophage antitoxin Dmd.
Volume: 101
Issue: 5
Pages: 757-69
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GXD Expression
GXD Expression
   
Probe: MGI:7331385
Assay Type: Western blot
Annotation Date: 2022-08-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3578628
Stage: TS28
Assay Id: MGI:7331420
Age: postnatal adult
Image: S10
Specimen Label: DMD
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:7331385
Assay Type: Western blot
Annotation Date: 2022-08-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3578628
Stage: TS28
Assay Id: MGI:7331420
Age: postnatal adult
Image: S10
Specimen Label: DMD
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
   
Probe: MGI:7331385
Assay Type: Western blot
Annotation Date: 2022-08-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3578628
Stage: TS28
Assay Id: MGI:7331420
Age: postnatal adult
Image: S10
Specimen Label: DMD
Detected: true
Specimen Num: 6
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Publication
21824387 | J:183732
 
First Author: Alexander MS
Year: 2011
Journal: Skelet Muscle
Title: Regulation of DMD pathology by an ankyrin-encoded miRNA.
Volume: 1
Pages: 27
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Protein
A0A1Q1PRS6
Organism: Mus musculus/domesticus
Length: 507  
Fragment?: false
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Protein
A0A1Q1PRS9
Organism: Mus musculus/domesticus
Length: 582  
Fragment?: false
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Protein
A0A1Q1NN66
Organism: Mus musculus/domesticus
Length: 529  
Fragment?: false
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Protein
A0A1Q1PRS2
Organism: Mus musculus/domesticus
Length: 551  
Fragment?: false
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Protein
A0A1Q1PRT9
Organism: Mus musculus/domesticus
Length: 564  
Fragment?: false
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Protein
A0A1Q1PRS4
Organism: Mus musculus/domesticus
Length: 525  
Fragment?: false
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Publication
23863459 | J:203139
First Author: Rodino-Klapac LR
Year: 2013
Journal: Hum Mol Genet
Title: Micro-dystrophin and follistatin co-delivery restores muscle function in aged DMD model.
Volume: 22
Issue: 24
Pages: 4929-37
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Publication
18371406 | J:149808
First Author: Benchaouir R
Year: 2007
Journal: Cell Stem Cell
Title: Restoration of human dystrophin following transplantation of exon-skipping-engineered DMD patient stem cells into dystrophic mice.
Volume: 1
Issue: 6
Pages: 646-57
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Publication
37819629 | J:344470
First Author: Liu G
Year: 2024
Journal: Hum Mol Genet
Title: Comparison of pharmaceutical properties and biological activities of prednisolone, deflazacort, and vamorolone in DMD disease models.
Volume: 33
Issue: 3
Pages: 211-223
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Publication
9887326 | J:70757
First Author: Sarig R
Year: 1999
Journal: Hum Mol Genet
Title: Targeted inactivation of Dp71, the major non-muscle product of the DMD gene: differential activity of the Dp71 promoter during development.
Volume: 8
Issue: 1
Pages: 1-10
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Publication
18083704 | J:132320
First Author: 't Hoen PA
Year: 2008
Journal: J Biol Chem
Title: Generation and characterization of transgenic mice with the full-length human DMD gene.
Volume: 283
Issue: 9
Pages: 5899-907
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Publication
34581784 | J:343833
First Author: Mamsa H
Year: 2022
Journal: Hum Mol Genet
Title: Sarcospan increases laminin-binding capacity of α-dystroglycan to ameliorate DMD independent of Galgt2.
Volume: 31
Issue: 5
Pages: 718-732
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Publication
27382459 | J:315435
 
First Author: Petkova MV
Year: 2016
Journal: Skelet Muscle
Title: Characterization of a Dmd (EGFP) reporter mouse as a tool to investigate dystrophin expression.
Volume: 6
Pages: 25
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Publication
37071470 | J:337956
 
First Author: Roy A
Year: 2023
Journal: JCI Insight
Title: Targeted regulation of TAK1 counteracts dystrophinopathy in a DMD mouse model.
Volume: 8
Issue: 10
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Publication
25108525 | J:232155
First Author: Wein N
Year: 2014
Journal: Nat Med
Title: Translation from a DMD exon 5 IRES results in a functional dystrophin isoform that attenuates dystrophinopathy in humans and mice.
Volume: 20
Issue: 9
Pages: 992-1000
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Publication
32213706 | J:328085
 
First Author: Mázala DA
Year: 2020
Journal: JCI Insight
Title: TGF-β-driven muscle degeneration and failed regeneration underlie disease onset in a DMD mouse model.
Volume: 5
Issue: 6
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Publication
28334037 | J:245422
First Author: Gutpell KM
Year: 2017
Journal: PLoS One
Title: ANG1 treatment reduces muscle pathology and prevents a decline in perfusion in DMD mice.
Volume: 12
Issue: 3
Pages: e0174315
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Publication
3607877 | J:8795
First Author: Koenig M
Year: 1987
Journal: Cell
Title: Complete cloning of the Duchenne muscular dystrophy (DMD) cDNA and preliminary genomic organization of the DMD gene in normal and affected individuals.
Volume: 50
Issue: 3
Pages: 509-17
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Publication
30154729 | J:312054
 
First Author: Vitiello L
Year: 2018
Journal: Front Physiol
Title: Drug Repurposing for Duchenne Muscular Dystrophy: The Monoamine Oxidase B Inhibitor Safinamide Ameliorates the Pathological Phenotype in mdx Mice and in Myogenic Cultures From DMD Patients.
Volume: 9
Pages: 1087
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Publication
23575223 | J:198527
First Author: Amirouche A
Year: 2013
Journal: Hum Mol Genet
Title: Activation of p38 signaling increases utrophin A expression in skeletal muscle via the RNA-binding protein KSRP and inhibition of AU-rich element-mediated mRNA decay: implications for novel DMD therapeutics.
Volume: 22
Issue: 15
Pages: 3093-111
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Protein
Q5U476
Organism: Mus musculus/domesticus
Length: 749  
Fragment?: true
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Publication
32616572 | J:291549
First Author: García-Rodríguez R
Year: 2020
Journal: Proc Natl Acad Sci U S A
Title: Premature termination codons in the DMD gene cause reduced local mRNA synthesis.
Volume: 117
Issue: 28
Pages: 16456-16464
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Publication
32988972 | J:296560
 
First Author: Wong TWY
Year: 2020
Journal: Dis Model Mech
Title: A novel mouse model of Duchenne muscular dystrophy carrying a multi-exonic Dmd deletion exhibits progressive muscular dystrophy and early-onset cardiomyopathy.
Volume: 13
Issue: 9
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Publication
31028078 | J:275476
 
First Author: Egorova TV
Year: 2019
Journal: Dis Model Mech
Title: CRISPR/Cas9-generated mouse model of Duchenne muscular dystrophy recapitulating a newly identified large 430 kb deletion in the human DMD gene.
Volume: 12
Issue: 4
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Publication
12812982 | J:84454
First Author: Dalloz C
Year: 2003
Journal: Hum Mol Genet
Title: Targeted inactivation of dystrophin gene product Dp71: phenotypic impact in mouse retina.
Volume: 12
Issue: 13
Pages: 1543-54
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Publication
30051354 | J:328192
First Author: Chaussenot R
Year: 2019
Journal: Mol Neurobiol
Title: Dp71-Dystrophin Deficiency Alters Prefrontal Cortex Excitation-Inhibition Balance and Executive Functions.
Volume: 56
Issue: 4
Pages: 2670-2684
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Publication
29895670 | J:263651
 
First Author: Helleringer R
Year: 2018
Journal: Dis Model Mech
Title: Cerebellar synapse properties and cerebellum-dependent motor and non-motor performance in Dp71-null mice.
Volume: 11
Issue: 7
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Publication
25489223 | J:220257
 
First Author: Fort PE
Year: 2014
Journal: Mol Vis
Title: Lack of dystrophin protein Dp71 results in progressive cataract formation due to loss of fiber cell organization.
Volume: 20
Pages: 1480-90
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Publication
18586242 | J:138609
First Author: Takatoh J
Year: 2008
Journal: Exp Neurol
Title: Loss of short dystrophin isoform Dp71 in olfactory ensheathing cells causes vomeronasal nerve defasciculation in mouse olfactory system.
Volume: 213
Issue: 1
Pages: 36-47
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Publication
8355788 | J:14332
First Author: Cox GA
Year: 1993
Journal: Nature
Title: Overexpression of dystrophin in transgenic mdx mice eliminates dystrophic symptoms without toxicity.
Volume: 364
Issue: 6439
Pages: 725-9
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Publication
34884423 | J:328128
 
First Author: Lim KRQ
Year: 2021
Journal: Int J Mol Sci
Title: Natural History of a Mouse Model Overexpressing the Dp71 Dystrophin Isoform.
Volume: 22
Issue: 23
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Publication
28505980 | J:280218
First Author: Young CS
Year: 2017
Journal: J Neuromuscul Dis
Title: Creation of a Novel Humanized Dystrophic Mouse Model of Duchenne Muscular Dystrophy and Application of a CRISPR/Cas9 Gene Editing Therapy.
Volume: 4
Issue: 2
Pages: 139-145
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Publication
19649270 | J:152485
First Author: Daoud F
Year: 2008
Journal: PLoS One
Title: Role of mental retardation-associated dystrophin-gene product Dp71 in excitatory synapse organization, synaptic plasticity and behavioral functions.
Volume: 4
Issue: 8
Pages: e6574
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Publication
25901007 | J:223333
First Author: El Mathari B
Year: 2015
Journal: Hum Mol Genet
Title: Dystrophin Dp71 gene deletion induces retinal vascular inflammation and capillary degeneration.
Volume: 24
Issue: 14
Pages: 3939-47
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Publication
30642627 | J:295113
First Author: Benabdesselam R
Year: 2019
Journal: Acta Histochem
Title: Effect of Dp71 deficiency on the oxytocin hypothalamic axis in osmoregulation function in mice.
Volume: 121
Issue: 3
Pages: 268-276
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Publication
26711882 | J:231096
First Author: Giocanti-Auregan A
Year: 2016
Journal: Glia
Title: Altered astrocyte morphology and vascular development in dystrophin-Dp71-null mice.
Volume: 64
Issue: 5
Pages: 716-29
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Publication
24382652 | J:207503
First Author: Vacca O
Year: 2014
Journal: Glia
Title: AAV-mediated gene delivery in Dp71-null mouse model with compromised barriers.
Volume: 62
Issue: 3
Pages: 468-76
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Publication
32049345 | J:288295
First Author: Barboni MTS
Year: 2020
Journal: Invest Ophthalmol Vis Sci
Title: Rescue of Defective Electroretinographic Responses in Dp71-Null Mice With AAV-Mediated Reexpression of Dp71.
Volume: 61
Issue: 2
Pages: 11
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Publication
27288449 | J:237142
First Author: Vacca O
Year: 2016
Journal: Hum Mol Genet
Title: AAV-mediated gene therapy in Dystrophin-Dp71 deficient mouse leads to blood-retinal barrier restoration and oedema reabsorption.
Volume: 25
Issue: 14
Pages: 3070-3079
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Publication
18286645 | J:156279
First Author: Fort PE
Year: 2008
Journal: Glia
Title: Kir4.1 and AQP4 associate with Dp71- and utrophin-DAPs complexes in specific and defined microdomains of Müller retinal glial cell membrane.
Volume: 56
Issue: 6
Pages: 597-610
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Publication
33247858 | J:303686
First Author: Belmaati Cherkaoui M
Year: 2021
Journal: Glia
Title: Dp71 contribution to the molecular scaffold anchoring aquaporine-4 channels in brain macroglial cells.
Volume: 69
Issue: 4
Pages: 954-970
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Publication
31814696 | J:292472
 
First Author: Ortiz G
Year: 2019
Journal: Mol Vis
Title: Evidence of the involvement of dystrophin Dp71 in corneal angiogenesis.
Volume: 25
Pages: 714-721
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Publication
15694376 | J:96210
First Author: Kudoh H
Year: 2005
Journal: Biochem Biophys Res Commun
Title: A new model mouse for Duchenne muscular dystrophy produced by 2.4 Mb deletion of dystrophin gene using Cre-loxP recombination system.
Volume: 328
Issue: 2
Pages: 507-16
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Publication
19809515 | J:154103
First Author: Sene A
Year: 2009
Journal: PLoS One
Title: Functional implication of Dp71 in osmoregulation and vascular permeability of the retina.
Volume: 4
Issue: 10
Pages: e7329
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Publication
21402717 | J:174330
First Author: Avale ME
Year: 2011
Journal: FASEB J
Title: Prefrontal nicotinic receptors control novel social interaction between mice.
Volume: 25
Issue: 7
Pages: 2145-55
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Publication
29466448 | J:257449
First Author: Veltrop M
Year: 2018
Journal: PLoS One
Title: A dystrophic Duchenne mouse model for testing human antisense oligonucleotides.
Volume: 13
Issue: 2
Pages: e0193289
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Publication
33963238 | J:327406
First Author: Marchal GA
Year: 2021
Journal: Sci Rep
Title: Low human dystrophin levels prevent cardiac electrophysiological and structural remodelling in a Duchenne mouse model.
Volume: 11
Issue: 1
Pages: 9779
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Publication
25511460 | J:217682
 
First Author: Nishimura D
Year: 2015
Journal: Mech Dev
Title: Roles of ADAM8 in elimination of injured muscle fibers prior to skeletal muscle regeneration.
Volume: 135
Pages: 58-67
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Publication
33362201 | J:299478
First Author: Yavas A
Year: 2020
Journal: PLoS One
Title: Detailed genetic and functional analysis of the hDMDdel52/mdx mouse model.
Volume: 15
Issue: 12
Pages: e0244215
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Publication
21397023 | J:174331
First Author: Miranda R
Year: 2011
Journal: Neurobiol Dis
Title: Altered presynaptic ultrastructure in excitatory hippocampal synapses of mice lacking dystrophins Dp427 or Dp71.
Volume: 43
Issue: 1
Pages: 134-41
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Publication
23903056 | J:328054
First Author: Masubuchi N
Year: 2013
Journal: Exp Anim
Title: Subcellular localization of dystrophin isoforms in cardiomyocytes and phenotypic analysis of dystrophin-deficient mice reveal cardiac myopathy is predominantly caused by a deficiency in full-length dystrophin.
Volume: 62
Issue: 3
Pages: 211-7
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Publication
14555666 | J:103011
First Author: Wieneke S
Year: 2003
Journal: J Appl Physiol (1985)
Title: Acute pathophysiological effects of muscle-expressed Dp71 transgene on normal and dystrophic mouse muscle.
Volume: 95
Issue: 5
Pages: 1861-6
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Publication
21183068 | J:167707
First Author: Chamberlain JS
Year: 2010
Journal: Cell
Title: Duchenne muscular dystrophy models show their age.
Volume: 143
Issue: 7
Pages: 1040-2
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Publication
16565216 | J:108299
First Author: Hanft LM
Year: 2006
Journal: Proc Natl Acad Sci U S A
Title: Cytoplasmic gamma-actin contributes to a compensatory remodeling response in dystrophin-deficient muscle.
Volume: 103
Issue: 14
Pages: 5385-90
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Publication
18338794 | J:156273
First Author: Nicchia GP
Year: 2008
Journal: Glia
Title: Dystrophin-dependent and -independent AQP4 pools are expressed in the mouse brain.
Volume: 56
Issue: 8
Pages: 869-76
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Publication
3659917 | J:8862
First Author: Hoffman EP
Year: 1987
Journal: Science
Title: Conservation of the Duchenne muscular dystrophy gene in mice and humans.
Volume: 238
Issue: 4825
Pages: 347-50
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Publication
9359695 | J:44111
First Author: Deconinck N
Year: 1997
Journal: Nat Med
Title: Expression of truncated utrophin leads to major functional improvements in dystrophin-deficient muscles of mice.
Volume: 3
Issue: 11
Pages: 1216-21
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Publication
21212803 | J:168844
First Author: Cacchiarelli D
Year: 2011
Journal: EMBO Rep
Title: miR-31 modulates dystrophin expression: new implications for Duchenne muscular dystrophy therapy.
Volume: 12
Issue: 2
Pages: 136-41
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Publication
7581361 | J:27471
First Author: Phelps SF
Year: 1995
Journal: Hum Mol Genet
Title: Expression of full-length and truncated dystrophin mini-genes in transgenic mdx mice.
Volume: 4
Issue: 8
Pages: 1251-8
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Publication
26721686 | J:229477
First Author: Tabebordbar M
Year: 2016
Journal: Science
Title: In vivo gene editing in dystrophic mouse muscle and muscle stem cells.
Volume: 351
Issue: 6271
Pages: 407-411
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Publication
26018658 | J:224923
 
First Author: Rau F
Year: 2015
Journal: Nat Commun
Title: Abnormal splicing switch of DMD's penultimate exon compromises muscle fibre maintenance in myotonic dystrophy.
Volume: 6
Pages: 7205
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Publication
37582915 | J:339704
First Author: Heezen LGM
Year: 2023
Journal: Nat Commun
Title: Spatial transcriptomics reveal markers of histopathological changes in Duchenne muscular dystrophy mouse models.
Volume: 14
Issue: 1
Pages: 4909
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Publication
1992296 | J:116018
First Author: Wakeford S
Year: 1991
Journal: Muscle Nerve
Title: X-irradiation improves mdx mouse muscle as a model of myofiber loss in DMD.
Volume: 14
Issue: 1
Pages: 42-50
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Publication
32508664 | J:311441
 
First Author: Farini A
Year: 2020
Journal: Front Physiol
Title: PTX3 Predicts Myocardial Damage and Fibrosis in Duchenne Muscular Dystrophy.
Volume: 11
Pages: 403
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Publication
19965907 | J:157115
First Author: Di Certo MG
Year: 2010
Journal: Hum Mol Genet
Title: The artificial gene Jazz, a transcriptional regulator of utrophin, corrects the dystrophic pathology in mdx mice.
Volume: 19
Issue: 5
Pages: 752-60
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Publication
35089797 | J:328185
First Author: Laurila PP
Year: 2022
Journal: Sci Adv
Title: Inhibition of sphingolipid de novo synthesis counteracts muscular dystrophy.
Volume: 8
Issue: 4
Pages: eabh4423
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Publication
25123483 | J:216417
First Author: Long C
Year: 2014
Journal: Science
Title: Prevention of muscular dystrophy in mice by CRISPR/Cas9-mediated editing of germline DNA.
Volume: 345
Issue: 6201
Pages: 1184-1188
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Publication
7608742 | J:24527
First Author: Pastoret C
Year: 1995
Journal: J Neurol Sci
Title: mdx mice show progressive weakness and muscle deterioration with age.
Volume: 129
Issue: 2
Pages: 97-105
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Publication
8934518 | J:36822
First Author: Tinsley JM
Year: 1996
Journal: Nature
Title: Amelioration of the dystrophic phenotype of mdx mice using a truncated utrophin transgene.
Volume: 384
Issue: 6607
Pages: 349-53
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Publication
26626079 | J:259320
 
First Author: Fuenzalida M
Year: 2016
Journal: Neurobiol Dis
Title: Wnt signaling pathway improves central inhibitory synaptic transmission in a mouse model of Duchenne muscular dystrophy.
Volume: 86
Pages: 109-20
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Publication
37751291 | J:343612
 
First Author: Timpani CA
Year: 2023
Journal: JCI Insight
Title: Dimethyl fumarate modulates the dystrophic disease program following short-term treatment.
Volume: 8
Issue: 21
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Publication
10564714 | J:58586
First Author: Tkatchenko AV
Year: 2000
Journal: Biochim Biophys Acta
Title: Large-scale analysis of differential gene expression in the hindlimb muscles and diaphragm of mdx mouse.
Volume: 1500
Issue: 1
Pages: 17-30
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Publication
8880686 | J:35421
First Author: Tracey I
Year: 1996
Journal: J Neurol Sci
Title: An in vivo and in vitro H-magnetic resonance spectroscopy study of mdx mouse brain: abnormal development or neural necrosis?
Volume: 141
Issue: 1-2
Pages: 13-8
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Publication
26721684 | J:229478
First Author: Nelson CE
Year: 2016
Journal: Science
Title: In vivo genome editing improves muscle function in a mouse model of Duchenne muscular dystrophy.
Volume: 351
Issue: 6271
Pages: 403-7
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Publication
2407807 | J:121251
First Author: Karpati G
Year: 1990
Journal: J Neuropathol Exp Neurol
Title: Age-related conversion of dystrophin-negative to -positive fiber segments of skeletal but not cardiac muscle fibers in heterozygote mdx mice.
Volume: 49
Issue: 2
Pages: 96-105
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Publication
1439189 | J:3928
First Author: Brazeau GA
Year: 1992
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