Type |
Details |
Score |
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
Gene |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
dog, domestic |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chimpanzee |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
cattle |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
macaque, rhesus |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Publication |
First Author: |
Leclerc EA |
Year: |
2014 |
Journal: |
J Cell Sci |
Title: |
Mice deficient for the epidermal dermokine β and γ isoforms display transient cornification defects. |
Volume: |
127 |
Issue: |
Pt 13 |
Pages: |
2862-72 |
|
•
•
•
•
•
|
Publication |
First Author: |
Utsunomiya A |
Year: |
2020 |
Journal: |
J Invest Dermatol |
Title: |
Homeostatic Function of Dermokine in the Skin Barrier and Inflammation. |
Volume: |
140 |
Issue: |
4 |
Pages: |
838-849.e9 |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus caroli |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus pahari |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus spretus |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3712215 |
Assay Type: |
RNA in situ |
Annotation Date: |
2007-06-21 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1654222 |
Pattern: |
Not Specified |
Stage: |
TS22 |
Assay Id: |
MGI:3712216 |
Age: |
embryonic day 14.0 |
|
|
Specimen Label: |
Not shown |
Detected: |
true |
Specimen Num: |
9 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3712215 |
Assay Type: |
RNA in situ |
Annotation Date: |
2007-06-21 |
Strength: |
Strong |
Sex: |
Not Specified |
Emaps: |
EMAPS:1752823 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:3712216 |
Age: |
embryonic day 15.5 |
Image: |
2D |
Note: |
Expression is in the suprabasal layers of the developing epidermis. |
Specimen Label: |
2D |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3712215 |
Assay Type: |
RNA in situ |
Annotation Date: |
2007-06-21 |
Strength: |
Strong |
Sex: |
Not Specified |
Emaps: |
EMAPS:1752823 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:3712216 |
Age: |
embryonic day 15.5 |
Image: |
2E |
Note: |
Expression is in the suprabasal layers of the developing epidermis with less intense signals above the developing hair follicle placodes. |
Specimen Label: |
2E |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3712215 |
Assay Type: |
RNA in situ |
Annotation Date: |
2007-06-21 |
Strength: |
Strong |
Sex: |
Not Specified |
Emaps: |
EMAPS:1752823 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:3712216 |
Age: |
embryonic day 15.5 |
Image: |
2F |
Note: |
Expression is in the suprabasal layers of the developing epidermis. |
Specimen Label: |
2F |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3712215 |
Assay Type: |
RNA in situ |
Annotation Date: |
2007-06-21 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1785022 |
Pattern: |
Not Specified |
Stage: |
TS22 |
Assay Id: |
MGI:3712216 |
Age: |
embryonic day 14.5 |
Image: |
6A |
Note: |
Higher magnification was shown in the inset. |
Specimen Label: |
6A |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3712215 |
Assay Type: |
RNA in situ |
Annotation Date: |
2007-06-21 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1785022 |
Pattern: |
Regionally restricted |
Stage: |
TS22 |
Assay Id: |
MGI:3712216 |
Age: |
embryonic day 15.0 |
Image: |
6J,K |
Note: |
Expression is in the stratifying nasal epithelium. |
Specimen Label: |
6J,K |
Detected: |
true |
Specimen Num: |
7 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3712215 |
Assay Type: |
RNA in situ |
Annotation Date: |
2007-06-21 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1752523 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:3712216 |
Age: |
embryonic day 15.5 |
Image: |
6B |
Note: |
Expression is in larger areas of the skin as development progresses, it is absent in the scalp region. |
Specimen Label: |
6B |
Detected: |
true |
Specimen Num: |
5 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3712215 |
Assay Type: |
RNA in situ |
Annotation Date: |
2007-06-21 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1752524 |
Pattern: |
Uniform |
Stage: |
TS24 |
Assay Id: |
MGI:3712216 |
Age: |
embryonic day 16.5 |
Image: |
6C |
|
Specimen Label: |
6C |
Detected: |
true |
Specimen Num: |
6 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3712215 |
Assay Type: |
RNA in situ |
Annotation Date: |
2007-06-21 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1752523 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:3712216 |
Age: |
embryonic day 15.0 |
Image: |
7A |
Note: |
Expression is in the specialized hair follicles around the eye and the nasal region. Higher magnification was shown in the inset. |
Specimen Label: |
7A |
Detected: |
true |
Specimen Num: |
8 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3712215 |
Assay Type: |
RNA in situ |
Annotation Date: |
2007-06-21 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1760523 |
Pattern: |
Not Specified |
Stage: |
TS23 |
Assay Id: |
MGI:3712216 |
Age: |
embryonic day 15.0 |
Image: |
7A |
|
Specimen Label: |
7A |
Detected: |
true |
Specimen Num: |
8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Moffatt P |
Year: |
2004 |
Journal: |
Gene |
Title: |
Identification of a conserved cluster of skin-specific genes encoding secreted proteins. |
Volume: |
334 |
|
Pages: |
123-31 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bazzi H |
Year: |
2007 |
Journal: |
Dev Dyn |
Title: |
Transcriptional profiling of developing mouse epidermis reveals novel patterns of coordinated gene expression. |
Volume: |
236 |
Issue: |
4 |
Pages: |
961-70 |
|
•
•
•
•
•
|
Publication |
First Author: |
Matsui T |
Year: |
2004 |
Journal: |
Genomics |
Title: |
Identification of novel keratinocyte-secreted peptides dermokine-alpha/-beta and a new stratified epithelium-secreted protein gene complex on human chromosome 19q13.1. |
Volume: |
84 |
Issue: |
2 |
Pages: |
384-97 |
|
•
•
•
•
•
|
Publication |
First Author: |
Takahashi Y |
Year: |
2000 |
Journal: |
Biochim Biophys Acta |
Title: |
Identification of cAMP analogue inducible genes in RAW264 macrophages. |
Volume: |
1492 |
Issue: |
2-3 |
Pages: |
385-94 |
|
•
•
•
•
•
|
Publication |
First Author: |
Jheon AH |
Year: |
2011 |
Journal: |
J Cell Sci |
Title: |
PERP regulates enamel formation via effects on cell-cell adhesion and gene expression. |
Volume: |
124 |
Issue: |
Pt 5 |
Pages: |
745-54 |
|
•
•
•
•
•
|
Publication |
First Author: |
Tang T |
Year: |
2010 |
Journal: |
Nat Biotechnol |
Title: |
A mouse knockout library for secreted and transmembrane proteins. |
Volume: |
28 |
Issue: |
7 |
Pages: |
749-55 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lexicon Genetics, Inc |
Year: |
2011 |
Journal: |
Database Download |
Title: |
MGI download of Lexicon knockout data |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Shanghai Model Organisms Center |
Year: |
2017 |
Journal: |
MGI Direct Data Submission |
Title: |
Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2002 |
|
Title: |
Function or Process or Component Unknown following Literature Review |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Magdaleno S |
Year: |
2006 |
Journal: |
PLoS Biol |
Title: |
BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system. |
Volume: |
4 |
Issue: |
4 |
Pages: |
e86 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2003 |
|
Title: |
MGI Sequence Curation Reference |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2002 |
|
Title: |
Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Kawai J |
Year: |
2001 |
Journal: |
Nature |
Title: |
Functional annotation of a full-length mouse cDNA collection. |
Volume: |
409 |
Issue: |
6821 |
Pages: |
685-90 |
|
•
•
•
•
•
|
Publication |
First Author: |
GemPharmatech |
Year: |
2020 |
|
Title: |
GemPharmatech Website. |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI) |
Year: |
2008 |
Journal: |
Database Download |
Title: |
Mouse Gene Trap Data Load from dbGSS |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
UniProt-GOA |
Year: |
2012 |
|
Title: |
Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Okazaki Y |
Year: |
2002 |
Journal: |
Nature |
Title: |
Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. |
Volume: |
420 |
Issue: |
6915 |
Pages: |
563-73 |
|
•
•
•
•
•
|
Publication |
First Author: |
Diez-Roux G |
Year: |
2011 |
Journal: |
PLoS Biol |
Title: |
A high-resolution anatomical atlas of the transcriptome in the mouse embryo. |
Volume: |
9 |
Issue: |
1 |
Pages: |
e1000582 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2002 |
|
Title: |
Mouse Genome Informatics Computational Sequence to Gene Associations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2). |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
MGI Genome Annotation Group and UniGene Staff |
Year: |
2015 |
Journal: |
Database Download |
Title: |
MGI-UniGene Interconnection Effort |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas |
Year: |
2010 |
|
Title: |
Annotation inferences using phylogenetic trees |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Database and National Center for Biotechnology Information |
Year: |
2000 |
Journal: |
Database Release |
Title: |
Entrez Gene Load |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI) |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Consensus CDS project |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Group |
Year: |
2003 |
Journal: |
Database Procedure |
Title: |
Automatic Encodes (AutoE) Reference |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Bairoch A |
Year: |
1999 |
Journal: |
Database Release |
Title: |
SWISS-PROT Annotated protein sequence database |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics |
Year: |
2010 |
Journal: |
Database Release |
Title: |
Protein Ontology Association Load. |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and loading genome assembly coordinates from NCBI annotations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform |
|
|
|
|
•
•
•
•
•
|
Allele |
Name: |
dermokine; endonuclease-mediated mutation 1, Shanghai Model Organisms Center |
Allele Type: |
Endonuclease-mediated |
Attribute String: |
Null/knockout |
|
•
•
•
•
•
|
Strain |
Attribute String: |
coisogenic, endonuclease-mediated mutation, mutant strain |
|
•
•
•
•
•
|
Allele |
Name: |
dermokine; targeted mutation 1, Minoru Hasegawa |
Allele Type: |
Targeted |
Attribute String: |
Conditional ready |
|
•
•
•
•
•
|
Allele |
Name: |
dermokine; targeted mutation 1.1, Minoru Hasegawa |
Allele Type: |
Targeted |
Attribute String: |
Modified isoform(s) |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
517
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
303
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
493
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
524
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
517
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
508
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Hasegawa M |
Year: |
2013 |
Journal: |
J Eur Acad Dermatol Venereol |
Title: |
Altered expression of dermokine in skin disorders. |
Volume: |
27 |
Issue: |
7 |
Pages: |
867-75 |
|
•
•
•
•
•
|
Publication |
First Author: |
Toulza E |
Year: |
2006 |
Journal: |
J Invest Dermatol |
Title: |
The human dermokine gene: description of novel isoforms with different tissue-specific expression and subcellular location. |
Volume: |
126 |
Issue: |
2 |
Pages: |
503-6 |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Family |
Description: |
Expression of the human dermokine gene (DMKN) leads to the production of four dermokine isoforms. Expression of the secreted alpha, beta and gamma isoforms is restricted to the epidermis []. DMKN beta and gamma are specifically expressed by the granular keratinocytes and have a role in cornification []. Dermokine levels are increased in inflammatory skin disorders, but decreased in skin cancers []. |
|
•
•
•
•
•
|
Allele |
Name: |
dermokine; endonuclease-mediated mutation 1, Minoru Hasegawa |
Allele Type: |
Endonuclease-mediated |
Attribute String: |
Modified isoform(s) |
|
•
•
•
•
•
|
Allele |
Name: |
dermokine; targeted mutation 1, Nathalie Jonca |
Allele Type: |
Targeted |
Attribute String: |
Modified isoform(s), Null/knockout |
|
•
•
•
•
•
|
Strain |
Attribute String: |
targeted mutation, mutant strain, congenic |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Dmkn/Dmkn |
Background: |
B6.129S2(Cg)-Dmkn |
Zygosity: |
hm |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Publication |
First Author: |
Fugmann T |
Year: |
2017 |
Journal: |
J Immunol |
Title: |
The MHC Class II Immunopeptidome of Lymph Nodes in Health and in Chemically Induced Colitis. |
Volume: |
198 |
Issue: |
3 |
Pages: |
1357-1364 |
|
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Publication |
First Author: |
Caldwell BA |
Year: |
2025 |
Journal: |
Sci Rep |
Title: |
Ticam2 ablation facilitates monocyte exhaustion recovery after sepsis. |
Volume: |
15 |
Issue: |
1 |
Pages: |
2059 |
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