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Search results 1 to 86 out of 86 for Dmkn

0.037s
Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: chimpanzee
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Publication
First Author: Leclerc EA
Year: 2014
Journal: J Cell Sci
Title: Mice deficient for the epidermal dermokine β and γ isoforms display transient cornification defects.
Volume: 127
Issue: Pt 13
Pages: 2862-72
Publication
First Author: Utsunomiya A
Year: 2020
Journal: J Invest Dermatol
Title: Homeostatic Function of Dermokine in the Skin Barrier and Inflammation.
Volume: 140
Issue: 4
Pages: 838-849.e9
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
GXD Expression    
Probe: MGI:3712215
Assay Type: RNA in situ
Annotation Date: 2007-06-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1654222
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:3712216
Age: embryonic day 14.0
Specimen Label: Not shown
Detected: true
Specimen Num: 9
GXD Expression
Probe: MGI:3712215
Assay Type: RNA in situ
Annotation Date: 2007-06-21
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1752823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:3712216
Age: embryonic day 15.5
Image: 2D
Note: Expression is in the suprabasal layers of the developing epidermis.
Specimen Label: 2D
Detected: true
Specimen Num: 1
GXD Expression
Probe: MGI:3712215
Assay Type: RNA in situ
Annotation Date: 2007-06-21
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1752823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:3712216
Age: embryonic day 15.5
Image: 2E
Note: Expression is in the suprabasal layers of the developing epidermis with less intense signals above the developing hair follicle placodes.
Specimen Label: 2E
Detected: true
Specimen Num: 2
GXD Expression
Probe: MGI:3712215
Assay Type: RNA in situ
Annotation Date: 2007-06-21
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1752823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:3712216
Age: embryonic day 15.5
Image: 2F
Note: Expression is in the suprabasal layers of the developing epidermis.
Specimen Label: 2F
Detected: true
Specimen Num: 3
GXD Expression
Probe: MGI:3712215
Assay Type: RNA in situ
Annotation Date: 2007-06-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1785022
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:3712216
Age: embryonic day 14.5
Image: 6A
Note: Higher magnification was shown in the inset.
Specimen Label: 6A
Detected: true
Specimen Num: 4
GXD Expression
Probe: MGI:3712215
Assay Type: RNA in situ
Annotation Date: 2007-06-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1785022
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:3712216
Age: embryonic day 15.0
Image: 6J,K
Note: Expression is in the stratifying nasal epithelium.
Specimen Label: 6J,K
Detected: true
Specimen Num: 7
GXD Expression
Probe: MGI:3712215
Assay Type: RNA in situ
Annotation Date: 2007-06-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1752523
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:3712216
Age: embryonic day 15.5
Image: 6B
Note: Expression is in larger areas of the skin as development progresses, it is absent in the scalp region.
Specimen Label: 6B
Detected: true
Specimen Num: 5
GXD Expression  
Probe: MGI:3712215
Assay Type: RNA in situ
Annotation Date: 2007-06-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1752524
Pattern: Uniform
Stage: TS24
Assay Id: MGI:3712216
Age: embryonic day 16.5
Image: 6C
Specimen Label: 6C
Detected: true
Specimen Num: 6
GXD Expression
Probe: MGI:3712215
Assay Type: RNA in situ
Annotation Date: 2007-06-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1752523
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:3712216
Age: embryonic day 15.0
Image: 7A
Note: Expression is in the specialized hair follicles around the eye and the nasal region. Higher magnification was shown in the inset.
Specimen Label: 7A
Detected: true
Specimen Num: 8
GXD Expression  
Probe: MGI:3712215
Assay Type: RNA in situ
Annotation Date: 2007-06-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1760523
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:3712216
Age: embryonic day 15.0
Image: 7A
Specimen Label: 7A
Detected: true
Specimen Num: 8
Publication  
First Author: Moffatt P
Year: 2004
Journal: Gene
Title: Identification of a conserved cluster of skin-specific genes encoding secreted proteins.
Volume: 334
Pages: 123-31
Publication
First Author: Bazzi H
Year: 2007
Journal: Dev Dyn
Title: Transcriptional profiling of developing mouse epidermis reveals novel patterns of coordinated gene expression.
Volume: 236
Issue: 4
Pages: 961-70
Publication
First Author: Matsui T
Year: 2004
Journal: Genomics
Title: Identification of novel keratinocyte-secreted peptides dermokine-alpha/-beta and a new stratified epithelium-secreted protein gene complex on human chromosome 19q13.1.
Volume: 84
Issue: 2
Pages: 384-97
Publication
First Author: Takahashi Y
Year: 2000
Journal: Biochim Biophys Acta
Title: Identification of cAMP analogue inducible genes in RAW264 macrophages.
Volume: 1492
Issue: 2-3
Pages: 385-94
Publication
First Author: Jheon AH
Year: 2011
Journal: J Cell Sci
Title: PERP regulates enamel formation via effects on cell-cell adhesion and gene expression.
Volume: 124
Issue: Pt 5
Pages: 745-54
Publication      
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
Publication
First Author: Tang T
Year: 2010
Journal: Nat Biotechnol
Title: A mouse knockout library for secreted and transmembrane proteins.
Volume: 28
Issue: 7
Pages: 749-55
Publication      
First Author: Lexicon Genetics, Inc
Year: 2011
Journal: Database Download
Title: MGI download of Lexicon knockout data
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Function or Process or Component Unknown following Literature Review
Publication
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
Publication
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
Publication      
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
Publication        
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2000
Title: Gene Ontology Annotation by electronic association of SwissProt Keywords with GO terms
Publication
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
Publication
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication      
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication        
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Allele
Name: dermokine; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
Allele
Name: dermokine; targeted mutation 1.1, Minoru Hasegawa
Allele Type: Targeted
Attribute String: Modified isoform(s)
Allele
Name: dermokine; targeted mutation 1, Minoru Hasegawa
Allele Type: Targeted
Attribute String: Conditional ready
Protein
Organism: Mus musculus/domesticus
Length: 517  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 303  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 493  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 524  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 517  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 508  
Fragment?: false
Publication
First Author: Hasegawa M
Year: 2013
Journal: J Eur Acad Dermatol Venereol
Title: Altered expression of dermokine in skin disorders.
Volume: 27
Issue: 7
Pages: 867-75
Publication
First Author: Toulza E
Year: 2006
Journal: J Invest Dermatol
Title: The human dermokine gene: description of novel isoforms with different tissue-specific expression and subcellular location.
Volume: 126
Issue: 2
Pages: 503-6
Protein Domain
Type: Family
Description: Expression of the human dermokine gene (DMKN) leads to the production of four dermokine isoforms. Expression of the secreted alpha, beta and gamma isoforms is restricted to the epidermis []. DMKN beta and gamma are specifically expressed by the granular keratinocytes and have a role in cornification []. Dermokine levels are increased in inflammatory skin disorders, but decreased in skin cancers [].
Allele
Name: dermokine; endonuclease-mediated mutation 1, Minoru Hasegawa
Allele Type: Endonuclease-mediated
Attribute String: Modified isoform(s)
Allele
Name: dermokine; targeted mutation 1, Nathalie Jonca
Allele Type: Targeted
Attribute String: Modified isoform(s), Null/knockout
Strain
Attribute String: targeted mutation, mutant strain, congenic
Genotype
Symbol: Dmkn/Dmkn
Background: B6.129S2(Cg)-Dmkn
Zygosity: hm
Has Mutant Allele: true
Publication
First Author: Fugmann T
Year: 2017
Journal: J Immunol
Title: The MHC Class II Immunopeptidome of Lymph Nodes in Health and in Chemically Induced Colitis.
Volume: 198
Issue: 3
Pages: 1357-1364