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Search results 1 to 100 out of 337 for Dmpk

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Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: zebrafish
Gene
Type: gene
Organism: frog, western clawed
Protein Domain
Type: Family
Description: This family consists of several bacterial phenol hydroxylase subunit proteins, which are part of a multicomponent phenol hydroxylase, including Phenol 2-monooxygenase, auxiliary component DmpK from Pseudomonas sp. DmpK may be involved in the post-translational incorporation of iron into theoxygenase component of the phenol hydroxylase []. Some bacteria can utilise phenol or some of its methylated derivatives as their sole source of carbon and energy. The first step in this process is the conversion of phenol into catechol. Catechol is then further metabolised via the meta-cleavage pathway into TCA cycle intermediates [].
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: chimpanzee
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
GXD Expression
Probe: MGI:2683161
Assay Type: RNA in situ
Annotation Date: 2004-01-07
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1774824
Pattern: Regionally restricted
Stage: TS24
Assay Id: MGI:2683257
Age: embryonic day 16.5
Image: 3, Dmpk
Note: Expression is in the muscles of the chest and lower back.
Specimen Label: 3, Dmpk
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:2683161
Assay Type: RNA in situ
Annotation Date: 2004-01-07
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1770124
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:2683257
Age: embryonic day 16.5
Image: 3, Dmpk
Specimen Label: 3, Dmpk
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:2683161
Assay Type: RNA in situ
Annotation Date: 2004-01-07
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1788324
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:2683257
Age: embryonic day 16.5
Image: 3, Dmpk
Specimen Label: 3, Dmpk
Detected: true
Specimen Num: 1
GXD Expression
Probe: MGI:2683161
Assay Type: RNA in situ
Annotation Date: 2004-01-07
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3287424
Pattern: Regionally restricted
Stage: TS24
Assay Id: MGI:2683257
Age: embryonic day 16.5
Image: 3, Dmpk
Note: Expression is in the muscles.
Specimen Label: 3, Dmpk
Detected: true
Specimen Num: 1
Publication
First Author: Powlowski J
Year: 1997
Journal: J Biol Chem
Title: On the role of DmpK, an auxiliary protein associated with multicomponent phenol hydroxylase from Pseudomonas sp. strain CF600.
Volume: 272
Issue: 2
Pages: 945-51
Publication
First Author: Herrmann H
Year: 1995
Journal: Mol Gen Genet
Title: Localization and organization of phenol degradation genes of Pseudomonas putida strain H.
Volume: 247
Issue: 2
Pages: 240-6
Publication
First Author: Michel L
Year: 2015
Journal: PLoS One
Title: Sense and Antisense DMPK RNA Foci Accumulate in DM1 Tissues during Development.
Volume: 10
Issue: 9
Pages: e0137620
Publication
First Author: Berul CI
Year: 1999
Journal: J Clin Invest
Title: DMPK dosage alterations result in atrioventricular conduction abnormalities in a mouse myotonic dystrophy model.
Volume: 103
Issue: 4
Pages: R1-7
Publication
First Author: Pall GS
Year: 2003
Journal: Physiol Genomics
Title: Abnormal contractile activity and calcium cycling in cardiac myocytes isolated from DMPK knockout mice.
Volume: 13
Issue: 2
Pages: 139-46
Publication
First Author: Carrell ST
Year: 2016
Journal: Hum Mol Genet
Title: Dmpk gene deletion or antisense knockdown does not compromise cardiac or skeletal muscle function in mice.
Volume: 25
Issue: 19
Pages: 4328-4338
Publication
First Author: Orengo JP
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: Expanded CTG repeats within the DMPK 3' UTR causes severe skeletal muscle wasting in an inducible mouse model for myotonic dystrophy.
Volume: 105
Issue: 7
Pages: 2646-51
Publication
First Author: van Herpen RE
Year: 2005
Journal: Mol Cell Biol
Title: Divergent mitochondrial and endoplasmic reticulum association of DMPK splice isoforms depends on unique sequence arrangements in tail anchors.
Volume: 25
Issue: 4
Pages: 1402-14
Gene
Type: gene
Organism: human
Publication
First Author: O'Cochlain DF
Year: 2004
Journal: Hum Mol Genet
Title: Transgenic overexpression of human DMPK accumulates into hypertrophic cardiomyopathy, myotonic myopathy and hypotension traits of myotonic dystrophy.
Volume: 13
Issue: 20
Pages: 2505-18
Publication
First Author: Matynia A
Year: 2010
Journal: PLoS One
Title: Muscleblind1, but not Dmpk or Six5, contributes to a complex phenotype of muscular and motivational deficits in mouse models of myotonic dystrophy.
Volume: 5
Issue: 3
Pages: e9857
Publication
First Author: Yadava RS
Year: 2020
Journal: Hum Mol Genet
Title: Systemic therapy in an RNA toxicity mouse model with an antisense oligonucleotide therapy targeting a non-CUG sequence within the DMPK 3'UTR RNA.
Volume: 29
Issue: 9
Pages: 1440-1453
Publication
First Author: Guiraud-Dogan C
Year: 2007
Journal: Biochim Biophys Acta
Title: DM1 CTG expansions affect insulin receptor isoforms expression in various tissues of transgenic mice.
Volume: 1772
Issue: 11-12
Pages: 1183-91
Publication  
First Author: Rao AN
Year: 2021
Journal: JCI Insight
Title: Reversible cardiac disease features in an inducible CUG repeat RNA-expressing mouse model of myotonic dystrophy.
Volume: 6
Issue: 5
Publication
First Author: Morriss GR
Year: 2018
Journal: Hum Mol Genet
Title: Mechanisms of skeletal muscle wasting in a mouse model for myotonic dystrophy type 1.
Volume: 27
Issue: 16
Pages: 2789-2804
Publication
First Author: Seznec H
Year: 2001
Journal: Hum Mol Genet
Title: Mice transgenic for the human myotonic dystrophy region with expanded CTG repeats display muscular and brain abnormalities.
Volume: 10
Issue: 23
Pages: 2717-26
Publication
First Author: Llagostera E
Year: 2009
Journal: FEBS Lett
Title: High-fat diet induced adiposity and insulin resistance in mice lacking the myotonic dystrophy protein kinase.
Volume: 583
Issue: 12
Pages: 2121-5
Publication
First Author: Reddy S
Year: 2002
Journal: Muscle Nerve
Title: Effects of age and gene dose on skeletal muscle sodium channel gating in mice deficient in myotonic dystrophy protein kinase.
Volume: 25
Issue: 6
Pages: 850-7
Publication
First Author: Nutter CA
Year: 2019
Journal: Genes Dev
Title: Cell-type-specific dysregulation of RNA alternative splicing in short tandem repeat mouse knockin models of myotonic dystrophy.
Volume: 33
Issue: 23-24
Pages: 1635-1640
Publication
First Author: Mankodi A
Year: 2000
Journal: Science
Title: Myotonic dystrophy in transgenic mice expressing an expanded CUG repeat.
Volume: 289
Issue: 5485
Pages: 1769-73
Publication
First Author: Reddy S
Year: 1996
Journal: Nat Genet
Title: Mice lacking the myotonic dystrophy protein kinase develop a late onset progressive myopathy.
Volume: 13
Issue: 3
Pages: 325-35
Publication
First Author: Harmon EB
Year: 2008
Journal: Dev Dyn
Title: Myotonic dystrophy protein kinase is expressed in embryonic myocytes and is required for myotube formation.
Volume: 237
Issue: 9
Pages: 2353-66
Publication
First Author: Jansen G
Year: 1996
Journal: Nat Genet
Title: Abnormal myotonic dystrophy protein kinase levels produce only mild myopathy in mice.
Volume: 13
Issue: 3
Pages: 316-24
Publication
First Author: van den Broek WJ
Year: 2006
Journal: FEBS Lett
Title: Fen1 does not control somatic hypermutability of the (CTG)(n)*(CAG)(n) repeat in a knock-in mouse model for DM1.
Volume: 580
Issue: 22
Pages: 5208-14
Publication
First Author: Benders AA
Year: 1997
Journal: J Clin Invest
Title: Myotonic dystrophy protein kinase is involved in the modulation of the Ca2+ homeostasis in skeletal muscle cells.
Volume: 100
Issue: 6
Pages: 1440-7
Publication
First Author: Groenen PJ
Year: 2000
Journal: Hum Mol Genet
Title: Constitutive and regulated modes of splicing produce six major myotonic dystrophy protein kinase (DMPK) isoforms with distinct properties.
Volume: 9
Issue: 4
Pages: 605-16
Publication
First Author: Schulz PE
Year: 2003
Journal: J Neurophysiol
Title: A role for myotonic dystrophy protein kinase in synaptic plasticity.
Volume: 89
Issue: 3
Pages: 1177-86
Publication
First Author: Kaliman P
Year: 2005
Journal: J Biol Chem
Title: Myotonic dystrophy protein kinase phosphorylates phospholamban and regulates calcium uptake in cardiomyocyte sarcoplasmic reticulum.
Volume: 280
Issue: 9
Pages: 8016-21
Publication
First Author: Harmon EB
Year: 2011
Journal: J Biol Chem
Title: Myotonic dystrophy protein kinase is critical for nuclear envelope integrity.
Volume: 286
Issue: 46
Pages: 40296-306
Publication
First Author: Llagostera E
Year: 2007
Journal: PLoS One
Title: Role of myotonic dystrophy protein kinase (DMPK) in glucose homeostasis and muscle insulin action.
Volume: 2
Issue: 11
Pages: e1134
Publication
First Author: Mounsey JP
Year: 2000
Journal: Hum Mol Genet
Title: Skeletal muscle sodium channel gating in mice deficient in myotonic dystrophy protein kinase.
Volume: 9
Issue: 15
Pages: 2313-20
Publication
First Author: Carrasco M
Year: 2002
Journal: Endocrinology
Title: Identification of intracellular signaling pathways that induce myotonic dystrophy protein kinase expression during myogenesis.
Volume: 143
Issue: 8
Pages: 3017-25
Publication
First Author: Tomé S
Year: 2011
Journal: Hum Mol Genet
Title: Maternal germline-specific effect of DNA ligase I on CTG/CAG instability.
Volume: 20
Issue: 11
Pages: 2131-43
Publication
First Author: Kanadia RN
Year: 2003
Journal: Gene Expr Patterns
Title: Developmental expression of mouse muscleblind genes Mbnl1, Mbnl2 and Mbnl3.
Volume: 3
Issue: 4
Pages: 459-62
Publication
First Author: Mistry DJ
Year: 2001
Journal: Physiol Genomics
Title: Skeletal muscle Na currents in mice heterozygous for Six5 deficiency.
Volume: 6
Issue: 3
Pages: 153-8
Publication
First Author: Boucher CA
Year: 1995
Journal: Hum Mol Genet
Title: A novel homeodomain-encoding gene is associated with a large CpG island interrupted by the myotonic dystrophy unstable (CTG)n repeat.
Volume: 4
Issue: 10
Pages: 1919-25
Publication
First Author: Lee HC
Year: 2003
Journal: Physiol Genomics
Title: Abnormal Na channel gating in murine cardiac myocytes deficient in myotonic dystrophy protein kinase.
Volume: 12
Issue: 2
Pages: 147-57
Publication
First Author: Laurent A
Year: 1997
Journal: Cell Mol Biol (Noisy-le-grand)
Title: Expression of myotonic dystrophy protein kinase gene during in vivo and in vitro mouse myogenesis.
Volume: 43
Issue: 6
Pages: 881-8
Publication
First Author: Christou M
Year: 2020
Journal: Nucleic Acid Ther
Title: Systemic Evaluation of Chimeric LNA/2'-O-Methyl Steric Blockers for Myotonic Dystrophy Type 1 Therapy.
Volume: 30
Issue: 2
Pages: 80-93
Publication
First Author: Gladman JT
Year: 2013
Journal: PLoS One
Title: Age of onset of RNA toxicity influences phenotypic severity: evidence from an inducible mouse model of myotonic dystrophy (DM1).
Volume: 8
Issue: 9
Pages: e72907
Publication      
First Author: Nutter CA
Year: 2023
Journal: Brain
Title: Choroid plexus mis-splicing and altered cerebrospinal fluid composition in myotonic dystrophy type 1.
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Jansen G
Year: 1992
Journal: Nat Genet
Title: Characterization of the myotonic dystrophy region predicts multiple protein isoform-encoding mRNAs.
Volume: 1
Issue: 4
Pages: 261-6
Publication
First Author: Mahadevan MS
Year: 1993
Journal: Hum Mol Genet
Title: Structure and genomic sequence of the myotonic dystrophy (DM kinase) gene.
Volume: 2
Issue: 3
Pages: 299-304
Publication
First Author: Saba S
Year: 1999
Journal: J Cardiovasc Electrophysiol
Title: Localization of the sites of conduction abnormalities in a mouse model of myotonic dystrophy.
Volume: 10
Issue: 9
Pages: 1214-20
Publication  
First Author: van den Broek WJ
Year: 2007
Journal: BMC Mol Biol
Title: Somatic CTG*CAG repeat instability in a mouse model for myotonic dystrophy type 1 is associated with changes in cell nuclearity and DNA ploidy.
Volume: 8
Pages: 61
Publication
First Author: Fu YH
Year: 1996
Journal: Genetica
Title: Identification of a novel protein, DMAP, which interacts with the myotonic dystrophy protein kinase and shows strong homology to D1 snRNP.
Volume: 97
Issue: 1
Pages: 117-25
Publication
First Author: Shaw DJ
Year: 1993
Journal: Genomics
Title: Genomic organization and transcriptional units at the myotonic dystrophy locus.
Volume: 18
Issue: 3
Pages: 673-9
Publication
First Author: Zhang Y
Year: 2002
Journal: Hum Mol Genet
Title: Age and insertion site dependence of repeat number instability of a human DM1 transgene in individual mouse sperm.
Volume: 11
Issue: 7
Pages: 791-8
Publication
First Author: Lazarski CA
Year: 2006
Journal: J Exp Med
Title: The impact of DM on MHC class II-restricted antigen presentation can be altered by manipulation of MHC-peptide kinetic stability.
Volume: 203
Issue: 5
Pages: 1319-28
GXD Expression      
Probe: MGI:2680672
Assay Type: RNase protection
Annotation Date: 2003-12-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3598827
Stage: TS27
Assay Id: MGI:2680679
Age: postnatal newborn
Specimen Label: 1
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:2680672
Assay Type: RNase protection
Annotation Date: 2003-12-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3598828
Stage: TS28
Assay Id: MGI:2680679
Age: postnatal week 3
Specimen Label: 2
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:2680672
Assay Type: RNase protection
Annotation Date: 2003-12-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3598828
Stage: TS28
Assay Id: MGI:2680679
Age: postnatal month 2
Specimen Label: 3
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:2680672
Assay Type: RNase protection
Annotation Date: 2003-12-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3598828
Stage: TS28
Assay Id: MGI:2680679
Age: postnatal week 2
Specimen Label: 4
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:2680672
Assay Type: RNase protection
Annotation Date: 2003-12-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3598828
Stage: TS28
Assay Id: MGI:2680679
Age: postnatal month 2
Specimen Label: 5
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:2680672
Assay Type: RNase protection
Annotation Date: 2003-12-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3598828
Stage: TS28
Assay Id: MGI:2680679
Age: postnatal month 2
Specimen Label: 6
Detected: true
Specimen Num: 6
GXD Expression      
Probe: MGI:2680672
Assay Type: RNase protection
Annotation Date: 2003-12-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3598828
Stage: TS28
Assay Id: MGI:2680679
Age: postnatal week 3
Specimen Label: 7
Detected: true
Specimen Num: 7
GXD Expression      
Probe: MGI:2680672
Assay Type: RNase protection
Annotation Date: 2003-12-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3598828
Stage: TS28
Assay Id: MGI:2680679
Age: postnatal week 3
Specimen Label: 8
Detected: true
Specimen Num: 8
GXD Expression      
Probe: MGI:2680672
Assay Type: RNase protection
Annotation Date: 2003-12-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3598828
Stage: TS28
Assay Id: MGI:2680680
Age: postnatal week 3
Specimen Label: 1
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:2680672
Assay Type: RNase protection
Annotation Date: 2003-12-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3598828
Stage: TS28
Assay Id: MGI:2680680
Age: postnatal week 2
Specimen Label: 2
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:2680672
Assay Type: RNase protection
Annotation Date: 2003-12-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3598826
Stage: TS26
Assay Id: MGI:2680680
Age: embryonic day 19.0
Specimen Label: 3
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:2680672
Assay Type: RNase protection
Annotation Date: 2003-12-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3598824
Stage: TS24
Assay Id: MGI:2680680
Age: embryonic day 16.5
Specimen Label: 4
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:2681129
Assay Type: RT-PCR
Annotation Date: 2003-12-12
Strength: Present
Sex: Male
Emaps: EMAPS:3598828
Stage: TS28
Assay Id: MGI:2681134
Age: postnatal month 4
Specimen Label: 2
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:2681129
Assay Type: RT-PCR
Annotation Date: 2003-12-12
Strength: Present
Sex: Male
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:2681134
Age: postnatal month 4
Specimen Label: 3
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:2681129
Assay Type: RT-PCR
Annotation Date: 2003-12-12
Strength: Present
Sex: Male
Emaps: EMAPS:3271728
Stage: TS28
Assay Id: MGI:2681134
Age: postnatal month 4
Specimen Label: 4
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:2681129
Assay Type: RT-PCR
Annotation Date: 2003-12-12
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:2681134
Age: postnatal month 4
Specimen Label: 5
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:2681129
Assay Type: RT-PCR
Annotation Date: 2003-12-12
Strength: Present
Sex: Male
Emaps: EMAPS:1876828
Stage: TS28
Assay Id: MGI:2681134
Age: postnatal month 4
Specimen Label: 6
Detected: true
Specimen Num: 6
GXD Expression      
Probe: MGI:2681129
Assay Type: RT-PCR
Annotation Date: 2003-12-12
Strength: Present
Sex: Male
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:2681134
Age: postnatal month 4
Specimen Label: 7
Detected: true
Specimen Num: 7