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Search results 1 to 100 out of 103 for Dnaaf1

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Categories

Hits by Strain

Hits by Category

Type Details Score
Gene
123872 | DNAAF1
Type: gene
Organism: human
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Gene
523187 | DNAAF1
Type: gene
Organism: cattle
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Gene
415702 | DNAAF1
Type: gene
Organism: chicken
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Gene
386722 | dnaaf1
Type: gene
Organism: zebrafish
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Gene
715137 | DNAAF1
Type: gene
Organism: macaque, rhesus
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Gene
101730543 | dnaaf1
Type: gene
Organism: frog, western clawed
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Gene
361419 | Dnaaf1
Type: gene
Organism: rat
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Gene
479628 | DNAAF1
Type: gene
Organism: dog, domestic
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Gene
454277 | DNAAF1
Type: gene
Organism: chimpanzee
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Protein Domain
IPR027734 | DNAAF1
Type: Family
Description: Dynein assembly factor 1 (also known as LRRC50) is a cilium-specific protein involved in the cytoplasmic preassembly of dynein arms []. Its homologue in Chlamydomonas, known as ODA7, serves as a structural link between inner and outer row dyneins []. Defects in the LRRC50 gene are the cause of primary ciliary dyskinesia type 13 (CILD13), which is a disorder characterised by abnormalities of motile cilia [], leading to respiratory infections and reduced male fertility. Aberrations in the gene may also be implicated in cystic kidney disease [].
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Protein Coding Gene
MGI:1915520 | Dnaaf1
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
19944400 | J:158467
First Author: Loges NT
Year: 2009
Journal: Am J Hum Genet
Title: Deletions and point mutations of LRRC50 cause primary ciliary dyskinesia due to dynein arm defects.
Volume: 85
Issue: 6
Pages: 883-9
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Publication
27261005 | J:240195
First Author: Ha S
Year: 2016
Journal: G3 (Bethesda)
Title: Mutations in Dnaaf1 and Lrrc48 Cause Hydrocephalus, Laterality Defects, and Sinusitis in Mice.
Volume: 6
Issue: 8
Pages: 2479-87
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Protein
Q9D2H9
Organism: Mus musculus/domesticus
Length: 634  
Fragment?: false
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Publication
18385425 | -
First Author: van Rooijen E
Year: 2008
Journal: J Am Soc Nephrol
Title: LRRC50, a conserved ciliary protein implicated in polycystic kidney disease.
Volume: 19
Issue: 6
Pages: 1128-38
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Publication
17194703 | -
First Author: Freshour J
Year: 2007
Journal: J Biol Chem
Title: Chlamydomonas flagellar outer row dynein assembly protein ODA7 interacts with both outer row and I1 inner row dyneins.
Volume: 282
Issue: 8
Pages: 5404-12
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Protein Coding Gene
MGP_CAROLIEiJ_G0031622 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0034186 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0034166 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0034093 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0034160 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0033871 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_1915520 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0034680 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0033198 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0033844 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0034000 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0033943 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0034089 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0033990 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0034698 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0032900 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0033314 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0023220 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0032740 | -
Type: protein_coding_gene
Organism: Mus spretus
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GXD Expression
GXD Expression
     
Probe: MGI:6386798
Assay Type: RT-PCR
Annotation Date: 2020-01-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:6386805
Age: postnatal adult
Specimen Label: Spleen
Detected: true
Specimen Num: 8
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GXD Expression
GXD Expression
     
Probe: MGI:6386798
Assay Type: RT-PCR
Annotation Date: 2020-01-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:6386805
Age: postnatal adult
Specimen Label: Kidney
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
     
Probe: MGI:6386798
Assay Type: RT-PCR
Annotation Date: 2020-01-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:6386810
Age: postnatal adult
Specimen Label: Kidney
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
     
Probe: MGI:6386798
Assay Type: RT-PCR
Annotation Date: 2020-01-29
Strength: Present
Sex: Female
Emaps: EMAPS:1898428
Stage: TS28
Assay Id: MGI:6386805
Age: postnatal adult
Specimen Label: Oviduct
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
     
Probe: MGI:6156776
Assay Type: RT-PCR
Annotation Date: 2018-05-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672826
Stage: TS26
Assay Id: MGI:6157643
Age: embryonic day 18.5
Specimen Label: Sample 2 WT
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
     
Probe: MGI:6156776
Assay Type: RT-PCR
Annotation Date: 2018-05-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672826
Stage: TS26
Assay Id: MGI:6157643
Age: embryonic day 18.5
Specimen Label: Sample 2 Foxj1-/-
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
     
Probe: MGI:6156776
Assay Type: RT-PCR
Annotation Date: 2018-05-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672826
Stage: TS26
Assay Id: MGI:6157643
Age: embryonic day 18.5
Specimen Label: Sample 1 WT
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:6156776
Assay Type: RT-PCR
Annotation Date: 2018-05-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672826
Stage: TS26
Assay Id: MGI:6157643
Age: embryonic day 18.5
Specimen Label: Sample 1 Foxj1-/-
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:6386798
Assay Type: RT-PCR
Annotation Date: 2020-01-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672828
Stage: TS28
Assay Id: MGI:6386805
Age: postnatal adult
Specimen Label: Lung
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
     
Probe: MGI:6386798
Assay Type: RT-PCR
Annotation Date: 2020-01-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:6386805
Age: postnatal adult
Specimen Label: Heart
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:6156776
Assay Type: RT-PCR
Annotation Date: 2018-05-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603911
Stage: TS11
Assay Id: MGI:6157769
Age: embryonic day 7.5-8.0
Specimen Label: Noto heterozygous
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:6156776
Assay Type: RT-PCR
Annotation Date: 2018-05-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603912
Stage: TS12
Assay Id: MGI:6157769
Age: embryonic day 7.5-8.0
Specimen Label: Noto heterozygous
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:6156776
Assay Type: RT-PCR
Annotation Date: 2018-05-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603911
Stage: TS11
Assay Id: MGI:6157769
Age: embryonic day 7.5-8.0
Specimen Label: Noto homozygous
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:6156776
Assay Type: RT-PCR
Annotation Date: 2018-05-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603912
Stage: TS12
Assay Id: MGI:6157769
Age: embryonic day 7.5-8.0
Specimen Label: Noto homozygous
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:6386798
Assay Type: RT-PCR
Annotation Date: 2020-01-29
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:160399
Stage: TS09
Assay Id: MGI:6386810
Age: embryonic day 6.5
Specimen Label: E6.5 C57BL/6N
Detected: false
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:6386798
Assay Type: RT-PCR
Annotation Date: 2020-01-29
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:160399
Stage: TS09
Assay Id: MGI:6386810
Age: embryonic day 6.5
Specimen Label: E6.5 ICR
Detected: false
Specimen Num: 3
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GXD Expression
GXD Expression
       
Probe: MGI:6386798
Assay Type: RT-PCR
Annotation Date: 2020-01-29
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1603911
Stage: TS11
Assay Id: MGI:6386810
Age: embryonic day 7.5
Specimen Label: E7.5
Specimen Num: 4
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GXD Expression
GXD Expression
       
Probe: MGI:6386798
Assay Type: RT-PCR
Annotation Date: 2020-01-29
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1603913
Stage: TS13
Assay Id: MGI:6386810
Age: embryonic day 8.5
Specimen Label: E8.5
Specimen Num: 5
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GXD Expression
GXD Expression
       
Probe: MGI:6386798
Assay Type: RT-PCR
Annotation Date: 2020-01-29
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1603915
Stage: TS15
Assay Id: MGI:6386810
Age: embryonic day 9.5
Specimen Label: E9.5
Specimen Num: 6
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GXD Expression
GXD Expression
     
Probe: MGI:6386798
Assay Type: RT-PCR
Annotation Date: 2020-01-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:6386805
Age: postnatal adult
Specimen Label: Liver
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
     
Probe: MGI:6386798
Assay Type: RT-PCR
Annotation Date: 2020-01-29
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:360354
Stage: TS04
Assay Id: MGI:6386810
Age: embryonic day 3.5
Specimen Label: E3.5
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:5911971
Assay Type: Western blot
Annotation Date: 2017-10-31
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:5912094
Age: postnatal adult
Image: 6
Specimen Label: Input
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:6386798
Assay Type: RT-PCR
Annotation Date: 2020-01-29
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:6386805
Age: postnatal adult
Specimen Label: Testis
Detected: true
Specimen Num: 9
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GXD Expression
GXD Expression
     
Probe: MGI:6386798
Assay Type: RT-PCR
Annotation Date: 2020-01-29
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:6386810
Age: postnatal adult
Specimen Label: Testis
Detected: true
Specimen Num: 8
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GXD Expression
GXD Expression
     
Probe: MGI:6386798
Assay Type: RT-PCR
Annotation Date: 2020-01-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:6386805
Age: postnatal adult
Specimen Label: Brain
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:6386798
Assay Type: RT-PCR
Annotation Date: 2020-01-29
Strength: Present
Sex: Female
Emaps: EMAPS:1796228
Stage: TS28
Assay Id: MGI:6386805
Age: postnatal adult
Specimen Label: Ovary
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
     
Probe: MGI:4453637
Assay Type: RNA in situ
Annotation Date: 2010-05-29
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:4453640
Age: postnatal adult
Specimen Label: Not shown
Detected: false
Specimen Num: 7
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GXD Expression
GXD Expression
   
Probe: MGI:4453637
Assay Type: RNA in situ
Annotation Date: 2010-05-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1607512
Pattern: Not Specified
Stage: TS12
Assay Id: MGI:4453640
Age: embryonic day 7.75
Specimen Label: 3B
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:4453637
Assay Type: RNA in situ
Annotation Date: 2010-05-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1607512
Pattern: Not Specified
Stage: TS12
Assay Id: MGI:4453640
Age: embryonic day 8.0
Specimen Label: 3C
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
     
Probe: MGI:4453637
Assay Type: RNA in situ
Annotation Date: 2010-05-29
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1607511
Stage: TS11
Assay Id: MGI:4453640
Age: embryonic day 7.5
Specimen Label: 3A
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:4453637
Assay Type: RNA in situ
Annotation Date: 2010-05-29
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1607513
Stage: TS13
Assay Id: MGI:4453640
Age: embryonic day 8.5
Specimen Label: 3D
Detected: false
Specimen Num: 4
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GXD Expression
GXD Expression
 
Probe: MGI:4453637
Assay Type: RNA in situ
Annotation Date: 2010-05-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1760724
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:4453640
Age: embryonic day 16.5
Note: Expression is in ciliated cells.
Specimen Label: 3F
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
 
Probe: MGI:4453637
Assay Type: RNA in situ
Annotation Date: 2010-05-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1767224
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:4453640
Age: embryonic day 16.5
Note: Expression is in ciliated cells.
Specimen Label: 3E
Detected: true
Specimen Num: 5
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Publication
23968836 | J:199782
First Author: Ha S
Year: 2015
Journal: Cereb Cortex
Title: A forward genetic screen in mice identifies mutants with abnormal cortical patterning.
Volume: 25
Issue: 1
Pages: 167-79
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Publication
18689890 | J:139579
First Author: Turner LM
Year: 2008
Journal: Genetics
Title: Comparative analysis of testis protein evolution in rodents.
Volume: 179
Issue: 4
Pages: 2075-89
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Publication
24421334 | J:208266
First Author: Dong F
Year: 2014
Journal: J Cell Biol
Title: Pih1d3 is required for cytoplasmic preassembly of axonemal dynein in mouse sperm.
Volume: 204
Issue: 2
Pages: 203-13
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Publication
31107948 | J:278736
First Author: Cheong A
Year: 2019
Journal: Hum Mol Genet
Title: A null allele of Dnaaf2 displays embryonic lethality and mimics human ciliary dyskinesia.
Volume: 28
Issue: 16
Pages: 2775-2784
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Publication
27914912 | J:240319
First Author: Stauber M
Year: 2017
Journal: Dev Biol
Title: Identification of FOXJ1 effectors during ciliogenesis in the foetal respiratory epithelium and embryonic left-right organiser of the mouse.
Volume: 423
Issue: 2
Pages: 170-188
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Publication
- | J:188991
     
First Author: The Jackson Laboratory
Year: 2012
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by The Jackson Laboratory
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Publication
- | J:211773
     
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
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Publication
18799693 | J:142754
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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Publication
- | J:78475
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
38355793 | J:345621
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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