|  Help  |  About  |  Contact Us

Search our database by keyword

Examples

  • Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
  • Use OR to search for either of two terms (e.g. OR mus) or quotation marks to search for phrases (e.g. "dna binding").
  • Boolean search syntax is supported: e.g. Balb* for partial matches or mus AND NOT embryo to exclude a term

Search results 1 to 100 out of 101 for Dnah9

<< First    < Previous  |  Next >    Last >>
0.039s
Type Details Score
Gene
Type: gene
Organism: Homo sapiens
Gene
Type: gene
Organism: Rattus norvegicus
Gene
Type: gene
Organism: Danio rerio
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Domain
Type: Family
Description: Dyneins are described as motor proteins of eukaryotic cells, as they can convert energy derived from the hydrolysis of ATP to force and movement along cytoskeletal polymers, such as microtubules. Dyneins generally contain one to three heavy chains, where each heavy chain consists of a C-terminal globular head, a flexible microtubule-binding stalk, and a flexible N-terminal tail known as the cargo-binding domain []. The two categories of dyneins are the axonemal dyneins, which produce the bending motions that propagate along cilia and flagella, and the cytosolic dyneins, which drive a variety of fundamental cellular processes including nuclear migration, organisation of the mitotic spindle, chromosome separation during mitosis, and the positioning and function of many intracellular organelles. Cytoplasmic dyneins contain several accessory subunits ranging from light to intermediate chains.DNAH9 (dynein axonemal heavy chain 9) is involved in respiratory cilia mobility and associated with primary ciliary dyskinesia, a disease associated with abnormalities of pulmonary function []. It produces force towards the minus ends of microtubules, thought to occur on release of ADP.
Publication
First Author: Dizier MH
Year: 2016
Journal: Eur Respir J
Title: Interaction between the DNAH9 gene and early smoke exposure in bronchial hyperresponsiveness.
Volume: 47
Issue: 4
Pages: 1072-81
Protein
Organism: Mus musculus
Length: 4484  
Fragment?: false
Protein
Organism: Mus musculus
Length: 1471  
Fragment?: true
Protein
Organism: Mus musculus
Length: 1958  
Fragment?: true
Protein
Organism: Mus musculus
Length: 1957  
Fragment?: true
Protein
Organism: Mus musculus
Length: 279  
Fragment?: true
Protein
Organism: Mus musculus
Length: 457  
Fragment?: false
Publication
First Author: Oiwa K
Year: 2005
Journal: Curr Opin Cell Biol
Title: Recent progress in dynein structure and mechanism.
Volume: 17
Issue: 1
Pages: 98-103
Publication
First Author: Inaba Y
Year: 2016
Journal: Genes Cells
Title: Transport of the outer dynein arm complex to cilia requires a cytoplasmic protein Lrrc6.
Volume: 21
Issue: 7
Pages: 728-39
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
GXD Expression    
Probe: MGI:5911969
Assay Type: Western blot
Annotation Date: 2017-10-31
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:5912080
Age: postnatal adult
Image: 5
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:5911969
Assay Type: Western blot
Annotation Date: 2017-10-31
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:5912080
Age: postnatal adult
Image: 5
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:5911969
Assay Type: Western blot
Annotation Date: 2017-10-31
Strength: Present
Sex: Male
Emaps: EMAPS:3148828
Stage: TS28
Assay Id: MGI:5912046
Age: postnatal adult
Image: 5
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:5911969
Assay Type: Western blot
Annotation Date: 2017-10-31
Strength: Present
Sex: Male
Emaps: EMAPS:3148828
Stage: TS28
Assay Id: MGI:5912046
Age: postnatal adult
Image: 5
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:4423298
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1757823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824342
Age: embryonic day 14.5
Image: euxassay_010961_16
Detected: true
Specimen Num: 13
GXD Expression  
Probe: MGI:4423298
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1757823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824342
Age: embryonic day 14.5
Image: euxassay_010961_15
Detected: true
Specimen Num: 12
GXD Expression  
Probe: MGI:4423298
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1757823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824342
Age: embryonic day 14.5
Image: euxassay_010961_14
Detected: true
Specimen Num: 11
GXD Expression  
Probe: MGI:4423298
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1757823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824342
Age: embryonic day 14.5
Image: euxassay_010961_13
Detected: true
Specimen Num: 10
GXD Expression  
Probe: MGI:4423298
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1725823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824342
Age: embryonic day 14.5
Image: euxassay_010961_12
Detected: true
Specimen Num: 9
GXD Expression  
Probe: MGI:4423298
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1754823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824342
Age: embryonic day 14.5
Image: euxassay_010961_19
Detected: true
Specimen Num: 16
GXD Expression  
Probe: MGI:4423298
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1754823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824342
Age: embryonic day 14.5
Image: euxassay_010961_18
Detected: true
Specimen Num: 15
GXD Expression  
Probe: MGI:4423298
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1754823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824342
Age: embryonic day 14.5
Image: euxassay_010961_17
Detected: true
Specimen Num: 14
GXD Expression  
Probe: MGI:4423298
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1754823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824342
Age: embryonic day 14.5
Image: euxassay_010961_16
Detected: true
Specimen Num: 13
GXD Expression  
Probe: MGI:4423298
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1754823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824342
Age: embryonic day 14.5
Image: euxassay_010961_12
Detected: true
Specimen Num: 9
GXD Expression  
Probe: MGI:4423298
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1754823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824342
Age: embryonic day 14.5
Image: euxassay_010961_11
Detected: true
Specimen Num: 8
GXD Expression  
Probe: MGI:4423298
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1754823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824342
Age: embryonic day 14.5
Image: euxassay_010961_10
Detected: true
Specimen Num: 7
GXD Expression  
Probe: MGI:4423298
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1754823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824342
Age: embryonic day 14.5
Image: euxassay_010961_09
Detected: true
Specimen Num: 6
GXD Expression  
Probe: MGI:4423298
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1754823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824342
Age: embryonic day 14.5
Image: euxassay_010961_08
Detected: true
Specimen Num: 5
GXD Expression  
Probe: MGI:4423298
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1754823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824342
Age: embryonic day 14.5
Image: euxassay_010961_07
Detected: true
Specimen Num: 4
GXD Expression  
Probe: MGI:4423298
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1690923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824342
Age: embryonic day 14.5
Image: euxassay_010961_15
Detected: true
Specimen Num: 12
GXD Expression  
Probe: MGI:4423298
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1690923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824342
Age: embryonic day 14.5
Image: euxassay_010961_14
Detected: true
Specimen Num: 11
GXD Expression  
Probe: MGI:4423298
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1756823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824342
Age: embryonic day 14.5
Image: euxassay_010961_22
Detected: true
Specimen Num: 19
GXD Expression  
Probe: MGI:4423298
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1756823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824342
Age: embryonic day 14.5
Image: euxassay_010961_21
Detected: true
Specimen Num: 18
GXD Expression  
Probe: MGI:4423298
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1756823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824342
Age: embryonic day 14.5
Image: euxassay_010961_20
Detected: true
Specimen Num: 17
GXD Expression  
Probe: MGI:4423298
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1756823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824342
Age: embryonic day 14.5
Image: euxassay_010961_19
Detected: true
Specimen Num: 16
GXD Expression  
Probe: MGI:4423298
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1756823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824342
Age: embryonic day 14.5
Image: euxassay_010961_18
Detected: true
Specimen Num: 15
GXD Expression  
Probe: MGI:4423298
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1756823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824342
Age: embryonic day 14.5
Image: euxassay_010961_17
Detected: true
Specimen Num: 14
GXD Expression  
Probe: MGI:4423298
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1756823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824342
Age: embryonic day 14.5
Image: euxassay_010961_16
Detected: true
Specimen Num: 13
GXD Expression  
Probe: MGI:4423298
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1756823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824342
Age: embryonic day 14.5
Image: euxassay_010961_15
Detected: true
Specimen Num: 12
GXD Expression  
Probe: MGI:4423298
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1756823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824342
Age: embryonic day 14.5
Image: euxassay_010961_14
Detected: true
Specimen Num: 11
GXD Expression  
Probe: MGI:4423298
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1756823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824342
Age: embryonic day 14.5
Image: euxassay_010961_13
Detected: true
Specimen Num: 10
GXD Expression  
Probe: MGI:4423298
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1756823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824342
Age: embryonic day 14.5
Image: euxassay_010961_12
Detected: true
Specimen Num: 9
GXD Expression  
Probe: MGI:4423298
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1756823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824342
Age: embryonic day 14.5
Image: euxassay_010961_11
Detected: true
Specimen Num: 8
GXD Expression  
Probe: MGI:4423298
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1756823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824342
Age: embryonic day 14.5
Image: euxassay_010961_10
Detected: true
Specimen Num: 7
GXD Expression  
Probe: MGI:4423298
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1756823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824342
Age: embryonic day 14.5
Image: euxassay_010961_09
Detected: true
Specimen Num: 6
GXD Expression  
Probe: MGI:4423298
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1756823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824342
Age: embryonic day 14.5
Image: euxassay_010961_08
Detected: true
Specimen Num: 5
GXD Expression  
Probe: MGI:4423298
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1756823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824342
Age: embryonic day 14.5
Image: euxassay_010961_07
Detected: true
Specimen Num: 4
GXD Expression  
Probe: MGI:4423298
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1756823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824342
Age: embryonic day 14.5
Image: euxassay_010961_06
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:4423298
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1756823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824342
Age: embryonic day 14.5
Image: euxassay_010961_05
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:4423298
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1756823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824342
Age: embryonic day 14.5
Image: euxassay_010961_04
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:4423298
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1755123
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824342
Age: embryonic day 14.5
Image: euxassay_010961_12
Detected: true
Specimen Num: 9
Publication
First Author: Horváth J
Year: 2005
Journal: Am J Respir Cell Mol Biol
Title: Identification and analysis of axonemal dynein light chain 1 in primary ciliary dyskinesia patients.
Volume: 33
Issue: 1
Pages: 41-7
Publication
First Author: Dong F
Year: 2014
Journal: J Cell Biol
Title: Pih1d3 is required for cytoplasmic preassembly of axonemal dynein in mouse sperm.
Volume: 204
Issue: 2
Pages: 203-13
Publication
First Author: Jung H
Year: 2018
Journal: Nat Neurosci
Title: Sexually dimorphic behavior, neuronal activity, and gene expression in Chd8-mutant mice.
Volume: 21
Issue: 9
Pages: 1218-1228
Publication      
First Author: The Jackson Laboratory Backcross DNA Panel Mapping Resource
Year: 1999
Journal: Database Release
Title: JAX BSS Panel Mapping Data
Publication      
First Author: MGI and IMPC
Year: 2017
Journal: MGI Direct Data Submission
Title: MGI Curation of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC)
Publication
First Author: Ko MS
Year: 2000
Journal: Development
Title: Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development.
Volume: 127
Issue: 8
Pages: 1737-49
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations for FANTOM2 data
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
Publication          
First Author: MGD Nomenclature Committee
Year: 1995
Publication
First Author: Gaudet P
Year: 2011
Journal: Brief Bioinform
Title: Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.
Volume: 12
Issue: 5
Pages: 449-62
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
Publication
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
Publication      
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations