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Search results 1 to 100 out of 111 for Dnase2a

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0.021s
Type Details Score
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Publication
First Author: Lan YY
Year: 2014
Journal: Cell Rep
Title: Dnase2a deficiency uncovers lysosomal clearance of damaged nuclear DNA via autophagy.
Volume: 9
Issue: 1
Pages: 180-92
Publication
First Author: Porcu S
Year: 2011
Journal: Mol Cell Biol
Title: Klf1 affects DNase II-alpha expression in the central macrophage of a fetal liver erythroblastic island: a non-cell-autonomous role in definitive erythropoiesis.
Volume: 31
Issue: 19
Pages: 4144-54
Publication
First Author: Oka T
Year: 2012
Journal: Nature
Title: Mitochondrial DNA that escapes from autophagy causes inflammation and heart failure.
Volume: 485
Issue: 7397
Pages: 251-5
Publication
First Author: Lan YY
Year: 2019
Journal: Aging Cell
Title: Extranuclear DNA accumulates in aged cells and contributes to senescence and inflammation.
Volume: 18
Issue: 2
Pages: e12901
Publication      
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
Publication
First Author: Baker KP
Year: 1998
Journal: Gene
Title: Molecular cloning and characterization of human and murine DNase II.
Volume: 215
Issue: 2
Pages: 281-9
Publication
First Author: Krieser RJ
Year: 2000
Journal: Gene
Title: Deoxyribonuclease II: structure and chromosomal localization of the murine gene, and comparison with the genomic structure of the human and three C. elegans homologs.
Volume: 252
Issue: 1-2
Pages: 155-62
Publication
First Author: Kawane K
Year: 2001
Journal: Science
Title: Requirement of DNase II for definitive erythropoiesis in the mouse fetal liver.
Volume: 292
Issue: 5521
Pages: 1546-9
Publication
First Author: Krieser RJ
Year: 2002
Journal: Cell Death Differ
Title: Deoxyribonuclease IIalpha is required during the phagocytic phase of apoptosis and its loss causes perinatal lethality.
Volume: 9
Issue: 9
Pages: 956-62
Publication  
First Author: Yamashita Y
Year: 2020
Journal: Mol Cell Biol
Title: Infertility Caused by Inefficient Apoptotic Germ Cell Clearance in Xkr8-Deficient Male Mice.
Volume: 40
Issue: 3
Publication
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
Publication        
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
Publication      
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
Publication      
First Author: University of California, Davis
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the University of California, Davis
Publication
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
Publication        
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
Publication
First Author: Ahn J
Year: 2018
Journal: Cancer Cell
Title: Extrinsic Phagocyte-Dependent STING Signaling Dictates the Immunogenicity of Dying Cells.
Volume: 33
Issue: 5
Pages: 862-873.e5
Publication
First Author: Gao D
Year: 2015
Journal: Proc Natl Acad Sci U S A
Title: Activation of cyclic GMP-AMP synthase by self-DNA causes autoimmune diseases.
Volume: 112
Issue: 42
Pages: E5699-705
Publication
First Author: Fischer H
Year: 2017
Journal: Sci Rep
Title: Inactivation of DNase1L2 and DNase2 in keratinocytes suppresses DNA degradation during epidermal cornification and results in constitutive parakeratosis.
Volume: 7
Issue: 1
Pages: 6433
Publication
First Author: Fischer H
Year: 2017
Journal: J Invest Dermatol
Title: Holocrine Secretion of Sebum Is a Unique DNase2-Dependent Mode of Programmed Cell Death.
Volume: 137
Issue: 3
Pages: 587-594
Publication  
First Author: Yoshikawa R
Year: 2019
Journal: J Virol
Title: Species-Specific Pathogenicity of Severe Fever with Thrombocytopenia Syndrome Virus Is Determined by Anti-STAT2 Activity of NSs.
Volume: 93
Issue: 10
Publication
First Author: Kawane K
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Cytokine-dependent but acquired immunity-independent arthritis caused by DNA escaped from degradation.
Volume: 107
Issue: 45
Pages: 19432-7
Publication
First Author: Baum R
Year: 2017
Journal: Arthritis Rheumatol
Title: STING Contributes to Abnormal Bone Formation Induced by Deficiency of DNase II in Mice.
Volume: 69
Issue: 2
Pages: 460-471
Publication  
First Author: Chan MP
Year: 2015
Journal: Nat Commun
Title: DNase II-dependent DNA digestion is required for DNA sensing by TLR9.
Volume: 6
Pages: 5853
Publication
First Author: Baum R
Year: 2015
Journal: J Immunol
Title: Cutting edge: AIM2 and endosomal TLRs differentially regulate arthritis and autoantibody production in DNase II-deficient mice.
Volume: 194
Issue: 3
Pages: 873-7
Publication
First Author: Ahn J
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: STING manifests self DNA-dependent inflammatory disease.
Volume: 109
Issue: 47
Pages: 19386-91
Publication
First Author: Okabe Y
Year: 2005
Journal: J Exp Med
Title: Toll-like receptor-independent gene induction program activated by mammalian DNA escaped from apoptotic DNA degradation.
Volume: 202
Issue: 10
Pages: 1333-9
Publication
First Author: Jakobs C
Year: 2015
Journal: PLoS One
Title: AIM2 Drives Joint Inflammation in a Self-DNA Triggered Model of Chronic Polyarthritis.
Volume: 10
Issue: 6
Pages: e0131702
Publication
First Author: Ohkouchi S
Year: 2013
Journal: PLoS One
Title: Biogenesis and proteolytic processing of lysosomal DNase II.
Volume: 8
Issue: 3
Pages: e59148
Publication
First Author: Kawane K
Year: 2003
Journal: Nat Immunol
Title: Impaired thymic development in mouse embryos deficient in apoptotic DNA degradation.
Volume: 4
Issue: 2
Pages: 138-44
Publication
First Author: Okabe Y
Year: 2008
Journal: Eur J Immunol
Title: IFN regulatory factor (IRF) 3/7-dependent and -independent gene induction by mammalian DNA that escapes degradation.
Volume: 38
Issue: 11
Pages: 3150-8
Publication
First Author: Nagasaka A
Year: 2010
Journal: Cell Death Differ
Title: Apaf-1-independent programmed cell death in mouse development.
Volume: 17
Issue: 6
Pages: 931-41
Publication
First Author: Kitahara Y
Year: 2010
Journal: Eur J Immunol
Title: Interferon-induced TRAIL-independent cell death in DNase II-/- embryos.
Volume: 40
Issue: 9
Pages: 2590-8
Publication
First Author: Yoshida H
Year: 2005
Journal: Nat Immunol
Title: Lethal anemia caused by interferon-beta produced in mouse embryos carrying undigested DNA.
Volume: 6
Issue: 1
Pages: 49-56
Publication
First Author: Hirata Y
Year: 2013
Journal: J Immunol
Title: TAK1-JNK axis mediates survival signal through Mcl1 stabilization in activated T cells.
Volume: 190
Issue: 9
Pages: 4621-6
Publication
First Author: Kawane K
Year: 2006
Journal: Nature
Title: Chronic polyarthritis caused by mammalian DNA that escapes from degradation in macrophages.
Volume: 443
Issue: 7114
Pages: 998-1002
Publication
First Author: MacLea KS
Year: 2003
Journal: Biochem J
Title: Structural requirements of human DNase II alpha for formation of the active enzyme: the role of the signal peptide, N-glycosylation, and disulphide bridging.
Volume: 371
Issue: Pt 3
Pages: 867-76
Publication
First Author: Howell DP
Year: 2003
Journal: Mol Ther
Title: Deoxyribonuclease II is a lysosomal barrier to transfection.
Volume: 8
Issue: 6
Pages: 957-63
Publication
First Author: Nagata M
Year: 2009
Journal: Genes Cells
Title: Transcription arrest relief by S-II/TFIIS during gene expression in erythroblast differentiation.
Volume: 14
Issue: 3
Pages: 371-80
Publication
First Author: Gaudet P
Year: 2011
Journal: Brief Bioinform
Title: Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.
Volume: 12
Issue: 5
Pages: 449-62
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2000
Title: Gene Ontology Annotation by electronic association of SwissProt Keywords with GO terms
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Rat to Mouse ISO GO annotation transfer
Publication
First Author: Sollars VE
Year: 2006
Journal: Mamm Genome
Title: Analysis of expansion of myeloid progenitors in mice to identify leukemic susceptibility genes.
Volume: 17
Issue: 8
Pages: 808-21
Publication
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
Publication
First Author: Nakayama E
Year: 2021
Journal: PLoS Pathog
Title: Neuroinvasiveness of the MR766 strain of Zika virus in IFNAR-/- mice maps to prM residues conserved amongst African genotype viruses.
Volume: 17
Issue: 7
Pages: e1009788
GXD Expression      
Probe: MGI:7526472
Assay Type: Northern blot
Annotation Date: 2023-09-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684622
Stage: TS22
Assay Id: MGI:7526478
Age: embryonic day 14.5
Specimen Label: +/+
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:7526472
Assay Type: Northern blot
Annotation Date: 2023-09-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684622
Stage: TS22
Assay Id: MGI:7526478
Age: embryonic day 14.5
Specimen Label: +/-
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:7526472
Assay Type: Northern blot
Annotation Date: 2023-09-15
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1684622
Stage: TS22
Assay Id: MGI:7526478
Age: embryonic day 14.5
Specimen Label: -/-
Detected: false
Specimen Num: 3
GXD Expression  
Probe: MGI:3232527
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1752923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824360
Age: embryonic day 14.5
Image: euxassay_008427_03
Specimen Label: euxassay_008427_03
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:3232527
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1752923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824360
Age: embryonic day 14.5
Image: euxassay_008427_04
Specimen Label: euxassay_008427_04
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:3232527
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1752923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824360
Age: embryonic day 14.5
Image: euxassay_008427_05
Specimen Label: euxassay_008427_05
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:3232527
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1752923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824360
Age: embryonic day 14.5
Image: euxassay_008427_06
Specimen Label: euxassay_008427_06
Detected: true
Specimen Num: 4
GXD Expression  
Probe: MGI:3232527
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1752923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824360
Age: embryonic day 14.5
Image: euxassay_008427_07
Specimen Label: euxassay_008427_07
Detected: true
Specimen Num: 5
GXD Expression  
Probe: MGI:3232527
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1752923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824360
Age: embryonic day 14.5
Image: euxassay_008427_08
Specimen Label: euxassay_008427_08
Detected: true
Specimen Num: 6
GXD Expression  
Probe: MGI:3232527
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1760623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824360
Age: embryonic day 14.5
Image: euxassay_008427_08
Specimen Label: euxassay_008427_08
Detected: true
Specimen Num: 6
GXD Expression  
Probe: MGI:3232527
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1752923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824360
Age: embryonic day 14.5
Image: euxassay_008427_09
Specimen Label: euxassay_008427_09
Detected: true
Specimen Num: 7
GXD Expression  
Probe: MGI:3232527
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1760623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824360
Age: embryonic day 14.5
Image: euxassay_008427_09
Specimen Label: euxassay_008427_09
Detected: true
Specimen Num: 7
GXD Expression  
Probe: MGI:3232527
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1760623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824360
Age: embryonic day 14.5
Image: euxassay_008427_10
Specimen Label: euxassay_008427_10
Detected: true
Specimen Num: 8
GXD Expression  
Probe: MGI:3232527
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1760623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824360
Age: embryonic day 14.5
Image: euxassay_008427_11
Specimen Label: euxassay_008427_11
Detected: true
Specimen Num: 9
GXD Expression  
Probe: MGI:3232527
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1752923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824360
Age: embryonic day 14.5
Image: euxassay_008427_12
Specimen Label: euxassay_008427_12
Detected: true
Specimen Num: 10
GXD Expression  
Probe: MGI:3232527
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1760623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824360
Age: embryonic day 14.5
Image: euxassay_008427_12
Specimen Label: euxassay_008427_12
Detected: true
Specimen Num: 10
GXD Expression  
Probe: MGI:3232527
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1760623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824360
Age: embryonic day 14.5
Image: euxassay_008427_13
Specimen Label: euxassay_008427_13
Detected: true
Specimen Num: 11
GXD Expression  
Probe: MGI:3232527
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1760623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824360
Age: embryonic day 14.5
Image: euxassay_008427_15
Specimen Label: euxassay_008427_15
Detected: true
Specimen Num: 12
GXD Expression  
Probe: MGI:3232527
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1760623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824360
Age: embryonic day 14.5
Image: euxassay_008427_16
Specimen Label: euxassay_008427_16
Detected: true
Specimen Num: 13
GXD Expression  
Probe: MGI:3232527
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1760623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824360
Age: embryonic day 14.5
Image: euxassay_008427_17
Specimen Label: euxassay_008427_17
Detected: true
Specimen Num: 14
GXD Expression  
Probe: MGI:3232527
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1760623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824360
Age: embryonic day 14.5
Image: euxassay_008427_18
Specimen Label: euxassay_008427_18
Detected: true
Specimen Num: 15
GXD Expression  
Probe: MGI:3232527
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1760623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824360
Age: embryonic day 14.5
Image: euxassay_008427_19
Specimen Label: euxassay_008427_19
Detected: true
Specimen Num: 16
GXD Expression  
Probe: MGI:3232527
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1752923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824360
Age: embryonic day 14.5
Image: euxassay_008427_20
Specimen Label: euxassay_008427_20
Detected: true
Specimen Num: 17
GXD Expression  
Probe: MGI:3232527
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1760623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824360
Age: embryonic day 14.5
Image: euxassay_008427_20
Specimen Label: euxassay_008427_20
Detected: true
Specimen Num: 17
GXD Expression  
Probe: MGI:3232527
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1752923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824360
Age: embryonic day 14.5
Image: euxassay_008427_21
Specimen Label: euxassay_008427_21
Detected: true
Specimen Num: 18
GXD Expression  
Probe: MGI:3232527
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1752923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824360
Age: embryonic day 14.5
Image: euxassay_008427_22
Specimen Label: euxassay_008427_22
Detected: true
Specimen Num: 19
GXD Expression  
Probe: MGI:3232527
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1752923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824360
Age: embryonic day 14.5
Image: euxassay_008427_23
Specimen Label: euxassay_008427_23
Detected: true
Specimen Num: 20
GXD Expression  
Probe: MGI:3232527
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1752923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824360
Age: embryonic day 14.5
Image: euxassay_008427_24
Specimen Label: euxassay_008427_24
Detected: true
Specimen Num: 21
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations