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Search results 1 to 100 out of 102 for Dnmbp

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0.037s
Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: zebrafish
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: chimpanzee
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Domain
Type: Family
Description: Dynamin-binding protein (DNMBP, also known as Tuba) is a scaffold protein that links dynamin with actin-regulating proteins. It binds a variety of actin regulatory proteins, including N-WASP, CR16, WAVE1, WIRE, PIR121, NAP1, and Ena/VASP proteins, via a C-terminal SH3 domain []. It plays a critical role in ciliogenesis and nephrogenesis, most likely via Cdc42 activation [].
Publication
First Author: Salazar MA
Year: 2003
Journal: J Biol Chem
Title: Tuba, a novel protein containing bin/amphiphysin/Rvs and Dbl homology domains, links dynamin to regulation of the actin cytoskeleton.
Volume: 278
Issue: 49
Pages: 49031-43
Gene
Type: gene
Organism: human
Publication
First Author: Baek JI
Year: 2016
Journal: J Biol Chem
Title: Dynamin Binding Protein (Tuba) Deficiency Inhibits Ciliogenesis and Nephrogenesis in Vitro and in Vivo.
Volume: 291
Issue: 16
Pages: 8632-43
Protein
Organism: Mus musculus/domesticus
Length: 1580  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 1576  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 1580  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 823  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 1264  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 188  
Fragment?: false
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Kovacs EM
Year: 2006
Journal: J Cell Sci
Title: Tuba stimulates intracellular N-WASP-dependent actin assembly.
Volume: 119
Issue: Pt 13
Pages: 2715-26
GXD Expression      
Probe: MGI:3028565
Assay Type: Northern blot
Annotation Date: 2004-02-23
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1689421
Stage: TS21
Assay Id: MGI:3028621
Age: embryonic day 13.0
Image: 2
Specimen Label: E13
Specimen Num: 1
GXD Expression      
Probe: MGI:3028565
Assay Type: Northern blot
Annotation Date: 2004-02-23
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1689425
Stage: TS25
Assay Id: MGI:3028621
Age: embryonic day 17.0
Image: 2
Specimen Label: E17
Specimen Num: 2
GXD Expression      
Probe: MGI:3028565
Assay Type: Northern blot
Annotation Date: 2004-02-23
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:3028621
Age: postnatal day 7
Image: 2
Specimen Label: P7
Specimen Num: 3
GXD Expression      
Probe: MGI:3028565
Assay Type: Northern blot
Annotation Date: 2004-02-23
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:3028621
Age: postnatal adult
Image: 2
Specimen Label: adult
Specimen Num: 4
GXD Expression    
Probe: MGI:3028565
Assay Type: Northern blot
Annotation Date: 2004-02-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:3028621
Age: postnatal adult
Image: 2
Specimen Label: L
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:3028565
Assay Type: Northern blot
Annotation Date: 2004-02-23
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:3028621
Age: postnatal adult
Image: 2
Specimen Label: T
Specimen Num: 6
GXD Expression      
Probe: MGI:3759589
Assay Type: RT-PCR
Annotation Date: 2007-10-30
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:3759646
Age: postnatal adult
Specimen Label: Brain
Detected: false
Specimen Num: 2
GXD Expression      
Probe: MGI:3759589
Assay Type: RT-PCR
Annotation Date: 2007-10-30
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1619828
Stage: TS28
Assay Id: MGI:3759646
Age: postnatal adult
Specimen Label: Eye
Detected: false
Specimen Num: 3
GXD Expression      
Probe: MGI:3759589
Assay Type: RT-PCR
Annotation Date: 2007-10-30
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:3759646
Age: postnatal adult
Specimen Label: Heart
Detected: false
Specimen Num: 4
GXD Expression      
Probe: MGI:3759589
Assay Type: RT-PCR
Annotation Date: 2007-10-30
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1603922
Stage: TS22
Assay Id: MGI:3759646
Age: embryonic day 14.5
Specimen Label: E14.5
Detected: false
Specimen Num: 5
GXD Expression    
Probe: MGI:7447145
Assay Type: RT-PCR
Annotation Date: 2023-03-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1783824
Stage: TS24
Assay Id: MGI:7447166
Age: embryonic day 16.5
Image: S11
Specimen Label: E16.5
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:7447145
Assay Type: RT-PCR
Annotation Date: 2023-03-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1783827
Stage: TS27
Assay Id: MGI:7447166
Age: postnatal day 3
Image: S11
Specimen Label: P3
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:4427604
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1783823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824364
Age: embryonic day 14.5
Image: euxassay_016234_23
Specimen Label: euxassay_016234_23
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:4427604
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1783823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824364
Age: embryonic day 14.5
Image: euxassay_016234_24
Specimen Label: euxassay_016234_24
Detected: true
Specimen Num: 2
Publication
First Author: Polle L
Year: 2014
Journal: Structure
Title: Structural details of human tuba recruitment by InlC of Listeria monocytogenes elucidate bacterial cell-cell spreading.
Volume: 22
Issue: 2
Pages: 304-14
Publication  
First Author: Nedelko T
Year: 2012
Journal: BMC Genomics
Title: Distinct gene loci control the host response to influenza H1N1 virus infection in a time-dependent manner.
Volume: 13
Pages: 411
Publication  
First Author: Sheehan CJ
Year: 2020
Journal: Development
Title: Dosage-dependent requirements of Magoh for cortical interneuron generation and survival.
Volume: 147
Issue: 1
Publication
First Author: Yoshizawa M
Year: 2003
Journal: Gene Expr Patterns
Title: Dynamic and coordinated expression profile of dbl-family guanine nucleotide exchange factors in the developing mouse brain.
Volume: 3
Issue: 3
Pages: 375-81
Publication
First Author: Choquet H
Year: 2021
Journal: Nat Commun
Title: A large multiethnic GWAS meta-analysis of cataract identifies new risk loci and sex-specific effects.
Volume: 12
Issue: 1
Pages: 3595
Publication
First Author: Roma G
Year: 2007
Journal: Genome Res
Title: A novel view of the transcriptome revealed from gene trapping in mouse embryonic stem cells.
Volume: 17
Issue: 7
Pages: 1051-60
Publication    
First Author: Yoo D
Year: 2022
Journal: Elife
Title: Little skate genome provides insights into genetic programs essential for limb-based locomotion.
Volume: 11
Publication      
First Author: MGI and IMPC
Year: 2017
Journal: MGI Direct Data Submission
Title: MGI Curation of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC)
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: FANTOM2 Data Curation in Mouse Genome Informatics
Publication      
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
Publication
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
Publication      
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
Publication        
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Rat to Mouse ISO GO annotation transfer
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
Publication
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
Publication      
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
Publication
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
Publication        
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
Publication        
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
Publication
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
Publication
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication        
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
DO Term
Publication
First Author: Kuwano R
Year: 2006
Journal: Hum Mol Genet
Title: Dynamin-binding protein gene on chromosome 10q is associated with late-onset Alzheimer's disease.
Volume: 15
Issue: 13
Pages: 2170-82
Publication  
First Author: Cestra G
Year: 2005
Journal: Methods Enzymol
Title: Tuba, a GEF for CDC42, links dynamin to actin regulatory proteins.
Volume: 404
Pages: 537-45
Protein Domain
Type: Domain
Description: Dynamin-binding protein (DNMBP,also known as Tuba) is a scaffold protein that links dynamin with actin-regulating proteins. It binds a variety of actin regulatory proteins, including N-WASP, CR16, WAVE1, WIRE, PIR121, NAP1, and Ena/VASP proteins, via a C-terminal SH3 domain []. It plays a critical role in ciliogenesis and nephrogenesis, most likely via Cdc42 activation [].The four N-terminal SH3 domains of DNMBP binds the GTPase dynamin, which plays an important role in the fission of endocytic vesicles []. This entry represents the first N-terminal SH3 domain.
Protein Domain
Type: Domain
Description: Dynamin-binding protein (DNMBP, also known as Tuba) is a scaffold protein that links dynamin with actin-regulating proteins. It binds a variety of actin regulatory proteins, including N-WASP, CR16, WAVE1, WIRE, PIR121, NAP1, and Ena/VASP proteins, via a C-terminal SH3 domain []. It plays a critical role in ciliogenesis and nephrogenesis, most likely via Cdc42 activation [].The four N-terminal SH3 domains of DNMBP binds the GTPase dynamin, which plays an important role in the fission of endocytic vesicles []. This entry represents the second N-terminal SH3 domain.
Protein Domain
Type: Domain
Description: Dynamin-binding protein (DNMBP, also known as Tuba) is a scaffold protein that links dynamin with actin-regulating proteins. It binds a variety of actin regulatory proteins, including N-WASP, CR16, WAVE1, WIRE, PIR121, NAP1, and Ena/VASP proteins, via a C-terminal SH3 domain []. It plays a critical role in ciliogenesis and nephrogenesis, most likely via Cdc42 activation [].The four N-terminal SH3 domains of DNMBP binds the GTPase dynamin, which plays an important role in the fission of endocytic vesicles []. This entry represents the third N-terminal SH3 domain.
Protein Domain
Type: Domain
Description: Dynamin-binding protein (DNMBP, also known as Tuba) is a scaffold protein that links dynamin with actin-regulating proteins. It binds a variety of actin regulatory proteins, including N-WASP, CR16, WAVE1, WIRE, PIR121, NAP1, and Ena/VASP proteins, via a C-terminal SH3 domain []. It plays a critical role in ciliogenesis and nephrogenesis, most likely via Cdc42 activation [].The C-terminal SH3 domains of DNMBP bind to N-WASP and Ena/VASP proteins, which are key regulatory proteins of the actin cytoskeleton []. This entry represents the first C-terminal SH3 domain.
Protein Domain
Type: Domain
Description: ARHGEF37 contains a RhoGEF (or Dbl homology, DH) domain followed by a Bin/Amphiphysin/Rvs (BAR) domain, and two C-terminal SH3 domains. Its specific function is unknown. Its domain architecture is similar to the C-terminal half of DNMBP or Tuba, a cdc42-specific GEF that provides a functional link between dynamin, Rho GTPase signaling, and actin dynamics, and plays an important role in regulating cell junction configuration. GEFsactivate small GTPases by exchanging bound GDP for free GTP [].This entry represents the firs C-terminal SH3 domain of ARHGEF37.