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Search results 1 to 100 out of 125 for Doc2b

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Hits by Strain

Hits by Category

Type Details Score
Gene
8447 | DOC2B
Type: gene
Organism: human
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Gene
611233 | DOC2B
Type: gene
Organism: dog, domestic
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Gene
785428 | DOC2B
Type: gene
Organism: cattle
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Gene
417624 | DOC2B
Type: gene
Organism: chicken
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Gene
100006713 | doc2b
Type: gene
Organism: zebrafish
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Gene
699082 | DOC2B
Type: gene
Organism: macaque, rhesus
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Gene
100496262 | doc2b
Type: gene
Organism: frog, western clawed
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Gene
81820 | Doc2b
Type: gene
Organism: rat
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Gene
454397 | DOC2B
Type: gene
Organism: chimpanzee
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Protein Coding Gene
MGI:1100497 | Doc2b
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
22698913 | J:208531
First Author: Ramalingam L
Year: 2012
Journal: Diabetes
Title: Doc2b is a key effector of insulin secretion and skeletal muscle insulin sensitivity.
Volume: 61
Issue: 10
Pages: 2424-32
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Publication
20150444 | J:158605
First Author: Groffen AJ
Year: 2010
Journal: Science
Title: Doc2b is a high-affinity Ca2+ sensor for spontaneous neurotransmitter release.
Volume: 327
Issue: 5973
Pages: 1614-8
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Publication
29661782 | J:264812
First Author: Aslamy A
Year: 2018
Journal: Diabetes
Title: Doc2b Protects β-Cells Against Inflammatory Damage and Enhances Function.
Volume: 67
Issue: 7
Pages: 1332-1344
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Publication
23537531 | J:224805
First Author: Lavi A
Year: 2014
Journal: Cereb Cortex
Title: DOC2B and Munc13-1 differentially regulate neuronal network activity.
Volume: 24
Issue: 9
Pages: 2309-23
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Publication
18596155 | J:137824
First Author: Friedrich R
Year: 2008
Journal: J Neurosci
Title: DOC2B acts as a calcium switch and enhances vesicle fusion.
Volume: 28
Issue: 27
Pages: 6794-806
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Publication
16515538 | J:108537
First Author: Groffen AJ
Year: 2006
Journal: J Neurochem
Title: DOC2A and DOC2B are sensors for neuronal activity with unique calcium-dependent and kinetic properties.
Volume: 97
Issue: 3
Pages: 818-33
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Publication
24705606 | J:213752
First Author: Ramalingam L
Year: 2014
Journal: Diabetologia
Title: Doc2b enrichment enhances glucose homeostasis in mice via potentiation of insulin secretion and peripheral insulin sensitivity.
Volume: 57
Issue: 7
Pages: 1476-84
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Publication
32347796 | J:291939
   
First Author: Khan MM
Year: 2020
Journal: Elife
Title: Loss of Doc2b does not influence transmission at Purkinje cell to deep nuclei synapses under physiological conditions.
Volume: 9
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Publication
24133251 | J:202747
First Author: Pinheiro PS
Year: 2013
Journal: J Neurosci
Title: Doc2b synchronizes secretion from chromaffin cells by stimulating fast and inhibiting sustained release.
Volume: 33
Issue: 42
Pages: 16459-70
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Publication
29274147 | J:254968
   
First Author: Houy S
Year: 2017
Journal: Elife
Title: Doc2B acts as a calcium sensor for vesicle priming requiring synaptotagmin-1, Munc13-2 and SNAREs.
Volume: 6
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Publication
25190515 | J:217823
First Author: Ramalingam L
Year: 2014
Journal: Biochem J
Title: Doc2b serves as a scaffolding platform for concurrent binding of multiple Munc18 isoforms in pancreatic islet β-cells.
Volume: 464
Issue: 2
Pages: 251-8
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Publication
31594980 | J:297992
First Author: Bourgeois-Jaarsma Q
Year: 2019
Journal: Sci Rep
Title: Doc2b Ca2+ binding site mutants enhance synaptic release at rest at the expense of sustained synaptic strength.
Volume: 9
Issue: 1
Pages: 14408
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Publication
30707251 | J:279061
First Author: Zhang J
Year: 2019
Journal: Diabetologia
Title: DOC2B promotes insulin sensitivity in mice via a novel KLC1-dependent mechanism in skeletal muscle.
Volume: 62
Issue: 5
Pages: 845-859
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GXD Expression
GXD Expression
   
Probe: MGI:6171390
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689419
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:6190139
Age: embryonic day 11.5
Specimen Label: Table S2 - E11.5 - Doc2b
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:6171390
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689421
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:6190139
Age: embryonic day 13.5
Specimen Label: Table S2 - E13.5 - Doc2b
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:6171390
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689424
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:6190139
Age: embryonic day 15.5
Specimen Label: Table S2 - E15.5 - Doc2b
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:6171390
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689426
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:6190139
Age: embryonic day 18.5
Specimen Label: Table S2 - E18.5 - Doc2b
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:6171390
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6190139
Age: postnatal day 4
Specimen Label: Table S2 - P4 - Doc2b
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
   
Probe: MGI:6171390
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6190139
Age: postnatal day 14
Specimen Label: Table S2 - P14 - Doc2b
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
   
Probe: MGI:6171390
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6190139
Age: postnatal day 28
Specimen Label: Table S2 - P28 - Doc2b
Detected: true
Specimen Num: 7
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Publication
25005332 | J:218125
First Author: Li J
Year: 2014
Journal: Diabetologia
Title: DOC2 isoforms play dual roles in insulin secretion and insulin-stimulated glucose uptake.
Volume: 57
Issue: 10
Pages: 2173-82
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Publication
19033398 | J:146942
First Author: Fukuda N
Year: 2009
Journal: Diabetes
Title: DOC2B: a novel syntaxin-4 binding protein mediating insulin-regulated GLUT4 vesicle fusion in adipocytes.
Volume: 58
Issue: 2
Pages: 377-84
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Publication
8902635 | J:39762
First Author: Kojima T
Year: 1996
Journal: J Biochem
Title: Calcium-dependent phospholipid binding to the C2A domain of a ubiquitous form of double C2 protein (Doc2 beta).
Volume: 120
Issue: 3
Pages: 671-6
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Publication
21521611 | J:174823
First Author: Pang ZP
Year: 2011
Journal: Neuron
Title: Doc2 supports spontaneous synaptic transmission by a Ca(2+)-independent mechanism.
Volume: 70
Issue: 2
Pages: 244-51
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Publication
32098902 | J:286584
First Author: Díez-Arazola R
Year: 2020
Journal: J Neurosci
Title: Doc2 Proteins Are Not Required for the Increased Spontaneous Release Rate in Synaptotagmin-1-Deficient Neurons.
Volume: 40
Issue: 13
Pages: 2606-2617
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Publication
33589589 | J:304624
First Author: Wu H
Year: 2021
Journal: Nat Commun
Title: Distinct subtypes of proprioceptive dorsal root ganglion neurons regulate adaptive proprioception in mice.
Volume: 12
Issue: 1
Pages: 1026
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Protein Coding Gene
MGP_CAROLIEiJ_G0016749 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0018723 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0018689 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0018659 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0018663 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0018476 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_1100497 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0019114 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0018030 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0018446 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0018555 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0018545 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0018626 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0018571 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0019154 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0017801 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0018083 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0017886 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0017592 | -
Type: protein_coding_gene
Organism: Mus spretus
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GXD Expression
GXD Expression
     
Probe: MGI:3576309
Assay Type: Western blot
Annotation Date: 2005-05-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754426
Stage: TS26
Assay Id: MGI:3576322
Age: embryonic day 18.5
Specimen Label: +/+
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:3576309
Assay Type: Western blot
Annotation Date: 2005-05-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754426
Stage: TS26
Assay Id: MGI:3576322
Age: embryonic day 18.5
Specimen Label: -/-
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:6444283
Assay Type: RT-PCR
Annotation Date: 2020-07-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1716828
Stage: TS28
Assay Id: MGI:6444881
Age: postnatal week 5
Specimen Label: wild type control
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:6444283
Assay Type: RT-PCR
Annotation Date: 2020-07-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1716828
Stage: TS28
Assay Id: MGI:6444881
Age: postnatal week 5
Specimen Label: miR-183C
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:4423354
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1843823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824368
Age: embryonic day 14.5
Image: euxassay_008012_07
Specimen Label: euxassay_008012_07
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:4423354
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1843823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824368
Age: embryonic day 14.5
Image: euxassay_008012_08
Specimen Label: euxassay_008012_08
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:4423354
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1843823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824368
Age: embryonic day 14.5
Image: euxassay_008012_15
Specimen Label: euxassay_008012_15
Detected: true
Specimen Num: 8
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GXD Expression
GXD Expression
 
Probe: MGI:4423354
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1822623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824368
Age: embryonic day 14.5
Image: euxassay_008012_07
Specimen Label: euxassay_008012_07
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:4423354
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1822623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824368
Age: embryonic day 14.5
Image: euxassay_008012_08
Specimen Label: euxassay_008012_08
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:4423354
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1822623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824368
Age: embryonic day 14.5
Image: euxassay_008012_13
Specimen Label: euxassay_008012_13
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
 
Probe: MGI:4423354
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1679723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824368
Age: embryonic day 14.5
Image: euxassay_008012_09
Specimen Label: euxassay_008012_09
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
 
Probe: MGI:4423354
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1679723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824368
Age: embryonic day 14.5
Image: euxassay_008012_10
Specimen Label: euxassay_008012_10
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
 
Probe: MGI:4423354
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1679723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824368
Age: embryonic day 14.5
Image: euxassay_008012_16
Specimen Label: euxassay_008012_16
Detected: true
Specimen Num: 9
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GXD Expression
GXD Expression
 
Probe: MGI:4423354
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1679723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824368
Age: embryonic day 14.5
Image: euxassay_008012_17
Specimen Label: euxassay_008012_17
Detected: true
Specimen Num: 10
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GXD Expression
GXD Expression
 
Probe: MGI:4423354
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1715823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824368
Age: embryonic day 14.5
Image: euxassay_008012_10
Specimen Label: euxassay_008012_10
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
 
Probe: MGI:4423354
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1715823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824368
Age: embryonic day 14.5
Image: euxassay_008012_11
Specimen Label: euxassay_008012_11
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
 
Probe: MGI:4423354
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1715823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824368
Age: embryonic day 14.5
Image: euxassay_008012_12
Specimen Label: euxassay_008012_12
Detected: true
Specimen Num: 6
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Publication
26195798 | J:226054
First Author: Xue R
Year: 2015
Journal: Proc Natl Acad Sci U S A
Title: Structural elements that underlie Doc2β function during asynchronous synaptic transmission.
Volume: 112
Issue: 31
Pages: E4316-25
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Publication
17548353 | J:161112
First Author: Ke B
Year: 2007
Journal: J Biol Chem
Title: Doc2beta is a novel Munc18c-interacting partner and positive effector of syntaxin 4-mediated exocytosis.
Volume: 282
Issue: 30
Pages: 21786-97
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Publication
29754754 | J:267944
First Author: Courtney NA
Year: 2018
Journal: Neuron
Title: Excitatory and Inhibitory Neurons Utilize Different Ca2+ Sensors and Sources to Regulate Spontaneous Release.
Volume: 98
Issue: 5
Pages: 977-991.e5
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Publication
33753311 | J:317639
 
First Author: Bourgeois-Jaarsma Q
Year: 2021
Journal: Mol Cell Neurosci
Title: Ca2+ sensor proteins in spontaneous release and synaptic plasticity: Limited contribution of Doc2c, rabphilin-3a and synaptotagmin 7 in hippocampal glutamatergic neurons.
Volume: 112
Pages: 103613
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Publication
27091977 | J:232211
First Author: de Jong AP
Year: 2016
Journal: Proc Natl Acad Sci U S A
Title: Phosphorylation of synaptotagmin-1 controls a post-priming step in PKC-dependent presynaptic plasticity.
Volume: 113
Issue: 18
Pages: 5095-100
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Publication
31260032 | J:277122
First Author: Buenaventura DF
Year: 2019
Journal: Invest Ophthalmol Vis Sci
Title: Identification of Genes With Enriched Expression in Early Developing Mouse Cone Photoreceptors.
Volume: 60
Issue: 8
Pages: 2787-2799
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Publication
15145078 | J:91381
First Author: Bouwman J
Year: 2004
Journal: Neuroscience
Title: Quantification of synapse formation and maintenance in vivo in the absence of synaptic release.
Volume: 126
Issue: 1
Pages: 115-26
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Publication
15935055 | J:99424
First Author: Toonen RF
Year: 2005
Journal: J Neurochem
Title: Munc18-1 stabilizes syntaxin 1, but is not essential for syntaxin 1 targeting and SNARE complex formation.
Volume: 93
Issue: 6
Pages: 1393-400
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Publication
16284245 | J:103829
First Author: Chen B
Year: 2005
Journal: Proc Natl Acad Sci U S A
Title: Fezl regulates the differentiation and axon targeting of layer 5 subcortical projection neurons in cerebral cortex.
Volume: 102
Issue: 47
Pages: 17184-9
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Publication
23341629 | J:193822
First Author: Lumayag S
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Inactivation of the microRNA-183/96/182 cluster results in syndromic retinal degeneration.
Volume: 110
Issue: 6
Pages: E507-16
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Publication
24952961 | J:215487
First Author: Thompson CL
Year: 2014
Journal: Neuron
Title: A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain.
Volume: 83
Issue: 2
Pages: 309-323
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Publication
- | J:155845
     
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
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Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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