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Search results 1 to 100 out of 149 for Dock9

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Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: chimpanzee
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: dog, domestic
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Domain
Type: Family
Description: DOCK family members are evolutionarily conserved guanine nucleotide exchange factors (GEFs) for Rho-family GTPases []. DOCK proteins are required during several cellular processes, such as cell motility and phagocytosis. The N-terminal SH3 domain of the DOCK proteins functions as an inhibitor of GEF, which can be relieved upon its binding to the ELMO1-3 adaptor proteins, after their binding to active RhoG at the plasma membrane [, ]. DOCK family proteins are categorised into four subfamilies based on their sequence homology: DOCK-A subfamily (DOCK1/180, 2, 5), DOCK-B subfamily (DOCK3, 4), DOCK-C subfamily (DOCK6, 7, 8), DOCK-D subfamily (DOCK9, 10, 11) []. This entry represents DOCK9 (also known as Zizimin). DOCK9 and DOCK11 activate Cdc42 [, ].
Publication
First Author: Nishikimi A
Year: 2005
Journal: FEBS Lett
Title: Zizimin2: a novel, DOCK180-related Cdc42 guanine nucleotide exchange factor expressed predominantly in lymphocytes.
Volume: 579
Issue: 5
Pages: 1039-46
Gene
Type: gene
Organism: human
Protein
Organism: Mus musculus/domesticus
Length: 738  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 2058  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 1920  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 2088  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 2042  
Fragment?: false
Gene
Type: gene
Organism: human
Protein
Organism: Mus musculus/domesticus
Length: 133  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 166  
Fragment?: true
Publication
First Author: Meller N
Year: 2002
Journal: Nat Cell Biol
Title: Zizimin1, a novel Cdc42 activator, reveals a new GEF domain for Rho proteins.
Volume: 4
Issue: 9
Pages: 639-47
Protein
Organism: Mus musculus/domesticus
Length: 279  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 2055  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 2113  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 2088  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 2042  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 2058  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 2055  
Fragment?: false
Publication
First Author: Lu M
Year: 2005
Journal: Curr Biol
Title: A Steric-inhibition model for regulation of nucleotide exchange via the Dock180 family of GEFs.
Volume: 15
Issue: 4
Pages: 371-7
Publication
First Author: Gadea G
Year: 2014
Journal: Eur J Cell Biol
Title: Dock-family exchange factors in cell migration and disease.
Volume: 93
Issue: 10-12
Pages: 466-77
Publication
First Author: Côté JF
Year: 2002
Journal: J Cell Sci
Title: Identification of an evolutionarily conserved superfamily of DOCK180-related proteins with guanine nucleotide exchange activity.
Volume: 115
Issue: Pt 24
Pages: 4901-13
Publication
First Author: Namekata K
Year: 2020
Journal: J Biol Chem
Title: Roles of the DOCK-D family proteins in a mouse model of neuroinflammation.
Volume: 295
Issue: 19
Pages: 6710-6720
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
GXD Expression      
Probe: MGI:1332096
Assay Type: RT-PCR
Annotation Date: 1999-03-18
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1603911
Stage: TS11
Assay Id: MGI:1332097
Age: embryonic day 7.5
Specimen Label: 1x
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:1332096
Assay Type: RT-PCR
Annotation Date: 1999-03-18
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1603911
Stage: TS11
Assay Id: MGI:1332097
Age: embryonic day 7.5
Specimen Label: 10x
Detected: false
Specimen Num: 2
GXD Expression      
Probe: MGI:1332096
Assay Type: RT-PCR
Annotation Date: 1999-03-18
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1603911
Stage: TS11
Assay Id: MGI:1332097
Age: embryonic day 7.5
Specimen Label: 100x
Detected: false
Specimen Num: 3
GXD Expression      
Probe: MGI:1332096
Assay Type: RT-PCR
Annotation Date: 1999-03-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1604211
Stage: TS11
Assay Id: MGI:1332097
Age: embryonic day 7.5
Specimen Label: 1x
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:1332096
Assay Type: RT-PCR
Annotation Date: 1999-03-18
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1604211
Stage: TS11
Assay Id: MGI:1332097
Age: embryonic day 7.5
Specimen Label: 10x
Detected: false
Specimen Num: 5
GXD Expression      
Probe: MGI:1332096
Assay Type: RT-PCR
Annotation Date: 1999-03-18
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1604211
Stage: TS11
Assay Id: MGI:1332097
Age: embryonic day 7.5
Specimen Label: 100x
Detected: false
Specimen Num: 6
GXD Expression    
Probe: MGI:7542946
Assay Type: RT-PCR
Annotation Date: 2023-10-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3284226
Stage: TS26
Assay Id: MGI:7543209
Age: embryonic day 19.0
Image: S4
Specimen Label: WT
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:7542946
Assay Type: RT-PCR
Annotation Date: 2023-10-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3284226
Stage: TS26
Assay Id: MGI:7543209
Age: embryonic day 19.0
Image: S4
Specimen Label: dMut
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:7542947
Assay Type: RT-PCR
Annotation Date: 2023-10-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3284226
Stage: TS26
Assay Id: MGI:7543210
Age: embryonic day 19.0
Image: S4
Specimen Label: WT
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:7542947
Assay Type: RT-PCR
Annotation Date: 2023-10-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3284226
Stage: TS26
Assay Id: MGI:7543210
Age: embryonic day 19.0
Image: S4
Specimen Label: dMut
Detected: true
Specimen Num: 2
GXD Expression
Probe: MGI:6358424
Assay Type: RNA in situ
Annotation Date: 2019-09-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1640618
Pattern: Regionally restricted
Stage: TS18
Assay Id: MGI:6358586
Age: embryonic day 11.0
Image: S8K
Note: Expression was detected in the dorsal and ventral muscle masses.
Specimen Label: S8K
Detected: true
Specimen Num: 1
GXD Expression
Probe: MGI:6358424
Assay Type: RNA in situ
Annotation Date: 2019-09-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1640618
Pattern: Regionally restricted
Stage: TS18
Assay Id: MGI:6358586
Age: embryonic day 11.0
Image: S8M
Note: Expression was detected in the dorsal and ventral muscle masses.
Specimen Label: S8M
Detected: true
Specimen Num: 3
GXD Expression
Probe: MGI:6358424
Assay Type: RNA in situ
Annotation Date: 2019-09-06
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1640618
Pattern: Regionally restricted
Stage: TS18
Assay Id: MGI:6358586
Age: embryonic day 11.0
Image: S8N
Note: Expression was downregulated in the dorsal and ventral muscle masses in the conditional knockout mutant.
Specimen Label: S8N
Detected: true
Specimen Num: 4
GXD Expression
Probe: MGI:6358424
Assay Type: RNA in situ
Annotation Date: 2019-09-06
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1640618
Pattern: Regionally restricted
Stage: TS18
Assay Id: MGI:6358586
Age: embryonic day 11.0
Image: S8L
Note: Expression was downregulated in the dorsal and ventral muscle masses in the conditional knockout mutant.
Specimen Label: S8L
Detected: true
Specimen Num: 2
GXD Expression
Probe: MGI:6358424
Assay Type: RNA in situ
Annotation Date: 2019-09-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1640818
Pattern: Regionally restricted
Stage: TS18
Assay Id: MGI:6358586
Age: embryonic day 11.0
Image: S8K
Note: Expression was detected in condensing mesenchyme.
Specimen Label: S8K
Detected: true
Specimen Num: 1
GXD Expression
Probe: MGI:6358424
Assay Type: RNA in situ
Annotation Date: 2019-09-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1640818
Pattern: Regionally restricted
Stage: TS18
Assay Id: MGI:6358586
Age: embryonic day 11.0
Image: S8L
Note: Expression was unaffected in condensing mesenchyme in the conditional knockout mutant.
Specimen Label: S8L
Detected: true
Specimen Num: 2
GXD Expression
Probe: MGI:6358424
Assay Type: RNA in situ
Annotation Date: 2019-09-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1640818
Pattern: Regionally restricted
Stage: TS18
Assay Id: MGI:6358586
Age: embryonic day 11.0
Image: S8M
Note: Expression was detected in condensing mesenchyme.
Specimen Label: S8M
Detected: true
Specimen Num: 3
GXD Expression
Probe: MGI:6358424
Assay Type: RNA in situ
Annotation Date: 2019-09-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1640818
Pattern: Regionally restricted
Stage: TS18
Assay Id: MGI:6358586
Age: embryonic day 11.0
Image: S8N
Note: Expression was unaffected in condensing mesenchyme in the conditional knockout mutant.
Specimen Label: S8N
Detected: true
Specimen Num: 4
Publication
First Author: Jaudon F
Year: 2015
Journal: Mol Biol Cell
Title: The RhoGEF DOCK10 is essential for dendritic spine morphogenesis.
Volume: 26
Issue: 11
Pages: 2112-27
Publication
First Author: Hu JK
Year: 2012
Journal: Genes Dev
Title: Autonomous and nonautonomous roles of Hedgehog signaling in regulating limb muscle formation.
Volume: 26
Issue: 18
Pages: 2088-102
Publication
First Author: Nakano Y
Year: 2019
Journal: Cell Rep
Title: Overlapping Activities of Two Neuronal Splicing Factors Switch the GABA Effect from Excitatory to Inhibitory by Regulating REST.
Volume: 27
Issue: 3
Pages: 860-871.e8
Publication
First Author: Ko MS
Year: 1998
Journal: Hum Mol Genet
Title: Genome-wide mapping of unselected transcripts from extraembryonic tissue of 7.5-day mouse embryos reveals enrichment in the t-complex and under-representation on the X chromosome.
Volume: 7
Issue: 12
Pages: 1967-78
Publication      
First Author: The Jackson Laboratory DNA Panel Mapping Resource
Year: 1999
Journal: Database Release
Title: JAX Interspecific Backcross BSS and BSB Public Mapping Data
Publication
First Author: Okazaki N
Year: 2003
Journal: DNA Res
Title: Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.
Volume: 10
Issue: 1
Pages: 35-48
Publication
First Author: Cobellis G
Year: 2005
Journal: Nucleic Acids Res
Title: Tagging genes with cassette-exchange sites.
Volume: 33
Issue: 4
Pages: e44
Publication
First Author: Ko MS
Year: 2000
Journal: Development
Title: Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development.
Volume: 127
Issue: 8
Pages: 1737-49
Publication      
First Author: The Jackson Laboratory
Year: 2012
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by The Jackson Laboratory
Publication
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
Publication      
First Author: Lennon G
Year: 1999
Journal: Database Download
Title: WashU-HHMI Mouse EST Project
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
Publication      
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
Publication        
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
Publication        
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
Publication      
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
Publication
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
Publication        
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2000
Title: Gene Ontology Annotation by electronic association of SwissProt Keywords with GO terms
Publication      
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
Publication
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication      
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication        
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project