|  Help  |  About  |  Contact Us

Search our database by keyword

Examples

  • Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
  • Use OR to search for either of two terms (e.g. OR mus) or quotation marks to search for phrases (e.g. "dna binding").
  • Boolean search syntax is supported: e.g. Balb* for partial matches or mus AND NOT embryo to exclude a term

Search results 1 to 100 out of 899 for E2f1

<< First    < Previous  |  Next >    Last >>
0.046s

Categories

Hits by Pathway

Hits by Strain

Hits by Category

Type Details Score
Gene
Type: gene
Organism: Homo sapiens
Gene
Type: gene
Organism: Danio rerio
Gene
Type: gene
Organism: Drosophila melanogaster
Gene
Type: gene
Organism: Rattus norvegicus
Protein
Organism: Mus musculus
Length: 430  
Fragment?: false
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Gene
Type: gene
Organism: Homo sapiens
Publication
First Author: Grouwels G
Year: 2010
Journal: Diabetes
Title: Ectopic expression of E2F1 stimulates beta-cell proliferation and function.
Volume: 59
Issue: 6
Pages: 1435-44
Publication
First Author: Russell JL
Year: 2002
Journal: Mol Cell Biol
Title: ARF differentially modulates apoptosis induced by E2F1 and Myc.
Volume: 22
Issue: 5
Pages: 1360-8
Publication
First Author: Ladu S
Year: 2008
Journal: Gastroenterology
Title: E2F1 inhibits c-Myc-driven apoptosis via PIK3CA/Akt/mTOR and COX-2 in a mouse model of human liver cancer.
Volume: 135
Issue: 4
Pages: 1322-32
Publication
First Author: Lazzerini Denchi E
Year: 2005
Journal: EMBO Rep
Title: E2F1 is crucial for E2F-dependent apoptosis.
Volume: 6
Issue: 7
Pages: 661-8
Publication
First Author: Li Y
Year: 1994
Journal: Mol Cell Biol
Title: Cloning, chromosomal location, and characterization of mouse E2F1.
Volume: 14
Issue: 3
Pages: 1861-9
Publication
First Author: Pierce AM
Year: 1999
Journal: Mol Cell Biol
Title: E2F1 has both oncogenic and tumor-suppressive properties in a transgenic model.
Volume: 19
Issue: 9
Pages: 6408-14
Publication
First Author: Russell JL
Year: 2006
Journal: Oncogene
Title: E2F1 suppresses skin carcinogenesis via the ARF-p53 pathway.
Volume: 25
Issue: 6
Pages: 867-76
Publication
First Author: Raimundo N
Year: 2012
Journal: Cell
Title: Mitochondrial stress engages E2F1 apoptotic signaling to cause deafness.
Volume: 148
Issue: 4
Pages: 716-26
Publication
First Author: Wang D
Year: 2000
Journal: Mol Cell Biol
Title: E2F4 and E2F1 have similar proliferative properties but different apoptotic and oncogenic properties in vivo.
Volume: 20
Issue: 10
Pages: 3417-24
Publication
First Author: Pierce AM
Year: 1998
Journal: Proc Natl Acad Sci U S A
Title: Increased E2F1 activity induces skin tumors in mice heterozygous and nullizygous for p53.
Volume: 95
Issue: 15
Pages: 8858-63
Publication
First Author: Holmberg C
Year: 1998
Journal: Oncogene
Title: E2F-1-induced p53-independent apoptosis in transgenic mice.
Volume: 17
Issue: 2
Pages: 143-55
Publication
First Author: Fedele M
Year: 2006
Journal: Cancer Cell
Title: HMGA2 induces pituitary tumorigenesis by enhancing E2F1 activity.
Volume: 9
Issue: 6
Pages: 459-71
Publication
First Author: Costa C
Year: 2013
Journal: Oncogene
Title: E2F1 loss induces spontaneous tumour development in Rb-deficient epidermis.
Volume: 32
Issue: 24
Pages: 2937-51
Publication
First Author: Hou ST
Year: 2000
Journal: J Neurochem
Title: The transcription factor E2F1 modulates apoptosis of neurons.
Volume: 75
Issue: 1
Pages: 91-100
Publication
First Author: Conner EA
Year: 2003
Journal: Biochem Biophys Res Commun
Title: E2F1 blocks and c-Myc accelerates hepatic ploidy in transgenic mouse models.
Volume: 302
Issue: 1
Pages: 114-20
Publication
First Author: Kent LN
Year: 2017
Journal: J Clin Invest
Title: Dosage-dependent copy number gains in E2f1 and E2f3 drive hepatocellular carcinoma.
Volume: 127
Issue: 3
Pages: 830-842
Publication  
First Author: Wang B
Year: 2015
Journal: Nat Commun
Title: POH1 deubiquitylates and stabilizes E2F1 to promote tumour formation.
Volume: 6
Pages: 8704
Publication
First Author: Bartley SM
Year: 1998
Journal: Gene
Title: Characterization of the 3' untranslated region of mouse E2F1 mRNA.
Volume: 223
Issue: 1-2
Pages: 355-60
Publication
First Author: Wang L
Year: 2007
Journal: J Neurosci
Title: E2F1 works as a cell cycle suppressor in mature neurons.
Volume: 27
Issue: 46
Pages: 12555-64
Publication
First Author: Denechaud PD
Year: 2016
Journal: J Clin Invest
Title: E2F1 mediates sustained lipogenesis and contributes to hepatic steatosis.
Volume: 126
Issue: 1
Pages: 137-50
Publication
First Author: Rounbehler RJ
Year: 2002
Journal: Cancer Res
Title: Inactivation of E2f1 enhances tumorigenesis in a Myc transgenic model.
Volume: 62
Issue: 11
Pages: 3276-81
Publication  
First Author: Lu Z
Year: 2014
Journal: Nat Commun
Title: Skp2 suppresses apoptosis in Rb1-deficient tumours by limiting E2F1 activity.
Volume: 5
Pages: 3463
Publication
First Author: Berton TR
Year: 2005
Journal: Oncogene
Title: Regulation of epidermal apoptosis and DNA repair by E2F1 in response to ultraviolet B radiation.
Volume: 24
Issue: 15
Pages: 2449-60
Publication
First Author: Wu M
Year: 2014
Journal: Cardiovasc Res
Title: E2F1 suppresses cardiac neovascularization by down-regulating VEGF and PlGF expression.
Volume: 104
Issue: 3
Pages: 412-22
Publication
First Author: Chen D
Year: 2013
Journal: Cell Death Differ
Title: E2f2 induces cone photoreceptor apoptosis independent of E2f1 and E2f3.
Volume: 20
Issue: 7
Pages: 931-40
Publication
First Author: Baudino TA
Year: 2003
Journal: Mol Cell
Title: Myc-mediated proliferation and lymphomagenesis, but not apoptosis, are compromised by E2f1 loss.
Volume: 11
Issue: 4
Pages: 905-14
Publication
First Author: Carnevale J
Year: 2012
Journal: Mol Cell Biol
Title: DNA damage signals through differentially modified E2F1 molecules to induce apoptosis.
Volume: 32
Issue: 5
Pages: 900-12
Publication
First Author: Pellicano F
Year: 2018
Journal: Blood
Title: hsa-mir183/EGR1-mediated regulation of E2F1 is required for CML stem/progenitor cell survival.
Volume: 131
Issue: 14
Pages: 1532-1544
Publication
First Author: Rotgers E
Year: 2015
Journal: Andrology
Title: E2F1 controls germ cell apoptosis during the first wave of spermatogenesis.
Volume: 3
Issue: 5
Pages: 1000-14
Publication
First Author: Ting JH
Year: 2014
Journal: J Neurochem
Title: Targeted gene mutation of E2F1 evokes age-dependent synaptic disruption and behavioral deficits.
Volume: 129
Issue: 5
Pages: 850-63
Publication
First Author: Miyajima M
Year: 1996
Journal: J Neurosci Res
Title: Overexpression of E2F1 in astrocytes leads to neoplastic transformation and changes in expression of retinoblastoma family members.
Volume: 46
Issue: 1
Pages: 108-13
Publication  
First Author: Lai Q
Year: 2017
Journal: JCI Insight
Title: E2F1 inhibits circulating cholesterol clearance by regulating Pcsk9 expression in the liver.
Volume: 2
Issue: 10
Publication
First Author: Wikonkal NM
Year: 2003
Journal: Nat Cell Biol
Title: Inactivating E2f1 reverts apoptosis resistance and cancer sensitivity in Trp53-deficient mice.
Volume: 5
Issue: 7
Pages: 655-60
Publication
First Author: Zacksenhaus E
Year: 1996
Journal: EMBO J
Title: Dual mechanisms of repression of E2F1 activity by the retinoblastoma gene product.
Volume: 15
Issue: 21
Pages: 5917-27
Publication
First Author: Lin SC
Year: 2001
Journal: Oncogene
Title: The proliferative and apoptotic activities of E2F1 in the mouse retina.
Volume: 20
Issue: 48
Pages: 7073-84
Publication  
First Author: Tarangelo A
Year: 2015
Journal: Nat Commun
Title: Recruitment of Pontin/Reptin by E2f1 amplifies E2f transcriptional response during cancer progression.
Volume: 6
Pages: 10028
Publication
First Author: García I
Year: 2000
Journal: Cell Growth Differ
Title: A role for E2F1 in the induction of apoptosis during thymic negative selection.
Volume: 11
Issue: 2
Pages: 91-8
Publication
First Author: Salam MA
Year: 2004
Journal: J Immunol
Title: E2f1 mutation induces early onset of diabetes and Sjögren's syndrome in nonobese diabetic mice.
Volume: 173
Issue: 8
Pages: 4908-18
Publication
First Author: Warg LA
Year: 2012
Journal: Am J Physiol Lung Cell Mol Physiol
Title: The role of the E2F1 transcription factor in the innate immune response to systemic LPS.
Volume: 303
Issue: 5
Pages: L391-400
Publication
First Author: Biswas AK
Year: 2014
Journal: Cancer Res
Title: E2F1 responds to ultraviolet radiation by directly stimulating DNA repair and suppressing carcinogenesis.
Volume: 74
Issue: 12
Pages: 3369-77
Publication
First Author: Hsiao KM
Year: 1994
Journal: Genes Dev
Title: Multiple DNA elements are required for the growth regulation of the mouse E2F1 promoter.
Volume: 8
Issue: 13
Pages: 1526-37
Publication
First Author: Hyde RK
Year: 2002
Journal: Invest Ophthalmol Vis Sci
Title: Unique roles for E2F1 in the mouse lens in the absence of functional pRB proteins.
Volume: 43
Issue: 5
Pages: 1509-16
Publication
First Author: Iglesias-Ara A
Year: 2015
Journal: Cell Death Differ
Title: E2F1 and E2F2 prevent replicative stress and subsequent p53-dependent organ involution.
Volume: 22
Issue: 10
Pages: 1577-89
Publication
First Author: Zhu JW
Year: 1999
Journal: Cell Growth Differ
Title: A role for E2F1 in the induction of ARF, p53, and apoptosis during thymic negative selection.
Volume: 10
Issue: 12
Pages: 829-38
Publication
First Author: Zhu JW
Year: 2001
Journal: Mol Cell Biol
Title: E2F1 and E2F2 determine thresholds for antigen-induced T-cell proliferation and suppress tumorigenesis.
Volume: 21
Issue: 24
Pages: 8547-64
Publication
First Author: Pan H
Year: 1998
Journal: Mol Cell
Title: Key roles for E2F1 in signaling p53-dependent apoptosis and in cell division within developing tumors.
Volume: 2
Issue: 3
Pages: 283-92
Publication
First Author: Leng F
Year: 2018
Journal: Nat Commun
Title: Methylated DNMT1 and E2F1 are targeted for proteolysis by L3MBTL3 and CRL4DCAF5 ubiquitin ligase.
Volume: 9
Issue: 1
Pages: 1641
Publication
First Author: Qin G
Year: 2006
Journal: Proc Natl Acad Sci U S A
Title: Cell cycle regulator E2F1 modulates angiogenesis via p53-dependent transcriptional control of VEGF.
Volume: 103
Issue: 29
Pages: 11015-20
Publication
First Author: Agger K
Year: 2005
Journal: Oncogene
Title: Conditional E2F1 activation in transgenic mice causes testicular atrophy and dysplasia mimicking human CIS.
Volume: 24
Issue: 5
Pages: 780-9
Publication
First Author: Cloud JE
Year: 2002
Journal: Mol Cell Biol
Title: Mutant mouse models reveal the relative roles of E2F1 and E2F3 in vivo.
Volume: 22
Issue: 8
Pages: 2663-72
Publication
First Author: DeRyckere D
Year: 2005
Journal: J Immunol
Title: E2F1 and E2F2 are differentially required for homeostasis-driven and antigen-induced T cell proliferation in vivo.
Volume: 175
Issue: 2
Pages: 647-55
Publication
First Author: Chen D
Year: 2008
Journal: J Biol Chem
Title: E2F1 regulates the base excision repair gene XRCC1 and promotes DNA repair.
Volume: 283
Issue: 22
Pages: 15381-9
Publication
First Author: Endorf EB
Year: 2017
Journal: Arterioscler Thromb Vasc Biol
Title: Telomerase Reverse Transcriptase Deficiency Prevents Neointima Formation Through Chromatin Silencing of E2F1 Target Genes.
Volume: 37
Issue: 2
Pages: 301-311
Publication
First Author: Gao X
Year: 2004
Journal: Virology
Title: Role of cell cycle regulator E2F1 in regulating CD8 T cell responses during acute and chronic viral infection.
Volume: 324
Issue: 2
Pages: 567-76
Publication
First Author: Amasaki H
Year: 2003
Journal: Ann Anat
Title: Distributional changes of BrdU, PCNA, E2F1 and PAL31 molecules in developing murine palatal rugae.
Volume: 185
Issue: 6
Pages: 517-23
Publication
First Author: Fajas L
Year: 2004
Journal: J Clin Invest
Title: Impaired pancreatic growth, beta cell mass, and beta cell function in E2F1 (-/- )mice.
Volume: 113
Issue: 9
Pages: 1288-95
Publication
First Author: Palmero I
Year: 2002
Journal: Oncogene
Title: Activation of ARF by oncogenic stress in mouse fibroblasts is independent of E2F1 and E2F2.
Volume: 21
Issue: 19
Pages: 2939-47
Publication
First Author: Kuwako K
Year: 2004
Journal: J Biol Chem
Title: Necdin-related MAGE proteins differentially interact with the E2F1 transcription factor and the p75 neurotrophin receptor.
Volume: 279
Issue: 3
Pages: 1703-12
Publication
First Author: Hong W
Year: 2011
Journal: Biochem Biophys Res Commun
Title: Epigenetic involvement of Alien/ESET complex in thyroid hormone-mediated repression of E2F1 gene expression and cell proliferation.
Volume: 415
Issue: 4
Pages: 650-5
Publication
First Author: Jiang SX
Year: 2007
Journal: Mol Cell Biol
Title: Neuropilin-1 is a direct target of the transcription factor E2F1 during cerebral ischemia-induced neuronal death in vivo.
Volume: 27
Issue: 5
Pages: 1696-705
Publication
First Author: Magri L
Year: 2014
Journal: J Neurosci
Title: E2F1 coregulates cell cycle genes and chromatin components during the transition of oligodendrocyte progenitors from proliferation to differentiation.
Volume: 34
Issue: 4
Pages: 1481-93
Publication
First Author: Wang N
Year: 2016
Journal: PLoS One
Title: E2F1 Hinders Skin Wound Healing by Repressing Vascular Endothelial Growth Factor (VEGF) Expression, Neovascularization, and Macrophage Recruitment.
Volume: 11
Issue: 8
Pages: e0160411
Publication
First Author: Giovanni A
Year: 2000
Journal: J Biol Chem
Title: E2F1 mediates death of B-amyloid-treated cortical neurons in a manner independent of p53 and dependent on Bax and caspase 3.
Volume: 275
Issue: 16
Pages: 11553-60
Publication
First Author: Jiang Z
Year: 2000
Journal: Dev Biol
Title: E2F1 and p53 are dispensable, whereas p21(Waf1/Cip1) cooperates with Rb to restrict endoreduplication and apoptosis during skeletal myogenesis.
Volume: 227
Issue: 1
Pages: 8-41
Publication
First Author: Elena C
Year: 2010
Journal: Biochim Biophys Acta
Title: Specific interaction between E2F1 and Sp1 regulates the expression of murine CTP:phosphocholine cytidylyltransferase alpha during the S phase.
Volume: 1801
Issue: 4
Pages: 537-46
Publication
First Author: Tsume M
Year: 2012
Journal: Biochem Biophys Res Commun
Title: Brd2 is required for cell cycle exit and neuronal differentiation through the E2F1 pathway in mouse neuroepithelial cells.
Volume: 425
Issue: 4
Pages: 762-8
Publication
First Author: Sangwan M
Year: 2012
Journal: Oncogene
Title: Established and new mouse models reveal E2f1 and Cdk2 dependency of retinoblastoma, and expose effective strategies to block tumor initiation.
Volume: 31
Issue: 48
Pages: 5019-28
Publication
First Author: Hoja MR
Year: 2004
Journal: Cell Death Differ
Title: E2F1 deficiency impairs murine spermatogenesis and augments testicular degeneration in SCP3-nullizygous mice.
Volume: 11
Issue: 3
Pages: 354-6
Publication
First Author: Liu Y
Year: 2000
Journal: Oncogene
Title: E2F1 mediates ectopic proliferation and stage-specific p53-dependent apoptosis but not aberrant differentiation in the ocular lens of Rb deficient fetuses.
Volume: 19
Issue: 52
Pages: 6065-73
Publication
First Author: Jordan-Sciutto KL
Year: 1997
Journal: Exp Cell Res
Title: Reduction in fibronectin expression and alteration in cell morphology are coincident in NIH3T3 cells expressing a mutant E2F1 transcription factor.
Volume: 236
Issue: 2
Pages: 527-36
Publication
First Author: Swarnalatha M
Year: 2013
Journal: J Cell Sci
Title: Promoter occupancy of MLL1 histone methyltransferase seems to specify the proliferative and apoptotic functions of E2F1 in a tumour microenvironment.
Volume: 126
Issue: Pt 20
Pages: 4636-46
Publication
First Author: Zhang L
Year: 2012
Journal: FEBS Lett
Title: Activating cardiac E2F1 induces up-regulation of pyruvate dehydrogenase kinase 4 in mice on a short term of high fat feeding.
Volume: 586
Issue: 7
Pages: 996-1003
Publication
First Author: Chen Q
Year: 2000
Journal: Invest Ophthalmol Vis Sci
Title: Induction of cell cycle entry and cell death in postmitotic lens fiber cells by overexpression of E2F1 or E2F2.
Volume: 41
Issue: 13
Pages: 4223-31
Publication
First Author: Strachan GD
Year: 2005
Journal: Exp Neurol
Title: Chemokine- and neurotrophic factor-induced changes in E2F1 localization and phosphorylation of the retinoblastoma susceptibility gene product (pRb) occur by distinct mechanisms in murine cortical cultures.
Volume: 193
Issue: 2
Pages: 455-68
Publication
First Author: Zaragoza K
Year: 2010
Journal: Mol Cell Biol
Title: Repression of transcriptional activity of C/EBPalpha by E2F-dimerization partner complexes.
Volume: 30
Issue: 9
Pages: 2293-304
Publication
First Author: Porse BT
Year: 2001
Journal: Cell
Title: E2F repression by C/EBPalpha is required for adipogenesis and granulopoiesis in vivo.
Volume: 107
Issue: 2
Pages: 247-58
Publication
First Author: Novy M
Year: 2005
Journal: Mol Biol Cell
Title: EAPP, a novel E2F binding protein that modulates E2F-dependent transcription.
Volume: 16
Issue: 5
Pages: 2181-90
Publication
First Author: Dagnino L
Year: 1997
Journal: Mech Dev
Title: Expression patterns of the E2F family of transcription factors during mouse nervous system development.
Volume: 66
Issue: 1-2
Pages: 13-25
Publication
First Author: Conner EA
Year: 2000
Journal: Oncogene
Title: Dual functions of E2F-1 in a transgenic mouse model of liver carcinogenesis.
Volume: 19
Issue: 44
Pages: 5054-62
Publication
First Author: Tsai SY
Year: 2008
Journal: Nature
Title: Mouse development with a single E2F activator.
Volume: 454
Issue: 7208
Pages: 1137-41
UniProt Feature
Begin: 1
Description: Transcription factor E2F1
Type: chain
End: 430
GXD Expression
Probe: MGI:4839153
Assay Type: Immunohistochemistry
Annotation Date: 2010-11-19
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757727
Pattern: Single cells
Stage: TS27
Assay Id: MGI:4839209
Age: postnatal day 0
Image: 2A - E2f1
Note: Expression is present in oligodendrocytes and oligoendrocyte progenitors.
Detected: true
Specimen Num: 3
Publication
First Author: MacManus JP
Year: 1999
Journal: Neuroreport
Title: Decreased brain infarct following focal ischemia in mice lacking the transcription factor E2F1.
Volume: 10
Issue: 13
Pages: 2711-4
Publication
First Author: Cooper-Kuhn CM
Year: 2002
Journal: Mol Cell Neurosci
Title: Impaired adult neurogenesis in mice lacking the transcription factor E2F1.
Volume: 21
Issue: 2
Pages: 312-23
Publication
First Author: Palm T
Year: 2013
Journal: Nucleic Acids Res
Title: A systemic transcriptome analysis reveals the regulation of neural stem cell maintenance by an E2F1-miRNA feedback loop.
Volume: 41
Issue: 6
Pages: 3699-712
Allele
Name: transgene insertion 2, David G Johnson
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
Publication categories: ProxyCollection
Publication
First Author: Fajas L
Year: 2002
Journal: Dev Cell
Title: E2Fs regulate adipocyte differentiation.
Volume: 3
Issue: 1
Pages: 39-49
Publication
First Author: Liu K
Year: 2006
Journal: EMBO J
Title: Regulation of TopBP1 oligomerization by Akt/PKB for cell survival.
Volume: 25
Issue: 20
Pages: 4795-807
Publication
First Author: Pediconi N
Year: 2009
Journal: Mol Cell Biol
Title: hSirT1-dependent regulation of the PCAF-E2F1-p73 apoptotic pathway in response to DNA damage.
Volume: 29
Issue: 8
Pages: 1989-98
Publication
First Author: Kim JM
Year: 2011
Journal: Clin Exp Immunol
Title: Stimulation of dendritic cells with Helicobacter pylori vacuolating cytotoxin negatively regulates their maturation via the restoration of E2F1.
Volume: 166
Issue: 1
Pages: 34-45
Publication  
First Author: Slee EA
Year: 2013
Journal: Sci Rep
Title: Requirement for phosphorylation of P53 at Ser312 in suppression of chemical carcinogenesis.
Volume: 3
Pages: 3105
Publication
First Author: Blanchet E
Year: 2012
Journal: Hum Mol Genet
Title: E2F transcription factor-1 deficiency reduces pathophysiology in the mouse model of Duchenne muscular dystrophy through increased muscle oxidative metabolism.
Volume: 21
Issue: 17
Pages: 3910-7
Publication  
First Author: Wang K
Year: 2015
Journal: Nat Commun
Title: E2F1-dependent miR-421 regulates mitochondrial fragmentation and myocardial infarction by targeting Pink1.
Volume: 6
Pages: 7619