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Search results 1 to 100 out of 543 for E2f3

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Hits by Pathway

Hits by Strain

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Type Details Score
Gene
1871 | E2F3
Type: gene
Organism: human
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Gene
471865 | E2F3
Type: gene
Organism: chimpanzee
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Gene
541184 | E2F3
Type: gene
Organism: cattle
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Gene
420824 | E2F3
Type: gene
Organism: chicken
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Gene
791146 | e2f3
Type: gene
Organism: zebrafish
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Gene
713904 | E2F3
Type: gene
Organism: macaque, rhesus
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Gene
496522 | e2f3
Type: gene
Organism: frog, western clawed
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Gene
291105 | E2f3
Type: gene
Organism: rat
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Gene
488239 | E2F3
Type: gene
Organism: dog, domestic
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Protein Coding Gene
MGI:1096340 | E2f3
Type: protein_coding_gene
Organism: mouse, laboratory
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Gene
100874268 | E2F3-IT1
Type: gene
Organism: human
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GXD Expression
GXD Expression
     
Probe: MGI:7461636
Assay Type: RT-PCR
Annotation Date: 2023-04-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:7466104
Age: postnatal week 6
Specimen Label: E2F3
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:7461637
Assay Type: RT-PCR
Annotation Date: 2023-04-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:7466105
Age: postnatal week 6
Specimen Label: E2F3
Detected: true
Specimen Num: 1
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Publication
10733529 | J:65128
First Author: Humbert PO
Year: 2000
Journal: Genes Dev
Title: E2f3 is critical for normal cellular proliferation.
Volume: 14
Issue: 6
Pages: 690-703
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Publication
26549026 | J:311800
First Author: Trikha P
Year: 2016
Journal: Oncogene
Title: E2f3 in tumor macrophages promotes lung metastasis.
Volume: 35
Issue: 28
Pages: 3636-46
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Publication
19917728 | J:156401
First Author: Martinez LA
Year: 2010
Journal: Mol Cell Biol
Title: E2F3 is a mediator of DNA damage-induced apoptosis.
Volume: 30
Issue: 2
Pages: 524-36
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Publication
19029823 | J:147334
First Author: King JC
Year: 2008
Journal: Cell Cycle
Title: E2F3 plays an essential role in cardiac development and function.
Volume: 7
Issue: 23
Pages: 3775-80
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Publication
23799044 | J:204212
First Author: Zhou J
Year: 2013
Journal: PLoS One
Title: Contrasting roles of E2F2 and E2F3 in cardiac neovascularization.
Volume: 8
Issue: 6
Pages: e65755
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Publication
28134624 | J:242936
First Author: Kent LN
Year: 2017
Journal: J Clin Invest
Title: Dosage-dependent copy number gains in E2f1 and E2f3 drive hepatocellular carcinoma.
Volume: 127
Issue: 3
Pages: 830-842
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Publication
28855541 | J:255811
First Author: Gamper I
Year: 2017
Journal: Sci Rep
Title: Determination of the physiological and pathological roles of E2F3 in adult tissues.
Volume: 7
Issue: 1
Pages: 9932
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Publication
31839743 | J:283824
First Author: Kim HR
Year: 2019
Journal: Int J Med Sci
Title: Critical Roles of E2F3 in Growth and Musculo-skeletal Phenotype in Mice.
Volume: 16
Issue: 12
Pages: 1557-1563
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Publication
28979847 | J:277585
First Author: Liao Y
Year: 2017
Journal: FEBS Open Bio
Title: Rb-independent E2F3 promotes cell proliferation and alters expression of genes involved in metabolism and inflammation.
Volume: 7
Issue: 10
Pages: 1611-1621
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Publication
11230146 | J:67783
First Author: Ziebold U
Year: 2001
Journal: Genes Dev
Title: E2F3 contributes both to the inappropriate proliferation and to the apoptosis arising in Rb mutant embryos.
Volume: 15
Issue: 4
Pages: 386-91
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Publication
18663357 | J:147270
First Author: Danielian PS
Year: 2008
Journal: Oncogene
Title: E2f3a and E2f3b make overlapping but different contributions to total E2f3 activity.
Volume: 27
Issue: 51
Pages: 6561-70
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Publication
31308245 | J:277702
 
First Author: Rotgers E
Year: 2019
Journal: J Cell Sci
Title: Retinoblastoma protein represses E2F3 to maintain Sertoli cell quiescence in mouse testis.
Volume: 132
Issue: 14
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Publication
12065245 | J:77222
First Author: Saavedra HI
Year: 2002
Journal: Cell Growth Differ
Title: Specificity of E2F1, E2F2, and E2F3 in mediating phenotypes induced by loss of Rb.
Volume: 13
Issue: 5
Pages: 215-25
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Publication
11909960 | J:75765
First Author: Cloud JE
Year: 2002
Journal: Mol Cell Biol
Title: Mutant mouse models reveal the relative roles of E2F1 and E2F3 in vivo.
Volume: 22
Issue: 8
Pages: 2663-72
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Publication
17210634 | J:121512
First Author: Parisi T
Year: 2007
Journal: Mol Cell Biol
Title: Selective requirements for E2f3 in the development and tumorigenicity of Rb-deficient chimeric tissues.
Volume: 27
Issue: 6
Pages: 2283-93
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Publication
23603666 | J:330474
 
First Author: Zhou J
Year: 2013
Journal: J Mol Cell Cardiol
Title: Contrasting roles of E2F2 and E2F3 in endothelial cell growth and ischemic angiogenesis.
Volume: 60
Pages: 68-71
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Publication
24901045 | J:267321
 
First Author: Rotgers E
Year: 2014
Journal: Cell Death Dis
Title: Retinoblastoma protein (RB) interacts with E2F3 to control terminal differentiation of Sertoli cells.
Volume: 5
Pages: e1274
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Publication
15175242 | J:90855
First Author: Aslanian A
Year: 2004
Journal: Genes Dev
Title: Repression of the Arf tumor suppressor by E2F3 is required for normal cell cycle kinetics.
Volume: 18
Issue: 12
Pages: 1413-22
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Publication
10779352 | J:65132
First Author: Leone G
Year: 2000
Journal: Mol Cell Biol
Title: Identification of a novel E2F3 product suggests a mechanism for determining specificity of repression by Rb proteins.
Volume: 20
Issue: 10
Pages: 3626-32
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Publication
17925491 | J:130103
First Author: Eiring AM
Year: 2008
Journal: Blood
Title: Identification of novel posttranscriptional targets of the BCR/ABL oncoprotein by ribonomics: requirement of E2F3 for BCR/ABL leukemogenesis.
Volume: 111
Issue: 2
Pages: 816-28
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Publication
29330306 | J:262772
First Author: Liao Y
Year: 2018
Journal: J Biol Chem
Title: An Rb family-independent E2F3 transcription factor variant impairs STAT5 signaling and mammary gland remodeling during pregnancy in mice.
Volume: 293
Issue: 9
Pages: 3156-3167
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Publication
17167174 | J:117696
First Author: Timmers C
Year: 2007
Journal: Mol Cell Biol
Title: E2f1, E2f2, and E2f3 control E2F target expression and cellular proliferation via a p53-dependent negative feedback loop.
Volume: 27
Issue: 1
Pages: 65-78
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Publication
17008321 | J:117634
First Author: Sharma N
Year: 2006
Journal: J Biol Chem
Title: Control of the p53-p21CIP1 Axis by E2f1, E2f2, and E2f3 is essential for G1/S progression and cellular transformation.
Volume: 281
Issue: 47
Pages: 36124-31
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GXD Expression
GXD Expression
   
Probe: MGI:6171659
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689419
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:6190166
Age: embryonic day 11.5
Specimen Label: Table S2 - E11.5 - E2f3
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:6171659
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689421
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:6190166
Age: embryonic day 13.5
Specimen Label: Table S2 - E13.5 - E2f3
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:6171659
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689424
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:6190166
Age: embryonic day 15.5
Specimen Label: Table S2 - E15.5 - E2f3
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:6171659
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689426
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:6190166
Age: embryonic day 18.5
Specimen Label: Table S2 - E18.5 - E2f3
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:6171659
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6190166
Age: postnatal day 4
Specimen Label: Table S2 - P4 - E2f3
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
   
Probe: MGI:6171659
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6190166
Age: postnatal day 14
Specimen Label: Table S2 - P14 - E2f3
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
   
Probe: MGI:6171659
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6190166
Age: postnatal day 28
Specimen Label: Table S2 - P28 - E2f3
Detected: true
Specimen Num: 7
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Publication
12944480 | J:85441
First Author: Ziebold U
Year: 2003
Journal: Mol Cell Biol
Title: E2F3 loss has opposing effects on different pRB-deficient tumors, resulting in suppression of pituitary tumors but metastasis of medullary thyroid carcinomas.
Volume: 23
Issue: 18
Pages: 6542-52
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Publication
16340309 | J:107082
First Author: Paulson QX
Year: 2006
Journal: Cell Cycle
Title: E2F3a stimulates proliferation, p53-independent apoptosis and carcinogenesis in a transgenic mouse model.
Volume: 5
Issue: 2
Pages: 184-90
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Publication
20176812 | J:161707
First Author: Zaragoza K
Year: 2010
Journal: Mol Cell Biol
Title: Repression of transcriptional activity of C/EBPalpha by E2F-dimerization partner complexes.
Volume: 30
Issue: 9
Pages: 2293-304
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Allele
Tg(KRT5-E2F3)3.2Dgj | MGI:5302003
Name: transgene insertion 3.2, David G Johnson
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
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Publication
15716352 | J:100168
First Author: Novy M
Year: 2005
Journal: Mol Biol Cell
Title: EAPP, a novel E2F binding protein that modulates E2F-dependent transcription.
Volume: 16
Issue: 5
Pages: 2181-90
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Publication
9376316 | J:42771
First Author: Dagnino L
Year: 1997
Journal: Mech Dev
Title: Expression patterns of the E2F family of transcription factors during mouse nervous system development.
Volume: 66
Issue: 1-2
Pages: 13-25
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Publication
9149906 | J:40858
First Author: Dagnino L
Year: 1997
Journal: Cell Growth Differ
Title: Expression patterns of the E2F family of transcription factors during murine epithelial development.
Volume: 8
Issue: 5
Pages: 553-63
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Publication
18469863 | J:138672
First Author: Paulson QX
Year: 2008
Journal: Oncogene
Title: Transgenic expression of E2F3a causes DNA damage leading to ATM-dependent apoptosis.
Volume: 27
Issue: 36
Pages: 4954-61
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Publication
15767672 | J:97665
First Author: Lazzerini Denchi E
Year: 2005
Journal: Mol Cell Biol
Title: Deregulated E2F activity induces hyperplasia and senescence-like features in the mouse pituitary gland.
Volume: 25
Issue: 7
Pages: 2660-72
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Publication
34873170 | J:316839
First Author: Liu Z
Year: 2021
Journal: Cell Death Dis
Title: Matrix stiffness modulates hepatic stellate cell activation into tumor-promoting myofibroblasts via E2F3-dependent signaling and regulates malignant progression.
Volume: 12
Issue: 12
Pages: 1134
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Publication
15976820 | J:99576
First Author: Lazzerini Denchi E
Year: 2005
Journal: EMBO Rep
Title: E2F1 is crucial for E2F-dependent apoptosis.
Volume: 6
Issue: 7
Pages: 661-8
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Publication
11511364 | J:75726
First Author: Leone G
Year: 2001
Journal: Mol Cell
Title: Myc requires distinct E2F activities to induce S phase and apoptosis.
Volume: 8
Issue: 1
Pages: 105-13
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Publication
20308562 | J:159318
First Author: Biswas S
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Hypoxia inducible microRNA 210 attenuates keratinocyte proliferation and impairs closure in a murine model of ischemic wounds.
Volume: 107
Issue: 15
Pages: 6976-81
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Publication
23530192 | J:196194
First Author: Lui JC
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Evidence that Igf2 down-regulation in postnatal tissues and up-regulation in malignancies is driven by transcription factor E2f3.
Volume: 110
Issue: 15
Pages: 6181-6
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Publication
26192440 | J:227295
First Author: Liu H
Year: 2015
Journal: Nat Cell Biol
Title: Redeployment of Myc and E2f1-3 drives Rb-deficient cell cycles.
Volume: 17
Issue: 8
Pages: 1036-48
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Publication
23146901 | J:203239
First Author: Landman AS
Year: 2013
Journal: Oncogene
Title: Loss of pRB and p107 disrupts cartilage development and promotes enchondroma formation.
Volume: 32
Issue: 40
Pages: 4798-805
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Publication
11719808 | J:73374
First Author: Wu L
Year: 2001
Journal: Nature
Title: The E2F1-3 transcription factors are essential for cellular proliferation.
Volume: 414
Issue: 6862
Pages: 457-62
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Publication
24934442 | J:224271
First Author: Hollern DP
Year: 2014
Journal: Mol Cell Biol
Title: The E2F transcription factors regulate tumor development and metastasis in a mouse model of metastatic breast cancer.
Volume: 34
Issue: 17
Pages: 3229-43
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Publication
21245101 | J:169307
First Author: Fujiwara K
Year: 2011
Journal: Cancer Res
Title: Prediction and genetic demonstration of a role for activator E2Fs in Myc-induced tumors.
Volume: 71
Issue: 5
Pages: 1924-32
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Publication
16180235 | J:103456
First Author: Orlic M
Year: 2006
Journal: Genes Chromosomes Cancer
Title: Expression analysis of 6p22 genomic gain in retinoblastoma.
Volume: 45
Issue: 1
Pages: 72-82
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Publication
20404092 | J:162674
First Author: Bueno MJ
Year: 2010
Journal: Mol Cell Biol
Title: Multiple E2F-induced microRNAs prevent replicative stress in response to mitogenic signaling.
Volume: 30
Issue: 12
Pages: 2983-95
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Publication
23499385 | J:196454
First Author: Julian LM
Year: 2013
Journal: Cell Stem Cell
Title: Opposing regulation of Sox2 by cell-cycle effectors E2f3a and E2f3b in neural stem cells.
Volume: 12
Issue: 4
Pages: 440-52
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Publication
19015245 | J:144747
First Author: Chong JL
Year: 2009
Journal: Mol Cell Biol
Title: E2f3a and E2f3b contribute to the control of cell proliferation and mouse development.
Volume: 29
Issue: 2
Pages: 414-24
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Publication
20016602 | J:155799
First Author: Chong JL
Year: 2009
Journal: Nature
Title: E2f1-3 switch from activators in progenitor cells to repressors in differentiating cells.
Volume: 462
Issue: 7275
Pages: 930-4
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Publication
24362522 | J:218638
First Author: Andrechek ER
Year: 2015
Journal: Oncogene
Title: HER2/Neu tumorigenesis and metastasis is regulated by E2F activator transcription factors.
Volume: 34
Issue: 2
Pages: 217-25
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Publication
36276637 | J:330592
First Author: Yang X
Year: 2022
Journal: Theranostics
Title: Identifying the E2F3-MEX3A-KLF4 signaling axis that sustains cancer cells in undifferentiated and proliferative state.
Volume: 12
Issue: 16
Pages: 6865-6882
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UniProt Feature
UniProt Feature
Begin: 1
Description: Transcription factor E2F3
Type: chain
End: 457
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Publication
18594513 | J:138289
First Author: Tsai SY
Year: 2008
Journal: Nature
Title: Mouse development with a single E2F activator.
Volume: 454
Issue: 7208
Pages: 1137-41
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Publication
17881568 | J:125304
First Author: Opavsky R
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: Specific tumor suppressor function for E2F2 in Myc-induced T cell lymphomagenesis.
Volume: 104
Issue: 39
Pages: 15400-5
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Publication
17608565 | J:124204
First Author: Chen D
Year: 2007
Journal: PLoS Biol
Title: Rb-mediated neuronal differentiation through cell-cycle-independent regulation of E2f3a.
Volume: 5
Issue: 7
Pages: e179
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Publication
24276244 | J:218645
First Author: Wu L
Year: 2015
Journal: Oncogene
Title: Selective roles of E2Fs for ErbB2- and Myc-mediated mammary tumorigenesis.
Volume: 34
Issue: 1
Pages: 119-28
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Publication
21059867 | J:170280
First Author: Andrusiak MG
Year: 2011
Journal: Mol Cell Biol
Title: Rb/E2F regulates expression of neogenin during neuronal migration.
Volume: 31
Issue: 2
Pages: 238-47
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Publication
8657141 | J:125251
First Author: Karlseder J
Year: 1996
Journal: Mol Cell Biol
Title: Interaction of Sp1 with the growth- and cell cycle-regulated transcription factor E2F.
Volume: 16
Issue: 4
Pages: 1659-67
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Publication
17210791 | J:117307
First Author: Wenzel PL
Year: 2007
Journal: Genes Dev
Title: Rb is critical in a mammalian tissue stem cell population.
Volume: 21
Issue: 1
Pages: 85-97
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Publication
17452454 | J:122733
First Author: McClellan KA
Year: 2007
Journal: Mol Cell Biol
Title: Unique requirement for Rb/E2F3 in neuronal migration: evidence for cell cycle-independent functions.
Volume: 27
Issue: 13
Pages: 4825-43
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Publication
19564414 | J:152616
First Author: McClellan KA
Year: 2009
Journal: Mol Cell Biol
Title: The p107/E2F pathway regulates fibroblast growth factor 2 responsiveness in neural precursor cells.
Volume: 29
Issue: 17
Pages: 4701-13
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Publication
21185283 | J:170580
First Author: Wenzel PL
Year: 2011
Journal: Dev Biol
Title: Cell proliferation in the absence of E2F1-3.
Volume: 351
Issue: 1
Pages: 35-45
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Publication
19749980 | J:154120
First Author: Rempel RE
Year: 2009
Journal: PLoS Genet
Title: A role for E2F activities in determining the fate of Myc-induced lymphomagenesis.
Volume: 5
Issue: 9
Pages: e1000640
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Publication
22993445 | J:188279
First Author: Peng C
Year: 2012
Journal: J Neurosci
Title: A unilateral negative feedback loop between miR-200 microRNAs and Sox2/E2F3 controls neural progenitor cell-cycle exit and differentiation.
Volume: 32
Issue: 38
Pages: 13292-308
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Protein Coding Gene
MGP_CAROLIEiJ_G0018388 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0020411 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0020366 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0020343 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0020361 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0020164 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_1096340 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0020797 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0019681 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0020120 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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•
•
•
Protein Coding Gene
MGP_DBA2J_G0020242 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_FVBNJ_G0020227 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_LPJ_G0020319 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_NODShiLtJ_G0020253 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_NZOHlLtJ_G0020838 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_PWKPhJ_G0019436 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_WSBEiJ_G0019743 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_PahariEiJ_G0019453 | -
Type: protein_coding_gene
Organism: Mus pahari
•
•
•
•
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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