Type |
Details |
Score |
Gene |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Publication |
First Author: |
O'Reilly MA |
Year: |
2012 |
Journal: |
Am J Pathol |
Title: |
Neonatal oxygen increases sensitivity to influenza A virus infection in adult mice by suppressing epithelial expression of Ear1. |
Volume: |
181 |
Issue: |
2 |
Pages: |
441-51 |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus spretus |
|
•
•
•
•
•
|
Publication |
First Author: |
Larson KA |
Year: |
1996 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Two highly homologous ribonuclease genes expressed in mouse eosinophils identify a larger subgroup of the mammalian ribonuclease superfamily. |
Volume: |
93 |
Issue: |
22 |
Pages: |
12370-5 |
|
•
•
•
•
•
|
Publication |
First Author: |
Cho S |
Year: |
2005 |
Journal: |
Genomics |
Title: |
The ribonuclease A superfamily of mammals and birds: identifying new members and tracing evolutionary histories. |
Volume: |
85 |
Issue: |
2 |
Pages: |
208-20 |
|
•
•
•
•
•
|
Publication |
First Author: |
Singhania NA |
Year: |
1999 |
Journal: |
J Mol Evol |
Title: |
Rapid evolution of the ribonuclease A superfamily: adaptive expansion of independent gene clusters in rats and mice. |
Volume: |
49 |
Issue: |
6 |
Pages: |
721-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Dyer KD |
Year: |
2004 |
Journal: |
Mamm Genome |
Title: |
Identification of a purine-rich intronic enhancer element in the mouse eosinophil-associated ribonuclease 2 (mEar 2) gene. |
Volume: |
15 |
Issue: |
2 |
Pages: |
126-34 |
|
•
•
•
•
•
|
Publication |
First Author: |
Chen JQ |
Year: |
2015 |
Journal: |
PLoS One |
Title: |
Abnormal Mammary Development in 129:STAT1-Null Mice is Stroma-Dependent. |
Volume: |
10 |
Issue: |
6 |
Pages: |
e0129895 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bettigole SE |
Year: |
2015 |
Journal: |
Nat Immunol |
Title: |
The transcription factor XBP1 is selectively required for eosinophil differentiation. |
Volume: |
16 |
Issue: |
8 |
Pages: |
829-37 |
|
•
•
•
•
•
|
Publication |
First Author: |
The Gene Ontology Consortium |
Year: |
2010 |
|
Title: |
Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
UniProt-GOA |
Year: |
2012 |
|
Title: |
Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
DDB, FB, MGI, GOA, ZFIN curators |
Year: |
2001 |
|
Title: |
Gene Ontology annotation through association of InterPro records with GO terms |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas |
Year: |
2010 |
|
Title: |
Annotation inferences using phylogenetic trees |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Database and National Center for Biotechnology Information |
Year: |
2000 |
Journal: |
Database Release |
Title: |
Entrez Gene Load |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI) |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Consensus CDS project |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Group |
Year: |
2003 |
Journal: |
Database Procedure |
Title: |
Automatic Encodes (AutoE) Reference |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Bairoch A |
Year: |
1999 |
Journal: |
Database Release |
Title: |
SWISS-PROT Annotated protein sequence database |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2). |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics |
Year: |
2010 |
Journal: |
Database Release |
Title: |
Protein Ontology Association Load. |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and loading genome assembly coordinates from NCBI annotations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform |
|
|
|
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
615
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Kota J |
Year: |
2007 |
Journal: |
Genetics |
Title: |
Ssh4, Rcr2 and Rcr1 affect plasma membrane transporter activity in Saccharomyces cerevisiae. |
Volume: |
175 |
Issue: |
4 |
Pages: |
1681-94 |
|
•
•
•
•
•
|
Publication |
First Author: |
Léon S |
Year: |
2008 |
Journal: |
Mol Biol Cell |
Title: |
Ear1p and Ssh4p are new adaptors of the ubiquitin ligase Rsp5p for cargo ubiquitylation and sorting at multivesicular bodies. |
Volume: |
19 |
Issue: |
6 |
Pages: |
2379-88 |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Domain |
Description: |
This entry represents the SPRY domain found in Ssh4 (suppressor of SHR3 null mutation protein 4) and similar proteins. Ssh4 is a component of the endosome-vacuole trafficking pathway that regulates nutrient transport and may be involved in processes determining whether plasma membrane proteins are degraded or routed to the plasma membrane []. The SPRY domain in Ssh4 may be involved in cargo recognition, either directly or by combination with other adaptors, possibly leading to a higher selectivity. In yeast, Ssh4 and the homologous protein Ear1 (endosomal adapter of RSP5) recruit Rsp5p, an essential ubiquitin ligase of the Nedd4 family, and assist it in its function at multivesicular bodies by directing the ubiquitylation of specific cargoes []. |
|
•
•
•
•
•
|