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Search results 1 to 89 out of 89 for Edem3

0.899s

Categories

Hits by Category

Hits by Strain

Type Details Score
Gene
80267 | EDEM3
Type: gene
Organism: human
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Gene
100145667 | edem3
Type: gene
Organism: frog, western clawed
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Gene
289085 | Edem3
Type: gene
Organism: rat
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Gene
457578 | EDEM3
Type: gene
Organism: chimpanzee
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Gene
480040 | EDEM3
Type: gene
Organism: dog, domestic
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Gene
519058 | EDEM3
Type: gene
Organism: cattle
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Gene
424450 | EDEM3
Type: gene
Organism: chicken
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Gene
559811 | edem3
Type: gene
Organism: zebrafish
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Gene
714475 | EDEM3
Type: gene
Organism: macaque, rhesus
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Protein Coding Gene
MGI:1914217 | Edem3
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
32213464 | J:312845
First Author: Xu YX
Year: 2020
Journal: iScience
Title: EDEM3 Modulates Plasma Triglyceride Level through Its Regulation of LRP1 Expression.
Volume: 23
Issue: 4
Pages: 100973
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Publication
16431915 | J:111585
First Author: Hirao K
Year: 2006
Journal: J Biol Chem
Title: EDEM3, a soluble EDEM homolog, enhances glycoprotein endoplasmic reticulum-associated degradation and mannose trimming.
Volume: 281
Issue: 14
Pages: 9650-8
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Protein Coding Gene
MGP_CAROLIEiJ_G0014696 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0016584 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0016566 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0016531 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0016526 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0016351 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_1914217 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0016987 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0015930 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0016325 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0016431 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0016429 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0016502 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0016455 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0017023 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0015716 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0015993 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0027932 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0015503 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
- | J:94077
     
First Author: Mutant Mouse Regional Resource Centers
Year: 2004
Journal: Unpublished
Title: Information obtained from the Mutant Mouse Regional Resource Centers (MMRRC)
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Publication
- | J:342601
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniPathway vocabulary mapping
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Publication
- | J:346132
       
First Author: The Gene Ontology Consortium
Year: 2016
Title: Automatic assignment of GO terms using logical inference, based on on inter-ontology links
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Publication
12520002 | J:91812
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
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Publication
- | J:204739
     
First Author: International Knockout Mouse Consortium
Year: 2014
Journal: Database Download
Title: MGI download of modified allele data from IKMC and creation of new knockout alleles
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Publication
- | J:211773
     
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
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Publication
- | J:157065
     
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
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Publication
- | J:72247
       
First Author: DDB, FB, MGI, GOA, ZFIN curators
Year: 2001
Title: Gene Ontology annotation through association of InterPro records with GO terms
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
38355793 | J:345621
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Protein
Q8R1X5
Organism: Mus musculus/domesticus
Length: 56  
Fragment?: true
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Protein
Q2HXL6
Organism: Mus musculus/domesticus
Length: 931  
Fragment?: false
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Interaction Experiment
Manica G (2021)
Description: EDEM3 Domains Cooperate to Perform Its Overall Cell Functioning.
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Publication
33671632 | -
 
First Author: Manica G
Year: 2021
Journal: Int J Mol Sci
Title: EDEM3 Domains Cooperate to Perform Its Overall Cell Functioning.
Volume: 22
Issue: 4
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Publication
17499246 | -
First Author: Olivari S
Year: 2007
Journal: FEBS Lett
Title: Glycoprotein folding and the role of EDEM1, EDEM2 and EDEM3 in degradation of folding-defective glycoproteins.
Volume: 581
Issue: 19
Pages: 3658-64
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Publication
34143952 | -
First Author: Polla DL
Year: 2021
Journal: Am J Hum Genet
Title: Bi-allelic variants in the ER quality-control mannosidase gene EDEM3 cause a congenital disorder of glycosylation.
Volume: 108
Issue: 7
Pages: 1342-1349
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Protein Domain
IPR037322 | EDEM3_PA
Type: Domain
Description: EDEM3 is involved in endoplasmic reticulum-associated degradation (ERAD). It accelerates the glycoprotein degradation by catalyzing mannose trimming from Man8GlcNAc2 to Man7GlcNAc2 in the N-glycans [].This entry represents the PA (protease associated) domain of EDEM3. The function of this domain is not clear.
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Publication
25092655 | -
First Author: Ninagawa S
Year: 2014
Journal: J Cell Biol
Title: EDEM2 initiates mammalian glycoprotein ERAD by catalyzing the first mannose trimming step.
Volume: 206
Issue: 3
Pages: 347-56
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Publication
27053108 | -
First Author: Pfeiffer A
Year: 2016
Journal: J Biol Chem
Title: A Complex of Htm1 and the Oxidoreductase Pdi1 Accelerates Degradation of Misfolded Glycoproteins.
Volume: 291
Issue: 23
Pages: 12195-207
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Publication
19524542 | -
First Author: Cormier JH
Year: 2009
Journal: Mol Cell
Title: EDEM1 recognition and delivery of misfolded proteins to the SEL1L-containing ERAD complex.
Volume: 34
Issue: 5
Pages: 627-33
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Publication
24737672 | -
First Author: Hüttner S
Year: 2014
Journal: Plant Cell
Title: Arabidopsis Class I α-Mannosidases MNS4 and MNS5 Are Involved in Endoplasmic Reticulum-Associated Degradation of Misfolded Glycoproteins.
Volume: 26
Issue: 4
Pages: 1712-1728
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Protein Domain
IPR044674 | EDEM1/2/3
Type: Family
Description: This entry represents a group of alpha-1,2-specific exomannosidases that are involved in endoplasmic reticulum-associated degradation (ERAD), including EDEM1/2/3 from humans, Mnl1 from yeasts and MNS4/5 from Arabidopsis. Mnl1 forms a complex with Pdi1 to process unfolded protein-bound Man8GlcNAc2 oligosaccharides to Man7GlcNAc2, promoting degradation in unfolded protein response []. In humans, mannose trimming from Man8GlcNAc2 to Man7GlcNAc2 is performed mainly by EDEM3 and to a lesser extent by EDEM1, while EDEM2 catalyses the first mannose trimming step from Man9GlcNAc2 []. EDEM1 has been shown to recognise and deliver misfolded proteins to the SEL1L-containing ERAD complex []. MNS4/5 function in the formation of unique N-glycan structures that are specifically recognized by components of the endoplasmic reticulum-associated degradation (ERAD) machinery, which leads to the degradation of misfolded glycoproteins [].
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Publication
20065073 | J:222679
First Author: Hosokawa N
Year: 2010
Journal: Glycobiology
Title: EDEM1 accelerates the trimming of alpha1,2-linked mannose on the C branch of N-glycans.
Volume: 20
Issue: 5
Pages: 567-75
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Protein
B7ZNP0
Organism: Mus musculus/domesticus
Length: 913  
Fragment?: false
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Protein
A0A087WQK5
Organism: Mus musculus/domesticus
Length: 917  
Fragment?: false
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Protein
A0A087WR24
Organism: Mus musculus/domesticus
Length: 947  
Fragment?: false
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Protein
B7ZNN9
Organism: Mus musculus/domesticus
Length: 917  
Fragment?: false
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Protein
Q925U4
Organism: Mus musculus/domesticus
Length: 652  
Fragment?: false
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Protein
Q8BJT9
Organism: Mus musculus/domesticus
Length: 577  
Fragment?: false
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Protein
Q6ZQG3
Organism: Mus musculus/domesticus
Length: 674  
Fragment?: true
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Protein
Q8BYV2
Organism: Mus musculus/domesticus
Length: 539  
Fragment?: true
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Protein
Q8C0J7
Organism: Mus musculus/domesticus
Length: 539  
Fragment?: false
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Protein
Q3UX12
Organism: Mus musculus/domesticus
Length: 306  
Fragment?: true
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Protein
A0A0N4SV08
Organism: Mus musculus/domesticus
Length: 539  
Fragment?: false
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Protein
Q3U9S2
Organism: Mus musculus/domesticus
Length: 652  
Fragment?: false
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Publication
15489334 | -
First Author: Gerhard DS
Year: 2004
Journal: Genome Res
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Volume: 14
Issue: 10B
Pages: 2121-7
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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