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Search results 1 to 100 out of 135 for Eef2k

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0.019s
Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: chimpanzee
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: zebrafish
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: dog, domestic
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Publication
First Author: Chu HP
Year: 2014
Journal: Dev Cell
Title: Germline quality control: eEF2K stands guard to eliminate defective oocytes.
Volume: 28
Issue: 5
Pages: 561-572
Publication
First Author: Gildish I
Year: 2012
Journal: Learn Mem
Title: Impaired associative taste learning and abnormal brain activation in kinase-defective eEF2K mice.
Volume: 19
Issue: 3
Pages: 116-25
Publication
First Author: Jan A
Year: 2017
Journal: Acta Neuropathol
Title: eEF2K inhibition blocks Aβ42 neurotoxicity by promoting an NRF2 antioxidant response.
Volume: 133
Issue: 1
Pages: 101-119
Publication
First Author: Smith PR
Year: 2021
Journal: Nat Commun
Title: Functionally distinct roles for eEF2K in the control of ribosome availability and p-body abundance.
Volume: 12
Issue: 1
Pages: 6789
Publication
First Author: Feng T
Year: 2021
Journal: Transl Androl Urol
Title: Eef2k is not required for fertility in male mice.
Volume: 10
Issue: 5
Pages: 1988-1999
Publication
First Author: Zhang P
Year: 2014
Journal: Can J Cardiol
Title: Impairing eukaryotic elongation factor 2 kinase activity decreases atherosclerotic plaque formation.
Volume: 30
Issue: 12
Pages: 1684-8
Publication
First Author: Beckelman BC
Year: 2019
Journal: J Clin Invest
Title: Genetic reduction of eEF2 kinase alleviates pathophysiology in Alzheimer's disease model mice.
Volume: 129
Issue: 2
Pages: 820-833
Publication
First Author: Liao Y
Year: 2016
Journal: J Biol Chem
Title: Paradoxical Roles of Elongation Factor-2 Kinase in Stem Cell Survival.
Volume: 291
Issue: 37
Pages: 19545-57
Publication
First Author: Wang X
Year: 2015
Journal: Biochem J
Title: Regulated stability of eukaryotic elongation factor 2 kinase requires intrinsic but not ongoing activity.
Volume: 467
Issue: 2
Pages: 321-31
Publication
First Author: Xie J
Year: 2019
Journal: J Biol Chem
Title: Ablation of elongation factor 2 kinase enhances heat-shock protein 90 chaperone expression and protects cells under proteotoxic stress.
Volume: 294
Issue: 18
Pages: 7169-7176
Publication
First Author: Adaikkan C
Year: 2018
Journal: Biol Psychiatry
Title: Calcium/Calmodulin-Dependent Protein Kinase II and Eukaryotic Elongation Factor 2 Kinase Pathways Mediate the Antidepressant Action of Ketamine.
Volume: 84
Issue: 1
Pages: 65-75
Publication
First Author: Suzuki K
Year: 2021
Journal: Cell Rep
Title: Convergence of distinct signaling pathways on synaptic scaling to trigger rapid antidepressant action.
Volume: 37
Issue: 5
Pages: 109918
Publication
First Author: Heise C
Year: 2017
Journal: Cereb Cortex
Title: eEF2K/eEF2 Pathway Controls the Excitation/Inhibition Balance and Susceptibility to Epileptic Seizures.
Volume: 27
Issue: 3
Pages: 2226-2248
Publication
First Author: Park S
Year: 2008
Journal: Neuron
Title: Elongation factor 2 and fragile X mental retardation protein control the dynamic translation of Arc/Arg3.1 essential for mGluR-LTD.
Volume: 59
Issue: 1
Pages: 70-83
Publication  
First Author: Yang W
Year: 2021
Journal: Neurobiol Aging
Title: Suppression of the kinase for elongation factor 2 alleviates mGluR-LTD impairments in a mouse model of Alzheimer's disease.
Volume: 98
Pages: 225-230
Publication  
First Author: Gosrani SP
Year: 2020
Journal: Neurobiol Aging
Title: Repression of eEF2 kinase improves deficits in novel object recognition memory in aged mice.
Volume: 95
Pages: 154-160
Publication
First Author: Moore CE
Year: 2015
Journal: Mol Cell Biol
Title: Elongation Factor 2 Kinase Is Regulated by Proline Hydroxylation and Protects Cells during Hypoxia.
Volume: 35
Issue: 10
Pages: 1788-804
Publication
First Author: Ponzoni L
Year: 2019
Journal: Genes Brain Behav
Title: Different attentional dysfunctions in eEF2K-/- , IL1RAPL1-/- and SHANK3Δ11-/- mice.
Volume: 18
Issue: 5
Pages: e12563
Publication
First Author: Beretta S
Year: 2022
Journal: Mol Autism
Title: Rescuing epileptic and behavioral alterations in a Dravet syndrome mouse model by inhibiting eukaryotic elongation factor 2 kinase (eEF2K).
Volume: 13
Issue: 1
Pages: 1
Publication    
First Author: Knight JR
Year: 2021
Journal: Elife
Title: Rpl24Bst mutation suppresses colorectal cancer by promoting eEF2 phosphorylation via eEF2K.
Volume: 10
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Ryazanov AG
Year: 1997
Journal: Proc Natl Acad Sci U S A
Title: Identification of a new class of protein kinases represented by eukaryotic elongation factor-2 kinase.
Volume: 94
Issue: 10
Pages: 4884-9
Publication  
First Author: Crawford DC
Year: 2017
Journal: Nat Commun
Title: Selective molecular impairment of spontaneous neurotransmission modulates synaptic efficacy.
Volume: 8
Pages: 14436
Publication
First Author: Khan AA
Year: 2010
Journal: Am J Pathol
Title: Resveratrol regulates pathologic angiogenesis by a eukaryotic elongation factor-2 kinase-regulated pathway.
Volume: 177
Issue: 1
Pages: 481-92
Publication  
First Author: David O
Year: 2020
Journal: Front Mol Neurosci
Title: D1 Dopamine Receptor Activation Induces Neuronal eEF2 Pathway-Dependent Protein Synthesis.
Volume: 13
Pages: 67
Publication
First Author: Gschwendt M
Year: 1994
Journal: FEBS Lett
Title: Elongation factor-2 kinase: effective inhibition by the novel protein kinase inhibitor rottlerin and relative insensitivity towards staurosporine.
Volume: 338
Issue: 1
Pages: 85-8
Publication
First Author: Boyce M
Year: 2008
Journal: Cell Death Differ
Title: A pharmacoproteomic approach implicates eukaryotic elongation factor 2 kinase in ER stress-induced cell death.
Volume: 15
Issue: 3
Pages: 589-99
GXD Expression      
Probe: MGI:3836758
Assay Type: Northern blot
Annotation Date: 2009-03-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689421
Stage: TS21
Assay Id: MGI:3836765
Age: embryonic day 13.0
Specimen Label: E13
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:3836758
Assay Type: Northern blot
Annotation Date: 2009-03-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689423
Stage: TS23
Assay Id: MGI:3836765
Age: embryonic day 15.0
Specimen Label: E15
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:3836758
Assay Type: Northern blot
Annotation Date: 2009-03-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689426
Stage: TS26
Assay Id: MGI:3836765
Age: embryonic day 18.0
Specimen Label: E18
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:3836758
Assay Type: Northern blot
Annotation Date: 2009-03-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:3836765
Age: postnatal day 5
Specimen Label: P5
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:3836758
Assay Type: Northern blot
Annotation Date: 2009-03-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:3836765
Age: postnatal day 10
Specimen Label: P10
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:3836758
Assay Type: Northern blot
Annotation Date: 2009-03-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:3836765
Age: postnatal day 15
Specimen Label: P15
Detected: true
Specimen Num: 6
GXD Expression      
Probe: MGI:3836758
Assay Type: Northern blot
Annotation Date: 2009-03-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:3836765
Age: postnatal day 20
Specimen Label: P20
Detected: true
Specimen Num: 7
GXD Expression      
Probe: MGI:3836758
Assay Type: Northern blot
Annotation Date: 2009-03-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:3836765
Age: postnatal day 50
Specimen Label: P50
Detected: true
Specimen Num: 8
GXD Expression    
Probe: MGI:3836762
Assay Type: RNA in situ
Annotation Date: 2009-03-23
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1760627
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:3836768
Age: postnatal day 0
Specimen Label: 2C
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:3836762
Assay Type: RNA in situ
Annotation Date: 2009-03-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3521928
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:3836768
Age: postnatal day 5
Note: Expression was detected in both external and internal granule cell layers. Staining was more evident in the internal granule cell layer.
Specimen Label: 2D
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:3836762
Assay Type: RNA in situ
Annotation Date: 2009-03-23
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3271123
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:3836768
Age: embryonic day 15.0
Specimen Label: 2B
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:3836762
Assay Type: RNA in situ
Annotation Date: 2009-03-23
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3592728
Stage: TS28
Assay Id: MGI:3836768
Age: postnatal day 50
Specimen Label: 2E
Detected: false
Specimen Num: 5
GXD Expression    
Probe: MGI:3836762
Assay Type: RNA in situ
Annotation Date: 2009-03-23
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1754427
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:3836768
Age: postnatal day 0
Specimen Label: 2C
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:3836762
Assay Type: RNA in situ
Annotation Date: 2009-03-23
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1754428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:3836768
Age: postnatal day 5
Specimen Label: 2D
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:3836762
Assay Type: RNA in situ
Annotation Date: 2009-03-23
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1754428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:3836768
Age: postnatal day 50
Specimen Label: 2E
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:3836762
Assay Type: RNA in situ
Annotation Date: 2009-03-23
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3540927
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:3836768
Age: postnatal day 0
Specimen Label: 2C
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:3836762
Assay Type: RNA in situ
Annotation Date: 2009-03-23
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3540928
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:3836768
Age: postnatal day 5
Specimen Label: 2D
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:3836762
Assay Type: RNA in situ
Annotation Date: 2009-03-23
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3540928
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:3836768
Age: postnatal day 50
Specimen Label: 2E
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:3836762
Assay Type: RNA in situ
Annotation Date: 2009-03-23
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1672823
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:3836768
Age: embryonic day 15.0
Specimen Label: 2A
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:3836762
Assay Type: RNA in situ
Annotation Date: 2009-03-23
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1666823
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:3836768
Age: embryonic day 15.0
Specimen Label: 2A
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:3836762
Assay Type: RNA in situ
Annotation Date: 2009-03-23
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1684623
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:3836768
Age: embryonic day 15.0
Specimen Label: 2A
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:3836762
Assay Type: RNA in situ
Annotation Date: 2009-03-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3521628
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:3836768
Age: postnatal day 5
Note: Expression was detected in both external and internal granule cell layers. Staining was more evident in the internal granule cell layer.
Specimen Label: 2D
Detected: true
Specimen Num: 4
GXD Expression  
Probe: MGI:3836762
Assay Type: RNA in situ
Annotation Date: 2009-03-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1646923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:3836768
Age: embryonic day 15.0
Note: Expression was detected throughout the neuroaxis with a rostrocaudal increasing gradient.
Specimen Label: 2A
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:3836762
Assay Type: RNA in situ
Annotation Date: 2009-03-23
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1754723
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:3836768
Age: embryonic day 15.0
Specimen Label: 2B
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:3836762
Assay Type: RNA in situ
Annotation Date: 2009-03-23
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1679727
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:3836768
Age: postnatal day 0
Specimen Label: 2C
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:3836762
Assay Type: RNA in situ
Annotation Date: 2009-03-23
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3280928
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:3836768
Age: postnatal day 50
Note: Expression was weak in the olfactory neuronal layers.
Specimen Label: 2E
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:3836762
Assay Type: RNA in situ
Annotation Date: 2009-03-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3527628
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:3836768
Age: postnatal day 50
Specimen Label: 2E
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:3836762
Assay Type: RNA in situ
Annotation Date: 2009-03-23
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1822127
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:3836768
Age: postnatal day 0
Specimen Label: 2C
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:3836762
Assay Type: RNA in situ
Annotation Date: 2009-03-23
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1757723
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:3836768
Age: embryonic day 15.0
Specimen Label: 2A
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:3836762
Assay Type: RNA in situ
Annotation Date: 2009-03-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3521728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:3836768
Age: postnatal day 50
Specimen Label: 2E
Detected: true
Specimen Num: 5
Publication
First Author: Taha E
Year: 2020
Journal: Curr Biol
Title: eEF2/eEF2K Pathway in the Mature Dentate Gyrus Determines Neurogenesis Level and Cognition.
Volume: 30
Issue: 18
Pages: 3507-3521.e7
Publication
First Author: Sakagami H
Year: 2002
Journal: Neurosci Lett
Title: Transient up-regulation of elongation factor-2 kinase (Ca2+/calmodulin-dependent protein kinase III) messenger RNA in developing mouse brain.
Volume: 330
Issue: 1
Pages: 41-4
Publication
First Author: Crawley SW
Year: 2008
Journal: Biochim Biophys Acta
Title: Determinants for substrate phosphorylation by Dictyostelium myosin II heavy chain kinases A and B and eukaryotic elongation factor-2 kinase.
Volume: 1784
Issue: 6
Pages: 908-15
Publication
First Author: Im HI
Year: 2009
Journal: PLoS One
Title: Post-training dephosphorylation of eEF-2 promotes protein synthesis for memory consolidation.
Volume: 4
Issue: 10
Pages: e7424
Publication      
First Author: Knight JRP
Year: 2022
Journal: J Invest Dermatol
Title: Eukaryotic Elongation Factor 2 Kinase Activity Is Required for the Phenotypes of the Rpl24Bst Mouse.
Publication
First Author: Ryazanov AG
Year: 1999
Journal: Curr Biol
Title: Alpha-kinases: a new class of protein kinases with a novel catalytic domain.
Volume: 9
Issue: 2
Pages: R43-5
Publication
First Author: Nosyreva E
Year: 2013
Journal: J Neurosci
Title: Acute suppression of spontaneous neurotransmission drives synaptic potentiation.
Volume: 33
Issue: 16
Pages: 6990-7002
Publication
First Author: Shen Q
Year: 2009
Journal: Parkinsonism Relat Disord
Title: Expression QTL and regulatory network analysis of microtubule-associated protein tau gene.
Volume: 15
Issue: 7
Pages: 525-31
Publication
First Author: Ko MS
Year: 2000
Journal: Development
Title: Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development.
Volume: 127
Issue: 8
Pages: 1737-49
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2023
Title: TreeGrafter-generated GO annotations
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations for FANTOM2 data
Publication      
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
Publication        
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
Publication        
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara