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Search results 1 to 100 out of 2649 for Egfr

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Hits by Pathway

Hits by Strain

Hits by Category

Type Details Score
Gene
1956 | EGFR
Type: gene
Organism: human
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Gene
463415 | EGFR
Type: gene
Organism: chimpanzee
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Gene
407217 | EGFR
Type: gene
Organism: cattle
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Gene
396494 | EGFR
Type: gene
Organism: chicken
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Gene
613027 | EGFR
Type: gene
Organism: macaque, rhesus
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Gene
100492965 | egfr
Type: gene
Organism: frog, western clawed
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Gene
key_80052 | EGFR
Type: gene
Organism: cat, domestic
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Gene
24329 | Egfr
Type: gene
Organism: rat
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Gene
404306 | EGFR
Type: gene
Organism: dog, domestic
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Protein Coding Gene
MGI:95294 | Egfr
Type: protein_coding_gene
Organism: mouse, laboratory
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Gene
116435281 | EGILA
Type: gene
Organism: human
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Gene
100507500 | EGFR-AS1
Type: gene
Organism: human
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Gene
102725541 | ELDR
Type: gene
Organism: human
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Gene
2059 | EPS8
Type: gene
Organism: human
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GXD Expression
GXD Expression
 
Probe: MGI:5522883
Assay Type: Immunohistochemistry
Annotation Date: 2013-12-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1782923
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5523002
Age: embryonic day 15.5
Note: Expression was not substantially affected in the mutant eyelid.
Specimen Label: 7B EGFR Gpr48-/-
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:5522883
Assay Type: Immunohistochemistry
Annotation Date: 2013-12-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1782923
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5523002
Age: embryonic day 15.5
Specimen Label: 7B EGFR Gpr48+/+
Detected: true
Specimen Num: 1
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Publication
26120493 | J:250066
 
First Author: Zhang X
Year: 2014
Journal: Bone Res
Title: Reduced EGFR signaling enhances cartilage destruction in a mouse osteoarthritis model.
Volume: 2
Pages: 14015
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Publication
19759520 | J:154637
First Author: Regales L
Year: 2009
Journal: J Clin Invest
Title: Dual targeting of EGFR can overcome a major drug resistance mutation in mouse models of EGFR mutant lung cancer.
Volume: 119
Issue: 10
Pages: 3000-10
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Publication
23799367 | J:206889
First Author: Sigismund S
Year: 2013
Journal: EMBO J
Title: Threshold-controlled ubiquitination of the EGFR directs receptor fate.
Volume: 32
Issue: 15
Pages: 2140-57
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Publication
18500331 | -
First Author: Klein DE
Year: 2008
Journal: Nature
Title: Structural basis for EGFR ligand sequestration by Argos.
Volume: 453
Issue: 7199
Pages: 1271-5
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GXD Expression
GXD Expression
     
Probe: MGI:6171813
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689419
Stage: TS19
Assay Id: MGI:6190190
Age: embryonic day 11.5
Specimen Label: Table S2 - E11.5 - Egfr
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:6171813
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689421
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:6190190
Age: embryonic day 13.5
Specimen Label: Table S2 - E13.5 - Egfr
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:6171813
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689424
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:6190190
Age: embryonic day 15.5
Specimen Label: Table S2 - E15.5 - Egfr
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:6171813
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689426
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:6190190
Age: embryonic day 18.5
Specimen Label: Table S2 - E18.5 - Egfr
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:6171813
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6190190
Age: postnatal day 4
Specimen Label: Table S2 - P4 - Egfr
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
   
Probe: MGI:6171813
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6190190
Age: postnatal day 14
Specimen Label: Table S2 - P14 - Egfr
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
   
Probe: MGI:6171813
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6190190
Age: postnatal day 28
Specimen Label: Table S2 - P28 - Egfr
Detected: true
Specimen Num: 7
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Publication
20732323 | J:164387
First Author: Wang Z
Year: 2010
Journal: FEBS Lett
Title: GPR48-Induced keratinocyte proliferation occurs through HB-EGF mediated EGFR transactivation.
Volume: 584
Issue: 18
Pages: 4057-62
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Publication
19931240 | J:223286
First Author: Schneider MR
Year: 2010
Journal: Exp Mol Pathol
Title: EGFR ligands exert diverging effects on male reproductive organs.
Volume: 88
Issue: 1
Pages: 216-8
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Publication
17618276 | J:124200
First Author: Aguirre A
Year: 2007
Journal: Nat Neurosci
Title: A functional role for EGFR signaling in myelination and remyelination.
Volume: 10
Issue: 8
Pages: 990-1002
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Publication
15482488 | J:120140
First Author: Repertinger SK
Year: 2004
Journal: J Invest Dermatol
Title: EGFR enhances early healing after cutaneous incisional wounding.
Volume: 123
Issue: 5
Pages: 982-9
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Publication
24695557 | J:215030
First Author: Hakonen E
Year: 2014
Journal: PLoS One
Title: EGFR signaling promotes β-cell proliferation and survivin expression during pregnancy.
Volume: 9
Issue: 4
Pages: e93651
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Publication
27346347 | J:238519
First Author: Forloni M
Year: 2016
Journal: Cell Rep
Title: Oncogenic EGFR Represses the TET1 DNA Demethylase to Induce Silencing of Tumor Suppressors in Cancer Cells.
Volume: 16
Issue: 2
Pages: 457-71
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Publication
17121848 | J:118531
First Author: Alwan HA
Year: 2007
Journal: J Biol Chem
Title: UBPY-mediated epidermal growth factor receptor (EGFR) de-ubiquitination promotes EGFR degradation.
Volume: 282
Issue: 3
Pages: 1658-69
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Publication
27482886 | J:237254
First Author: Hardbower DM
Year: 2016
Journal: J Clin Invest
Title: EGFR regulates macrophage activation and function in bacterial infection.
Volume: 126
Issue: 9
Pages: 3296-312
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Publication
28783046 | J:247650
First Author: Martin LJ
Year: 2017
Journal: J Clin Invest
Title: Epiregulin and EGFR interactions are involved in pain processing.
Volume: 127
Issue: 9
Pages: 3353-3366
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Publication
19049329 | J:168674
First Author: Schneider MR
Year: 2009
Journal: J Bone Miner Res
Title: High cortical bone mass phenotype in betacellulin transgenic mice is EGFR dependent.
Volume: 24
Issue: 3
Pages: 455-67
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Publication
27330189 | J:259991
First Author: Cataisson C
Year: 2016
Journal: Sci Signal
Title: MET signaling in keratinocytes activates EGFR and initiates squamous carcinogenesis.
Volume: 9
Issue: 433
Pages: ra62
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Publication
23211830 | J:214578
First Author: Hassemer EL
Year: 2013
Journal: Invest Ophthalmol Vis Sci
Title: ADAM17 transactivates EGFR signaling during embryonic eyelid closure.
Volume: 54
Issue: 1
Pages: 132-40
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Publication
23966300 | J:213462
First Author: Lichtenberger BM
Year: 2013
Journal: Sci Transl Med
Title: Epidermal EGFR controls cutaneous host defense and prevents inflammation.
Volume: 5
Issue: 199
Pages: 199ra111
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Publication
36445254 | J:333622
First Author: Ko A
Year: 2023
Journal: Cancer Discov
Title: LZTR1 Mutation Mediates Oncogenesis through Stabilization of EGFR and AXL.
Volume: 13
Issue: 3
Pages: 702-723
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Publication
18830272 | J:145069
First Author: Maklad A
Year: 2009
Journal: J Invest Dermatol
Title: The EGFR is required for proper innervation to the skin.
Volume: 129
Issue: 3
Pages: 690-8
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Publication
24530706 | J:310892
First Author: Chaturvedi R
Year: 2014
Journal: Gastroenterology
Title: Activation of EGFR and ERBB2 by Helicobacter pylori results in survival of gastric epithelial cells with DNA damage.
Volume: 146
Issue: 7
Pages: 1739-51.e14
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Publication
27775074 | J:241262
First Author: Ambrogio C
Year: 2017
Journal: Oncogene
Title: In vivo oncogenic conflict triggered by co-existing KRAS and EGFR activating mutations in lung adenocarcinoma.
Volume: 36
Issue: 16
Pages: 2309-2318
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Publication
28494873 | J:256252
First Author: Yang YP
Year: 2017
Journal: Cell Rep
Title: A Chimeric Egfr Protein Reporter Mouse Reveals Egfr Localization and Trafficking In Vivo.
Volume: 19
Issue: 6
Pages: 1257-1267
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Publication
24493201 | J:210180
First Author: Hakonen E
Year: 2014
Journal: Diabetologia
Title: In vivo activation of the PI3K-Akt pathway in mouse beta cells by the EGFR mutation L858R protects against diabetes.
Volume: 57
Issue: 5
Pages: 970-9
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Publication
27911782 | J:239084
First Author: Jia H
Year: 2016
Journal: Proc Natl Acad Sci U S A
Title: EGFR signaling is critical for maintaining the superficial layer of articular cartilage and preventing osteoarthritis initiation.
Volume: 113
Issue: 50
Pages: 14360-14365
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Publication
26492920 | J:252064
First Author: Scheving LA
Year: 2015
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Loss of hepatocyte ERBB3 but not EGFR impairs hepatocarcinogenesis.
Volume: 309
Issue: 12
Pages: G942-54
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Publication
25912735 | J:230528
First Author: Yang CH
Year: 2015
Journal: Biochim Biophys Acta
Title: EGFR over-expression in non-small cell lung cancers harboring EGFR mutations is associated with marked down-regulation of CD82.
Volume: 1852
Issue: 7
Pages: 1540-9
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Publication
16467848 | J:106026
First Author: Wagner B
Year: 2006
Journal: EMBO J
Title: Neuronal survival depends on EGFR signaling in cortical but not midbrain astrocytes.
Volume: 25
Issue: 4
Pages: 752-62
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Publication
20403327 | J:164741
First Author: Cheng X
Year: 2010
Journal: Cell
Title: TRP channel regulates EGFR signaling in hair morphogenesis and skin barrier formation.
Volume: 141
Issue: 2
Pages: 331-43
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Publication
31931029 | J:285655
 
First Author: Yu JJ
Year: 2020
Journal: Cancer Lett
Title: Disruption of the EGFR-SQSTM1 interaction by a stapled peptide suppresses lung cancer via activating autophagy and inhibiting EGFR signaling.
Volume: 474
Pages: 23-35
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Publication
28656962 | J:250225
 
First Author: Laviolette LA
Year: 2017
Journal: Nat Commun
Title: Negative regulation of EGFR signalling by the human folliculin tumour suppressor protein.
Volume: 8
Pages: 15866
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Publication
23684791 | J:199003
First Author: Tang J
Year: 2013
Journal: Am J Pathol
Title: Sustained activation of EGFR triggers renal fibrogenesis after acute kidney injury.
Volume: 183
Issue: 1
Pages: 160-72
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Publication
12791272 | J:84512
First Author: Zenz R
Year: 2003
Journal: Dev Cell
Title: c-Jun regulates eyelid closure and skin tumor development through EGFR signaling.
Volume: 4
Issue: 6
Pages: 879-89
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Publication
25744720 | J:220697
First Author: Zhong S
Year: 2015
Journal: Cancer Res
Title: Lung Tumor Suppressor GPRC5A Binds EGFR and Restrains Its Effector Signaling.
Volume: 75
Issue: 9
Pages: 1801-14
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Publication
21136383 | J:170365
First Author: Sanchis A
Year: 2010
Journal: Int J Dev Biol
Title: Glucocorticoid receptor antagonizes EGFR function to regulate eyelid development.
Volume: 54
Issue: 10
Pages: 1473-80
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Publication
30361264 | J:295148
 
First Author: Linder M
Year: 2018
Journal: EMBO Mol Med
Title: EGFR is required for FOS-dependent bone tumor development via RSK2/CREB signaling.
Volume: 10
Issue: 11
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Publication
21857648 | J:177192
First Author: Inoue A
Year: 2011
Journal: EMBO J
Title: LPA-producing enzyme PA-PLA₁α regulates hair follicle development by modulating EGFR signalling.
Volume: 30
Issue: 20
Pages: 4248-60
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Publication
33561544 | J:305673
 
First Author: Kim MJ
Year: 2021
Journal: Mol Metab
Title: Distinct roles of UVRAG and EGFR signaling in skeletal muscle homeostasis.
Volume: 47
Pages: 101185
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Publication
29445126 | J:268761
First Author: Linder M
Year: 2018
Journal: Cell Death Differ
Title: EGFR controls bone development by negatively regulating mTOR-signaling during osteoblast differentiation.
Volume: 25
Issue: 6
Pages: 1094-1106
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Publication
20208556 | J:168265
First Author: Rocher-Ros V
Year: 2010
Journal: Oncogene
Title: Presenilin modulates EGFR signaling and cell transformation by regulating the ubiquitin ligase Fbw7.
Volume: 29
Issue: 20
Pages: 2950-61
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Publication
10700187 | J:60750
First Author: Chen B
Year: 2000
Journal: Nat Genet
Title: Mice mutant for Egfr and Shp2 have defective cardiac semilunar valvulogenesis.
Volume: 24
Issue: 3
Pages: 296-9
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Publication
20844536 | J:164664
First Author: Aguirre A
Year: 2010
Journal: Nature
Title: Notch and EGFR pathway interaction regulates neural stem cell number and self-renewal.
Volume: 467
Issue: 7313
Pages: 323-7
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Publication
28472347 | J:245788
First Author: Xu X
Year: 2017
Journal: Carcinogenesis
Title: Muc1 knockout potentiates murine lung carcinogenesis involving an epiregulin-mediated EGFR activation feedback loop.
Volume: 38
Issue: 6
Pages: 604-614
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Publication
31131063 | J:295519
First Author: Xu L
Year: 2019
Journal: Theranostics
Title: EGFR drives the progression of AKI to CKD through HIPK2 overexpression.
Volume: 9
Issue: 9
Pages: 2712-2726
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Publication
25173978 | J:266808
First Author: Lanaya H
Year: 2014
Journal: Nat Cell Biol
Title: EGFR has a tumour-promoting role in liver macrophages during hepatocellular carcinoma formation.
Volume: 16
Issue: 10
Pages: 972-7
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Publication
28418591 | J:271833
First Author: Allan CM
Year: 2017
Journal: Exp Dermatol
Title: A hypomorphic Egfr allele does not ameliorate the palmoplantar keratoderma caused by SLURP1 deficiency.
Volume: 26
Issue: 11
Pages: 1134-1136
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Publication
25327963 | J:218288
First Author: Falcone C
Year: 2015
Journal: Glia
Title: Emx2 expression levels in NSCs modulate astrogenesis rates by regulating EgfR and Fgf9.
Volume: 63
Issue: 3
Pages: 412-22
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Publication
30975481 | J:274213
First Author: Blasco MT
Year: 2019
Journal: Cancer Cell
Title: Complete Regression of Advanced Pancreatic Ductal Adenocarcinomas upon Combined Inhibition of EGFR and C-RAF.
Volume: 35
Issue: 4
Pages: 573-587.e6
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Publication
27475257 | J:253907
First Author: Mendoza Bertelli A
Year: 2016
Journal: Biochim Biophys Acta
Title: Staphylococcus aureus protein A enhances osteoclastogenesis via TNFR1 and EGFR signaling.
Volume: 1862
Issue: 10
Pages: 1975-83
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Publication
15592458 | J:196638
First Author: Mattila E
Year: 2005
Journal: Nat Cell Biol
Title: Negative regulation of EGFR signalling through integrin-alpha1beta1-mediated activation of protein tyrosine phosphatase TCPTP.
Volume: 7
Issue: 1
Pages: 78-85
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Publication
31562318 | J:279471
First Author: Belle NM
Year: 2019
Journal: Nat Commun
Title: TFF3 interacts with LINGO2 to regulate EGFR activation for protection against colitis and gastrointestinal helminths.
Volume: 10
Issue: 1
Pages: 4408
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Publication
22306420 | J:181912
First Author: Dahlhoff M
Year: 2012
Journal: Am J Pathol
Title: Negative feedback mechanisms surpass the effect of intrinsic EGFR activation during skin chemical carcinogenesis.
Volume: 180
Issue: 4
Pages: 1378-85
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Publication
18564139 | J:139882
First Author: Ohashi K
Year: 2008
Journal: Cancer Sci
Title: Induction of lung adenocarcinoma in transgenic mice expressing activated EGFR driven by the SP-C promoter.
Volume: 99
Issue: 9
Pages: 1747-53
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Publication
27549668 | J:310611
First Author: Osawa M
Year: 2016
Journal: Acta Med Okayama
Title: Effect of Vandetanib on Lung Tumorigenesis in Transgenic Mice Carrying an Activating Egfr Gene Mutation.
Volume: 70
Issue: 4
Pages: 243-53
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Publication
27012600 | J:250758
First Author: Schreier B
Year: 2016
Journal: Biochim Biophys Acta
Title: Substance-specific importance of EGFR for vascular smooth muscle cells motility in primary culture.
Volume: 1863
Issue: 7 Pt A
Pages: 1519-33
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Publication
31426531 | J:290336
 
First Author: Yamaoka T
Year: 2019
Journal: Int J Mol Sci
Title: Blockade of EGFR Activation Promotes TNF-Induced Lung Epithelial Cell Apoptosis and Pulmonary Injury.
Volume: 20
Issue: 16
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Publication
18313710 | J:135632
First Author: Barrick CJ
Year: 2008
Journal: Toxicol Appl Pharmacol
Title: Chronic pharmacologic inhibition of EGFR leads to cardiac dysfunction in C57BL/6J mice.
Volume: 228
Issue: 3
Pages: 315-25
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Publication
29191921 | J:283406
First Author: Zeboudj L
Year: 2018
Journal: Arterioscler Thromb Vasc Biol
Title: Selective EGFR (Epidermal Growth Factor Receptor) Deletion in Myeloid Cells Limits Atherosclerosis-Brief Report.
Volume: 38
Issue: 1
Pages: 114-119
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Publication
20639532 | J:173825
First Author: Peng SC
Year: 2010
Journal: Nucleic Acids Res
Title: A novel role of CPEB3 in regulating EGFR gene transcription via association with Stat5b in neurons.
Volume: 38
Issue: 21
Pages: 7446-57
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Publication
27077118 | J:260433
 
First Author: Shimoda M
Year: 2016
Journal: EBioMedicine
Title: Epithelial Cell-Derived a Disintegrin and Metalloproteinase-17 Confers Resistance to Colonic Inflammation Through EGFR Activation.
Volume: 5
Pages: 114-24
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Publication
16079154 | J:278817
First Author: Sternlicht MD
Year: 2005
Journal: Development
Title: Mammary ductal morphogenesis requires paracrine activation of stromal EGFR via ADAM17-dependent shedding of epithelial amphiregulin.
Volume: 132
Issue: 17
Pages: 3923-33
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Publication
20141840 | J:156995
First Author: Lichtenberger BM
Year: 2010
Journal: Cell
Title: Autocrine VEGF signaling synergizes with EGFR in tumor cells to promote epithelial cancer development.
Volume: 140
Issue: 2
Pages: 268-79
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Publication
19890352 | J:159552
First Author: Mascia F
Year: 2010
Journal: J Invest Dermatol
Title: EGFR regulates the expression of keratinocyte-derived granulocyte/macrophage colony-stimulating factor in vitro and in vivo.
Volume: 130
Issue: 3
Pages: 682-93
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Publication
32150794 | J:297736
First Author: Kim MJ
Year: 2020
Journal: Mol Cells
Title: Reduced EGFR Level in eIF2α PhosphorylationDeficient Hepatocytes Is Responsible for Susceptibility to Oxidative Stress.
Volume: 43
Issue: 3
Pages: 264-275
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Publication
18487371 | J:141686
First Author: Jin C
Year: 2008
Journal: Invest Ophthalmol Vis Sci
Title: GPR48 regulates epithelial cell proliferation and migration by activating EGFR during eyelid development.
Volume: 49
Issue: 10
Pages: 4245-53
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Publication
22733137 | J:198024
First Author: Li A
Year: 2013
Journal: Oncogene
Title: TIP30 loss enhances cytoplasmic and nuclear EGFR signaling and promotes lung adenocarcinogenesis in mice.
Volume: 32
Issue: 18
Pages: 2273-81, 2281e.1-12
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Publication
28933590 | J:310499
First Author: Muniz-Feliciano L
Year: 2017
Journal: Autophagy
Title: RUBCN/rubicon and EGFR regulate lysosomal degradative processes in the retinal pigment epithelium (RPE) of the eye.
Volume: 13
Issue: 12
Pages: 2072-2085
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Publication
33762435 | J:304348
 
First Author: Li K
Year: 2021
Journal: Sci Transl Med
Title: Faciogenital Dysplasia 5 supports cancer stem cell traits in basal-like breast cancer by enhancing EGFR stability.
Volume: 13
Issue: 586
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