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Search results 1 to 100 out of 285 for Egln1

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0.042s
Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: chimpanzee
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: rat
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Publication    
First Author: Taylor MS
Year: 2001
Journal: GenBank Submission
Title: Mus musculus partial mRNA for EGLN1 protein
Pages: AJ310546
Publication
First Author: Olenchock BA
Year: 2016
Journal: Cell
Title: EGLN1 Inhibition and Rerouting of α-Ketoglutarate Suffice for Remote Ischemic Protection.
Volume: 164
Issue: 5
Pages: 884-95
Protein
Organism: Mus musculus/domesticus
Length: 235  
Fragment?: true
Publication
First Author: Ozolins TR
Year: 2009
Journal: Biochem Biophys Res Commun
Title: Defects in embryonic development of EGLN1/PHD2 knockdown transgenic mice are associated with induction of Igfbp in the placenta.
Volume: 390
Issue: 3
Pages: 372-6
Publication
First Author: Zhang T
Year: 2023
Journal: Nat Cell Biol
Title: Prolonged hypoxia alleviates prolyl hydroxylation-mediated suppression of RIPK1 to promote necroptosis and inflammation.
Volume: 25
Issue: 7
Pages: 950-962
Publication
First Author: Taylor MS
Year: 2001
Journal: Gene
Title: Characterization and comparative analysis of the EGLN gene family.
Volume: 275
Issue: 1
Pages: 125-32
Publication
First Author: Dai Z
Year: 2016
Journal: Circulation
Title: Prolyl-4 Hydroxylase 2 (PHD2) Deficiency in Endothelial Cells and Hematopoietic Cells Induces Obliterative Vascular Remodeling and Severe Pulmonary Arterial Hypertension in Mice and Humans Through Hypoxia-Inducible Factor-2α.
Volume: 133
Issue: 24
Pages: 2447-58
Publication
First Author: Gomes AP
Year: 2013
Journal: Cell
Title: Declining NAD(+) induces a pseudohypoxic state disrupting nuclear-mitochondrial communication during aging.
Volume: 155
Issue: 7
Pages: 1624-38
Publication
First Author: Minamishima YA
Year: 2008
Journal: Blood
Title: Somatic inactivation of the PHD2 prolyl hydroxylase causes polycythemia and congestive heart failure.
Volume: 111
Issue: 6
Pages: 3236-44
Publication
First Author: Arsenault PR
Year: 2016
Journal: Mol Cell Biol
Title: The Zinc Finger of Prolyl Hydroxylase Domain Protein 2 Is Essential for Efficient Hydroxylation of Hypoxia-Inducible Factor α.
Volume: 36
Issue: 18
Pages: 2328-43
Publication
First Author: Tang H
Year: 2018
Journal: Am J Physiol Lung Cell Mol Physiol
Title: Endothelial HIF-2α contributes to severe pulmonary hypertension due to endothelial-to-mesenchymal transition.
Volume: 314
Issue: 2
Pages: L256-L275
Publication
First Author: Arsenault PR
Year: 2013
Journal: J Biol Chem
Title: A knock-in mouse model of human PHD2 gene-associated erythrocytosis establishes a haploinsufficiency mechanism.
Volume: 288
Issue: 47
Pages: 33571-84
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Wu S
Year: 2008
Journal: Mol Ther
Title: Enhancement of angiogenesis through stabilization of hypoxia-inducible factor-1 by silencing prolyl hydroxylase domain-2 gene.
Volume: 16
Issue: 7
Pages: 1227-34
Publication
First Author: Duan LJ
Year: 2011
Journal: Am J Pathol
Title: Prolyl hydroxylase domain protein 2 (PHD2) mediates oxygen-induced retinopathy in neonatal mice.
Volume: 178
Issue: 4
Pages: 1881-90
Publication
First Author: Kuchnio A
Year: 2015
Journal: Cell Rep
Title: The Cancer Cell Oxygen Sensor PHD2 Promotes Metastasis via Activation of Cancer-Associated Fibroblasts.
Volume: 12
Issue: 6
Pages: 992-1005
Publication
First Author: Fan Q
Year: 2019
Journal: Am J Pathol
Title: Prolyl Hydroxylase Domain-2 Protein Regulates Lipopolysaccharide-Induced Vascular Inflammation.
Volume: 189
Issue: 1
Pages: 200-213
Publication
First Author: Wang S
Year: 2016
Journal: Oncotarget
Title: Loss of prolyl hydroxylase domain protein 2 in vascular endothelium increases pericyte coverage and promotes pulmonary arterial remodeling.
Volume: 7
Issue: 37
Pages: 58848-58861
Publication
First Author: Wang S
Year: 2017
Journal: J Cell Mol Med
Title: Ablation of endothelial prolyl hydroxylase domain protein-2 promotes renal vascular remodelling and fibrosis in mice.
Volume: 21
Issue: 9
Pages: 1967-1978
Publication
First Author: Zhou LY
Year: 2018
Journal: Cell Physiol Biochem
Title: Regulatory Role of Endothelial PHD2 in the Hepatic Steatosis.
Volume: 48
Issue: 3
Pages: 1003-1011
Publication
First Author: Thienpont B
Year: 2016
Journal: Nature
Title: Tumour hypoxia causes DNA hypermethylation by reducing TET activity.
Volume: 537
Issue: 7618
Pages: 63-68
Publication
First Author: Zeng H
Year: 2014
Journal: PLoS One
Title: Conditional knockout of prolyl hydroxylase domain protein 2 attenuates high fat-diet-induced cardiac dysfunction in mice.
Volume: 9
Issue: 12
Pages: e115974
Publication  
First Author: Cheng S
Year: 2016
Journal: Sci Rep
Title: Prolyl Hydroxylase Domain-Containing Protein 2 (Phd2) Regulates Chondrocyte Differentiation and Secondary Ossification in Mice.
Volume: 6
Pages: 35748
Publication
First Author: Suhara T
Year: 2015
Journal: Proc Natl Acad Sci U S A
Title: Inhibition of the oxygen sensor PHD2 in the liver improves survival in lactic acidosis by activating the Cori cycle.
Volume: 112
Issue: 37
Pages: 11642-7
Publication  
First Author: Duan LJ
Year: 2019
Journal: Development
Title: Developmental vascular pruning in neonatal mouse retinas is programmed by the astrocytic oxygen-sensing mechanism.
Volume: 146
Issue: 8
Publication
First Author: Cheng S
Year: 2016
Journal: Endocrinology
Title: Conditional Deletion of Prolyl Hydroxylase Domain-Containing Protein 2 (Phd2) Gene Reveals Its Essential Role in Chondrocyte Function and Endochondral Bone Formation.
Volume: 157
Issue: 1
Pages: 127-40
Publication
First Author: Matsuura H
Year: 2013
Journal: Circulation
Title: Prolyl hydroxylase domain protein 2 plays a critical role in diet-induced obesity and glucose intolerance.
Volume: 127
Issue: 21
Pages: 2078-87
Publication
First Author: Xie Y
Year: 2018
Journal: Acta Biochim Biophys Sin (Shanghai)
Title: Prolyl hydroxylase 2 is dispensable for homeostasis of intestinal epithelium in mice.
Volume: 50
Issue: 6
Pages: 540-546
Publication
First Author: Zimmermann AS
Year: 2014
Journal: PLoS One
Title: Epidermal or dermal specific knockout of PHD-2 enhances wound healing and minimizes ischemic injury.
Volume: 9
Issue: 4
Pages: e93373
Publication
First Author: Mazzone M
Year: 2009
Journal: Cell
Title: Heterozygous deficiency of PHD2 restores tumor oxygenation and inhibits metastasis via endothelial normalization.
Volume: 136
Issue: 5
Pages: 839-851
Publication
First Author: Manresa MC
Year: 2016
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Hydroxylase inhibition regulates inflammation-induced intestinal fibrosis through the suppression of ERK-mediated TGF-β1 signaling. [corrected].
Volume: 311
Issue: 6
Pages: G1076-G1090
Publication
First Author: Rahtu-Korpela L
Year: 2014
Journal: Diabetes
Title: HIF prolyl 4-hydroxylase-2 inhibition improves glucose and lipid metabolism and protects against obesity and metabolic dysfunction.
Volume: 63
Issue: 10
Pages: 3324-33
Publication
First Author: Settelmeier S
Year: 2020
Journal: PLoS One
Title: Prolyl hydroxylase domain 2 reduction enhances skeletal muscle tissue regeneration after soft tissue trauma in mice.
Volume: 15
Issue: 5
Pages: e0233261
Publication
First Author: Kerkelä R
Year: 2013
Journal: Mol Cell Biol
Title: Activation of hypoxia response in endothelial cells contributes to ischemic cardioprotection.
Volume: 33
Issue: 16
Pages: 3321-9
Publication  
First Author: Röning T
Year: 2022
Journal: J Mol Cell Cardiol
Title: Activation of the hypoxia response pathway protects against age-induced cardiac hypertrophy.
Volume: 164
Pages: 148-155
Publication
First Author: Laitakari A
Year: 2020
Journal: FASEB J
Title: Systemic long-term inactivation of hypoxia-inducible factor prolyl 4-hydroxylase 2 ameliorates aging-induced changes in mice without affecting their life span.
Volume: 34
Issue: 4
Pages: 5590-5609
Publication
First Author: Karsikas S
Year: 2016
Journal: J Mol Med (Berl)
Title: HIF-P4H-2 deficiency protects against skeletal muscle ischemia-reperfusion injury.
Volume: 94
Issue: 3
Pages: 301-10
Publication
First Author: Dupuy D
Year: 2000
Journal: Genomics
Title: Mapping, characterization, and expression analysis of the SM-20 human homologue, c1orf12, and identification of a novel related gene, SCAND2.
Volume: 69
Issue: 3
Pages: 348-54
Publication  
First Author: Gruneberg D
Year: 2016
Journal: Exp Neurol
Title: Neuronal prolyl-4-hydroxylase 2 deficiency improves cognitive abilities in a murine model of cerebral hypoperfusion.
Volume: 286
Pages: 93-106
Publication
First Author: Yamamoto A
Year: 2019
Journal: J Clin Invest
Title: Systemic silencing of PHD2 causes reversible immune regulatory dysfunction.
Volume: 129
Issue: 9
Pages: 3640-3656
Publication  
First Author: Zhu J
Year: 2021
Journal: Front Cell Dev Biol
Title: Hypoxia-Inducible Factor 2-Alpha Mediated Gene Sets Differentiate Pulmonary Arterial Hypertension.
Volume: 9
Pages: 701247
GXD Expression    
Probe: MGI:6285767
Assay Type: Western blot
Annotation Date: 2019-04-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3284528
Stage: TS28
Assay Id: MGI:6285769
Age: postnatal
Image: S4-part 2
Specimen Label: ctrl
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:6285767
Assay Type: Western blot
Annotation Date: 2019-04-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3284528
Stage: TS28
Assay Id: MGI:6285769
Age: postnatal
Image: S4-part 2
Specimen Label: ctrl
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:6285767
Assay Type: Western blot
Annotation Date: 2019-04-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3284528
Stage: TS28
Assay Id: MGI:6285769
Age: postnatal
Image: S4-part 2
Specimen Label: ctrl
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:6285767
Assay Type: Western blot
Annotation Date: 2019-04-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3284528
Stage: TS28
Assay Id: MGI:6285769
Age: postnatal
Image: S4-part 2
Specimen Label: ctrl
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:6285767
Assay Type: Western blot
Annotation Date: 2019-04-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3284528
Stage: TS28
Assay Id: MGI:6285769
Age: postnatal
Image: S4-part 2
Specimen Label: ctrl
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:6285767
Assay Type: Western blot
Annotation Date: 2019-04-02
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3284528
Stage: TS28
Assay Id: MGI:6285769
Age: postnatal
Image: S4-part 2
Specimen Label: PHD2NKO
Detected: false
Specimen Num: 6
GXD Expression    
Probe: MGI:6285767
Assay Type: Western blot
Annotation Date: 2019-04-02
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3284528
Stage: TS28
Assay Id: MGI:6285769
Age: postnatal
Image: S4-part 2
Specimen Label: PHD2NKO
Detected: false
Specimen Num: 7
GXD Expression    
Probe: MGI:6285767
Assay Type: Western blot
Annotation Date: 2019-04-02
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3284528
Stage: TS28
Assay Id: MGI:6285769
Age: postnatal
Image: S4-part 2
Specimen Label: PHD2NKO
Detected: false
Specimen Num: 8
GXD Expression    
Probe: MGI:6285767
Assay Type: Western blot
Annotation Date: 2019-04-02
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3284528
Stage: TS28
Assay Id: MGI:6285769
Age: postnatal
Image: S4-part 2
Specimen Label: PHD2NKO
Detected: false
Specimen Num: 9
GXD Expression    
Probe: MGI:6285715
Assay Type: RT-PCR
Annotation Date: 2019-04-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754422
Stage: TS22
Assay Id: MGI:6285763
Age: embryonic day 14.5
Image: S4
Specimen Label: Phd1
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:6285767
Assay Type: Western blot
Annotation Date: 2019-04-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:6285821
Age: postnatal
Image: 4
Specimen Label: H
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:6285767
Assay Type: Western blot
Annotation Date: 2019-04-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:6285821
Age: postnatal
Image: 4
Specimen Label: H
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:6285715
Assay Type: RT-PCR
Annotation Date: 2019-04-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3284525
Stage: TS25
Assay Id: MGI:6285763
Age: embryonic day 17.0
Image: S4
Specimen Label: Phd1
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:3507276
Assay Type: RNA in situ
Annotation Date: 2004-12-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3185821
Stage: TS21
Assay Id: MGI:3508310
Age: embryonic day 13.5
Image: 1
Specimen Label: 1
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:3507276
Assay Type: RNA in situ
Annotation Date: 2004-12-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1647021
Stage: TS21
Assay Id: MGI:3508310
Age: embryonic day 13.5
Image: 1
Specimen Label: 1
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:3507276
Assay Type: RNA in situ
Annotation Date: 2004-12-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1754421
Stage: TS21
Assay Id: MGI:3508310
Age: embryonic day 13.5
Image: 1
Specimen Label: 1
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:3507276
Assay Type: RNA in situ
Annotation Date: 2004-12-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1754921
Stage: TS21
Assay Id: MGI:3508310
Age: embryonic day 13.5
Image: 1
Specimen Label: 1
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:3507276
Assay Type: RNA in situ
Annotation Date: 2004-12-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1754021
Stage: TS21
Assay Id: MGI:3508310
Age: embryonic day 13.5
Image: 1
Specimen Label: 1
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:3507276
Assay Type: RNA in situ
Annotation Date: 2004-12-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1753621
Stage: TS21
Assay Id: MGI:3508310
Age: embryonic day 13.5
Image: 1
Specimen Label: 1
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:3507276
Assay Type: RNA in situ
Annotation Date: 2004-12-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1697421
Stage: TS21
Assay Id: MGI:3508310
Age: embryonic day 13.5
Image: 1
Specimen Label: 1
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:3507276
Assay Type: RNA in situ
Annotation Date: 2004-12-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1691621
Stage: TS21
Assay Id: MGI:3508310
Age: embryonic day 13.5
Image: 1
Specimen Label: 1
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:3507276
Assay Type: RNA in situ
Annotation Date: 2004-12-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1757721
Stage: TS21
Assay Id: MGI:3508310
Age: embryonic day 13.5
Image: 1
Specimen Label: 1
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:3507276
Assay Type: RNA in situ
Annotation Date: 2004-12-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1665921
Stage: TS21
Assay Id: MGI:3508310
Age: embryonic day 13.5
Image: 1
Specimen Label: 1
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:3507276
Assay Type: RNA in situ
Annotation Date: 2004-12-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1666821
Stage: TS21
Assay Id: MGI:3508310
Age: embryonic day 13.5
Image: 1
Specimen Label: 1
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:3507276
Assay Type: RNA in situ
Annotation Date: 2004-12-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3267921
Stage: TS21
Assay Id: MGI:3508310
Age: embryonic day 13.5
Image: 1
Specimen Label: 1
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:3507276
Assay Type: RNA in situ
Annotation Date: 2004-12-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1716821
Stage: TS21
Assay Id: MGI:3508310
Age: embryonic day 13.5
Image: 1
Specimen Label: 1
Detected: false
Specimen Num: 1
GXD Expression  
Probe: MGI:3507276
Assay Type: RNA in situ
Annotation Date: 2004-12-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1619321
Stage: TS21
Assay Id: MGI:3508310
Age: embryonic day 13.5
Image: 1
Note: The tissue was inner ear and ear structures.
Specimen Label: 1
Detected: false
Specimen Num: 1
GXD Expression  
Probe: MGI:3507276
Assay Type: RNA in situ
Annotation Date: 2004-12-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1777821
Stage: TS21
Assay Id: MGI:3508310
Age: embryonic day 13.5
Image: 1
Note: The tissue was olfactory epithelium and/or bulb.
Specimen Label: 1
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:3507276
Assay Type: RNA in situ
Annotation Date: 2004-12-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3185827
Stage: TS27
Assay Id: MGI:3508310
Age: postnatal newborn
Image: 2
Specimen Label: 2
Detected: false
Specimen Num: 2
GXD Expression    
Probe: MGI:3507276
Assay Type: RNA in situ
Annotation Date: 2004-12-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1647027
Stage: TS27
Assay Id: MGI:3508310
Age: postnatal newborn
Image: 2
Specimen Label: 2
Detected: false
Specimen Num: 2
GXD Expression    
Probe: MGI:3507276
Assay Type: RNA in situ
Annotation Date: 2004-12-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1754427
Stage: TS27
Assay Id: MGI:3508310
Age: postnatal newborn
Image: 2
Specimen Label: 2
Detected: false
Specimen Num: 2
GXD Expression    
Probe: MGI:3507276
Assay Type: RNA in situ
Annotation Date: 2004-12-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1754927
Stage: TS27
Assay Id: MGI:3508310
Age: postnatal newborn
Image: 2
Specimen Label: 2
Detected: false
Specimen Num: 2