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Search results 1 to 100 out of 153 for Egln2

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Type Details Score
Gene
112398 | EGLN2
Type: gene
Organism: human
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Gene
456049 | EGLN2
Type: gene
Organism: chimpanzee
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Gene
484495 | EGLN2
Type: gene
Organism: dog, domestic
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Gene
536763 | EGLN2
Type: gene
Organism: cattle
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Gene
559569 | egln2
Type: gene
Organism: zebrafish
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Gene
703083 | EGLN2
Type: gene
Organism: macaque, rhesus
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Gene
100487735 | egln2
Type: gene
Organism: frog, western clawed
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Gene
114674212 | EGLN2
Type: gene
Organism: macaque, rhesus
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Gene
308457 | Egln2
Type: gene
Organism: rat
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Protein Coding Gene
MGI:1932287 | Egln2
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
- | J:70780
   
First Author: Taylor MS
Year: 2001
Journal: GenBank Submission
Title: Mus musculus mRNA for EGLN2 protein
Pages: AJ310547
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Publication
19878873 | J:153946
First Author: Zhang Q
Year: 2009
Journal: Cancer Cell
Title: Control of cyclin D1 and breast tumorigenesis by the EglN2 prolyl hydroxylase.
Volume: 16
Issue: 5
Pages: 413-24
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Publication
24990963 | J:212076
First Author: Zheng X
Year: 2014
Journal: Genes Dev
Title: Prolyl hydroxylation by EglN2 destabilizes FOXO3a by blocking its interaction with the USP9x deubiquitinase.
Volume: 28
Issue: 13
Pages: 1429-44
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Publication
28036276 | J:325937
First Author: Takada M
Year: 2017
Journal: Oncotarget
Title: EglN2 contributes to triple negative breast tumorigenesis by functioning as a substrate for the FBW7 tumor suppressor.
Volume: 8
Issue: 4
Pages: 6787-6795
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Publication
21083501 | J:306780
First Author: Adluri RS
Year: 2011
Journal: Antioxid Redox Signal
Title: Disruption of hypoxia-inducible transcription factor-prolyl hydroxylase domain-1 (PHD-1-/-) attenuates ex vivo myocardial ischemia/reperfusion injury through hypoxia-inducible factor-1α transcription factor and its target genes in mice.
Volume: 15
Issue: 7
Pages: 1789-97
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Publication
18176562 | J:132630
First Author: Aragonés J
Year: 2008
Journal: Nat Genet
Title: Deficiency or inhibition of oxygen sensor Phd1 induces hypoxia tolerance by reprogramming basal metabolism.
Volume: 40
Issue: 2
Pages: 170-80
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Publication
11574160 | J:72041
First Author: Taylor MS
Year: 2001
Journal: Gene
Title: Characterization and comparative analysis of the EGLN gene family.
Volume: 275
Issue: 1
Pages: 125-32
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Protein Coding Gene
MGP_CAROLIEiJ_G0029398 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0031897 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0031876 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0031806 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0031881 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0031603 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_1932287 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0032346 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0030938 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0031568 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0031720 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0031676 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0031800 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0031711 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0032377 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0030662 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0031046 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0012635 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0030496 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
23080156 | J:306480
 
First Author: Pan J
Year: 2012
Journal: Adv Exp Med Biol
Title: Hyperplasia of pulmonary neuroepithelial bodies (NEB) in lungs of prolyl hydroxylase -1(PHD-1) deficient mice.
Volume: 758
Pages: 149-55
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Publication
21873682 | J:181590
First Author: Huang H
Year: 2011
Journal: Invest Ophthalmol Vis Sci
Title: Reduced retinal neovascularization, vascular permeability, and apoptosis in ischemic retinopathy in the absence of prolyl hydroxylase-1 due to the prevention of hyperoxia-induced vascular obliteration.
Volume: 52
Issue: 10
Pages: 7565-73
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Publication
27094951 | J:301606
 
First Author: Thomas A
Year: 2016
Journal: Sci Rep
Title: Hypoxia-inducible factor prolyl hydroxylase 1 (PHD1) deficiency promotes hepatic steatosis and liver-specific insulin resistance in mice.
Volume: 6
Pages: 24618
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Publication
19818783 | J:309900
First Author: Schneider M
Year: 2010
Journal: Gastroenterology
Title: Loss or silencing of the PHD1 prolyl hydroxylase protects livers of mice against ischemia/reperfusion injury.
Volume: 138
Issue: 3
Pages: 1143-54.e1-2
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Publication
31924757 | J:283908
First Author: D'Hulst G
Year: 2020
Journal: Nat Commun
Title: PHD1 controls muscle mTORC1 in a hydroxylation-independent manner by stabilizing leucyl tRNA synthetase.
Volume: 11
Issue: 1
Pages: 174
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GXD Expression
GXD Expression
   
Probe: MGI:6285714
Assay Type: RT-PCR
Annotation Date: 2019-04-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754422
Stage: TS22
Assay Id: MGI:6285718
Age: embryonic day 14.5
Image: S4
Specimen Label: Phd1
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:6285714
Assay Type: RT-PCR
Annotation Date: 2019-04-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3284525
Stage: TS25
Assay Id: MGI:6285718
Age: embryonic day 17.0
Image: S4
Specimen Label: Phd1
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:6377699
Assay Type: RNA in situ
Annotation Date: 2019-11-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1760617
Pattern: Not Specified
Stage: TS17
Assay Id: MGI:6378176
Age: embryonic day 10.5
Image: 5A Phd1 WT
Specimen Label: 5A Phd1 WT
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:6377699
Assay Type: RNA in situ
Annotation Date: 2019-11-22
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1760617
Stage: TS17
Assay Id: MGI:6378176
Age: embryonic day 10.5
Image: 5A Phd1 Six1-/-
Specimen Label: 5A Phd1 Six1-/-
Detected: false
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:6377699
Assay Type: RNA in situ
Annotation Date: 2019-11-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3669717
Pattern: Regionally restricted
Stage: TS17
Assay Id: MGI:6378176
Age: embryonic day 10.5
Image: 5A Phd1 Six1-/-
Note: Expression in cells outside of the olfactory epithelium, corresponding to pioneer neurons.
Specimen Label: 5A Phd1 Six1-/-
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:6285708
Assay Type: RNA in situ
Annotation Date: 2019-04-02
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3284528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6285711
Age: postnatal adult
Image: S4A bottom
Specimen Label: S4A bottom
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:6285708
Assay Type: RNA in situ
Annotation Date: 2019-04-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689422
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:6285711
Age: embryonic day 14.5
Image: S4A top
Specimen Label: S4A top
Detected: true
Specimen Num: 1
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Publication
10754103 | J:61078
First Author: Tong ZB
Year: 2000
Journal: Mamm Genome
Title: Mater encodes a maternal protein in mice with a leucine-rich repeat domain homologous to porcine ribonuclease inhibitor.
Volume: 11
Issue: 4
Pages: 281-7
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Publication
32715763 | J:296776
First Author: Zhao Y
Year: 2020
Journal: Am J Physiol Renal Physiol
Title: Endothelial prolyl hydroxylase 2 is necessary for angiotensin II-mediated renal fibrosis and injury.
Volume: 319
Issue: 2
Pages: F345-F357
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Publication
27130823 | J:235380
First Author: Fitzpatrick SF
Year: 2016
Journal: Biochem Biophys Res Commun
Title: Prolyl hydroxylase-1 regulates hepatocyte apoptosis in an NF-κB-dependent manner.
Volume: 474
Issue: 3
Pages: 579-586
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Publication
37847687 | J:342470
First Author: Barnes EA
Year: 2023
Journal: Am J Physiol Lung Cell Mol Physiol
Title: Loss of prolyl hydroxylase 1 and 2 in SM22α-expressing cells prevents Hypoxia-Induced pulmonary hypertension.
Volume: 325
Issue: 6
Pages: L741-L755
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Publication
26818499 | J:229447
First Author: Rajagopalan S
Year: 2016
Journal: J Neurosci
Title: Regulation of ATP13A2 via PHD2-HIF1α Signaling Is Critical for Cellular Iron Homeostasis: Implications for Parkinson's Disease.
Volume: 36
Issue: 4
Pages: 1086-95
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Publication
27981571 | J:241898
First Author: Van Welden S
Year: 2017
Journal: J Pathol
Title: Haematopoietic prolyl hydroxylase-1 deficiency promotes M2 macrophage polarization and is both necessary and sufficient to protect against experimental colitis.
Volume: 241
Issue: 4
Pages: 547-558
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Publication
36509284 | J:332130
 
First Author: Kennel KB
Year: 2022
Journal: JCI Insight
Title: The HIF-prolyl hydroxylases have distinct and nonredundant roles in colitis-associated cancer.
Volume: 7
Issue: 22
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Publication
27561929 | J:241612
 
First Author: Chowdhury R
Year: 2016
Journal: Nat Commun
Title: Structural basis for oxygen degradation domain selectivity of the HIF prolyl hydroxylases.
Volume: 7
Pages: 12673
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Publication
20600011 | J:309903
First Author: Tambuwala MM
Year: 2010
Journal: Gastroenterology
Title: Loss of prolyl hydroxylase-1 protects against colitis through reduced epithelial cell apoptosis and increased barrier function.
Volume: 139
Issue: 6
Pages: 2093-101
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Publication
28418093 | J:243598
First Author: Hulley PA
Year: 2017
Journal: J Pathol
Title: Hypoxia-inducible factor 1-alpha does not regulate osteoclastogenesis but enhances bone resorption activity via prolyl-4-hydroxylase 2.
Volume: 242
Issue: 3
Pages: 322-333
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Publication
30248340 | J:270770
First Author: Strowitzki MJ
Year: 2018
Journal: Am J Pathol
Title: Loss of Prolyl-Hydroxylase 1 Protects against Biliary Fibrosis via Attenuated Activation of Hepatic Stellate Cells.
Volume: 188
Issue: 12
Pages: 2826-2838
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Publication
26774962 | J:232857
First Author: Quaegebeur A
Year: 2016
Journal: Cell Metab
Title: Deletion or Inhibition of the Oxygen Sensor PHD1 Protects against Ischemic Stroke via Reprogramming of Neuronal Metabolism.
Volume: 23
Issue: 2
Pages: 280-91
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Publication
23690557 | J:212783
First Author: Bishop T
Year: 2013
Journal: J Physiol
Title: Carotid body hyperplasia and enhanced ventilatory responses to hypoxia in mice with heterozygous deficiency of PHD2.
Volume: 591
Issue: 14
Pages: 3565-77
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Publication
24440788 | J:206444
First Author: Takeda K
Year: 2014
Journal: Am J Pathol
Title: Improved vascular survival and growth in the mouse model of hindlimb ischemia by a remote signaling mechanism.
Volume: 184
Issue: 3
Pages: 686-96
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Publication
24037093 | J:202021
First Author: Taniguchi CM
Year: 2013
Journal: Nat Med
Title: Cross-talk between hypoxia and insulin signaling through Phd3 regulates hepatic glucose and lipid metabolism and ameliorates diabetes.
Volume: 19
Issue: 10
Pages: 1325-30
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Publication
33819286 | J:304962
First Author: Wei GZ
Year: 2021
Journal: PLoS One
Title: Hypoxia-inducible factor prolyl hydroxylase domain (PHD) inhibition after contusive spinal cord injury does not improve locomotor recovery.
Volume: 16
Issue: 4
Pages: e0249591
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Publication
32814068 | J:301250
 
First Author: Smaila BD
Year: 2020
Journal: Exp Neurol
Title: Systemic hypoxia mimicry enhances axonal regeneration and functional recovery following peripheral nerve injury.
Volume: 334
Pages: 113436
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Publication
28716863 | J:247886
First Author: Tavernier SJ
Year: 2017
Journal: J Leukoc Biol
Title: Opposing regulation and roles for PHD3 in lung dendritic cells and alveolar macrophages.
Volume: 102
Issue: 4
Pages: 1115-1126
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Publication
24508125 | J:208042
First Author: Duan LJ
Year: 2014
Journal: Am J Pathol
Title: Hematological, hepatic, and retinal phenotypes in mice deficient for prolyl hydroxylase domain proteins in the liver.
Volume: 184
Issue: 4
Pages: 1240-50
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Publication
33298456 | J:313923
 
First Author: Byts N
Year: 2021
Journal: eNeuro
Title: Transmembrane Prolyl 4-Hydroxylase is a Novel Regulator of Calcium Signaling in Astrocytes.
Volume: 8
Issue: 1
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Publication
22786772 | J:189753
First Author: Kiss J
Year: 2012
Journal: J Immunol
Title: Loss of the oxygen sensor PHD3 enhances the innate immune response to abdominal sepsis.
Volume: 189
Issue: 4
Pages: 1955-65
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Publication
17646578 | J:133568
First Author: Takeda K
Year: 2007
Journal: Circulation
Title: Essential role for prolyl hydroxylase domain protein 2 in oxygen homeostasis of the adult vascular system.
Volume: 116
Issue: 7
Pages: 774-81
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Publication
22615432 | J:200057
First Author: Chen RL
Year: 2012
Journal: J Physiol
Title: Roles of individual prolyl-4-hydroxylase isoforms in the first 24 hours following transient focal cerebral ischaemia: insights from genetically modified mice.
Volume: 590
Issue: 16
Pages: 4079-91
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Publication
18056838 | J:132720
First Author: Takeda K
Year: 2008
Journal: Blood
Title: Regulation of adult erythropoiesis by prolyl hydroxylase domain proteins.
Volume: 111
Issue: 6
Pages: 3229-35
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Publication
27614241 | J:237383
First Author: Zhu K
Year: 2016
Journal: Gene
Title: Prolyl hydroxylase domain proteins regulate bone mass through their expression in osteoblasts.
Volume: 594
Issue: 1
Pages: 125-130
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Publication
22262480 | J:183424
First Author: Kapitsinou PP
Year: 2012
Journal: Am J Physiol Renal Physiol
Title: Preischemic targeting of HIF prolyl hydroxylation inhibits fibrosis associated with acute kidney injury.
Volume: 302
Issue: 9
Pages: F1172-9
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Publication
25446011 | J:319086
 
First Author: Rishi MT
Year: 2015
Journal: Microvasc Res
Title: Deletion of prolyl hydroxylase domain proteins (PHD1, PHD3) stabilizes hypoxia inducible factor-1 alpha, promotes neovascularization, and improves perfusion in a murine model of hind-limb ischemia.
Volume: 97
Pages: 181-8
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Publication
9799616 | J:45291
First Author: Keeney DS
Year: 1998
Journal: Genomics
Title: The novel skin-specific cytochrome P450 Cyp2b19 maps to proximal chromosome 7 in the mouse, near a cluster of Cyp2 family genes.
Volume: 53
Issue: 3
Pages: 417-9
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Publication
34718519 | J:323854
 
First Author: Hoang M
Year: 2022
Journal: Endocrinology
Title: Isoform-specific Roles of Prolyl Hydroxylases in the Regulation of Pancreatic β-Cell Function.
Volume: 163
Issue: 1
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Publication
29222481 | J:314943
First Author: Ullah K
Year: 2017
Journal: Sci Rep
Title: Hypoxia-inducible factor prolyl-4-hydroxylase-1 is a convergent point in the reciprocal negative regulation of NF-κB and p53 signaling pathways.
Volume: 7
Issue: 1
Pages: 17220
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Publication
22611156 | J:189129
First Author: Querbes W
Year: 2012
Journal: Blood
Title: Treatment of erythropoietin deficiency in mice with systemically administered siRNA.
Volume: 120
Issue: 9
Pages: 1916-22
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Publication
24145445 | J:202913
First Author: Scholz CC
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Regulation of IL-1β-induced NF-κB by hydroxylases links key hypoxic and inflammatory signaling pathways.
Volume: 110
Issue: 46
Pages: 18490-5
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Publication
18332118 | J:136034
First Author: Bishop T
Year: 2008
Journal: Mol Cell Biol
Title: Abnormal sympathoadrenal development and systemic hypotension in PHD3-/- mice.
Volume: 28
Issue: 10
Pages: 3386-400
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Publication
22014577 | J:177485
First Author: Adam J
Year: 2011
Journal: Cancer Cell
Title: Renal cyst formation in Fh1-deficient mice is independent of the Hif/Phd pathway: roles for fumarate in KEAP1 succination and Nrf2 signaling.
Volume: 20
Issue: 4
Pages: 524-37
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Publication
26054543 | J:293573
First Author: Souma T
Year: 2016
Journal: J Am Soc Nephrol
Title: Erythropoietin Synthesis in Renal Myofibroblasts Is Restored by Activation of Hypoxia Signaling.
Volume: 27
Issue: 2
Pages: 428-38
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Publication
27565342 | J:234541
First Author: Clever D
Year: 2016
Journal: Cell
Title: Oxygen Sensing by T Cells Establishes an Immunologically Tolerant Metastatic Niche.
Volume: 166
Issue: 5
Pages: 1117-1131.e14
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Publication
27088801 | J:234932
First Author: Kobayashi H
Year: 2016
Journal: J Clin Invest
Title: Distinct subpopulations of FOXD1 stroma-derived cells regulate renal erythropoietin.
Volume: 126
Issue: 5
Pages: 1926-38
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Publication
32663458 | J:296608
First Author: Yoon H
Year: 2020
Journal: Cell Metab
Title: PHD3 Loss Promotes Exercise Capacity and Fat Oxidation in Skeletal Muscle.
Volume: 32
Issue: 2
Pages: 215-228.e7
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Publication
25846796 | J:221580
First Author: Wu C
Year: 2015
Journal: Genes Dev
Title: Oxygen-sensing PHDs regulate bone homeostasis through the modulation of osteoprotegerin.
Volume: 29
Issue: 8
Pages: 817-31
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Publication
22464323 | J:186085
First Author: Rankin EB
Year: 2012
Journal: Cell
Title: The HIF signaling pathway in osteoblasts directly modulates erythropoiesis through the production of EPO.
Volume: 149
Issue: 1
Pages: 63-74
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Publication
37400498 | J:341078
First Author: Zhang T
Year: 2023
Journal: Nat Cell Biol
Title: Prolonged hypoxia alleviates prolyl hydroxylation-mediated suppression of RIPK1 to promote necroptosis and inflammation.
Volume: 25
Issue: 7
Pages: 950-962
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Publication
20651146 | J:162614
First Author: Minamishima YA
Year: 2010
Journal: Science
Title: Reactivation of hepatic EPO synthesis in mice after PHD loss.
Volume: 329
Issue: 5990
Pages: 407
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Publication
23649506 | J:244618
First Author: Zhu K
Year: 2013
Journal: J Bone Miner Res
Title: ATF4 promotes bone angiogenesis by increasing VEGF expression and release in the bone environment.
Volume: 28
Issue: 9
Pages: 1870-1884
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Publication
18347341 | J:133348
First Author: Ginouvès A
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: PHDs overactivation during chronic hypoxia "desensitizes" HIFalpha and protects cells from necrosis.
Volume: 105
Issue: 12
Pages: 4745-50
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Publication
18040029 | J:142981
First Author: Chang EI
Year: 2007
Journal: Circulation
Title: Age decreases endothelial progenitor cell recruitment through decreases in hypoxia-inducible factor 1alpha stabilization during ischemia.
Volume: 116
Issue: 24
Pages: 2818-29
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