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Search results 1 to 93 out of 93 for Ehbp1

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Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: chimpanzee
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: zebrafish
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: dog, domestic
Protein Domain
Type: Family
Description: EHBP1 is an EH domain-binding protein that links clathrin-mediated endocytosis to the actin cytoskeleton []. It contains a CH (calponin-homology) domain and interacts with EH domain protein 2 (EHD2) []. It may act as Rab effector protein playing a role in endosomal trafficking [].
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Publication
First Author: Guilherme A
Year: 2004
Journal: J Biol Chem
Title: EHD2 and the novel EH domain binding protein EHBP1 couple endocytosis to the actin cytoskeleton.
Volume: 279
Issue: 11
Pages: 10593-605
GXD Expression  
Probe: MGI:6171821
Assay Type: RNA in situ
Annotation Date: 2022-06-30
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:7294512
Age: postnatal day 56
Image: S3 EHBP1
Specimen Label: S3 EHBP1
Detected: true
Specimen Num: 1
Gene
Type: gene
Organism: human
GXD Expression  
Probe: MGI:4415979
Assay Type: RNA in situ
Annotation Date: 2022-06-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689422
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7294502
Age: embryonic day 14.5
Image: S2 EHBP1
Specimen Label: S2 EHBP1
Detected: true
Specimen Num: 1
Publication
First Author: Guilherme A
Year: 2004
Journal: J Biol Chem
Title: Role of EHD1 and EHBP1 in perinuclear sorting and insulin-regulated GLUT4 recycling in 3T3-L1 adipocytes.
Volume: 279
Issue: 38
Pages: 40062-75
Publication    
First Author: Rai A
Year: 2016
Journal: Elife
Title: bMERB domains are bivalent Rab8 family effectors evolved by gene duplication.
Volume: 5
Protein
Organism: Mus musculus/domesticus
Length: 1231  
Fragment?: false
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication    
First Author: Fuchs S
Year: 2001
Journal: GenBank Submission
Title: Mus musculus KIAA0903-like protein mRNA, complete cds
Pages: AF424697
Publication
First Author: Nakajo A
Year: 2016
Journal: J Cell Biol
Title: EHBP1L1 coordinates Rab8 and Bin1 to regulate apical-directed transport in polarized epithelial cells.
Volume: 212
Issue: 3
Pages: 297-306
Publication
First Author: Urbanek ME
Year: 2021
Journal: Sci Rep
Title: Genetic predisposition to tinnitus in the UK Biobank population.
Volume: 11
Issue: 1
Pages: 18150
Publication  
First Author: Fuchs S
Year: 2002
Journal: BMC Genet
Title: Comparative transcription map of the wobbler critical region on mouse chromosome 11 and the homologous region on human chromosome 2p13-14.
Volume: 3
Pages: 14
Publication
First Author: Bulfone A
Year: 2005
Journal: J Neurosci
Title: Telencephalic embryonic subtractive sequences: a unique collection of neurodevelopmental genes.
Volume: 25
Issue: 33
Pages: 7586-600
Publication
First Author: Araki K
Year: 1999
Journal: Cell Mol Biol (Noisy-le-grand)
Title: Exchangeable gene trap using the Cre/mutated lox system.
Volume: 45
Issue: 5
Pages: 737-50
Publication
First Author: Taniwaki T
Year: 2005
Journal: Dev Growth Differ
Title: Characterization of an exchangeable gene trap using pU-17 carrying a stop codon-beta geo cassette.
Volume: 47
Issue: 3
Pages: 163-72
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: MGC Data curation in Mouse Genome Informatics
Publication      
First Author: The Jackson Laboratory
Year: 2012
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by The Jackson Laboratory
Publication
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
Publication      
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
Publication      
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
Publication        
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
Publication
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
Publication      
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
Publication
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
Publication      
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
Publication
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
Publication        
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
Publication      
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2000
Title: Gene Ontology Annotation by electronic association of SwissProt Keywords with GO terms
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Protein Domain
Type: Family
Description: EHD (EH domain-containing protein) family is a group of endocytic recycling proteins that interact with ferlin proteins and mediate the cytoskeletal rearrangements necessary for proper membrane recycling and myoblast fusion []. Members in EHD family includes EHD1/2/3/4 []. This entry represents EHD2. It interacts with EHBP1 (EH domain-binding protein 1) and links clathrin-mediated endocytosis to the actin cytoskeleton [].
Publication
First Author: Li Z
Year: 2016
Journal: Sci Adv
Title: A novel Rab10-EHBP1-EHD2 complex essential for the autophagic engulfment of lipid droplets.
Volume: 2
Issue: 12
Pages: e1601470
Publication
First Author: Eguchi T
Year: 2018
Journal: Proc Natl Acad Sci U S A
Title: LRRK2 and its substrate Rab GTPases are sequentially targeted onto stressed lysosomes and maintain their homeostasis.
Volume: 115
Issue: 39
Pages: E9115-E9124
Publication
First Author: Posey AD Jr
Year: 2011
Journal: J Biol Chem
Title: Endocytic recycling proteins EHD1 and EHD2 interact with fer-1-like-5 (Fer1L5) and mediate myoblast fusion.
Volume: 286
Issue: 9
Pages: 7379-88
Protein
Organism: Mus musculus/domesticus
Length: 308  
Fragment?: true
Publication
First Author: Wang P
Year: 2016
Journal: PLoS Genet
Title: RAB-10 Promotes EHBP-1 Bridging of Filamentous Actin and Tubular Recycling Endosomes.
Volume: 12
Issue: 6
Pages: e1006093
Protein Domain
Type: Domain
Description: The C2 domain is one of the most prevalent eukaryotic lipid-binding domainsdeployed in diverse functional contexts. Many C2 domainsbind directly to membrane lipids and display a wide range of lipidselectivity, with preference for anionic phosphatidylserine (PS) andphosphatidylinositol-phosphates (PIPs).Despite their limited sequence similarity, all C2 domains contain at theircore a compact β-sandwich composed of two four-stranded beta sheets withhighly variable inter-strand regions that might contain one or more alpha-helices.The NT-type C2 domain shows a diverse range of domain architectures but it isnearly always found at the N-termini of proteins that contain it. Hence, ithas been named the N-terminal C2 (NT-C2) family. It is typically coupled witha coiled-coil domain, that could mediate di/oligo-merization and the DIL(Dilute) domain. It is also coupled with the Calponinhomology (CH) domain in EHBP1 proteins, Filamin/ABP280repeats and Mg2+ transporter MgtE N-terminal domain inproteins from chlorophyte algae such as Micromonas and Ostreococcus tauri.Thus, a common theme across the NT-type C2 domain proteins is the combinationto several different domains with microfilament-binding or actin-related roles(i.e. such as CH, DIL, and Filamin). Other conserved groups of the NT-type C2proteins prototyped by EEIG1, PMI1, and SYNC1 have their own distinct C-terminal conserved extensions that are restricted to these groups and mightmediate specific interactions. The primary function of the NT-type C2 domainappears to be the linking of actin/microfilament-binding adaptors to themembrane and to act as a link that tethers endosomal vesicles to thecytoskeleton in course of their intracellular trafficking [, ].
Protein
Organism: Mus musculus/domesticus
Length: 392  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 339  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 73  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 370  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 392  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 105  
Fragment?: true
Publication
First Author: Zhang D
Year: 2010
Journal: Gene
Title: Identification of novel families and classification of the C2 domain superfamily elucidate the origin and evolution of membrane targeting activities in eukaryotes.
Volume: 469
Issue: 1-2
Pages: 18-30
Protein
Organism: Mus musculus/domesticus
Length: 1716  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 762  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 744  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 877  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 774  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 1718  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 543  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 443  
Fragment?: false