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Search results 1 to 96 out of 96 for Ehbp1

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Categories

Hits by Pathway

Hits by Category

Hits by Strain

Type Details Score
Gene
23301 | EHBP1
Type: gene
Organism: human
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Gene
100492130 | ehbp1
Type: gene
Organism: frog, western clawed
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Gene
305556 | Ehbp1
Type: gene
Organism: rat
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Gene
481386 | EHBP1
Type: gene
Organism: dog, domestic
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Gene
459269 | EHBP1
Type: gene
Organism: chimpanzee
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Gene
100300164 | EHBP1
Type: gene
Organism: cattle
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Gene
421282 | EHBP1
Type: gene
Organism: chicken
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Gene
560857 | ehbp1
Type: gene
Organism: zebrafish
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Gene
693902 | EHBP1
Type: gene
Organism: macaque, rhesus
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Protein Domain
IPR029944 | EHBP1
Type: Family
Description: EHBP1 is an EH domain-binding protein that links clathrin-mediated endocytosis to the actin cytoskeleton []. It contains a CH (calponin-homology) domain and interacts with EH domain protein 2 (EHD2) []. It may act as Rab effector protein playing a role in endosomal trafficking [].
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Protein Coding Gene
MGI:2667252 | Ehbp1
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
14676205 | J:88869
First Author: Guilherme A
Year: 2004
Journal: J Biol Chem
Title: EHD2 and the novel EH domain binding protein EHBP1 couple endocytosis to the actin cytoskeleton.
Volume: 279
Issue: 11
Pages: 10593-605
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GXD Expression
GXD Expression
 
Probe: MGI:6171821
Assay Type: RNA in situ
Annotation Date: 2022-06-30
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:7294512
Age: postnatal day 56
Image: S3 EHBP1
Specimen Label: S3 EHBP1
Detected: true
Specimen Num: 1
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Gene
100132215 | EHBP1-AS1
Type: gene
Organism: human
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GXD Expression
GXD Expression
 
Probe: MGI:4415979
Assay Type: RNA in situ
Annotation Date: 2022-06-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689422
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7294502
Age: embryonic day 14.5
Image: S2 EHBP1
Specimen Label: S2 EHBP1
Detected: true
Specimen Num: 1
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Publication
15247266 | J:93351
First Author: Guilherme A
Year: 2004
Journal: J Biol Chem
Title: Role of EHD1 and EHBP1 in perinuclear sorting and insulin-regulated GLUT4 recycling in 3T3-L1 adipocytes.
Volume: 279
Issue: 38
Pages: 40062-75
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Publication
27552051 | -
   
First Author: Rai A
Year: 2016
Journal: Elife
Title: bMERB domains are bivalent Rab8 family effectors evolved by gene duplication.
Volume: 5
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Protein
Q69ZW3
Organism: Mus musculus/domesticus
Length: 1231  
Fragment?: false
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Protein Coding Gene
MGP_CAROLIEiJ_G0016127 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0018076 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0018049 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0018013 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0018017 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0017831 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_2667252 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0018469 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0017392 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0017805 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0017915 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0017907 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0017986 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0017933 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0018510 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0017173 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0017446 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0016763 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0016970 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
- | J:80343
   
First Author: Fuchs S
Year: 2001
Journal: GenBank Submission
Title: Mus musculus KIAA0903-like protein mRNA, complete cds
Pages: AF424697
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Publication
26833786 | J:236573
First Author: Nakajo A
Year: 2016
Journal: J Cell Biol
Title: EHBP1L1 coordinates Rab8 and Bin1 to regulate apical-directed transport in polarized epithelial cells.
Volume: 212
Issue: 3
Pages: 297-306
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Publication
34518561 | J:310882
First Author: Urbanek ME
Year: 2021
Journal: Sci Rep
Title: Genetic predisposition to tinnitus in the UK Biobank population.
Volume: 11
Issue: 1
Pages: 18150
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Publication
12174196 | J:83520
 
First Author: Fuchs S
Year: 2002
Journal: BMC Genet
Title: Comparative transcription map of the wobbler critical region on mouse chromosome 11 and the homologous region on human chromosome 2p13-14.
Volume: 3
Pages: 14
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Publication
16107646 | J:100324
First Author: Bulfone A
Year: 2005
Journal: J Neurosci
Title: Telencephalic embryonic subtractive sequences: a unique collection of neurodevelopmental genes.
Volume: 25
Issue: 33
Pages: 7586-600
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Publication
10512203 | J:93290
First Author: Araki K
Year: 1999
Journal: Cell Mol Biol (Noisy-le-grand)
Title: Exchangeable gene trap using the Cre/mutated lox system.
Volume: 45
Issue: 5
Pages: 737-50
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Publication
15840001 | J:110088
First Author: Taniwaki T
Year: 2005
Journal: Dev Growth Differ
Title: Characterization of an exchangeable gene trap using pU-17 carrying a stop codon-beta geo cassette.
Volume: 47
Issue: 3
Pages: 163-72
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Publication
- | J:77000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: MGC Data curation in Mouse Genome Informatics
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Publication
- | J:188991
     
First Author: The Jackson Laboratory
Year: 2012
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by The Jackson Laboratory
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Publication
12520002 | J:91812
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
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Publication
- | J:155845
     
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
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Publication
- | J:211773
     
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
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Publication
18799693 | J:142754
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
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Publication
- | J:157065
     
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
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Publication
- | J:342604
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
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Publication
38355793 | J:345621
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Protein Domain
IPR029945 | EHD2
Type: Family
Description: EHD (EH domain-containing protein) family is a group of endocytic recycling proteins that interact with ferlin proteins and mediate the cytoskeletal rearrangements necessary for proper membrane recycling and myoblast fusion []. Members in EHD family includes EHD1/2/3/4 []. This entry represents EHD2. It interacts with EHBP1 (EH domain-binding protein 1) and links clathrin-mediated endocytosis to the actin cytoskeleton [].
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Publication
28028537 | J:250136
First Author: Li Z
Year: 2016
Journal: Sci Adv
Title: A novel Rab10-EHBP1-EHD2 complex essential for the autophagic engulfment of lipid droplets.
Volume: 2
Issue: 12
Pages: e1601470
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Publication
30209220 | J:266343
First Author: Eguchi T
Year: 2018
Journal: Proc Natl Acad Sci U S A
Title: LRRK2 and its substrate Rab GTPases are sequentially targeted onto stressed lysosomes and maintain their homeostasis.
Volume: 115
Issue: 39
Pages: E9115-E9124
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Publication
21177873 | J:196263
First Author: Posey AD Jr
Year: 2011
Journal: J Biol Chem
Title: Endocytic recycling proteins EHD1 and EHD2 interact with fer-1-like-5 (Fer1L5) and mediate myoblast fusion.
Volume: 286
Issue: 9
Pages: 7379-88
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Protein
Q5SS55
Organism: Mus musculus/domesticus
Length: 308  
Fragment?: true
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Publication
27272733 | -
First Author: Wang P
Year: 2016
Journal: PLoS Genet
Title: RAB-10 Promotes EHBP-1 Bridging of Filamentous Actin and Tubular Recycling Endosomes.
Volume: 12
Issue: 6
Pages: e1006093
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Protein Domain
IPR019448 | NT-C2
Type: Domain
Description: The C2 domain is one of the most prevalent eukaryotic lipid-binding domainsdeployed in diverse functional contexts. Many C2 domainsbind directly to membrane lipids and display a wide range of lipidselectivity, with preference for anionic phosphatidylserine (PS) andphosphatidylinositol-phosphates (PIPs).Despite their limited sequence similarity, all C2 domains contain at theircore a compact β-sandwich composed of two four-stranded beta sheets withhighly variable inter-strand regions that might contain one or more alpha-helices.The NT-type C2 domain shows a diverse range of domain architectures but it isnearly always found at the N-termini of proteins that contain it. Hence, ithas been named the N-terminal C2 (NT-C2) family. It is typically coupled witha coiled-coil domain, that could mediate di/oligo-merization and the DIL(Dilute) domain. It is also coupled with the Calponinhomology (CH) domain in EHBP1 proteins, Filamin/ABP280repeats and Mg2+ transporter MgtE N-terminal domain inproteins from chlorophyte algae such as Micromonas and Ostreococcus tauri.Thus, a common theme across the NT-type C2 domain proteins is the combinationto several different domains with microfilament-binding or actin-related roles(i.e. such as CH, DIL, and Filamin). Other conserved groups of the NT-type C2proteins prototyped by EEIG1, PMI1, and SYNC1 have their own distinct C-terminal conserved extensions that are restricted to these groups and mightmediate specific interactions. The primary function of the NT-type C2 domainappears to be the linking of actin/microfilament-binding adaptors to themembrane and to act as a link that tethers endosomal vesicles to thecytoskeleton in course of their intracellular trafficking [, ].
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Protein
Q78T81
Organism: Mus musculus/domesticus
Length: 392  
Fragment?: false
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Protein
Q8BQS4
Organism: Mus musculus/domesticus
Length: 339  
Fragment?: false
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Protein
A2ASZ7
Organism: Mus musculus/domesticus
Length: 73  
Fragment?: true
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Protein
E9Q4R1
Organism: Mus musculus/domesticus
Length: 370  
Fragment?: false
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Protein
A0A158RFU0
Organism: Mus musculus/domesticus
Length: 392  
Fragment?: false
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Protein
D3Z7U7
Organism: Mus musculus/domesticus
Length: 105  
Fragment?: true
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Publication
20713135 | -
First Author: Zhang D
Year: 2010
Journal: Gene
Title: Identification of novel families and classification of the C2 domain superfamily elucidate the origin and evolution of membrane targeting activities in eukaryotes.
Volume: 469
Issue: 1-2
Pages: 18-30
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Protein
Q99MS7
Organism: Mus musculus/domesticus
Length: 1716  
Fragment?: false
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Protein
A0A494B9G7
Organism: Mus musculus/domesticus
Length: 762  
Fragment?: false
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Protein
A0A494BBL8
Organism: Mus musculus/domesticus
Length: 744  
Fragment?: true
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Protein
A0A494BA91
Organism: Mus musculus/domesticus
Length: 877  
Fragment?: false
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Protein
G5E8Y6
Organism: Mus musculus/domesticus
Length: 774  
Fragment?: false
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Protein
E9QP49
Organism: Mus musculus/domesticus
Length: 1718  
Fragment?: false
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Protein
Q8BH64
Organism: Mus musculus/domesticus
Length: 543  
Fragment?: false
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Protein
Q8R2X0
Organism: Mus musculus/domesticus
Length: 443  
Fragment?: false
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

© 2002 - 2017 Department of Genetics, University of Cambridge, Downing Street,
Cambridge CB2 3EH, United Kingdom