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Search results 1 to 100 out of 285 for Eif2ak2

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0.039s
Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: chimpanzee
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: zebrafish
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: dog, domestic
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: human
Protein
Organism: Mus musculus/domesticus
Length: 515  
Fragment?: false
Publication  
First Author: Xie M
Year: 2016
Journal: Nat Commun
Title: PKM2-dependent glycolysis promotes NLRP3 and AIM2 inflammasome activation.
Volume: 7
Pages: 13280
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Carvalho-Filho MA
Year: 2012
Journal: Endocrinology
Title: Double-stranded RNA-activated protein kinase is a key modulator of insulin sensitivity in physiological conditions and in obesity in mice.
Volume: 153
Issue: 11
Pages: 5261-74
Publication
First Author: Icely PL
Year: 1991
Journal: J Biol Chem
Title: TIK, a novel serine/threonine kinase, is recognized by antibodies directed against phosphotyrosine.
Volume: 266
Issue: 24
Pages: 16073-7
Publication
First Author: Feng GS
Year: 1992
Journal: Proc Natl Acad Sci U S A
Title: Identification of double-stranded RNA-binding domains in the interferon-induced double-stranded RNA-activated p68 kinase.
Volume: 89
Issue: 12
Pages: 5447-51
Publication
First Author: Tanaka H
Year: 1994
Journal: Proc Natl Acad Sci U S A
Title: Mechanism of interferon action: structure of the mouse PKR gene encoding the interferon-inducible RNA-dependent protein kinase.
Volume: 91
Issue: 17
Pages: 7995-9
Publication
First Author: Tanaka H
Year: 1995
Journal: Gene
Title: Sequence of the murine interferon-inducible RNA-dependent protein kinase (PKR) deduced from genomic clones.
Volume: 153
Issue: 2
Pages: 283-4
Publication
First Author: Minor RA
Year: 2010
Journal: J Interferon Cytokine Res
Title: Double-stranded RNA-activated protein kinase regulates early innate immune responses during respiratory syncytial virus infection.
Volume: 30
Issue: 4
Pages: 263-72
Publication
First Author: Liu X
Year: 2013
Journal: Blood
Title: PKR regulates proliferation, differentiation, and survival of murine hematopoietic stem/progenitor cells.
Volume: 121
Issue: 17
Pages: 3364-74
Publication
First Author: Stern E
Year: 2013
Journal: J Neurosci
Title: Blocking the eIF2α kinase (PKR) enhances positive and negative forms of cortex-dependent taste memory.
Volume: 33
Issue: 6
Pages: 2517-25
Publication
First Author: Yang YL
Year: 1995
Journal: EMBO J
Title: Deficient signaling in mice devoid of double-stranded RNA-dependent protein kinase.
Volume: 14
Issue: 24
Pages: 6095-106
Publication
First Author: Zhu Z
Year: 2015
Journal: Am J Physiol Endocrinol Metab
Title: Inhibition of PKR impairs angiogenesis through a VEGF pathway.
Volume: 308
Issue: 6
Pages: E518-24
Publication
First Author: Kadereit S
Year: 2000
Journal: J Immunol
Title: Negative regulation of CD8+ T cell function by the IFN-induced and double-stranded RNA-activated kinase PKR.
Volume: 165
Issue: 12
Pages: 6896-901
Publication
First Author: Ventoso I
Year: 2012
Journal: J Virol
Title: Adaptive changes in alphavirus mRNA translation allowed colonization of vertebrate hosts.
Volume: 86
Issue: 17
Pages: 9484-94
Publication  
First Author: Yim HCH
Year: 2023
Journal: Front Immunol
Title: The protein kinase R modifies gut physiology to limit colitis.
Volume: 14
Pages: 1106737
Publication
First Author: Scheuner D
Year: 2003
Journal: Virology
Title: The double-stranded RNA-activated protein kinase mediates viral-induced encephalitis.
Volume: 317
Issue: 2
Pages: 263-74
Publication
First Author: Kumar A
Year: 1997
Journal: EMBO J
Title: Deficient cytokine signaling in mouse embryo fibroblasts with a targeted deletion in the PKR gene: role of IRF-1 and NF-kappaB.
Volume: 16
Issue: 2
Pages: 406-16
Publication
First Author: Pereira RM
Year: 2010
Journal: FASEB J
Title: Novel role for the double-stranded RNA-activated protein kinase PKR: modulation of macrophage infection by the protozoan parasite Leishmania.
Volume: 24
Issue: 2
Pages: 617-26
Publication
First Author: Mundhra S
Year: 2018
Journal: Eur J Immunol
Title: Evidence for dispensability of protein kinase R in host control of tuberculosis.
Volume: 48
Issue: 4
Pages: 612-620
Publication
First Author: Baltzis D
Year: 2002
Journal: J Biol Chem
Title: Functional characterization of pkr gene products expressed in cells from mice with a targeted deletion of the N terminus or C terminus domain of PKR.
Volume: 277
Issue: 41
Pages: 38364-72
Publication  
First Author: Lancaster GI
Year: 2016
Journal: Nat Commun
Title: PKR is not obligatory for high-fat diet-induced obesity and its associated metabolic and inflammatory complications.
Volume: 7
Pages: 10626
Publication
First Author: Ostermann E
Year: 2015
Journal: J Virol
Title: Knockout of the Host Resistance Gene Pkr Fully Restores Replication of Murine Cytomegalovirus m142 and m143 Mutants In Vivo.
Volume: 90
Issue: 2
Pages: 1144-7
Publication
First Author: Abraham N
Year: 1999
Journal: J Biol Chem
Title: Characterization of transgenic mice with targeted disruption of the catalytic domain of the double-stranded RNA-dependent protein kinase, PKR.
Volume: 274
Issue: 9
Pages: 5953-62
Publication
First Author: Balachandran S
Year: 2000
Journal: Immunity
Title: Essential role for the dsRNA-dependent protein kinase PKR in innate immunity to viral infection.
Volume: 13
Issue: 1
Pages: 129-41
Publication
First Author: Wang H
Year: 2014
Journal: Circulation
Title: Double-stranded RNA-dependent protein kinase deficiency protects the heart from systolic overload-induced congestive heart failure.
Volume: 129
Issue: 13
Pages: 1397-406
Publication
First Author: Peng Z
Year: 2023
Journal: iScience
Title: PKR deficiency delays vascular aging via inhibiting GSDMD-mediated endothelial cell hyperactivation.
Volume: 26
Issue: 1
Pages: 105909
Publication
First Author: Yang Y
Year: 2021
Journal: J Innate Immun
Title: Double-Stranded RNA Dependent Kinase R Regulates Antibacterial Immunity in Sepsis.
Volume: 13
Issue: 1
Pages: 26-37
Publication
First Author: Yim HC
Year: 2016
Journal: Cell Res
Title: The kinase activity of PKR represses inflammasome activity.
Volume: 26
Issue: 3
Pages: 367-79
Publication
First Author: Tanaka H
Year: 2000
Journal: Gene
Title: Mouse interferon-inducible RNA-dependent protein kinase Pkr gene: cloning and sequence of the 5'-flanking region and functional identification of the minimal inducible promoter.
Volume: 246
Issue: 1-2
Pages: 373-82
Publication
First Author: Patel RC
Year: 1992
Journal: J Interferon Res
Title: Construction and expression of an enzymatically active human-mouse chimeric double-stranded RNA-dependent protein kinase.
Volume: 12
Issue: 5
Pages: 389-93
Publication
First Author: Samuel CE
Year: 1993
Journal: J Biol Chem
Title: The eIF-2 alpha protein kinases, regulators of translation in eukaryotes from yeasts to humans.
Volume: 268
Issue: 11
Pages: 7603-6
Publication
First Author: Barber GN
Year: 1993
Journal: Genomics
Title: Chromosomal assignment of the interferon-inducible double-stranded RNA-dependent protein kinase (PRKR) to human chromosome 2p21-p22 and mouse chromosome 17 E2.
Volume: 16
Issue: 3
Pages: 765-7
Publication
First Author: Baier LJ
Year: 1993
Journal: Nucleic Acids Res
Title: The mouse antiphosphotyrosine immunoreactive kinase, TIK, is indistinguishable from the double-stranded RNA-dependent, interferon-induced protein kinase, PKR.
Volume: 21
Issue: 20
Pages: 4830-5
Publication
First Author: Chen JJ
Year: 1995
Journal: Trends Biochem Sci
Title: Regulation of protein synthesis by heme-regulated eIF-2 alpha kinase.
Volume: 20
Issue: 3
Pages: 105-8
Publication
First Author: Kuhen KL
Year: 1996
Journal: Genomics
Title: Structural organization of the human gene (PKR) encoding an interferon-inducible RNA-dependent protein kinase (PKR) and differences from its mouse homolog.
Volume: 36
Issue: 1
Pages: 197-201
Publication
First Author: Raveh T
Year: 1996
Journal: J Biol Chem
Title: Double-stranded RNA-dependent protein kinase mediates c-Myc suppression induced by type I interferons.
Volume: 271
Issue: 41
Pages: 25479-84
Publication
First Author: Kuhen KL
Year: 1996
Journal: Gene
Title: Mechanism of interferon action sequence of the human interferon-inducible RNA-dependent protein kinase (PKR) deduced from genomic clones.
Volume: 178
Issue: 1-2
Pages: 191-3
Publication
First Author: Kuhen KL
Year: 1997
Journal: Virology
Title: Isolation of the interferon-inducible RNA-dependent protein kinase Pkr promoter and identification of a novel DNA element within the 5'-flanking region of human and mouse Pkr genes.
Volume: 227
Issue: 1
Pages: 119-30
Publication
First Author: Al-Khatib K
Year: 2004
Journal: J Immunol
Title: Distinctive roles for 2',5'-oligoadenylate synthetases and double-stranded RNA-dependent protein kinase R in the in vivo antiviral effect of an adenoviral vector expressing murine IFN-beta.
Volume: 172
Issue: 9
Pages: 5638-47
Publication
First Author: Yoshida K
Year: 2005
Journal: Exp Cell Res
Title: Double-stranded RNA-dependent protein kinase is required for bone calcification in MC3T3-E1 cells in vitro.
Volume: 311
Issue: 1
Pages: 117-25
Publication
First Author: Goplen N
Year: 2008
Journal: J Immunol
Title: A phosphosite screen identifies autocrine TGF-beta-driven activation of protein kinase R as a survival-limiting factor for eosinophils.
Volume: 180
Issue: 6
Pages: 4256-64
Publication
First Author: Anderson BR
Year: 2010
Journal: Nucleic Acids Res
Title: Incorporation of pseudouridine into mRNA enhances translation by diminishing PKR activation.
Volume: 38
Issue: 17
Pages: 5884-92
Publication  
First Author: Okamoto K
Year: 2018
Journal: Commun Biol
Title: APOL1 risk allele RNA contributes to renal toxicity by activating protein kinase R.
Volume: 1
Pages: 188
Publication  
First Author: Mouton-Liger F
Year: 2015
Journal: Cell Death Dis
Title: PKR downregulation prevents neurodegeneration and β-amyloid production in a thiamine-deficient model.
Volume: 6
Pages: e1594
Publication
First Author: Morimoto H
Year: 2013
Journal: Cell Tissue Res
Title: Double-stranded RNA-dependent protein kinase regulates insulin-stimulated chondrogenesis in mouse clonal chondrogenic cells, ATDC-5.
Volume: 351
Issue: 1
Pages: 41-7
GXD Expression      
Probe: MGI:3615125
Assay Type: RT-PCR
Annotation Date: 2006-03-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689421
Stage: TS21
Assay Id: MGI:3616665
Age: embryonic day 13.5
Specimen Label: RT-PCR E13.5 brain
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:3615125
Assay Type: RT-PCR
Annotation Date: 2006-03-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689427
Stage: TS27
Assay Id: MGI:3616665
Age: postnatal day 0
Specimen Label: RT-PCR P0 brain
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:3700241
Assay Type: RT-PCR
Annotation Date: 2007-03-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:3700245
Age: postnatal
Image: 6
Specimen Label: Heart
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:3700241
Assay Type: RT-PCR
Annotation Date: 2007-03-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:3700245
Age: postnatal
Image: 6
Specimen Label: Brain
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:3700241
Assay Type: RT-PCR
Annotation Date: 2007-03-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:3700245
Age: postnatal
Image: 6
Specimen Label: Spleen
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:3700241
Assay Type: RT-PCR
Annotation Date: 2007-03-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672828
Stage: TS28
Assay Id: MGI:3700245
Age: postnatal
Image: 6
Specimen Label: Lung
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:3700241
Assay Type: RT-PCR
Annotation Date: 2007-03-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:3700245
Age: postnatal
Image: 6
Specimen Label: Liver
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:3700241
Assay Type: RT-PCR
Annotation Date: 2007-03-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3598828
Stage: TS28
Assay Id: MGI:3700245
Age: postnatal
Image: 6
Specimen Label: Skeletal muscle
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:3700241
Assay Type: RT-PCR
Annotation Date: 2007-03-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:3700245
Age: postnatal
Image: 6
Specimen Label: Kidney
Detected: true
Specimen Num: 7
GXD Expression    
Probe: MGI:3700241
Assay Type: RT-PCR
Annotation Date: 2007-03-20
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:3700245
Age: postnatal
Image: 6
Specimen Label: Testis
Detected: true
Specimen Num: 8
GXD Expression    
Probe: MGI:3700241
Assay Type: RT-PCR
Annotation Date: 2007-03-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603910
Stage: TS10
Assay Id: MGI:3700245
Age: embryonic day 7.0
Image: 6
Specimen Label: 7 day embryo
Detected: true
Specimen Num: 9
GXD Expression    
Probe: MGI:3700241
Assay Type: RT-PCR
Annotation Date: 2007-03-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603918
Stage: TS18
Assay Id: MGI:3700245
Age: embryonic day 11.0
Image: 6
Specimen Label: 11 day embryo
Detected: true
Specimen Num: 10
GXD Expression    
Probe: MGI:3700241
Assay Type: RT-PCR
Annotation Date: 2007-03-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603923
Stage: TS23
Assay Id: MGI:3700245
Age: embryonic day 15.0
Image: 6
Specimen Label: 15 day embryo
Detected: true
Specimen Num: 11
GXD Expression    
Probe: MGI:3700241
Assay Type: RT-PCR
Annotation Date: 2007-03-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603925
Stage: TS25
Assay Id: MGI:3700245
Age: embryonic day 17.0
Image: 6
Specimen Label: 17 day embryo
Detected: true
Specimen Num: 12
GXD Expression    
Probe: MGI:6385888
Assay Type: RT-PCR
Annotation Date: 2020-01-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603919
Stage: TS19
Assay Id: MGI:6386184
Age: embryonic day 11.5
Image: 3
Specimen Label: wild type
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:6385888
Assay Type: RT-PCR
Annotation Date: 2020-01-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603919
Stage: TS19
Assay Id: MGI:6386184
Age: embryonic day 11.5
Image: 3
Specimen Label: Adar1-/-
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:6385888
Assay Type: RT-PCR
Annotation Date: 2020-01-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603919
Stage: TS19
Assay Id: MGI:6386184
Age: embryonic day 11.5
Image: 3
Specimen Label: Adar1-/-;Ifnar1-/-
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:6385888
Assay Type: RT-PCR
Annotation Date: 2020-01-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603919
Stage: TS19
Assay Id: MGI:6386184
Age: embryonic day 11.5
Image: 3
Specimen Label: Adar1-/-;Mavs-/-
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:6385888
Assay Type: RT-PCR
Annotation Date: 2020-01-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603919
Stage: TS19
Assay Id: MGI:6386227
Age: embryonic day 11.5
Image: S2
Specimen Label: wild type
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:6385888
Assay Type: RT-PCR
Annotation Date: 2020-01-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603919
Stage: TS19
Assay Id: MGI:6386227
Age: embryonic day 11.5
Image: S2
Specimen Label: Ifnar1-/-
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:6385888
Assay Type: RT-PCR
Annotation Date: 2020-01-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603919
Stage: TS19
Assay Id: MGI:6386227
Age: embryonic day 11.5
Image: S2
Specimen Label: Mavs-/-
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:3615823
Assay Type: RNA in situ
Annotation Date: 2006-03-22
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1665821
Stage: TS21
Assay Id: MGI:3617367
Age: embryonic day 13.5
Image: E13.5
Specimen Label: E13.5
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:3615823
Assay Type: RNA in situ
Annotation Date: 2006-03-22
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1691621
Stage: TS21
Assay Id: MGI:3617367
Age: embryonic day 13.5
Image: E13.5
Specimen Label: E13.5
Detected: false
Specimen Num: 1
GXD Expression  
Probe: MGI:3615823
Assay Type: RNA in situ
Annotation Date: 2006-03-22
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:1691627
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:3617367
Age: postnatal day 0
Image: P0
Note: Authors indicate that there was either ubiquitous or background expression.
Specimen Label: P0
Specimen Num: 2