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Search results 1 to 100 out of 249 for Eif2ak4

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0.037s
Type Details Score
Gene
Type: gene
Organism: Homo sapiens
Gene
Type: gene
Organism: Rattus norvegicus
Gene
Type: gene
Organism: Danio rerio
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Gene
Type: gene
Organism: Homo sapiens
Publication
First Author: Roffé M
Year: 2013
Journal: J Biol Chem
Title: IMPACT is a developmentally regulated protein in neurons that opposes the eukaryotic initiation factor 2α kinase GCN2 in the modulation of neurite outgrowth.
Volume: 288
Issue: 15
Pages: 10860-9
Gene
Type: gene
Organism: Rattus norvegicus
Gene
Type: gene
Organism: Danio rerio
Publication
First Author: Pereira CM
Year: 2005
Journal: J Biol Chem
Title: IMPACT, a protein preferentially expressed in the mouse brain, binds GCN1 and inhibits GCN2 activation.
Volume: 280
Issue: 31
Pages: 28316-23
Publication
First Author: Cambiaghi TD
Year: 2014
Journal: Biochem Biophys Res Commun
Title: Evolutionarily conserved IMPACT impairs various stress responses that require GCN1 for activating the eIF2 kinase GCN2.
Volume: 443
Issue: 2
Pages: 592-7
Publication
First Author: Yamazaki H
Year: 2020
Journal: PLoS Genet
Title: Ribosome binding protein GCN1 regulates the cell cycle and cell proliferation and is essential for the embryonic development of mice.
Volume: 16
Issue: 4
Pages: e1008693
Publication  
First Author: Kanno A
Year: 2020
Journal: JCI Insight
Title: GCN2 regulates pancreatic β cell mass by sensing intracellular amino acid levels.
Volume: 5
Issue: 9
Publication      
First Author: Beutler B
Year: 2011
Journal: MGI Direct Data Submission
Title: Direct Data Submission 2011/07/19
Publication
First Author: Bretin A
Year: 2018
Journal: Sci Rep
Title: AIEC infection triggers modification of gut microbiota composition in genetically predisposed mice, contributing to intestinal inflammation.
Volume: 8
Issue: 1
Pages: 12301
Publication
First Author: Won S
Year: 2012
Journal: J Virol
Title: Increased susceptibility to DNA virus infection in mice with a GCN2 mutation.
Volume: 86
Issue: 3
Pages: 1802-8
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Berlanga JJ
Year: 1999
Journal: Eur J Biochem
Title: Characterization of a mammalian homolog of the GCN2 eukaryotic initiation factor 2alpha kinase.
Volume: 265
Issue: 2
Pages: 754-62
Publication
First Author: Sood R
Year: 2000
Journal: Genetics
Title: A mammalian homologue of GCN2 protein kinase important for translational control by phosphorylation of eukaryotic initiation factor-2alpha.
Volume: 154
Issue: 2
Pages: 787-801
Publication
First Author: Zhang P
Year: 2002
Journal: Mol Cell Biol
Title: The GCN2 eIF2alpha kinase is required for adaptation to amino acid deprivation in mice.
Volume: 22
Issue: 19
Pages: 6681-8
Publication
First Author: Anthony TG
Year: 2004
Journal: J Biol Chem
Title: Preservation of liver protein synthesis during dietary leucine deprivation occurs at the expense of skeletal muscle mass in mice deleted for eIF2 kinase GCN2.
Volume: 279
Issue: 35
Pages: 36553-61
Publication
First Author: Maurin AC
Year: 2005
Journal: Cell Metab
Title: The GCN2 kinase biases feeding behavior to maintain amino acid homeostasis in omnivores.
Volume: 1
Issue: 4
Pages: 273-7
Publication
First Author: Costa-Mattioli M
Year: 2005
Journal: Nature
Title: Translational control of hippocampal synaptic plasticity and memory by the eIF2alpha kinase GCN2.
Volume: 436
Issue: 7054
Pages: 1166-73
Publication
First Author: Berlanga JJ
Year: 2006
Journal: EMBO J
Title: Antiviral effect of the mammalian translation initiation factor 2alpha kinase GCN2 against RNA viruses.
Volume: 25
Issue: 8
Pages: 1730-40
Publication
First Author: Dever TE
Year: 1992
Journal: Cell
Title: Phosphorylation of initiation factor 2 alpha by protein kinase GCN2 mediates gene-specific translational control of GCN4 in yeast.
Volume: 68
Issue: 3
Pages: 585-96
Publication
First Author: Wilson GJ
Year: 2015
Journal: Am J Physiol Endocrinol Metab
Title: GCN2 is required to increase fibroblast growth factor 21 and maintain hepatic triglyceride homeostasis during asparaginase treatment.
Volume: 308
Issue: 4
Pages: E283-93
Publication
First Author: Fletcher M
Year: 2015
Journal: Cancer Res
Title: l-Arginine depletion blunts antitumor T-cell responses by inducing myeloid-derived suppressor cells.
Volume: 75
Issue: 2
Pages: 275-83
Publication
First Author: Ye J
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Pyruvate kinase M2 promotes de novo serine synthesis to sustain mTORC1 activity and cell proliferation.
Volume: 109
Issue: 18
Pages: 6904-9
Publication
First Author: Leib DE
Year: 2016
Journal: Cell Rep
Title: Rapid Sensing of Dietary Amino Acid Deficiency Does Not Require GCN2.
Volume: 16
Issue: 8
Pages: 2051-2052
Publication
First Author: Sun ZG
Year: 2020
Journal: Int Heart J
Title: Exercise Preconditioning Protects against Acute Cardiac Injury Induced by Lipopolysaccharide Through General Control Nonderepressible 2 Kinase.
Volume: 61
Issue: 1
Pages: 138-144
Publication
First Author: Liu S
Year: 2018
Journal: Biochim Biophys Acta Mol Basis Dis
Title: GCN2 deficiency protects against high fat diet induced hepatic steatosis and insulin resistance in mice.
Volume: 1864
Issue: 10
Pages: 3257-3267
Publication
First Author: Lu Z
Year: 2014
Journal: Hypertension
Title: Loss of the eukaryotic initiation factor 2α kinase general control nonderepressible 2 protects mice from pressure overload-induced congestive heart failure without affecting ventricular hypertrophy.
Volume: 63
Issue: 1
Pages: 128-35
Publication
First Author: Highfill SL
Year: 2010
Journal: Blood
Title: Bone marrow myeloid-derived suppressor cells (MDSCs) inhibit graft-versus-host disease (GVHD) via an arginase-1-dependent mechanism that is up-regulated by interleukin-13.
Volume: 116
Issue: 25
Pages: 5738-47
Publication
First Author: Iken K
Year: 2012
Journal: Am J Respir Cell Mol Biol
Title: Indoleamine 2,3-dioxygenase and metabolites protect murine lung allografts and impair the calcium mobilization of T cells.
Volume: 47
Issue: 4
Pages: 405-16
Publication
First Author: Leib DE
Year: 2015
Journal: Cell Rep
Title: Re-examination of Dietary Amino Acid Sensing Reveals a GCN2-Independent Mechanism.
Volume: 13
Issue: 6
Pages: 1081-1089
Publication
First Author: Marion V
Year: 2011
Journal: J Biol Chem
Title: Arginine deficiency causes runting in the suckling period by selectively activating the stress kinase GCN2.
Volume: 286
Issue: 11
Pages: 8866-74
Publication
First Author: Devi L
Year: 2013
Journal: PLoS One
Title: Deletion of the eIF2α Kinase GCN2 fails to rescue the memory decline associated with Alzheimer's disease.
Volume: 8
Issue: 10
Pages: e77335
Publication
First Author: Kim Y
Year: 2020
Journal: Proc Natl Acad Sci U S A
Title: Aminoacyl-tRNA synthetase inhibition activates a pathway that branches from the canonical amino acid response in mammalian cells.
Volume: 117
Issue: 16
Pages: 8900-8911
Publication
First Author: Peng W
Year: 2012
Journal: Sci Transl Med
Title: Surgical stress resistance induced by single amino acid deprivation requires Gcn2 in mice.
Volume: 4
Issue: 118
Pages: 118ra11
Publication
First Author: Fallarino F
Year: 2006
Journal: J Immunol
Title: The combined effects of tryptophan starvation and tryptophan catabolites down-regulate T cell receptor zeta-chain and induce a regulatory phenotype in naive T cells.
Volume: 176
Issue: 11
Pages: 6752-61
Publication
First Author: Yu J
Year: 2013
Journal: Diabetes
Title: PRLR regulates hepatic insulin sensitivity in mice via STAT5.
Volume: 62
Issue: 9
Pages: 3103-13
Publication
First Author: Guo F
Year: 2007
Journal: Cell Metab
Title: The GCN2 eIF2alpha kinase regulates fatty-acid homeostasis in the liver during deprivation of an essential amino acid.
Volume: 5
Issue: 2
Pages: 103-14
Publication
First Author: Bunpo P
Year: 2010
Journal: J Nutr
Title: The eIF2 kinase GCN2 is essential for the murine immune system to adapt to amino acid deprivation by asparaginase.
Volume: 140
Issue: 11
Pages: 2020-7
Publication
First Author: Wilson GJ
Year: 2013
Journal: Am J Physiol Endocrinol Metab
Title: The eukaryotic initiation factor 2 kinase GCN2 protects against hepatotoxicity during asparaginase treatment.
Volume: 305
Issue: 9
Pages: E1124-33
Publication
First Author: Xu X
Year: 2013
Journal: PLoS One
Title: GCN2 in the brain programs PPARγ2 and triglyceride storage in the liver during perinatal development in response to maternal dietary fat.
Volume: 8
Issue: 10
Pages: e75917
Publication
First Author: Chalvon-Demersay T
Year: 2019
Journal: Am J Physiol Endocrinol Metab
Title: Liver GCN2 controls hepatic FGF21 secretion and modulates whole body postprandial oxidation profile under a low-protein diet.
Volume: 317
Issue: 6
Pages: E1015-E1021
Publication
First Author: Phillipson-Weiner L
Year: 2016
Journal: Am J Physiol Gastrointest Liver Physiol
Title: General control nonderepressible 2 deletion predisposes to asparaginase-associated pancreatitis in mice.
Volume: 310
Issue: 11
Pages: G1061-70
Publication
First Author: Wang P
Year: 2019
Journal: J Allergy Clin Immunol
Title: The amino acid sensor general control nonderepressible 2 (GCN2) controls TH9 cells and allergic airway inflammation.
Volume: 144
Issue: 4
Pages: 1091-1105
GXD Expression    
Probe: MGI:6436589
Assay Type: RT-PCR
Annotation Date: 2020-06-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876726
Stage: TS26
Assay Id: MGI:6436594
Age: embryonic day 18.5
Image: S1
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:6436589
Assay Type: RT-PCR
Annotation Date: 2020-06-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737326
Stage: TS26
Assay Id: MGI:6436594
Age: embryonic day 18.5
Image: S1
Detected: true
Specimen Num: 10
GXD Expression    
Probe: MGI:6436589
Assay Type: RT-PCR
Annotation Date: 2020-06-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672826
Stage: TS26
Assay Id: MGI:6436594
Age: embryonic day 18.5
Image: S1
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:6436589
Assay Type: RT-PCR
Annotation Date: 2020-06-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610526
Stage: TS26
Assay Id: MGI:6436594
Age: embryonic day 18.5
Image: S1
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:6436589
Assay Type: RT-PCR
Annotation Date: 2020-06-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684626
Stage: TS26
Assay Id: MGI:6436594
Age: embryonic day 18.5
Image: S1
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:6436589
Assay Type: RT-PCR
Annotation Date: 2020-06-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1750326
Stage: TS26
Assay Id: MGI:6436594
Age: embryonic day 18.5
Image: S1
Detected: true
Specimen Num: 7
GXD Expression    
Probe: MGI:6436589
Assay Type: RT-PCR
Annotation Date: 2020-06-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3287426
Stage: TS26
Assay Id: MGI:6436594
Age: embryonic day 18.5
Image: S1
Detected: true
Specimen Num: 9
GXD Expression    
Probe: MGI:6436589
Assay Type: RT-PCR
Annotation Date: 2020-06-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876826
Stage: TS26
Assay Id: MGI:6436594
Age: embryonic day 18.5
Image: S1
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:6436589
Assay Type: RT-PCR
Annotation Date: 2020-06-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1702126
Stage: TS26
Assay Id: MGI:6436594
Age: embryonic day 18.5
Image: S1
Detected: true
Specimen Num: 8
GXD Expression      
Probe: MGI:4366299
Assay Type: RT-PCR
Annotation Date: 2009-11-04
Strength: Present
Sex: Female
Emaps: EMAPS:3102528
Stage: TS28
Assay Id: MGI:4366300
Age: postnatal day 25
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:4366301
Assay Type: RT-PCR
Annotation Date: 2009-11-04
Strength: Absent
Sex: Female
Emaps: EMAPS:3102528
Stage: TS28
Assay Id: MGI:4366304
Age: postnatal day 25
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:4366302
Assay Type: RT-PCR
Annotation Date: 2009-11-04
Strength: Present
Sex: Female
Emaps: EMAPS:3102528
Stage: TS28
Assay Id: MGI:4366305
Age: postnatal day 25
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:4366301
Assay Type: RT-PCR
Annotation Date: 2009-11-04
Strength: Absent
Sex: Female
Emaps: EMAPS:3102528
Stage: TS28
Assay Id: MGI:4366306
Age: postnatal day 25
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:4366302
Assay Type: RT-PCR
Annotation Date: 2009-11-04
Strength: Present
Sex: Female
Emaps: EMAPS:3102528
Stage: TS28
Assay Id: MGI:4366307
Age: postnatal day 25
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:4366296
Assay Type: Western blot
Annotation Date: 2009-11-04
Strength: Present
Sex: Female
Emaps: EMAPS:3102528
Stage: TS28
Assay Id: MGI:4366308
Age: postnatal
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:4366298
Assay Type: Western blot
Annotation Date: 2009-11-04
Strength: Present
Sex: Female
Emaps: EMAPS:3102528
Stage: TS28
Assay Id: MGI:4366309
Age: postnatal
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:4366296
Assay Type: Western blot
Annotation Date: 2009-11-04
Strength: Present
Sex: Female
Emaps: EMAPS:3102528
Stage: TS28
Assay Id: MGI:4366311
Age: postnatal
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:4366298
Assay Type: Western blot
Annotation Date: 2009-11-04
Strength: Present
Sex: Female
Emaps: EMAPS:3102528
Stage: TS28
Assay Id: MGI:4366312
Age: postnatal
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:4366299
Assay Type: RT-PCR
Annotation Date: 2009-11-04
Strength: Absent
Sex: Female
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:4366300
Age: postnatal day 25
Detected: false
Specimen Num: 2
GXD Expression      
Probe: MGI:4366301
Assay Type: RT-PCR
Annotation Date: 2009-11-04
Strength: Present
Sex: Female
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:4366304
Age: postnatal day 25
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:4366302
Assay Type: RT-PCR
Annotation Date: 2009-11-04
Strength: Present
Sex: Female
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:4366305
Age: postnatal day 25
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:4366301
Assay Type: RT-PCR
Annotation Date: 2009-11-04
Strength: Present
Sex: Female
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:4366306
Age: postnatal day 25
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:4366302
Assay Type: RT-PCR
Annotation Date: 2009-11-04
Strength: Present
Sex: Female
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:4366307
Age: postnatal day 25
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:6436589
Assay Type: RT-PCR
Annotation Date: 2020-06-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689426
Stage: TS26
Assay Id: MGI:6436594
Age: embryonic day 18.5
Image: S1
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:4366301
Assay Type: RT-PCR
Annotation Date: 2009-11-04
Strength: Present
Sex: Female
Emaps: EMAPS:1796228
Stage: TS28
Assay Id: MGI:4366304
Age: postnatal day 25
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:4366301
Assay Type: RT-PCR
Annotation Date: 2009-11-04
Strength: Present
Sex: Female
Emaps: EMAPS:1796228
Stage: TS28
Assay Id: MGI:4366304
Age: postnatal day 25
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:4366302
Assay Type: RT-PCR
Annotation Date: 2009-11-04
Strength: Present
Sex: Female
Emaps: EMAPS:1796228
Stage: TS28
Assay Id: MGI:4366305
Age: postnatal day 25
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:4366302
Assay Type: RT-PCR
Annotation Date: 2009-11-04
Strength: Present
Sex: Female
Emaps: EMAPS:1796228
Stage: TS28
Assay Id: MGI:4366305
Age: postnatal day 25
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:4366301
Assay Type: RT-PCR
Annotation Date: 2009-11-04
Strength: Present
Sex: Female
Emaps: EMAPS:1796228
Stage: TS28
Assay Id: MGI:4366306
Age: postnatal day 25
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:4366301
Assay Type: RT-PCR
Annotation Date: 2009-11-04
Strength: Present
Sex: Female
Emaps: EMAPS:1796228
Stage: TS28
Assay Id: MGI:4366306
Age: postnatal day 25
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:4366302
Assay Type: RT-PCR
Annotation Date: 2009-11-04
Strength: Present
Sex: Female
Emaps: EMAPS:1796228
Stage: TS28
Assay Id: MGI:4366307
Age: postnatal day 25
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:4366302
Assay Type: RT-PCR
Annotation Date: 2009-11-04
Strength: Present
Sex: Female
Emaps: EMAPS:1796228
Stage: TS28
Assay Id: MGI:4366307
Age: postnatal day 25
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:4366296
Assay Type: Western blot
Annotation Date: 2009-11-04
Strength: Present
Sex: Female
Emaps: EMAPS:1796228
Stage: TS28
Assay Id: MGI:4366313
Age: postnatal
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:4366296
Assay Type: Western blot
Annotation Date: 2009-11-04
Strength: Present
Sex: Female
Emaps: EMAPS:1796228
Stage: TS28
Assay Id: MGI:4366313
Age: postnatal
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:4366298
Assay Type: Western blot
Annotation Date: 2009-11-04
Strength: Present
Sex: Female
Emaps: EMAPS:1796228
Stage: TS28
Assay Id: MGI:4366314
Age: postnatal
Detected: true
Specimen Num: 1