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Search results 1 to 100 out of 194 for Elane

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Type Details Score
Gene
1991 | ELANE
Type: gene
Organism: human
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Gene
100126050 | ELANE
Type: gene
Organism: cattle
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Gene
106992354 | ELANE
Type: gene
Organism: macaque, rhesus
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Gene
129138043 | ELANE
Type: gene
Organism: chimpanzee
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Gene
299606 | Elane
Type: gene
Organism: rat
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Gene
442980 | ELANE
Type: gene
Organism: dog, domestic
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Protein Coding Gene
MGI:2679229 | Elane
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
32299910 | J:299482
First Author: Garg B
Year: 2020
Journal: J Biol Chem
Title: Inducible expression of a disease-associated ELANE mutation impairs granulocytic differentiation, without eliciting an unfolded protein response.
Volume: 295
Issue: 21
Pages: 7492-7500
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Publication
33964209 | J:307143
First Author: Cui C
Year: 2021
Journal: Cell
Title: Neutrophil elastase selectively kills cancer cells and attenuates tumorigenesis.
Volume: 184
Issue: 12
Pages: 3163-3177.e21
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Publication
32415172 | J:293232
First Author: Klinke M
Year: 2020
Journal: Sci Rep
Title: Development of an improved murine model of necrotizing enterocolitis shows the importance of neutrophils in NEC pathogenesis.
Volume: 10
Issue: 1
Pages: 8049
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Publication
18568075 | J:137674
First Author: Kessenbrock K
Year: 2008
Journal: J Clin Invest
Title: Proteinase 3 and neutrophil elastase enhance inflammation in mice by inactivating antiinflammatory progranulin.
Volume: 118
Issue: 7
Pages: 2438-47
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Publication
22213227 | J:187789
First Author: Mankan AK
Year: 2012
Journal: Eur J Immunol
Title: The NLRP3/ASC/Caspase-1 axis regulates IL-1β processing in neutrophils.
Volume: 42
Issue: 3
Pages: 710-5
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Publication
32243431 | J:289970
First Author: Gordon RA
Year: 2020
Journal: PLoS One
Title: Murine lupus is neutrophil elastase-independent in the MRL.Faslpr model.
Volume: 15
Issue: 4
Pages: e0226396
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Publication
21285438 | J:170501
First Author: Nanua S
Year: 2011
Journal: Blood
Title: Activation of the unfolded protein response is associated with impaired granulopoiesis in transgenic mice expressing mutant Elane.
Volume: 117
Issue: 13
Pages: 3539-47
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Publication
24929239 | J:213567
First Author: Guyot N
Year: 2014
Journal: Am J Pathol
Title: Unopposed cathepsin G, neutrophil elastase, and proteinase 3 cause severe lung damage and emphysema.
Volume: 184
Issue: 8
Pages: 2197-210
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Publication
22241891 | J:264172
First Author: Schreiber A
Year: 2012
Journal: J Am Soc Nephrol
Title: Neutrophil serine proteases promote IL-1β generation and injury in necrotizing crescentic glomerulonephritis.
Volume: 23
Issue: 3
Pages: 470-82
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Publication
32002713 | J:296047
First Author: Mirea AM
Year: 2020
Journal: Inflammation
Title: Mice Deficient in the IL-1β Activation Genes Prtn3, Elane, and Casp1 Are Protected Against the Development of Obesity-Induced NAFLD.
Volume: 43
Issue: 3
Pages: 1054-1064
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Publication
21160041 | J:168769
First Author: Croker BA
Year: 2011
Journal: J Immunol
Title: Neutrophils require SHP1 to regulate IL-1β production and prevent inflammatory skin disease.
Volume: 186
Issue: 2
Pages: 1131-9
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Publication
28192517 | J:245406
First Author: Dai R
Year: 2017
Journal: PLoS One
Title: Neutrophils and neutrophil serine proteases are increased in the spleens of estrogen-treated C57BL/6 mice and several strains of spontaneous lupus-prone mice.
Volume: 12
Issue: 2
Pages: e0172105
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Publication
25274309 | J:217490
First Author: Lukens JR
Year: 2014
Journal: Nature
Title: Dietary modulation of the microbiome affects autoinflammatory disease.
Volume: 516
Issue: 7530
Pages: 246-9
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Publication
27551156 | J:237236
First Author: Qi X
Year: 2016
Journal: J Exp Med
Title: Cathepsin B modulates lysosomal biogenesis and host defense against Francisella novicida infection.
Volume: 213
Issue: 10
Pages: 2081-97
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Protein Coding Gene
MGP_CAROLIEiJ_G0015548 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0017466 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0017444 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0017405 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0017406 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0017229 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_2679229 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0017860 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0016796 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0017201 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0017307 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0017301 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0017378 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0017327 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0017901 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0016577 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0016856 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0030961 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0016366 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
35221334 | J:321216
First Author: Nolan E
Year: 2022
Journal: Nat Cancer
Title: Radiation exposure elicits a neutrophil-driven response in healthy lung tissue that enhances metastatic colonization.
Volume: 3
Issue: 2
Pages: 173-187
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Publication
17200183 | J:117047
First Author: Chua F
Year: 2007
Journal: Am J Pathol
Title: Mice lacking neutrophil elastase are resistant to bleomycin-induced pulmonary fibrosis.
Volume: 170
Issue: 1
Pages: 65-74
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Publication
9585238 | J:47420
First Author: Belaaouaj A
Year: 1998
Journal: Nat Med
Title: Mice lacking neutrophil elastase reveal impaired host defense against gram negative bacterial sepsis.
Volume: 4
Issue: 5
Pages: 615-8
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Publication
22863787 | J:192787
First Author: Talukdar S
Year: 2012
Journal: Nat Med
Title: Neutrophils mediate insulin resistance in mice fed a high-fat diet through secreted elastase.
Volume: 18
Issue: 9
Pages: 1407-12
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Publication
20974816 | J:166722
First Author: Papayannopoulos V
Year: 2010
Journal: J Cell Biol
Title: Neutrophil elastase and myeloperoxidase regulate the formation of neutrophil extracellular traps.
Volume: 191
Issue: 3
Pages: 677-91
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Publication
34643662 | J:319538
First Author: Lessieur EM
Year: 2021
Journal: Invest Ophthalmol Vis Sci
Title: Neutrophil-Derived Proteases Contribute to the Pathogenesis of Early Diabetic Retinopathy.
Volume: 62
Issue: 13
Pages: 7
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Publication
20921524 | J:165180
First Author: Fang H
Year: 2010
Journal: J Immunol
Title: Neutrophil elastase mediates pathogenic effects of anthrax lethal toxin in the murine intestinal tract.
Volume: 185
Issue: 9
Pages: 5463-7
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Publication
25497734 | J:219355
 
First Author: Semple BD
Year: 2015
Journal: Neurobiol Dis
Title: Neutrophil elastase mediates acute pathogenesis and is a determinant of long-term behavioral recovery after traumatic injury to the immature brain.
Volume: 74
Pages: 263-80
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Publication
18772136 | J:143128
First Author: Bergin DA
Year: 2008
Journal: J Biol Chem
Title: Activation of the epidermal growth factor receptor (EGFR) by a novel metalloprotease pathway.
Volume: 283
Issue: 46
Pages: 31736-44
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Publication
14565940 | J:97295
First Author: Hirche TO
Year: 2004
Journal: Am J Respir Cell Mol Biol
Title: Deficiency in neutrophil elastase does not impair neutrophil recruitment to inflamed sites.
Volume: 30
Issue: 4
Pages: 576-84
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Publication
37285400 | J:338061
First Author: Tsai CH
Year: 2023
Journal: Sci Transl Med
Title: Neutrophil extracellular trap production and CCL4L2 expression influence corticosteroid response in asthma.
Volume: 15
Issue: 699
Pages: eadf3843
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Publication
16754715 | J:124377
First Author: Wang S
Year: 2006
Journal: J Exp Med
Title: Venular basement membranes contain specific matrix protein low expression regions that act as exit points for emigrating neutrophils.
Volume: 203
Issue: 6
Pages: 1519-32
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Publication
18802098 | J:142738
First Author: Hirche TO
Year: 2008
Journal: J Immunol
Title: Neutrophil elastase mediates innate host protection against Pseudomonas aeruginosa.
Volume: 181
Issue: 7
Pages: 4945-54
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Publication
25743626 | J:242683
First Author: Gregory AD
Year: 2015
Journal: J Leukoc Biol
Title: Neutrophil elastase promotes myofibroblast differentiation in lung fibrosis.
Volume: 98
Issue: 2
Pages: 143-52
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Publication
30632166 | J:275564
First Author: Voisin MB
Year: 2019
Journal: J Pathol
Title: Neutrophil elastase plays a non-redundant role in remodeling the venular basement membrane and neutrophil diapedesis post-ischemia/reperfusion injury.
Volume: 248
Issue: 1
Pages: 88-102
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Publication
25195861 | J:222523
First Author: Caruso JA
Year: 2015
Journal: Oncogene
Title: The serine protease inhibitor elafin maintains normal growth control by opposing the mitogenic effects of neutrophil elastase.
Volume: 34
Issue: 27
Pages: 3556-67
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Publication
18276796 | J:151216
First Author: Kaynar AM
Year: 2008
Journal: Am J Respir Cell Mol Biol
Title: Neutrophil elastase is needed for neutrophil emigration into lungs in ventilator-induced lung injury.
Volume: 39
Issue: 1
Pages: 53-60
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Publication
32294409 | J:288493
First Author: Jackson-Jones LH
Year: 2020
Journal: Immunity
Title: Stromal Cells Covering Omental Fat-Associated Lymphoid Clusters Trigger Formation of Neutrophil Aggregates to Capture Peritoneal Contaminants.
Volume: 52
Issue: 4
Pages: 700-715.e6
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Publication
- | J:218967
     
First Author: Zhang Z
Year: 2015
Journal: MGI Direct Data Submission
Title: Mutagenetix entry for Ruo
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Publication
20709801 | J:165346
First Author: Ishii T
Year: 2010
Journal: Am J Pathol
Title: Neutrophil elastase contributes to acute lung injury induced by bilateral nephrectomy.
Volume: 177
Issue: 4
Pages: 1665-73
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Publication
21098233 | J:168005
First Author: Faria MS
Year: 2011
Journal: J Immunol
Title: Leishmania inhibitor of serine peptidase 2 prevents TLR4 activation by neutrophil elastase promoting parasite survival in murine macrophages.
Volume: 186
Issue: 1
Pages: 411-22
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Publication
22197976 | J:180766
First Author: Puga I
Year: 2011
Journal: Nat Immunol
Title: B cell-helper neutrophils stimulate the diversification and production of immunoglobulin in the marginal zone of the spleen.
Volume: 13
Issue: 2
Pages: 170-80
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Publication
23975926 | J:201056
First Author: Jonigk D
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Anti-inflammatory and immunomodulatory properties of α1-antitrypsin without inhibition of elastase.
Volume: 110
Issue: 37
Pages: 15007-12
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Publication
31472960 | J:290438
First Author: Chen J
Year: 2019
Journal: Biochem Biophys Res Commun
Title: Knockout of neutrophil elastase protects against western diet induced nonalcoholic steatohepatitis in mice by regulating hepatic ceramides metabolism.
Volume: 518
Issue: 4
Pages: 691-697
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GXD Expression
GXD Expression
   
Probe: MGI:7329829
Assay Type: Western blot
Annotation Date: 2022-08-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1750328
Stage: TS28
Assay Id: MGI:7329894
Age: postnatal week 3
Image: 2
Specimen Label: Ptf1a-cre
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:7329829
Assay Type: Western blot
Annotation Date: 2022-08-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1750328
Stage: TS28
Assay Id: MGI:7329894
Age: postnatal week 3
Image: 2
Specimen Label: Dhps PANC
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:7329829
Assay Type: Western blot
Annotation Date: 2022-08-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1750326
Stage: TS26
Assay Id: MGI:7329906
Age: embryonic day 18.5
Image: 6
Specimen Label: Ptf1a-cre
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:7329829
Assay Type: Western blot
Annotation Date: 2022-08-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1750326
Stage: TS26
Assay Id: MGI:7329906
Age: embryonic day 18.5
Image: 6
Specimen Label: Ptf1a-cre
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:7329829
Assay Type: Western blot
Annotation Date: 2022-08-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1750326
Stage: TS26
Assay Id: MGI:7329906
Age: embryonic day 18.5
Image: 6
Specimen Label: Ptf1a-cre
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:7329829
Assay Type: Western blot
Annotation Date: 2022-08-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1750326
Stage: TS26
Assay Id: MGI:7329906
Age: embryonic day 18.5
Image: 6
Specimen Label: Dhps PANC
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:7329829
Assay Type: Western blot
Annotation Date: 2022-08-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1750326
Stage: TS26
Assay Id: MGI:7329906
Age: embryonic day 18.5
Image: 6
Specimen Label: Dhps PANC
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
   
Probe: MGI:7329829
Assay Type: Western blot
Annotation Date: 2022-08-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1750326
Stage: TS26
Assay Id: MGI:7329906
Age: embryonic day 18.5
Image: 6
Specimen Label: Dhps PANC
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
   
Probe: MGI:7329829
Assay Type: Western blot
Annotation Date: 2022-08-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1750326
Stage: TS26
Assay Id: MGI:7329906
Age: embryonic day 18.5
Image: 6
Specimen Label: Eif5a PANC
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
   
Probe: MGI:7329829
Assay Type: Western blot
Annotation Date: 2022-08-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1750326
Stage: TS26
Assay Id: MGI:7329906
Age: embryonic day 18.5
Image: 6
Specimen Label: Eif5a PANC
Detected: true
Specimen Num: 8
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GXD Expression
GXD Expression
   
Probe: MGI:7329829
Assay Type: Western blot
Annotation Date: 2022-08-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1750326
Stage: TS26
Assay Id: MGI:7329906
Age: embryonic day 18.5
Image: 6
Specimen Label: Eif5a PANC
Detected: true
Specimen Num: 9
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Publication
21464320 | J:171365
First Author: Mankan AK
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: TNF-alpha-dependent loss of IKKbeta-deficient myeloid progenitors triggers a cytokine loop culminating in granulocytosis.
Volume: 108
Issue: 16
Pages: 6567-72
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Publication
9925946 | J:53137
First Author: Sturrock A
Year: 1998
Journal: Cytogenet Cell Genet
Title: Characterization and localization of the genes for mouse proteinase-3 (Prtn3) and neutrophil elastase (Ela2).
Volume: 83
Issue: 1-2
Pages: 104-8
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Publication
26047922 | J:229115
First Author: Colom B
Year: 2015
Journal: Immunity
Title: Leukotriene B4-Neutrophil Elastase Axis Drives Neutrophil Reverse Transendothelial Cell Migration In Vivo.
Volume: 42
Issue: 6
Pages: 1075-86
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Publication
31108101 | J:282263
First Author: Suzuki K
Year: 2019
Journal: Am J Pathol
Title: Neutrophil Elastase Damages the Pulmonary Endothelial Glycocalyx in Lipopolysaccharide-Induced Experimental Endotoxemia.
Volume: 189
Issue: 8
Pages: 1526-1535
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Publication
19752320 | J:167501
First Author: Hirahashi J
Year: 2009
Journal: Circulation
Title: Mac-1 (CD11b/CD18) links inflammation and thrombosis after glomerular injury.
Volume: 120
Issue: 13
Pages: 1255-65
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Publication
21911460 | J:178224
First Author: Hahn I
Year: 2011
Journal: Infect Immun
Title: Cathepsin G and neutrophil elastase play critical and nonredundant roles in lung-protective immunity against Streptococcus pneumoniae in mice.
Volume: 79
Issue: 12
Pages: 4893-901
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Publication
26712312 | J:264223
First Author: Martinod K
Year: 2016
Journal: J Thromb Haemost
Title: Neutrophil elastase-deficient mice form neutrophil extracellular traps in an experimental model of deep vein thrombosis.
Volume: 14
Issue: 3
Pages: 551-8
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Publication
22461690 | J:188458
First Author: Steinwede K
Year: 2012
Journal: J Immunol
Title: Cathepsin G and neutrophil elastase contribute to lung-protective immunity against mycobacterial infections in mice.
Volume: 188
Issue: 9
Pages: 4476-87
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Publication
36016930 | J:334097
 
First Author: Zhu CL
Year: 2022
Journal: Front Immunol
Title: PD-L1 maintains neutrophil extracellular traps release by inhibiting neutrophil autophagy in endotoxin-induced lung injury.
Volume: 13
Pages: 949217
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Publication
34473230 | J:315687
First Author: Wang JF
Year: 2021
Journal: Blood
Title: Upregulated PD-L1 delays human neutrophil apoptosis and promotes lung injury in an experimental mouse model of sepsis.
Volume: 138
Issue: 9
Pages: 806-810
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Publication
21849484 | J:178402
First Author: Glenthøj A
Year: 2011
Journal: Blood
Title: Serglycin participates in retention of α-defensin in granules during myelopoiesis.
Volume: 118
Issue: 16
Pages: 4440-8
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Publication
14636558 | J:86458
First Author: Lane AA
Year: 2003
Journal: Cell
Title: Neutrophil elastase cleaves PML-RARalpha and is important for the development of acute promyelocytic leukemia in mice.
Volume: 115
Issue: 3
Pages: 305-18
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Publication
31612267 | J:282199
First Author: Liu H
Year: 2019
Journal: Diabetologia
Title: Neutrophil elastase contributes to the pathological vascular permeability characteristic of diabetic retinopathy.
Volume: 62
Issue: 12
Pages: 2365-2374
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Publication
15078883 | J:123985
First Author: Hirche TO
Year: 2004
Journal: J Biol Chem
Title: Neutrophil serine proteinases inactivate surfactant protein D by cleaving within a conserved subregion of the carbohydrate recognition domain.
Volume: 279
Issue: 26
Pages: 27688-98
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Publication
11994507 | J:76606
First Author: Allport JR
Year: 2002
Journal: J Leukoc Biol
Title: Neutrophils from MMP-9- or neutrophil elastase-deficient mice show no defect in transendothelial migration under flow in vitro.
Volume: 71
Issue: 5
Pages: 821-8
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Publication
15661916 | J:96406
First Author: Hirche TO
Year: 2005
Journal: J Immunol
Title: Myeloperoxidase plays critical roles in killing Klebsiella pneumoniae and inactivating neutrophil elastase: effects on host defense.
Volume: 174
Issue: 3
Pages: 1557-65
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Publication
25915831 | J:220590
First Author: Vicuña L
Year: 2015
Journal: Nat Med
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