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Search results 1 to 77 out of 77 for Ell3

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Hits by Pathway

Hits by Category

Hits by Strain

Type Details Score
Gene
80237 | ELL3
Type: gene
Organism: human
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Gene
100492932 | ell3
Type: gene
Organism: frog, western clawed
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Gene
296102 | Ell3
Type: gene
Organism: rat
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Gene
487526 | ELL3
Type: gene
Organism: dog, domestic
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Gene
742758 | ELL3
Type: gene
Organism: chimpanzee
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Gene
512648 | ELL3
Type: gene
Organism: cattle
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Gene
711271 | ELL3
Type: gene
Organism: macaque, rhesus
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Protein Domain
IPR031175 | ELL3
Type: Family
Description: ELL3 is a Pol II transcription elongation factor []. It binds enhancers in embryonic stem cells (ES cells), marks them, and is required for their future activation during stem cell specification []. It enhances the differentiation of mouse embryonic stem cells by protecting differentiating cells from apoptosis through the promotion of p53 degradation []. In breast cancer, Ell3 may play a critical role in promoting oncogenesis by regulating cell proliferation and cancer stem cell properties via the ERK1/2 signalling pathway [].
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Protein Coding Gene
MGI:2673679 | Ell3
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
22768269 | J:187901
First Author: Ahn HJ
Year: 2012
Journal: PLoS One
Title: Ell3 enhances differentiation of mouse embryonic stem cells by regulating epithelial-mesenchymal transition and apoptosis.
Volume: 7
Issue: 6
Pages: e40293
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Publication
23273992 | J:190435
First Author: Lin C
Year: 2013
Journal: Cell
Title: The RNA Pol II elongation factor Ell3 marks enhancers in ES cells and primes future gene activation.
Volume: 152
Issue: 1-2
Pages: 144-56
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Publication
23850691 | -
First Author: Ahn HJ
Year: 2013
Journal: Biochem Biophys Res Commun
Title: Ell3 stimulates proliferation, drug resistance, and cancer stem cell properties of breast cancer cells via a MEK/ERK-dependent signaling pathway.
Volume: 437
Issue: 4
Pages: 557-64
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Protein
Q80VR2
Organism: Mus musculus/domesticus
Length: 395  
Fragment?: false
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Publication
37591949 | J:361580
First Author: Meng S
Year: 2023
Journal: Nat Cell Biol
Title: Young LINE-1 transposon 5' UTRs marked by elongation factor ELL3 function as enhancers to regulate naïve pluripotency in embryonic stem cells.
Volume: 25
Issue: 9
Pages: 1319-1331
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Protein Coding Gene
MGP_CAROLIEiJ_G0024193 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0026392 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0026353 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0026332 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0026366 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0026112 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_2673679 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0026813 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0025574 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0026088 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0026227 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0026189 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0026328 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0026208 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0026868 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0025310 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0025643 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0025635 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0025109 | -
Type: protein_coding_gene
Organism: Mus spretus
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GXD Expression
GXD Expression
 
Probe: MGI:2023334
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1760623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824525
Age: embryonic day 14.5
Image: euxassay_007230_01
Specimen Label: euxassay_007230_01
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:2023334
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1760623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824525
Age: embryonic day 14.5
Image: euxassay_007230_02
Specimen Label: euxassay_007230_02
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:2023334
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1760623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824525
Age: embryonic day 14.5
Image: euxassay_007230_03
Specimen Label: euxassay_007230_03
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
 
Probe: MGI:2023334
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1760623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824525
Age: embryonic day 14.5
Image: euxassay_007230_04
Specimen Label: euxassay_007230_04
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
 
Probe: MGI:2023334
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1760623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824525
Age: embryonic day 14.5
Image: euxassay_007230_05
Specimen Label: euxassay_007230_05
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
 
Probe: MGI:2023334
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1760623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824525
Age: embryonic day 14.5
Image: euxassay_007230_06
Specimen Label: euxassay_007230_06
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
 
Probe: MGI:2023334
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1760623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824525
Age: embryonic day 14.5
Image: euxassay_007230_07
Specimen Label: euxassay_007230_07
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
 
Probe: MGI:2023334
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1760623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824525
Age: embryonic day 14.5
Image: euxassay_007230_08
Specimen Label: euxassay_007230_08
Detected: true
Specimen Num: 8
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GXD Expression
GXD Expression
 
Probe: MGI:2023334
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1760623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824525
Age: embryonic day 14.5
Image: euxassay_007230_09
Specimen Label: euxassay_007230_09
Detected: true
Specimen Num: 9
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GXD Expression
GXD Expression
 
Probe: MGI:2023334
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1760623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824525
Age: embryonic day 14.5
Image: euxassay_007230_10
Specimen Label: euxassay_007230_10
Detected: true
Specimen Num: 10
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GXD Expression
GXD Expression
Probe: MGI:3718622
Assay Type: RNA in situ
Annotation Date: 2007-08-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1606212
Pattern: Not Specified
Stage: TS12
Assay Id: MGI:3718656
Age: embryonic day 8.25
Image: S5-left
Note: Expression was enriched in endoderm.
Specimen Label: S5-left
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:3718622
Assay Type: RNA in situ
Annotation Date: 2007-08-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1606215
Pattern: Not Specified
Stage: TS15
Assay Id: MGI:3718656
Age: embryonic day 9.5
Image: S5-right
Specimen Label: S5-right
Detected: true
Specimen Num: 2
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Publication
- | J:85255
   
First Author: Strausberg R
Year: 2003
Journal: GenBank Submission
Title: Mus musculus, similar to hypothetical protein FLJ22637, clone MGC: 54876 IMAGE: 6313358, mRNA, complete cds
Pages: BC045151
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Publication
17328885 | J:122516
First Author: Sherwood RI
Year: 2007
Journal: Dev Biol
Title: Prospective isolation and global gene expression analysis of definitive and visceral endoderm.
Volume: 304
Issue: 2
Pages: 541-55
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Publication
- | J:81858
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: Data Curation Using Mouse Genome Assembly
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Publication
- | J:204739
     
First Author: International Knockout Mouse Consortium
Year: 2014
Journal: Database Download
Title: MGI download of modified allele data from IKMC and creation of new knockout alleles
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Publication
- | J:204812
     
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
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Publication
- | J:157065
     
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
38355793 | J:345621
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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UniProt Feature
UniProt Feature
Begin: 1
Description: RNA polymerase II elongation factor ELL3
Type: chain
End: 395
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Publication
20159561 | -
First Author: Lin C
Year: 2010
Journal: Mol Cell
Title: AFF4, a component of the ELL/P-TEFb elongation complex and a shared subunit of MLL chimeras, can link transcription elongation to leukemia.
Volume: 37
Issue: 3
Pages: 429-37
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Allele
Tg(Ell3-EGFP)OS49Gsat | MGI:4940585
Name: transgene insertion OS49, GENSAT Project at Rockefeller University
Allele Type: Transgenic
Attribute String: Reporter
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Strain
MGI:5004319 | STOCK Tg(Ell3-EGFP)OS49Gsat/Mmucd
Attribute String: mutant stock, transgenic
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Publication
- | J:100256
     
First Author: The Gene Expression Nervous System Atlas (GENSAT) Project, The Rockefeller University (New York, NY)
Year: 2005
Journal: Database Download
Title: MGI download of GENSAT transgene data
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Publication
15489334 | -
First Author: Gerhard DS
Year: 2004
Journal: Genome Res
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Volume: 14
Issue: 10B
Pages: 2121-7
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Publication
19468303 | -
First Author: Church DM
Year: 2009
Journal: PLoS Biol
Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.
Volume: 7
Issue: 5
Pages: e1000112
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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