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Search results 1 to 74 out of 74 for Ell3

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Hits by Pathway

Hits by Strain

Hits by Category

Type Details Score
Gene
80237 | ELL3
Type: gene
Organism: human
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Gene
742758 | ELL3
Type: gene
Organism: chimpanzee
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Gene
512648 | ELL3
Type: gene
Organism: cattle
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Gene
711271 | ELL3
Type: gene
Organism: macaque, rhesus
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Gene
100492932 | ell3
Type: gene
Organism: frog, western clawed
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Gene
296102 | Ell3
Type: gene
Organism: rat
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Gene
487526 | ELL3
Type: gene
Organism: dog, domestic
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Protein Domain
IPR031175 | ELL3
Type: Family
Description: ELL3 is a Pol II transcription elongation factor []. It binds enhancers in embryonic stem cells (ES cells), marks them, and is required for their future activation during stem cell specification []. It enhances the differentiation of mouse embryonic stem cells by protecting differentiating cells from apoptosis through the promotion of p53 degradation []. In breast cancer, Ell3 may play a critical role in promoting oncogenesis by regulating cell proliferation and cancer stem cell properties via the ERK1/2 signalling pathway [].
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Protein Coding Gene
MGI:2673679 | Ell3
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
22768269 | J:187901
First Author: Ahn HJ
Year: 2012
Journal: PLoS One
Title: Ell3 enhances differentiation of mouse embryonic stem cells by regulating epithelial-mesenchymal transition and apoptosis.
Volume: 7
Issue: 6
Pages: e40293
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Publication
23273992 | J:190435
First Author: Lin C
Year: 2013
Journal: Cell
Title: The RNA Pol II elongation factor Ell3 marks enhancers in ES cells and primes future gene activation.
Volume: 152
Issue: 1-2
Pages: 144-56
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Publication
23850691 | -
First Author: Ahn HJ
Year: 2013
Journal: Biochem Biophys Res Commun
Title: Ell3 stimulates proliferation, drug resistance, and cancer stem cell properties of breast cancer cells via a MEK/ERK-dependent signaling pathway.
Volume: 437
Issue: 4
Pages: 557-64
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Protein
Q80VR2
Organism: Mus musculus/domesticus
Length: 395  
Fragment?: false
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Protein Coding Gene
MGP_CAROLIEiJ_G0024193 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0026392 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0026353 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0026332 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0026366 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0026112 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_2673679 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0026813 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0025574 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0026088 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0026227 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0026189 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0026328 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0026208 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0026868 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0025310 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0025643 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0025635 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0025109 | -
Type: protein_coding_gene
Organism: Mus spretus
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GXD Expression
GXD Expression
 
Probe: MGI:2023334
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1760623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824525
Age: embryonic day 14.5
Image: euxassay_007230_01
Specimen Label: euxassay_007230_01
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:2023334
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1760623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824525
Age: embryonic day 14.5
Image: euxassay_007230_02
Specimen Label: euxassay_007230_02
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:2023334
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1760623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824525
Age: embryonic day 14.5
Image: euxassay_007230_03
Specimen Label: euxassay_007230_03
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
 
Probe: MGI:2023334
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1760623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824525
Age: embryonic day 14.5
Image: euxassay_007230_04
Specimen Label: euxassay_007230_04
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
 
Probe: MGI:2023334
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1760623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824525
Age: embryonic day 14.5
Image: euxassay_007230_05
Specimen Label: euxassay_007230_05
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
 
Probe: MGI:2023334
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1760623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824525
Age: embryonic day 14.5
Image: euxassay_007230_06
Specimen Label: euxassay_007230_06
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
 
Probe: MGI:2023334
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1760623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824525
Age: embryonic day 14.5
Image: euxassay_007230_07
Specimen Label: euxassay_007230_07
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
 
Probe: MGI:2023334
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1760623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824525
Age: embryonic day 14.5
Image: euxassay_007230_08
Specimen Label: euxassay_007230_08
Detected: true
Specimen Num: 8
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GXD Expression
GXD Expression
 
Probe: MGI:2023334
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1760623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824525
Age: embryonic day 14.5
Image: euxassay_007230_09
Specimen Label: euxassay_007230_09
Detected: true
Specimen Num: 9
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GXD Expression
GXD Expression
 
Probe: MGI:2023334
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1760623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824525
Age: embryonic day 14.5
Image: euxassay_007230_10
Specimen Label: euxassay_007230_10
Detected: true
Specimen Num: 10
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GXD Expression
GXD Expression
Probe: MGI:3718622
Assay Type: RNA in situ
Annotation Date: 2007-08-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1606212
Pattern: Not Specified
Stage: TS12
Assay Id: MGI:3718656
Age: embryonic day 8.25
Image: S5-left
Note: Expression was enriched in endoderm.
Specimen Label: S5-left
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:3718622
Assay Type: RNA in situ
Annotation Date: 2007-08-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1606215
Pattern: Not Specified
Stage: TS15
Assay Id: MGI:3718656
Age: embryonic day 9.5
Image: S5-right
Specimen Label: S5-right
Detected: true
Specimen Num: 2
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Publication
- | J:85255
   
First Author: Strausberg R
Year: 2003
Journal: GenBank Submission
Title: Mus musculus, similar to hypothetical protein FLJ22637, clone MGC: 54876 IMAGE: 6313358, mRNA, complete cds
Pages: BC045151
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Publication
17328885 | J:122516
First Author: Sherwood RI
Year: 2007
Journal: Dev Biol
Title: Prospective isolation and global gene expression analysis of definitive and visceral endoderm.
Volume: 304
Issue: 2
Pages: 541-55
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Publication
- | J:81858
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: Data Curation Using Mouse Genome Assembly
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Publication
- | J:204739
     
First Author: International Knockout Mouse Consortium
Year: 2014
Journal: Database Download
Title: MGI download of modified allele data from IKMC and creation of new knockout alleles
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Publication
- | J:204812
     
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
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Publication
- | J:157065
     
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
- | J:164563
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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UniProt Feature
UniProt Feature
Begin: 1
Description: RNA polymerase II elongation factor ELL3
Type: chain
End: 395
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Publication
20159561 | -
First Author: Lin C
Year: 2010
Journal: Mol Cell
Title: AFF4, a component of the ELL/P-TEFb elongation complex and a shared subunit of MLL chimeras, can link transcription elongation to leukemia.
Volume: 37
Issue: 3
Pages: 429-37
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Allele
Tg(Ell3-EGFP)OS49Gsat | MGI:4940585
Name: transgene insertion OS49, GENSAT Project at Rockefeller University
Allele Type: Transgenic
Attribute String: Reporter
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Strain
MGI:5004319 | STOCK Tg(Ell3-EGFP)OS49Gsat/Mmucd
Attribute String: mutant stock, transgenic
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Publication
- | J:100256
     
First Author: The Gene Expression Nervous System Atlas (GENSAT) Project, The Rockefeller University (New York, NY)
Year: 2005
Journal: Database Download
Title: MGI download of GENSAT transgene data
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Publication
15489334 | -
First Author: Gerhard DS
Year: 2004
Journal: Genome Res
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Volume: 14
Issue: 10B
Pages: 2121-7
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Publication
19468303 | -
First Author: Church DM
Year: 2009
Journal: PLoS Biol
Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.
Volume: 7
Issue: 5
Pages: e1000112
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