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Search results 1 to 100 out of 498 for Elmo1

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0.036s
Type Details Score
Gene
Type: gene
Organism: Homo sapiens
Gene
Type: gene
Organism: Rattus norvegicus
Gene
Type: gene
Organism: Danio rerio
Protein Domain
Type: Family
Description: ELMO 1-3 are orthologues of the Caenorhabditis elegans ced-12, which is required for the engulfment of dying cells and cell migration []. They are cytoplasmic adaptor proteins that interact with DOCK family guanine nucleotide exchange factors (GEFs) to promote activation of the small GTPase Rac []. ELMO proteins interact with the SH3-domain of DOCKs via an SH3-binding site to enhance the GEF activity of DOCKs. Regulatory GTPases in the Ras superfamily employ a cycle of alternating GTP binding and hydrolysis, controlled by GEFs and GTPase-activating proteins (GAPs), as essential features of their actions in cells [, ].This entry represents engulfment and cell motility protein 1 (ELMO1) from vertebrates. ELMO1 is a scaffolding component of the Elmo-Dock complex. It interacts with DOCK180, which is essential for activation of Rac GTPase-dependent biological processes. Its C-terminal pleckstrin homology (PH) domain mediates direct interaction to DOCK180 and is critical in Rac signalling []. ELMO1 also interacts with DOCK2 and plays a role in controlling DOCK2 levels and DOCK2-dependent T cell migration in primary lymphocytes [, ]. ELMO1 has been linked to invasive phenotype of cancer cells [, , ].
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Publication
First Author: Stevenson C
Year: 2014
Journal: J Immunol
Title: Essential role of Elmo1 in Dock2-dependent lymphocyte migration.
Volume: 192
Issue: 12
Pages: 6062-70
Publication
First Author: Gumienny TL
Year: 2001
Journal: Cell
Title: CED-12/ELMO, a novel member of the CrkII/Dock180/Rac pathway, is required for phagocytosis and cell migration.
Volume: 107
Issue: 1
Pages: 27-41
Gene
Type: gene
Organism: Homo sapiens
Publication
First Author: Patel A
Year: 2019
Journal: Blood Adv
Title: ELMO1 deficiency enhances platelet function.
Volume: 3
Issue: 4
Pages: 575-587
Publication
First Author: Wang J
Year: 2014
Journal: Int J Gynecol Cancer
Title: Elmo1 helps dock180 to regulate Rac1 activity and cell migration of ovarian cancer.
Volume: 24
Issue: 5
Pages: 844-50
Publication
First Author: Komander D
Year: 2008
Journal: Mol Biol Cell
Title: An alpha-helical extension of the ELMO1 pleckstrin homology domain mediates direct interaction to DOCK180 and is critical in Rac signaling.
Volume: 19
Issue: 11
Pages: 4837-51
Publication
First Author: Capala ME
Year: 2014
Journal: PLoS One
Title: ELMO1 is upregulated in AML CD34+ stem/progenitor cells, mediates chemotaxis and predicts poor prognosis in normal karyotype AML.
Volume: 9
Issue: 10
Pages: e111568
Publication
First Author: Grimsley CM
Year: 2006
Journal: J Biol Chem
Title: Characterization of a novel interaction between ELMO1 and ERM proteins.
Volume: 281
Issue: 9
Pages: 5928-37
Publication
First Author: Hathaway CK
Year: 2016
Journal: Proc Natl Acad Sci U S A
Title: High Elmo1 expression aggravates and low Elmo1 expression prevents diabetic nephropathy.
Volume: 113
Issue: 8
Pages: 2218-22
Publication  
First Author: Katoh H
Year: 2006
Journal: Brain Res
Title: Differential distribution of ELMO1 and ELMO2 mRNAs in the developing mouse brain.
Volume: 1073-1074
Pages: 103-8
Publication
First Author: Elliott MR
Year: 2010
Journal: Nature
Title: Unexpected requirement for ELMO1 in clearance of apoptotic germ cells in vivo.
Volume: 467
Issue: 7313
Pages: 333-7
Publication
First Author: Arandjelovic S
Year: 2019
Journal: Nat Immunol
Title: A noncanonical role for the engulfment gene ELMO1 in neutrophils that promotes inflammatory arthritis.
Volume: 20
Issue: 2
Pages: 141-151
Publication
First Author: Mauldin JP
Year: 2013
Journal: Curr Biol
Title: A link between the cytoplasmic engulfment protein Elmo1 and the Mediator complex subunit Med31.
Volume: 23
Issue: 2
Pages: 162-7
Publication  
First Author: Li H
Year: 2013
Journal: Nat Commun
Title: Association between Gαi2 and ELMO1/Dock180 connects chemokine signalling with Rac activation and metastasis.
Volume: 4
Pages: 1706
GXD Expression
Probe: MGI:6384815
Assay Type: RNA in situ
Annotation Date: 2020-01-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:3558828
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:6384837
Age: postnatal day 21
Image: 6B Elmo1
Note: Moderately high expression at boundary between cortical layer VI and underlying white matter, and in cells of laver IV.
Detected: true
Specimen Num: 22
GXD Expression  
Probe: MGI:6384815
Assay Type: RNA in situ
Annotation Date: 2020-01-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1903728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6384837
Age: postnatal day 7
Image: 8A Elmo1
Detected: true
Specimen Num: 28
GXD Expression  
Probe: MGI:6384815
Assay Type: RNA in situ
Annotation Date: 2020-01-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1778728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6384837
Age: postnatal day 7
Image: 3A Elmo1
Detected: true
Specimen Num: 4
GXD Expression  
Probe: MGI:6384815
Assay Type: RNA in situ
Annotation Date: 2020-01-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1778728
Pattern: Scattered
Stage: TS28
Assay Id: MGI:6384837
Age: postnatal day 21
Image: 9B Elmo1
Detected: true
Specimen Num: 32
GXD Expression  
Probe: MGI:6384815
Assay Type: RNA in situ
Annotation Date: 2020-01-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1754428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6384837
Age: postnatal day 7
Image: 3A Elmo1
Detected: true
Specimen Num: 4
GXD Expression  
Probe: MGI:6384815
Assay Type: RNA in situ
Annotation Date: 2020-01-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3284528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6384837
Age: postnatal day 7
Image: 3A Elmo1
Detected: true
Specimen Num: 4
GXD Expression  
Probe: MGI:6384815
Assay Type: RNA in situ
Annotation Date: 2020-01-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3284528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6384837
Age: postnatal day 7
Image: 7A Elmo1
Detected: true
Specimen Num: 23
GXD Expression  
Probe: MGI:6384815
Assay Type: RNA in situ
Annotation Date: 2020-01-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3284528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6384837
Age: postnatal day 7
Image: 8A Elmo1
Detected: true
Specimen Num: 28
GXD Expression  
Probe: MGI:6384815
Assay Type: RNA in situ
Annotation Date: 2020-01-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3569228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6384837
Age: postnatal day 7
Image: 3A Elmo1
Detected: true
Specimen Num: 4
GXD Expression  
Probe: MGI:6384815
Assay Type: RNA in situ
Annotation Date: 2020-01-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1754028
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6384837
Age: postnatal day 7
Image: 3A Elmo1
Detected: true
Specimen Num: 4
GXD Expression  
Probe: MGI:6384815
Assay Type: RNA in situ
Annotation Date: 2020-01-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3280928
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6384837
Age: postnatal day 7
Image: 3A Elmo1
Detected: true
Specimen Num: 4
GXD Expression
Probe: MGI:6384815
Assay Type: RNA in situ
Annotation Date: 2020-01-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:6384837
Age: postnatal day 21
Image: 5B Elmo1
Note: Authors report regional expression patterns roughly similar to those in B6 mouse brains.
Detected: true
Specimen Num: 18
Publication    
First Author: McCauley HA
Year: 2017
Journal: Elife
Title: De-repression of the RAC activator ELMO1 in cancer stem cells drives progression of TGFβ-deficient squamous cell carcinoma from transition zones.
Volume: 6
Protein
Organism: Mus musculus
Length: 193  
Fragment?: true
Publication
First Author: Sanui T
Year: 2003
Journal: Blood
Title: DOCK2 regulates Rac activation and cytoskeletal reorganization through interaction with ELMO1.
Volume: 102
Issue: 8
Pages: 2948-50
Protein
Organism: Mus musculus
Length: 727  
Fragment?: false
Protein
Organism: Mus musculus
Length: 741  
Fragment?: true
Publication
First Author: Bowzard JB
Year: 2007
Journal: J Biol Chem
Title: ELMOD2 is an Arl2 GTPase-activating protein that also acts on Arfs.
Volume: 282
Issue: 24
Pages: 17568-80
GXD Expression
Probe: MGI:6384815
Assay Type: RNA in situ
Annotation Date: 2020-01-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:3558828
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:6384837
Age: postnatal day 21
Image: 5A Elmo1 (3rd row)
Note: Moderately high expression in cells around lover layers IV-VI.
Detected: true
Specimen Num: 16
GXD Expression
Probe: MGI:6384815
Assay Type: RNA in situ
Annotation Date: 2020-01-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3538028
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6384837
Age: postnatal day 21
Image: 5A Elmo1 (2nd row)
Note: Expression in caudate putamen, nucleus accumbens and globus pallidus slightly higher than that of Elmo2 and Elmo3.
Detected: true
Specimen Num: 15
GXD Expression
Probe: MGI:6384815
Assay Type: RNA in situ
Annotation Date: 2020-01-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1909528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6384837
Age: postnatal day 21
Image: 4A Elmo1 WT
Note: Expression in caudate putamen, nucleus accumbens and globus pallidus slightly higher than that of Elmo2 and Elmo3.
Detected: true
Specimen Num: 10
GXD Expression  
Probe: MGI:6384815
Assay Type: RNA in situ
Annotation Date: 2020-01-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3276728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6384837
Age: postnatal day 7
Image: 3B Elmo1 (middle)
Detected: true
Specimen Num: 6
GXD Expression  
Probe: MGI:6384815
Assay Type: RNA in situ
Annotation Date: 2020-01-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3286928
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6384837
Age: postnatal day 7
Image: 3C Elmo1 (left)
Detected: true
Specimen Num: 8
GXD Expression
Probe: MGI:6384815
Assay Type: RNA in situ
Annotation Date: 2020-01-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1778725
Pattern: Regionally restricted
Stage: TS25
Assay Id: MGI:6384837
Age: embryonic day 17.0
Image: 9C Elmo1 rl
Note: Expressing cells around Purkinje cell plate and deep cerebellar nucleus abberrantly localized in reeler cerebellum.
Detected: true
Specimen Num: 34
GXD Expression  
Probe: MGI:6384815
Assay Type: RNA in situ
Annotation Date: 2020-01-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1778728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6384837
Age: postnatal day 7
Image: 9A Elmo1 P7
Detected: true
Specimen Num: 30
GXD Expression
Probe: MGI:6384815
Assay Type: RNA in situ
Annotation Date: 2020-01-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754425
Pattern: Regionally restricted
Stage: TS25
Assay Id: MGI:6384837
Age: embryonic day 17.0
Image: 2A Elmo1 rl
Note: Authors report layer-dependent expression seemed affected at E17.
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:6384815
Assay Type: RNA in situ
Annotation Date: 2020-01-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754425
Pattern: Not Specified
Stage: TS25
Assay Id: MGI:6384837
Age: embryonic day 17.0
Image: 6A Elmo1 + Elmo3
Detected: true
Specimen Num: 21
GXD Expression
Probe: MGI:6384815
Assay Type: RNA in situ
Annotation Date: 2020-01-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3522128
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6384837
Age: postnatal day 21
Image: 10A Elmo1 P21
Note: Expression in Purkinje cell layers. Expression localized in cells of molecular layer and a few large cells of the internal granular layer.
Detected: true
Specimen Num: 36
GXD Expression  
Probe: MGI:6384815
Assay Type: RNA in situ
Annotation Date: 2020-01-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3267228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6384837
Age: postnatal day 21
Image: 5A Elmo1 (3rd row)
Detected: true
Specimen Num: 16
GXD Expression  
Probe: MGI:6384815
Assay Type: RNA in situ
Annotation Date: 2020-01-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3284528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6384837
Age: postnatal day 21
Image: 7C Elmo1 B6
Detected: true
Specimen Num: 26
GXD Expression  
Probe: MGI:6384815
Assay Type: RNA in situ
Annotation Date: 2020-01-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3284528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6384837
Age: postnatal day 7
Image: 8A Elmo1 + GAD
Detected: true
Specimen Num: 29
GXD Expression  
Probe: MGI:6384815
Assay Type: RNA in situ
Annotation Date: 2020-01-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3535728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6384837
Age: postnatal day 7
Image: 3B Elmo1 (upper)
Detected: true
Specimen Num: 5
GXD Expression  
Probe: MGI:6384815
Assay Type: RNA in situ
Annotation Date: 2020-01-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1691325
Pattern: Not Specified
Stage: TS25
Assay Id: MGI:6384837
Age: embryonic day 17.0
Image: 2A Elmo1 B6
Detected: true
Specimen Num: 1
GXD Expression
Probe: MGI:6384815
Assay Type: RNA in situ
Annotation Date: 2020-01-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3522328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6384837
Age: postnatal day 7
Image: 10A Elmo1 P7
Note: Expression localized predominantly in inner external granular layer, Purkinje cell layer, and intermediately in internal granular cells layer.
Detected: true
Specimen Num: 35
GXD Expression
Probe: MGI:6384815
Assay Type: RNA in situ
Annotation Date: 2020-01-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3521628
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6384837
Age: postnatal day 7
Image: 10A Elmo1 P7
Note: Expression localized predominantly in inner external granular layer, Purkinje cell layer, and intermediately in internal granular cells layer.
Detected: true
Specimen Num: 35
GXD Expression  
Probe: MGI:6384815
Assay Type: RNA in situ
Annotation Date: 2020-01-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1754025
Pattern: Not Specified
Stage: TS25
Assay Id: MGI:6384837
Age: embryonic day 17.0
Image: 2A Elmo1 B6
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:6384815
Assay Type: RNA in situ
Annotation Date: 2020-01-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754025
Pattern: Not Specified
Stage: TS25
Assay Id: MGI:6384837
Age: embryonic day 17.0
Image: 6A Elmo1 + Elmo3
Detected: true
Specimen Num: 21
GXD Expression
Probe: MGI:6384815
Assay Type: RNA in situ
Annotation Date: 2020-01-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689425
Pattern: Regionally restricted
Stage: TS25
Assay Id: MGI:6384837
Age: embryonic day 17.0
Image: 2A Elmo1 rl
Note: Authors report overall expression not severely affect by the mutation.
Detected: true
Specimen Num: 2
GXD Expression
Probe: MGI:6384815
Assay Type: RNA in situ
Annotation Date: 2020-01-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:3558828
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:6384837
Age: postnatal day 21
Image: 5A Elmo1 (1st row)
Note: Moderately high expression in cells around lover layers IV-VI.
Detected: true
Specimen Num: 14
GXD Expression  
Probe: MGI:6384815
Assay Type: RNA in situ
Annotation Date: 2020-01-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3529728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6384837
Age: postnatal day 21
Image: 5A Elmo1 (4th row)
Detected: true
Specimen Num: 17
GXD Expression
Probe: MGI:6384815
Assay Type: RNA in situ
Annotation Date: 2020-01-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3538028
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6384837
Age: postnatal day 21
Image: 4A Elmo1 WT
Note: Expression in caudate putamen, nucleus accumbens and globus pallidus slightly higher than that of Elmo2 and Elmo3.
Detected: true
Specimen Num: 10
GXD Expression  
Probe: MGI:6384815
Assay Type: RNA in situ
Annotation Date: 2020-01-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1754925
Pattern: Not Specified
Stage: TS25
Assay Id: MGI:6384837
Age: embryonic day 17.0
Image: 2A Elmo1 B6
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:6384815
Assay Type: RNA in situ
Annotation Date: 2020-01-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754928
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6384837
Age: postnatal day 7
Image: 3B Elmo1 (middle)
Detected: true
Specimen Num: 6
GXD Expression  
Probe: MGI:6384815
Assay Type: RNA in situ
Annotation Date: 2020-01-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1697425
Pattern: Not Specified
Stage: TS25
Assay Id: MGI:6384837
Age: embryonic day 17.0
Image: 2A Elmo1 B6
Detected: true
Specimen Num: 1
GXD Expression
Probe: MGI:6384815
Assay Type: RNA in situ
Annotation Date: 2020-01-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3521928
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6384837
Age: postnatal day 21
Image: 10A Elmo1 P21
Note: Expression in Purkinje cell layers. Expression localized in cells of molecular layer and a few large cells of the internal granular layer.
Detected: true
Specimen Num: 36
GXD Expression
Probe: MGI:6384815
Assay Type: RNA in situ
Annotation Date: 2020-01-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3521928
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6384837
Age: postnatal day 7
Image: 10A Elmo1 P7
Note: Expression localized predominantly in inner external granular layer, Purkinje cell layer, and intermediately in internal granular cells layer.
Detected: true
Specimen Num: 35
GXD Expression
Probe: MGI:6384815
Assay Type: RNA in situ
Annotation Date: 2020-01-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3521928
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:6384837
Age: postnatal day 21
Image: 10B Elmo1 + GAD
Note: Expression in Gad1-expressing cerebellar neurons, namely in Purkinje cells of Purkinje cell layer, stellate cells and basket cells of molecular layer, and Golgi cells of internal granular layer.
Detected: true
Specimen Num: 37
GXD Expression
Probe: MGI:6384815
Assay Type: RNA in situ
Annotation Date: 2020-01-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1903728
Pattern: Scattered
Stage: TS28
Assay Id: MGI:6384837
Age: postnatal day 7
Image: 8A Elmo1 + GAD
Note: Authors report expression in some Gad1-expressing interneurons scattered in the hippocampus.
Detected: true
Specimen Num: 29
GXD Expression  
Probe: MGI:6384815
Assay Type: RNA in situ
Annotation Date: 2020-01-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1755025
Pattern: Not Specified
Stage: TS25
Assay Id: MGI:6384837
Age: embryonic day 17.0
Image: 2A Elmo1 B6
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:6384815
Assay Type: RNA in situ
Annotation Date: 2020-01-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1755028
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6384837
Age: postnatal day 7
Image: 3B Elmo1 (lower)
Detected: true
Specimen Num: 7
GXD Expression
Probe: MGI:6384815
Assay Type: RNA in situ
Annotation Date: 2020-01-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1909528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6384837
Age: postnatal day 21
Image: 5A Elmo1 (2nd row)
Note: Expression in caudate putamen, nucleus accumbens and globus pallidus slightly higher than that of Elmo2 and Elmo3.
Detected: true
Specimen Num: 15
GXD Expression
Probe: MGI:6384815
Assay Type: RNA in situ
Annotation Date: 2020-01-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3276728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6384837
Age: postnatal day 21
Image: 5A Elmo1 (4th row)
Note: High expression in piriform cortex in vicinity of intermediate-high expression in cells of lateral olfactory tract and olfactory tubercle.
Detected: true
Specimen Num: 17
GXD Expression  
Probe: MGI:6384815
Assay Type: RNA in situ
Annotation Date: 2020-01-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1753625
Pattern: Not Specified
Stage: TS25
Assay Id: MGI:6384837
Age: embryonic day 17.0
Image: 2A Elmo1 B6
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:6384815
Assay Type: RNA in situ
Annotation Date: 2020-01-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3547928
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6384837
Age: postnatal day 21
Image: 5A Elmo1 (4th row)
Detected: true
Specimen Num: 17
GXD Expression  
Probe: MGI:6384815
Assay Type: RNA in situ
Annotation Date: 2020-01-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1778725
Pattern: Not Specified
Stage: TS25
Assay Id: MGI:6384837
Age: embryonic day 17.0
Image: 2A Elmo1 B6
Detected: true
Specimen Num: 1
GXD Expression
Probe: MGI:6384815
Assay Type: RNA in situ
Annotation Date: 2020-01-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1778725
Pattern: Regionally restricted
Stage: TS25
Assay Id: MGI:6384837
Age: embryonic day 17.0
Image: 9C Elmo1 B6
Note: Expressing cells around Purkinje cell plate and deep cerebellar nucleus.
Detected: true
Specimen Num: 33
GXD Expression  
Probe: MGI:6384815
Assay Type: RNA in situ
Annotation Date: 2020-01-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1778728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6384837
Age: postnatal day 7
Image: 3B Elmo1 (lower)
Detected: true
Specimen Num: 7
GXD Expression  
Probe: MGI:6384815
Assay Type: RNA in situ
Annotation Date: 2020-01-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1778728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6384837
Age: postnatal day 21
Image: 9A Elmo1 P21
Detected: true
Specimen Num: 31
GXD Expression  
Probe: MGI:6384815
Assay Type: RNA in situ
Annotation Date: 2020-01-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1754425
Pattern: Not Specified
Stage: TS25
Assay Id: MGI:6384837
Age: embryonic day 17.0
Image: 2A Elmo1 B6
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:6384815
Assay Type: RNA in situ
Annotation Date: 2020-01-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754425
Pattern: Not Specified
Stage: TS25
Assay Id: MGI:6384837
Age: embryonic day 17.0
Image: 6A Reelin + Elmo1
Detected: true
Specimen Num: 19
GXD Expression  
Probe: MGI:6384815
Assay Type: RNA in situ
Annotation Date: 2020-01-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754425
Pattern: Not Specified
Stage: TS25
Assay Id: MGI:6384837
Age: embryonic day 17.0
Image: 6A Elmo1 + Elmo2
Detected: true
Specimen Num: 20
GXD Expression
Probe: MGI:6384815
Assay Type: RNA in situ
Annotation Date: 2020-01-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754428
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:6384837
Age: postnatal day 7
Image: 3C Elmo1 (left)
Note: Moderately high expression at boundary between cortical layer VI and underlying white matter, and in cells of laver IV.
Detected: true
Specimen Num: 8
GXD Expression
Probe: MGI:6384815
Assay Type: RNA in situ
Annotation Date: 2020-01-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3522128
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:6384837
Age: postnatal day 21
Image: 10B Elmo1 + GAD
Note: Expression in Gad1-expressing cerebellar neurons, namely in Purkinje cells of Purkinje cell layer, stellate cells and basket cells of molecular layer, and Golgi cells of internal granular layer.
Detected: true
Specimen Num: 37
GXD Expression
Probe: MGI:6384815
Assay Type: RNA in situ
Annotation Date: 2020-01-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3278928
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6384837
Age: postnatal day 21
Image: 4A Elmo1 WT
Note: Expression in caudate putamen, nucleus accumbens and globus pallidus slightly higher than that of Elmo2 and Elmo3.
Detected: true
Specimen Num: 10
GXD Expression
Probe: MGI:6384815
Assay Type: RNA in situ
Annotation Date: 2020-01-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3278928
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6384837
Age: postnatal day 21
Image: 5A Elmo1 (2nd row)
Note: Expression in caudate putamen, nucleus accumbens and globus pallidus slightly higher than that of Elmo2 and Elmo3.
Detected: true
Specimen Num: 15
GXD Expression  
Probe: MGI:6384815
Assay Type: RNA in situ
Annotation Date: 2020-01-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:3284525
Pattern: Not Specified
Stage: TS25
Assay Id: MGI:6384837
Age: embryonic day 17.0
Image: 2A Elmo1 B6
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:6384815
Assay Type: RNA in situ
Annotation Date: 2020-01-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3284528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6384837
Age: postnatal day 7
Image: 3C Elmo1 (left)
Detected: true
Specimen Num: 8
GXD Expression  
Probe: MGI:6384815
Assay Type: RNA in situ
Annotation Date: 2020-01-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3284528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6384837
Age: postnatal day 21
Image: 5A Elmo1 (3rd row)
Detected: true
Specimen Num: 16
GXD Expression  
Probe: MGI:6384815
Assay Type: RNA in situ
Annotation Date: 2020-01-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3284528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6384837
Age: postnatal day 21
Image: 7B Elmo1 B6
Detected: true
Specimen Num: 24
GXD Expression    
Probe: MGI:6384815
Assay Type: RNA in situ
Annotation Date: 2020-01-14
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:3284528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6384837
Age: postnatal day 21
Image: 7B Elmo1 rl
Specimen Num: 25
GXD Expression    
Probe: MGI:6384815
Assay Type: RNA in situ
Annotation Date: 2020-01-14
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:3284528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6384837
Age: postnatal day 21
Image: 7C Elmo1 rl
Specimen Num: 27
GXD Expression  
Probe: MGI:6384815
Assay Type: RNA in situ
Annotation Date: 2020-01-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3513128
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6384837
Age: postnatal day 7
Image: 3B Elmo1 (upper)
Detected: true
Specimen Num: 5
GXD Expression
Probe: MGI:6384815
Assay Type: RNA in situ
Annotation Date: 2020-01-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3522328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6384837
Age: postnatal day 21
Image: 10A Elmo1 P21
Note: Expression in Purkinje cell layers. Expression localized in cells of molecular layer and a few large cells of the internal granular layer.
Detected: true
Specimen Num: 36
GXD Expression
Probe: MGI:6384815
Assay Type: RNA in situ
Annotation Date: 2020-01-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3522328
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:6384837
Age: postnatal day 21
Image: 10B Elmo1 + GAD
Note: Expression in Gad1-expressing cerebellar neurons, namely in Purkinje cells of Purkinje cell layer, stellate cells and basket cells of molecular layer, and Golgi cells of internal granular layer.
Detected: true
Specimen Num: 37
GXD Expression  
Probe: MGI:6384815
Assay Type: RNA in situ
Annotation Date: 2020-01-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754025
Pattern: Not Specified
Stage: TS25
Assay Id: MGI:6384837
Age: embryonic day 17.0
Image: 6A Reelin + Elmo1
Detected: true
Specimen Num: 19
GXD Expression  
Probe: MGI:6384815
Assay Type: RNA in situ
Annotation Date: 2020-01-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754025
Pattern: Not Specified
Stage: TS25
Assay Id: MGI:6384837
Age: embryonic day 17.0
Image: 6A Elmo1 + Elmo2
Detected: true
Specimen Num: 20
GXD Expression  
Probe: MGI:6384815
Assay Type: RNA in situ
Annotation Date: 2020-01-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3280925
Pattern: Not Specified
Stage: TS25
Assay Id: MGI:6384837
Age: embryonic day 17.0
Image: 2A Elmo1 B6
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:6384815
Assay Type: RNA in situ
Annotation Date: 2020-01-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3280928
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6384837
Age: postnatal day 7
Image: 3B Elmo1 (upper)
Detected: true
Specimen Num: 5
GXD Expression  
Probe: MGI:6384815
Assay Type: RNA in situ
Annotation Date: 2020-01-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1756325
Pattern: Not Specified
Stage: TS25
Assay Id: MGI:6384837
Age: embryonic day 17.0
Image: 2A Elmo1 B6
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:6384815
Assay Type: RNA in situ
Annotation Date: 2020-01-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3554428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6384837
Age: postnatal day 7
Image: 3C Elmo1 (left)
Detected: true
Specimen Num: 8
GXD Expression
Probe: MGI:6384815
Assay Type: RNA in situ
Annotation Date: 2020-01-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1689425
Pattern: Regionally restricted
Stage: TS25
Assay Id: MGI:6384837
Age: embryonic day 17.0
Image: 2B Reelin + Elmo1
Note: Authors report high expression in superficial regions of the brain with intense Reln expression.
Detected: true
Specimen Num: 3