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Search results 1 to 100 out of 329 for Elmo2

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Type Details Score
Gene
63916 | ELMO2
Type: gene
Organism: human
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Gene
458299 | ELMO2
Type: gene
Organism: chimpanzee
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Gene
508361 | ELMO2
Type: gene
Organism: cattle
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Gene
419307 | ELMO2
Type: gene
Organism: chicken
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Gene
100006857 | elmo2
Type: gene
Organism: zebrafish
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Gene
707316 | ELMO2
Type: gene
Organism: macaque, rhesus
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Gene
493485 | elmo2
Type: gene
Organism: frog, western clawed
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Gene
119865677 | ELMO2
Type: gene
Organism: dog, domestic
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Gene
362271 | Elmo2
Type: gene
Organism: rat
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Protein Domain
IPR030713 | ELMO2
Type: Family
Description: This entry represents engulfment and cell motility protein 2 (ELMO2) from vertebrates. ELMO2 is a scaffolding component of the Elmo-DOCK complex. Elmo2 and DOCK1 are essential for the rapid recruitment and spreading of E-cadherin, actin reorganisation, localised Rac and Rho GTPase activities, and the development of strong cell-cell adhesion []. ELMO2 interacts with Axl, a receptor tyrosine kinase, and this interaction contributes to cancer cell invasion and proliferation [].ELMO 1-3 are orthologues of the Caenorhabditis elegans ced-12, which is required for the engulfment of dying cells and cell migration []. They are cytoplasmic adaptor proteins that interact with DOCK family guanine nucleotide exchange factors (GEFs) to promote activation of the small GTPase Rac []. ELMO proteins interact with the SH3-domain of DOCKs via an SH3-binding site to enhance the GEF activity of DOCKs. Regulatory GTPases in the Ras superfamily employ a cycle of alternating GTP binding and hydrolysis, controlled by GEFs and GTPase-activating proteins (GAPs), as essential features of their actions in cells [, ].
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Protein Coding Gene
MGI:2153045 | Elmo2
Type: protein_coding_gene
Organism: mouse, laboratory
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GXD Expression
GXD Expression
Probe: MGI:6384816
Assay Type: RNA in situ
Annotation Date: 2020-01-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3267228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6384838
Age: postnatal day 21
Image: 5B Elmo2
Note: In amygdala, espression of Elmo2 more affected than that of Elmo1 and Elmo3.
Specimen Label: 5B Elmo2
Detected: true
Specimen Num: 17
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Publication
11595183 | J:72091
First Author: Gumienny TL
Year: 2001
Journal: Cell
Title: CED-12/ELMO, a novel member of the CrkII/Dock180/Rac pathway, is required for phagocytosis and cell migration.
Volume: 107
Issue: 1
Pages: 27-41
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GXD Expression
GXD Expression
Probe: MGI:6384816
Assay Type: RNA in situ
Annotation Date: 2020-01-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3267228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6384838
Age: postnatal day 21
Image: 5D Elmo2 rl
Note: In amygdala, espression of Elmo2 more affected than that of Elmo1 and Elmo3.
Specimen Label: 5D Elmo2 rl
Detected: true
Specimen Num: 19
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GXD Expression
GXD Expression
Probe: MGI:6384816
Assay Type: RNA in situ
Annotation Date: 2020-01-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1903728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6384838
Age: postnatal day 7
Image: 7A Elmo2
Note: Characteristic pattern of expression in dentate gyrus.
Specimen Label: 7A Elmo2
Detected: true
Specimen Num: 25
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GXD Expression
GXD Expression
 
Probe: MGI:6384816
Assay Type: RNA in situ
Annotation Date: 2020-01-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3284528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6384838
Age: postnatal day 7
Image: 7A Elmo2
Specimen Label: 7A Elmo2
Detected: true
Specimen Num: 25
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GXD Expression
GXD Expression
 
Probe: MGI:6384816
Assay Type: RNA in situ
Annotation Date: 2020-01-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3287028
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6384838
Age: postnatal day 7
Image: 3A Elmo2
Specimen Label: 3A Elmo2
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
 
Probe: MGI:6384816
Assay Type: RNA in situ
Annotation Date: 2020-01-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3527628
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6384838
Age: postnatal day 7
Image: 8B Elmo2
Specimen Label: 8B Elmo2
Detected: true
Specimen Num: 30
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GXD Expression
GXD Expression
 
Probe: MGI:6384816
Assay Type: RNA in situ
Annotation Date: 2020-01-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3807528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6384838
Age: postnatal day 7
Image: 3A Elmo2
Specimen Label: 3A Elmo2
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
Probe: MGI:6384816
Assay Type: RNA in situ
Annotation Date: 2020-01-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1778728
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:6384838
Age: postnatal day 21
Image: 9B Elmo2
Note: Expressing cells localized around outer rim area of cerebellum.
Specimen Label: 9B Elmo2
Detected: true
Specimen Num: 36
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GXD Expression
GXD Expression
 
Probe: MGI:6384816
Assay Type: RNA in situ
Annotation Date: 2020-01-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1778728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6384838
Age: postnatal day 7
Image: 3A Elmo2
Specimen Label: 3A Elmo2
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
 
Probe: MGI:6384816
Assay Type: RNA in situ
Annotation Date: 2020-01-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3284528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6384838
Age: postnatal day 7
Image: 3A Elmo2
Specimen Label: 3A Elmo2
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
 
Probe: MGI:6384816
Assay Type: RNA in situ
Annotation Date: 2020-01-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3280928
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6384838
Age: postnatal day 7
Image: 3A Elmo2
Specimen Label: 3A Elmo2
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
Probe: MGI:6384816
Assay Type: RNA in situ
Annotation Date: 2020-01-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3558828
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:6384838
Age: postnatal day 21
Image: 6B Elmo2 (left)
Note: Higher expression in cells around layer II/III.
Specimen Label: 6B Elmo2 (left)
Detected: true
Specimen Num: 21
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GXD Expression
GXD Expression
 
Probe: MGI:6384816
Assay Type: RNA in situ
Annotation Date: 2020-01-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3521928
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6384838
Age: postnatal day 7
Image: 10A Elmo2 P7
Specimen Label: 10A Elmo2 P7
Detected: true
Specimen Num: 37
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GXD Expression
GXD Expression
Probe: MGI:6384816
Assay Type: RNA in situ
Annotation Date: 2020-01-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1903728
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:6384838
Age: postnatal day 7
Image: 8B Elmo2 inset
Note: Higher expression distributed unevenly in superficial area of granule cell layer (side of marginal zone between granule cell layer and molecular layer) than in cells in deeper layer (near subgranular zone).
Specimen Label: 8B Elmo2 inset
Detected: true
Specimen Num: 31
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GXD Expression
GXD Expression
 
Probe: MGI:6384816
Assay Type: RNA in situ
Annotation Date: 2020-01-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3276728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6384838
Age: postnatal day 7
Image: 3B Elmo2 (middle)
Specimen Label: 3B Elmo2 (middle)
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
Probe: MGI:6384816
Assay Type: RNA in situ
Annotation Date: 2020-01-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3522128
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:6384838
Age: postnatal day 21
Image: 10A Elmo2 P21
Note: Expression in basket cells of molecular layer.
Specimen Label: 10A Elmo2 P21
Detected: true
Specimen Num: 38
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GXD Expression
GXD Expression
Probe: MGI:6384816
Assay Type: RNA in situ
Annotation Date: 2020-01-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3548828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6384838
Age: postnatal day 7
Image: 3B Elmo2 (upper)
Note: Expression in ventricular zone or surrounding lateral ventricles.
Specimen Label: 3B Elmo2 (upper)
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
Probe: MGI:6384816
Assay Type: RNA in situ
Annotation Date: 2020-01-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3284528
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:6384838
Age: postnatal day 21
Image: 5A Elmo2 (3rd row)
Note: High expression in hippocampus. Higher expression in cells around layer II/III.
Specimen Label: 5A Elmo2 (3rd row)
Detected: true
Specimen Num: 15
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GXD Expression
GXD Expression
 
Probe: MGI:6384816
Assay Type: RNA in situ
Annotation Date: 2020-01-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3284528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6384838
Age: postnatal day 21
Image: 7C Elmo2 rl
Specimen Label: 7C Elmo2 rl
Detected: true
Specimen Num: 29
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GXD Expression
GXD Expression
 
Probe: MGI:6384816
Assay Type: RNA in situ
Annotation Date: 2020-01-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3554728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6384838
Age: postnatal day 21
Image: 5A Elmo2 (4th row)
Specimen Label: 5A Elmo2 (4th row)
Detected: true
Specimen Num: 16
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GXD Expression
GXD Expression
Probe: MGI:6384816
Assay Type: RNA in situ
Annotation Date: 2020-01-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3535728
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:6384838
Age: postnatal day 21
Image: 6B Elmo2 + Calbindin
Note: Majority of expression cells in upper layer of frontal cortex were Calb1-expressing cells of layer II/III.
Specimen Label: 6B Elmo2 + Calbindin
Detected: true
Specimen Num: 22
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GXD Expression
GXD Expression
 
Probe: MGI:6384816
Assay Type: RNA in situ
Annotation Date: 2020-01-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3527628
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6384838
Age: postnatal day 21
Image: 7B Elmo2 B6
Specimen Label: 7B Elmo2 B6
Detected: true
Specimen Num: 26
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GXD Expression
GXD Expression
 
Probe: MGI:6384816
Assay Type: RNA in situ
Annotation Date: 2020-01-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3566728
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:6384838
Age: postnatal day 21
Image: 6C Elmo2 B6
Specimen Label: 6C Elmo2 B6
Detected: true
Specimen Num: 23
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GXD Expression
GXD Expression
 
Probe: MGI:6384816
Assay Type: RNA in situ
Annotation Date: 2020-01-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3529728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6384838
Age: postnatal day 21
Image: 5A Elmo2 (4th row)
Specimen Label: 5A Elmo2 (4th row)
Detected: true
Specimen Num: 16
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GXD Expression
GXD Expression
Probe: MGI:6384816
Assay Type: RNA in situ
Annotation Date: 2020-01-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1903725
Pattern: Regionally restricted
Stage: TS25
Assay Id: MGI:6384838
Age: embryonic day 17.0
Image: 2A Elmo2 B6
Note: Expression in dentate gyrus granule cells higher than that of Elmo1 and Elmo3.
Specimen Label: 2A Elmo2 B6
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:6384816
Assay Type: RNA in situ
Annotation Date: 2020-01-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1903728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6384838
Age: postnatal day 7
Image: 3B Elmo2 (middle)
Specimen Label: 3B Elmo2 (middle)
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
 
Probe: MGI:6384816
Assay Type: RNA in situ
Annotation Date: 2020-01-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1903728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6384838
Age: postnatal day 21
Image: 7B Elmo2 rl
Specimen Label: 7B Elmo2 rl
Detected: true
Specimen Num: 27
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GXD Expression
GXD Expression
 
Probe: MGI:6384816
Assay Type: RNA in situ
Annotation Date: 2020-01-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1903728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6384838
Age: postnatal day 21
Image: 7C Elmo2 rl
Specimen Label: 7C Elmo2 rl
Detected: true
Specimen Num: 29
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GXD Expression
GXD Expression
 
Probe: MGI:6384816
Assay Type: RNA in situ
Annotation Date: 2020-01-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1903728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6384838
Age: postnatal day 21
Image: 8C Elmo2 coronal
Specimen Label: 8C Elmo2 coronal
Detected: true
Specimen Num: 33
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GXD Expression
GXD Expression
Probe: MGI:6384816
Assay Type: RNA in situ
Annotation Date: 2020-01-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3276728
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:6384838
Age: postnatal day 21
Image: 5A Elmo2 (4th row)
Note: High expression in piriform cortex in vicinity of intermediate-high expression in cells of lateral olfactory tract and olfactory tubercle.
Specimen Label: 5A Elmo2 (4th row)
Detected: true
Specimen Num: 16
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GXD Expression
GXD Expression
 
Probe: MGI:6384816
Assay Type: RNA in situ
Annotation Date: 2020-01-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3276828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6384838
Age: postnatal day 21
Image: 7B Elmo2 B6
Specimen Label: 7B Elmo2 B6
Detected: true
Specimen Num: 26
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GXD Expression
GXD Expression
 
Probe: MGI:6384816
Assay Type: RNA in situ
Annotation Date: 2020-01-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3276828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6384838
Age: postnatal day 21
Image: 7C Elmo2 B6
Specimen Label: 7C Elmo2 B6
Detected: true
Specimen Num: 28
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GXD Expression
GXD Expression
 
Probe: MGI:6384816
Assay Type: RNA in situ
Annotation Date: 2020-01-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1778728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6384838
Age: postnatal day 7
Image: 3B Elmo2 (lower)
Specimen Label: 3B Elmo2 (lower)
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
 
Probe: MGI:6384816
Assay Type: RNA in situ
Annotation Date: 2020-01-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1778728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6384838
Age: postnatal day 7
Image: 3C Elmo2 (right)
Specimen Label: 3C Elmo2 (right)
Detected: true
Specimen Num: 8
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GXD Expression
GXD Expression
 
Probe: MGI:6384816
Assay Type: RNA in situ
Annotation Date: 2020-01-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1778728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6384838
Age: postnatal day 7
Image: 9A Elmo2 P7
Specimen Label: 9A Elmo2 P7
Detected: true
Specimen Num: 34
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GXD Expression
GXD Expression
 
Probe: MGI:6384816
Assay Type: RNA in situ
Annotation Date: 2020-01-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1778728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6384838
Age: postnatal day 21
Image: 9A Elmo2 P21
Specimen Label: 9A Elmo2 P21
Detected: true
Specimen Num: 35
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GXD Expression
GXD Expression
Probe: MGI:6384816
Assay Type: RNA in situ
Annotation Date: 2020-01-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1754425
Pattern: Regionally restricted
Stage: TS25
Assay Id: MGI:6384838
Age: embryonic day 17.0
Image: 2A Elmo2 B6
Note: Expression in superficial part of cerebral cortex high compared to that of Elmo1 and Elmo3.
Specimen Label: 2A Elmo2 B6
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:6384816
Assay Type: RNA in situ
Annotation Date: 2020-01-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754425
Pattern: Regionally restricted
Stage: TS25
Assay Id: MGI:6384838
Age: embryonic day 17.0
Image: 2A Elmo2 rl
Note: Authors report layer-dependent expression seemed affected at E17.
Specimen Label: 2A Elmo2 rl
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:6384816
Assay Type: RNA in situ
Annotation Date: 2020-01-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1754425
Pattern: Regionally restricted
Stage: TS25
Assay Id: MGI:6384838
Age: embryonic day 17.0
Image: 6A Elmo1 + Elmo2
Note: Expression in superficial part of cerebral cortex high compared to that of Elmo1 and Elmo3.
Specimen Label: 6A Elmo1 + Elmo2
Detected: true
Specimen Num: 20
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GXD Expression
GXD Expression
 
Probe: MGI:6384816
Assay Type: RNA in situ
Annotation Date: 2020-01-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3267228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6384838
Age: postnatal day 21
Image: 5A Elmo2 (3rd row)
Specimen Label: 5A Elmo2 (3rd row)
Detected: true
Specimen Num: 15
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GXD Expression
GXD Expression
 
Probe: MGI:6384816
Assay Type: RNA in situ
Annotation Date: 2020-01-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3267228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6384838
Age: postnatal day 21
Image: 5D Elmo2 B6
Specimen Label: 5D Elmo2 B6
Detected: true
Specimen Num: 18
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GXD Expression
GXD Expression
 
Probe: MGI:6384816
Assay Type: RNA in situ
Annotation Date: 2020-01-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3543028
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6384838
Age: postnatal day 21
Image: 5A Elmo2 (2nd row)
Specimen Label: 5A Elmo2 (2nd row)
Detected: true
Specimen Num: 14
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GXD Expression
GXD Expression
 
Probe: MGI:6384816
Assay Type: RNA in situ
Annotation Date: 2020-01-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3284528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6384838
Age: postnatal day 21
Image: 7B Elmo2 rl
Specimen Label: 7B Elmo2 rl
Detected: true
Specimen Num: 27
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•
GXD Expression
GXD Expression
 
Probe: MGI:6384816
Assay Type: RNA in situ
Annotation Date: 2020-01-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3284528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6384838
Age: postnatal day 21
Image: 8C Elmo2 coronal
Specimen Label: 8C Elmo2 coronal
Detected: true
Specimen Num: 33
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GXD Expression
GXD Expression
 
Probe: MGI:6384816
Assay Type: RNA in situ
Annotation Date: 2020-01-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3583228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6384838
Age: postnatal day 21
Image: 7C Elmo2 B6
Specimen Label: 7C Elmo2 B6
Detected: true
Specimen Num: 28
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GXD Expression
GXD Expression
Probe: MGI:6384816
Assay Type: RNA in situ
Annotation Date: 2020-01-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691325
Pattern: Not Specified
Stage: TS25
Assay Id: MGI:6384838
Age: embryonic day 17.0
Image: 2A Elmo2 B6
Note: Expression in ventricular zone surrounding lateral ventricles.
Specimen Label: 2A Elmo2 B6
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:6384816
Assay Type: RNA in situ
Annotation Date: 2020-01-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3522328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6384838
Age: postnatal day 7
Image: 10A Elmo2 P7
Specimen Label: 10A Elmo2 P7
Detected: true
Specimen Num: 37
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:6384816
Assay Type: RNA in situ
Annotation Date: 2020-01-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3522328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6384838
Age: postnatal day 21
Image: 10A Elmo2 P21
Specimen Label: 10A Elmo2 P21
Detected: true
Specimen Num: 38
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:6384816
Assay Type: RNA in situ
Annotation Date: 2020-01-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3522328
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:6384838
Age: postnatal day 21
Image: 10B Elmo2 + GFAP
Note: Exprssion in Gfap-expressing Bergmann glial cells with cell bodies in the Purkinje cell layer.
Specimen Label: 10B Elmo2 + GFAP
Detected: true
Specimen Num: 39
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:6384816
Assay Type: RNA in situ
Annotation Date: 2020-01-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3522328
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:6384838
Age: postnatal day 21
Image: 10B Elmo2 + Calbindin
Note: Exprssion in Calb1-negative Bergmann glial cells with cell bodies in the Purkinje cell layer.
Specimen Label: 10B Elmo2 + Calbindin
Detected: true
Specimen Num: 40
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:6384816
Assay Type: RNA in situ
Annotation Date: 2020-01-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3277028
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6384838
Age: postnatal day 21
Image: 7B Elmo2 B6
Specimen Label: 7B Elmo2 B6
Detected: true
Specimen Num: 26
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:6384816
Assay Type: RNA in situ
Annotation Date: 2020-01-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3277028
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6384838
Age: postnatal day 21
Image: 7C Elmo2 B6
Specimen Label: 7C Elmo2 B6
Detected: true
Specimen Num: 28
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:6384816
Assay Type: RNA in situ
Annotation Date: 2020-01-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1754025
Pattern: Not Specified
Stage: TS25
Assay Id: MGI:6384838
Age: embryonic day 17.0
Image: 2A Elmo2 B6
Specimen Label: 2A Elmo2 B6
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:6384816
Assay Type: RNA in situ
Annotation Date: 2020-01-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3584728
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:6384838
Age: postnatal day 21
Image: 5A Elmo2 (1st row)
Note: Notatable expression in dorsal tenia tecta.
Specimen Label: 5A Elmo2 (1st row)
Detected: true
Specimen Num: 13
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:6384816
Assay Type: RNA in situ
Annotation Date: 2020-01-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3287025
Pattern: Not Specified
Stage: TS25
Assay Id: MGI:6384838
Age: embryonic day 17.0
Image: 2A Elmo2 B6
Specimen Label: 2A Elmo2 B6
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:6384816
Assay Type: RNA in situ
Annotation Date: 2020-01-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3287028
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6384838
Age: postnatal day 7
Image: 3B Elmo2 (middle)
Specimen Label: 3B Elmo2 (middle)
Detected: true
Specimen Num: 5
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:6384816
Assay Type: RNA in situ
Annotation Date: 2020-01-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3287028
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6384838
Age: postnatal day 21
Image: 4A Elmo2 WT
Specimen Label: 4A Elmo2 WT
Detected: true
Specimen Num: 9
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:6384816
Assay Type: RNA in situ
Annotation Date: 2020-01-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3527628
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6384838
Age: postnatal day 21
Image: 8C Elmo2 sagittal
Specimen Label: 8C Elmo2 sagittal
Detected: true
Specimen Num: 32
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:6384816
Assay Type: RNA in situ
Annotation Date: 2020-01-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3566728
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:6384838
Age: postnatal day 21
Image: 6C Elmo2 rl
Note: Layer-specific expression in parietal cortex seems disturbed in reeler mutant.
Specimen Label: 6C Elmo2 rl
Detected: true
Specimen Num: 24
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:6384816
Assay Type: RNA in situ
Annotation Date: 2020-01-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689425
Pattern: Regionally restricted
Stage: TS25
Assay Id: MGI:6384838
Age: embryonic day 17.0
Image: 2A Elmo2 rl
Note: Authors report overall expression not severely affect by the mutation.
Specimen Label: 2A Elmo2 rl
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:6384816
Assay Type: RNA in situ
Annotation Date: 2020-01-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:6384838
Age: postnatal day 21
Image: 4A Elmo2 rl
Note: Authors report regional expression patterns roughly similar to thos in B6 mouse brains.
Specimen Label: 4A Elmo2 rl
Detected: true
Specimen Num: 10
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:6384816
Assay Type: RNA in situ
Annotation Date: 2020-01-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3740228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6384838
Age: postnatal day 7
Image: 3B Elmo2 (lower)
Specimen Label: 3B Elmo2 (lower)
Detected: true
Specimen Num: 6
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:6384816
Assay Type: RNA in situ
Annotation Date: 2020-01-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3807528
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:6384838
Age: postnatal day 7
Image: 3C Elmo2 (center)
Specimen Label: 3C Elmo2 (center)
Detected: true
Specimen Num: 7
•
•
•
•
•
Publication
19439446 | J:164415
First Author: Ho E
Year: 2009
Journal: Mol Biol Cell
Title: Integrin-linked kinase interactions with ELMO2 modulate cell polarity.
Volume: 20
Issue: 13
Pages: 3033-43
•
•
•
•
•
Publication
27627840 | J:251533
First Author: Ho E
Year: 2016
Journal: Biochim Biophys Acta
Title: Integrin-linked kinase and ELMO2 modulate recycling endosomes in keratinocytes.
Volume: 1863
Issue: 12
Pages: 2892-2904
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:6384816
Assay Type: RNA in situ
Annotation Date: 2020-01-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:6384838
Age: postnatal day 21
Image: 4C Elmo1 + Elmo2 WT
Specimen Label: 4C Elmo1 + Elmo2 WT
Detected: true
Specimen Num: 11
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:6384816
Assay Type: RNA in situ
Annotation Date: 2020-01-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:6384838
Age: postnatal day 21
Image: 4C Elmo1 + Elmo2 rl
Note: Authors report different cellular expression patterns compared with that of B6 brains.
Specimen Label: 4C Elmo1 + Elmo2 rl
Detected: true
Specimen Num: 12
•
•
•
•
•
Publication
16443196 | J:106949
 
First Author: Katoh H
Year: 2006
Journal: Brain Res
Title: Differential distribution of ELMO1 and ELMO2 mRNAs in the developing mouse brain.
Volume: 1073-1074
Pages: 103-8
•
•
•
•
•
Publication
36400788 | J:331473
First Author: Tran V
Year: 2022
Journal: Nat Commun
Title: Biasing the conformation of ELMO2 reveals that myoblast fusion can be exploited to improve muscle regeneration.
Volume: 13
Issue: 1
Pages: 7077
•
•
•
•
•
Publication
24821968 | J:244219
First Author: Stevenson C
Year: 2014
Journal: J Immunol
Title: Essential role of Elmo1 in Dock2-dependent lymphocyte migration.
Volume: 192
Issue: 12
Pages: 6062-70
•
•
•
•
•
Protein
Q5GMG0
Organism: Mus musculus/domesticus
Length: 122  
Fragment?: true
•
•
•
•
•
Protein
A2A5A7
Organism: Mus musculus/domesticus
Length: 41  
Fragment?: true
•
•
•
•
•
Protein
D6RHT3
Organism: Mus musculus/domesticus
Length: 63  
Fragment?: false
•
•
•
•
•
Publication
25452388 | -
First Author: Toret CP
Year: 2014
Journal: J Cell Biol
Title: An Elmo-Dock complex locally controls Rho GTPases and actin remodeling during cadherin-mediated adhesion.
Volume: 207
Issue: 5
Pages: 577-87
•
•
•
•
•
Publication
25332238 | -
First Author: Abu-Thuraia A
Year: 2015
Journal: Mol Cell Biol
Title: Axl phosphorylates Elmo scaffold proteins to promote Rac activation and cell invasion.
Volume: 35
Issue: 1
Pages: 76-87
•
•
•
•
•
Protein
F6XD63
Organism: Mus musculus/domesticus
Length: 194  
Fragment?: true
•
•
•
•
•
Protein
F6YXR3
Organism: Mus musculus/domesticus
Length: 290  
Fragment?: true
•
•
•
•
•
Protein
Q8BHL5
Organism: Mus musculus/domesticus
Length: 732  
Fragment?: false
•
•
•
•
•
Publication
17452337 | -
First Author: Bowzard JB
Year: 2007
Journal: J Biol Chem
Title: ELMOD2 is an Arl2 GTPase-activating protein that also acts on Arfs.
Volume: 282
Issue: 24
Pages: 17568-80
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:6384816
Assay Type: RNA in situ
Annotation Date: 2020-01-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3526028
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6384838
Age: postnatal day 21
Specimen Label: Elmo2 P21 not shown
Detected: true
Specimen Num: 42
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:6384816
Assay Type: RNA in situ
Annotation Date: 2020-01-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3513028
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6384838
Age: postnatal day 21
Specimen Label: Elmo2 P21 not shown
Detected: true
Specimen Num: 42
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:6384816
Assay Type: RNA in situ
Annotation Date: 2020-01-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3284228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6384838
Age: postnatal day 21
Specimen Label: Elmo2 P21 not shown
Detected: true
Specimen Num: 42
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:6384816
Assay Type: RNA in situ
Annotation Date: 2020-01-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3529728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6384838
Age: postnatal day 21
Specimen Label: Elmo2 P21 not shown
Detected: true
Specimen Num: 42
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:6384816
Assay Type: RNA in situ
Annotation Date: 2020-01-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3520528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6384838
Age: postnatal day 21
Specimen Label: Elmo2 P21 not shown
Detected: true
Specimen Num: 42
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:6384816
Assay Type: RNA in situ
Annotation Date: 2020-01-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1754925
Pattern: Not Specified
Stage: TS25
Assay Id: MGI:6384838
Age: embryonic day 17.0
Specimen Label: Elmo2 E17 not shown
Detected: true
Specimen Num: 41
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:6384816
Assay Type: RNA in situ
Annotation Date: 2020-01-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1697428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6384838
Age: postnatal day 21
Specimen Label: Elmo2 P21 not shown
Detected: true
Specimen Num: 42
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:6384816
Assay Type: RNA in situ
Annotation Date: 2020-01-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3521928
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6384838
Age: postnatal day 21
Specimen Label: Elmo2 P21 not shown
Detected: true
Specimen Num: 42
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:6384816
Assay Type: RNA in situ
Annotation Date: 2020-01-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3554328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6384838
Age: postnatal day 21
Specimen Label: Elmo2 P21 not shown
Detected: true
Specimen Num: 42
•
•
•
•
•




MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

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Cambridge CB2 3EH, United Kingdom