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Search results 1 to 100 out of 156 for Elovl1

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Hits by Pathway

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Hits by Strain

Type Details Score
Gene
64834 | ELOVL1
Type: gene
Organism: human
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Gene
549398 | elovl1
Type: gene
Organism: frog, western clawed
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Gene
679532 | Elovl1
Type: gene
Organism: rat
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Gene
456820 | ELOVL1
Type: gene
Organism: chimpanzee
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Gene
540348 | ELOVL1
Type: gene
Organism: cattle
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Gene
100855761 | ELOVL1
Type: gene
Organism: dog, domestic
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Gene
424564 | ELOVL1
Type: gene
Organism: chicken
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Gene
700557 | ELOVL1
Type: gene
Organism: macaque, rhesus
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Protein Domain
IPR033681 | ELOVL1
Type: Family
Description: Elongation of very long chain fatty acids protein 1 (ELOVL1) is a component of the the long-chain fatty acids elongation cycle. It is a transmembrane enzyme in the endoplasmic reticulum that adds two carbons per cycle to long- and very long-chain fatty acids with a preference for condensing saturated C18 to C26 acyl-CoA substrates, with the highest activity towards C22:0 acyl-CoA [].
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Protein Coding Gene
MGI:1858959 | Elovl1
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
20937905 | J:165504
First Author: Ohno Y
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: ELOVL1 production of C24 acyl-CoAs is linked to C24 sphingolipid synthesis.
Volume: 107
Issue: 43
Pages: 18439-44
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Protein
Q9JLJ5
Organism: Mus musculus/domesticus
Length: 279  
Fragment?: false
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Protein
Q548M4
Organism: Mus musculus/domesticus
Length: 279  
Fragment?: false
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Publication
11891222 | J:76832
First Author: Asadi A
Year: 2002
Journal: J Biol Chem
Title: Elovl1 and p55Cdc genes are localized in a tail-to-tail array and are co-expressed in proliferating cells.
Volume: 277
Issue: 21
Pages: 18494-500
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Publication
29401594 | J:272194
First Author: Sassa T
Year: 2018
Journal: FASEB J
Title: Very long-chain tear film lipids produced by fatty acid elongase ELOVL1 prevent dry eye disease in mice.
Volume: 32
Issue: 6
Pages: 2966-2978
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Publication
30251650 | J:270156
First Author: Edagawa M
Year: 2018
Journal: Biochim Biophys Acta Mol Cell Biol Lipids
Title: Widespread tissue distribution and synthetic pathway of polyunsaturated C24:2 sphingolipids in mammals.
Volume: 1863
Issue: 12
Pages: 1441-1448
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Publication
22579584 | J:192993
First Author: Sassa T
Year: 2012
Journal: Biochim Biophys Acta
Title: A shift in sphingolipid composition from C24 to C16 increases susceptibility to apoptosis in HeLa cells.
Volume: 1821
Issue: 7
Pages: 1031-7
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Publication
34616039 | J:326213
First Author: Guttenplan KA
Year: 2021
Journal: Nature
Title: Neurotoxic reactive astrocytes induce cell death via saturated lipids.
Volume: 599
Issue: 7883
Pages: 102-107
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Publication
10791983 | J:61900
First Author: Tvrdik P
Year: 2000
Journal: J Cell Biol
Title: Role of a new mammalian gene family in the biosynthesis of very long chain fatty acids and sphingolipids.
Volume: 149
Issue: 3
Pages: 707-18
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Publication
33069870 | J:325267
First Author: Tanno H
Year: 2021
Journal: Biochim Biophys Acta Mol Cell Biol Lipids
Title: Production of branched-chain very-long-chain fatty acids by fatty acid elongases and their tissue distribution in mammals.
Volume: 1866
Issue: 1
Pages: 158842
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Publication
23689133 | J:204477
First Author: Sassa T
Year: 2013
Journal: Mol Cell Biol
Title: Impaired epidermal permeability barrier in mice lacking elovl1, the gene responsible for very-long-chain fatty acid production.
Volume: 33
Issue: 14
Pages: 2787-96
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Protein Coding Gene
MGP_CAROLIEiJ_G0026374 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0028667 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0028628 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0028578 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0028649 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0028363 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_1858959 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0029090 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0027797 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0028330 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0028478 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0028446 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0028580 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0028473 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0029127 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0027523 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0027876 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0028705 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0027346 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
37054712 | J:335285
   
First Author: Sassa T
Year: 2023
Journal: Cell Rep
Title: Involvement of ω-O-acylceramides and protein-bound ceramides in oral permeability barrier formation.
Pages: 112363
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Publication
20253178 | J:170151
First Author: LORCH J
Year: 1947
Journal: Q J Microsc Sci
Title: Note on the cytological localization of alkaline phosphatase.
Volume: 88
Issue: Pt 2
Pages: 159-61
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GXD Expression
GXD Expression
     
Probe: MGI:4437746
Assay Type: RT-PCR
Annotation Date: 2010-03-23
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:4437808
Age: postnatal adult
Specimen Label: wild-type
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:4437746
Assay Type: RT-PCR
Annotation Date: 2010-03-23
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:4437808
Age: postnatal adult
Specimen Label: Szt2m1Frk
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:5824359
Assay Type: RT-PCR
Annotation Date: 2017-02-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1752526
Stage: TS26
Assay Id: MGI:5824387
Age: embryonic day 18.5
Specimen Label: +/+
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:5824359
Assay Type: RT-PCR
Annotation Date: 2017-02-17
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1752526
Stage: TS26
Assay Id: MGI:5824387
Age: embryonic day 18.5
Specimen Label: -/-
Detected: false
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:5824359
Assay Type: RT-PCR
Annotation Date: 2017-02-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1752526
Stage: TS26
Assay Id: MGI:5824504
Age: embryonic day 18.5
Specimen Label: +/+
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:5824359
Assay Type: RT-PCR
Annotation Date: 2017-02-17
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1752526
Stage: TS26
Assay Id: MGI:5824504
Age: embryonic day 18.5
Specimen Label: -/-
Detected: false
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:6423349
Assay Type: RT-PCR
Annotation Date: 2020-05-19
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1752826
Stage: TS26
Assay Id: MGI:6423362
Age: embryonic day 18.5
Specimen Label: WT
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:6423349
Assay Type: RT-PCR
Annotation Date: 2020-05-19
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1752826
Stage: TS26
Assay Id: MGI:6423362
Age: embryonic day 18.5
Specimen Label: KO
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:6781805
Assay Type: RT-PCR
Annotation Date: 2021-10-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603910
Stage: TS10
Assay Id: MGI:6781897
Age: embryonic day 7.0
Specimen Label: 7 dpc
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:6781805
Assay Type: RT-PCR
Annotation Date: 2021-10-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603918
Stage: TS18
Assay Id: MGI:6781897
Age: embryonic day 11.0
Specimen Label: 11 dpc
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
     
Probe: MGI:6781805
Assay Type: RT-PCR
Annotation Date: 2021-10-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603923
Stage: TS23
Assay Id: MGI:6781897
Age: embryonic day 15.0
Specimen Label: 15 dpc
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
     
Probe: MGI:6781805
Assay Type: RT-PCR
Annotation Date: 2021-10-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603925
Stage: TS25
Assay Id: MGI:6781897
Age: embryonic day 17.0
Specimen Label: 17 dpc
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
     
Probe: MGI:6781805
Assay Type: RT-PCR
Annotation Date: 2021-10-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:6781897
Age: postnatal adult
Specimen Label: Brain
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
     
Probe: MGI:6781805
Assay Type: RT-PCR
Annotation Date: 2021-10-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:6781897
Age: postnatal adult
Specimen Label: Heart
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
     
Probe: MGI:6781805
Assay Type: RT-PCR
Annotation Date: 2021-10-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:6781897
Age: postnatal adult
Specimen Label: Kidney
Detected: true
Specimen Num: 8
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GXD Expression
GXD Expression
     
Probe: MGI:6781805
Assay Type: RT-PCR
Annotation Date: 2021-10-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:6781897
Age: postnatal adult
Specimen Label: Liver
Detected: true
Specimen Num: 9
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GXD Expression
GXD Expression
     
Probe: MGI:6781805
Assay Type: RT-PCR
Annotation Date: 2021-10-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672828
Stage: TS28
Assay Id: MGI:6781897
Age: postnatal adult
Specimen Label: Lung
Detected: true
Specimen Num: 10
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GXD Expression
GXD Expression
     
Probe: MGI:6781805
Assay Type: RT-PCR
Annotation Date: 2021-10-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3598828
Stage: TS28
Assay Id: MGI:6781897
Age: postnatal adult
Specimen Label: Sk.Mus
Detected: true
Specimen Num: 11
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GXD Expression
GXD Expression
     
Probe: MGI:6781805
Assay Type: RT-PCR
Annotation Date: 2021-10-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:6781897
Age: postnatal adult
Specimen Label: Spleen
Detected: true
Specimen Num: 12
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GXD Expression
GXD Expression
     
Probe: MGI:6781805
Assay Type: RT-PCR
Annotation Date: 2021-10-26
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:6781897
Age: postnatal adult
Specimen Label: Testis
Detected: true
Specimen Num: 13
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GXD Expression
GXD Expression
     
Probe: MGI:6781805
Assay Type: RT-PCR
Annotation Date: 2021-10-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1752528
Stage: TS28
Assay Id: MGI:6781897
Age: postnatal adult
Specimen Label: Skin
Detected: true
Specimen Num: 14
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GXD Expression
GXD Expression
     
Probe: MGI:6781805
Assay Type: RT-PCR
Annotation Date: 2021-10-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1736220
Stage: TS20
Assay Id: MGI:6781897
Age: embryonic day 12.5
Specimen Label: WT 12.5
Detected: true
Specimen Num: 15
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GXD Expression
GXD Expression
     
Probe: MGI:6781805
Assay Type: RT-PCR
Annotation Date: 2021-10-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1894821
Stage: TS21
Assay Id: MGI:6781897
Age: embryonic day 13.5
Specimen Label: WT 13.5
Detected: true
Specimen Num: 16
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GXD Expression
GXD Expression
     
Probe: MGI:6781805
Assay Type: RT-PCR
Annotation Date: 2021-10-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1894822
Stage: TS22
Assay Id: MGI:6781897
Age: embryonic day 14.5
Specimen Label: WT 14.5
Detected: true
Specimen Num: 17
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GXD Expression
GXD Expression
     
Probe: MGI:6781805
Assay Type: RT-PCR
Annotation Date: 2021-10-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1894823
Stage: TS23
Assay Id: MGI:6781897
Age: embryonic day 15.5
Specimen Label: WT 15.5
Detected: true
Specimen Num: 18
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GXD Expression
GXD Expression
     
Probe: MGI:6781805
Assay Type: RT-PCR
Annotation Date: 2021-10-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1736321
Stage: TS21
Assay Id: MGI:6781897
Age: embryonic day 13.5
Specimen Label: WT MEE 13.5
Detected: true
Specimen Num: 19
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GXD Expression
GXD Expression
     
Probe: MGI:6781805
Assay Type: RT-PCR
Annotation Date: 2021-10-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1736322
Stage: TS22
Assay Id: MGI:6781897
Age: embryonic day 14.5
Specimen Label: WT MEE 14.5
Detected: true
Specimen Num: 20
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GXD Expression
GXD Expression
     
Probe: MGI:6781805
Assay Type: RT-PCR
Annotation Date: 2021-10-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1736321
Stage: TS21
Assay Id: MGI:6781897
Age: embryonic day 13.5
Specimen Label: Mutant 13.5
Detected: true
Specimen Num: 21
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GXD Expression
GXD Expression
     
Probe: MGI:6781805
Assay Type: RT-PCR
Annotation Date: 2021-10-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1736322
Stage: TS22
Assay Id: MGI:6781897
Age: embryonic day 14.5
Specimen Label: Mutant 14.5
Detected: true
Specimen Num: 22
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GXD Expression
GXD Expression
     
Probe: MGI:7461603
Assay Type: RT-PCR
Annotation Date: 2023-04-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1752526
Stage: TS26
Assay Id: MGI:7461625
Age: embryonic day 18.5
Specimen Label: WT
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:7461603
Assay Type: RT-PCR
Annotation Date: 2023-04-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1752526
Stage: TS26
Assay Id: MGI:7461625
Age: embryonic day 18.5
Specimen Label: Pnpla1 tm1a
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:5824379
Assay Type: RNA in situ
Annotation Date: 2017-02-17
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3278626
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:5824530
Age: embryonic day 18.5
Specimen Label: S4 +/+
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:5824379
Assay Type: RNA in situ
Annotation Date: 2017-02-17
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3278626
Stage: TS26
Assay Id: MGI:5824530
Age: embryonic day 18.5
Specimen Label: S4 -/-
Detected: false
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:5824379
Assay Type: RNA in situ
Annotation Date: 2017-02-17
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3278526
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:5824530
Age: embryonic day 18.5
Specimen Label: S4 +/+
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:5824379
Assay Type: RNA in situ
Annotation Date: 2017-02-17
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3278526
Stage: TS26
Assay Id: MGI:5824530
Age: embryonic day 18.5
Specimen Label: S4 -/-
Detected: false
Specimen Num: 2
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Publication
29174370 | J:261184
First Author: Honda Y
Year: 2018
Journal: J Invest Dermatol
Title: Decreased Skin Barrier Lipid Acylceramide and Differentiation-Dependent Gene Expression in Ichthyosis Gene Nipal4-Knockout Mice.
Volume: 138
Issue: 4
Pages: 741-749
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Publication
19624305 | J:150942
First Author: Frankel WN
Year: 2009
Journal: Genes Brain Behav
Title: Szt2, a novel gene for seizure threshold in mice.
Volume: 8
Issue: 5
Pages: 568-76
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Publication
21574244 | J:174238
First Author: Rorick NK
Year: 2011
Journal: Am J Med Genet A
Title: Genomic strategy identifies a missense mutation in WD-repeat domain 65 (WDR65) in an individual with Van der Woude syndrome.
Volume: 155A
Issue: 6
Pages: 1314-21
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Publication
31356814 | J:286705
First Author: Miyamoto M
Year: 2020
Journal: J Invest Dermatol
Title: Severe Skin Permeability Barrier Dysfunction in Knockout Mice Deficient in a Fatty Acid ω-Hydroxylase Crucial to Acylceramide Production.
Volume: 140
Issue: 2
Pages: 319-326.e4
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Publication
16949565 | J:114626
First Author: Yu Z
Year: 2006
Journal: Dev Biol
Title: The Grainyhead-like epithelial transactivator Get-1/Grhl3 regulates epidermal terminal differentiation and interacts functionally with LMO4.
Volume: 299
Issue: 1
Pages: 122-36
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Publication
28369476 | J:242353
First Author: Pichery M
Year: 2017
Journal: Hum Mol Genet
Title: PNPLA1 defects in patients with autosomal recessive congenital ichthyosis and KO mice sustain PNPLA1 irreplaceable function in epidermal omega-O-acylceramide synthesis and skin permeability barrier.
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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