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Search results 1 to 100 out of 282 for Elovl4

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0.038s
Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: chimpanzee
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: macaque, rhesus
Protein Domain
Type: Family
Description: Elongation of very long chain fatty acids protein 4 (ELOVL4) is a component of the the long-chain fatty acids elongation cycle. It is a transmembrane enzyme in the endoplasmic reticulum that adds two carbons per cycle to long- and very long-chain fatty acids with a preference for elongating C24:0 and C26:0 acyl-CoAs [].
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein
Organism: Mus musculus/domesticus
Length: 312  
Fragment?: false
Publication
First Author: Vasireddy V
Year: 2006
Journal: Invest Ophthalmol Vis Sci
Title: Elovl4 5-bp-deletion knock-in mice develop progressive photoreceptor degeneration.
Volume: 47
Issue: 10
Pages: 4558-68
Publication
First Author: Lagali PS
Year: 2003
Journal: Invest Ophthalmol Vis Sci
Title: Evolutionarily conserved ELOVL4 gene expression in the vertebrate retina.
Volume: 44
Issue: 7
Pages: 2841-50
Publication
First Author: Vasireddy V
Year: 2009
Journal: Exp Eye Res
Title: Elovl4 5-bp deletion knock-in mouse model for Stargardt-like macular degeneration demonstrates accumulation of ELOVL4 and lipofuscin.
Volume: 89
Issue: 6
Pages: 905-12
Publication  
First Author: Zhang XM
Year: 2003
Journal: Mol Vis
Title: Elovl4 mRNA distribution in the developing mouse retina and phylogenetic conservation of Elovl4 genes.
Volume: 9
Pages: 301-7
Publication
First Author: McMahon A
Year: 2011
Journal: J Lipid Res
Title: Epidermal expression of an Elovl4 transgene rescues neonatal lethality of homozygous Stargardt disease-3 mice.
Volume: 52
Issue: 6
Pages: 1128-38
Publication
First Author: Li W
Year: 2007
Journal: Vision Res
Title: Elovl4 haploinsufficiency does not induce early onset retinal degeneration in mice.
Volume: 47
Issue: 5
Pages: 714-22
Publication
First Author: Zhang K
Year: 2001
Journal: Nat Genet
Title: A 5-bp deletion in ELOVL4 is associated with two related forms of autosomal dominant macular dystrophy.
Volume: 27
Issue: 1
Pages: 89-93
Publication
First Author: Agbaga MP
Year: 2010
Journal: J Lipid Res
Title: Retinal very long-chain PUFAs: new insights from studies on ELOVL4 protein.
Volume: 51
Issue: 7
Pages: 1624-42
Publication
First Author: Logan S
Year: 2014
Journal: J Lipid Res
Title: Endoplasmic reticulum microenvironment and conserved histidines govern ELOVL4 fatty acid elongase activity.
Volume: 55
Issue: 4
Pages: 698-708
Publication
First Author: McMahon A
Year: 2014
Journal: Invest Ophthalmol Vis Sci
Title: A role for ELOVL4 in the mouse meibomian gland and sebocyte cell biology.
Volume: 55
Issue: 5
Pages: 2832-40
Publication
First Author: Mandal NA
Year: 2014
Journal: Invest Ophthalmol Vis Sci
Title: In vivo effect of mutant ELOVL4 on the expression and function of wild-type ELOVL4.
Volume: 55
Issue: 4
Pages: 2705-13
Publication
First Author: Ohno Y
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: ELOVL1 production of C24 acyl-CoAs is linked to C24 sphingolipid synthesis.
Volume: 107
Issue: 43
Pages: 18439-44
Publication
First Author: Cameron DJ
Year: 2007
Journal: Int J Biol Sci
Title: Essential role of Elovl4 in very long chain fatty acid synthesis, skin permeability barrier function, and neonatal survival.
Volume: 3
Issue: 2
Pages: 111-9
Publication
First Author: Raz-Prag D
Year: 2006
Journal: Invest Ophthalmol Vis Sci
Title: Haploinsufficiency is not the key mechanism of pathogenesis in a heterozygous Elovl4 knockout mouse model of STGD3 disease.
Volume: 47
Issue: 8
Pages: 3603-11
Publication
First Author: Schori C
Year: 2018
Journal: PLoS One
Title: Elovl4 5-bp deletion does not accelerate cone photoreceptor degeneration in an all-cone mouse.
Volume: 13
Issue: 1
Pages: e0190514
Publication
First Author: McMahon A
Year: 2007
Journal: FEBS Lett
Title: A Stargardt disease-3 mutation in the mouse Elovl4 gene causes retinal deficiency of C32-C36 acyl phosphatidylcholines.
Volume: 581
Issue: 28
Pages: 5459-63
Publication
First Author: Barabas P
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Role of ELOVL4 and very long-chain polyunsaturated fatty acids in mouse models of Stargardt type 3 retinal degeneration.
Volume: 110
Issue: 13
Pages: 5181-6
Publication
First Author: Vasireddy V
Year: 2007
Journal: Hum Mol Genet
Title: Loss of functional ELOVL4 depletes very long-chain fatty acids (> or =C28) and the unique omega-O-acylceramides in skin leading to neonatal death.
Volume: 16
Issue: 5
Pages: 471-82
Publication
First Author: Li W
Year: 2007
Journal: Int J Biol Sci
Title: Depletion of ceramides with very long chain fatty acids causes defective skin permeability barrier function, and neonatal lethality in ELOVL4 deficient mice.
Volume: 3
Issue: 2
Pages: 120-8
Publication
First Author: Hopiavuori BR
Year: 2018
Journal: Mol Neurobiol
Title: Homozygous Expression of Mutant ELOVL4 Leads to Seizures and Death in a Novel Animal Model of Very Long-Chain Fatty Acid Deficiency.
Volume: 55
Issue: 2
Pages: 1795-1813
Publication
First Author: Kady NM
Year: 2018
Journal: Diabetes
Title: ELOVL4-Mediated Production of Very Long-Chain Ceramides Stabilizes Tight Junctions and Prevents Diabetes-Induced Retinal Vascular Permeability.
Volume: 67
Issue: 4
Pages: 769-781
Publication
First Author: Agbaga MP
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: Role of Stargardt-3 macular dystrophy protein (ELOVL4) in the biosynthesis of very long chain fatty acids.
Volume: 105
Issue: 35
Pages: 12843-8
Publication
First Author: Esteve-Rudd J
Year: 2018
Journal: Proc Natl Acad Sci U S A
Title: Defective phagosome motility and degradation in cell nonautonomous RPE pathogenesis of a dominant macular degeneration.
Volume: 115
Issue: 21
Pages: 5468-5473
Publication
First Author: Bennett LD
Year: 2014
Journal: Invest Ophthalmol Vis Sci
Title: Effect of reduced retinal VLC-PUFA on rod and cone photoreceptors.
Volume: 55
Issue: 5
Pages: 3150-7
Publication
First Author: Bennett LD
Year: 2014
Journal: Invest Ophthalmol Vis Sci
Title: Examination of VLC-PUFA-deficient photoreceptor terminals.
Volume: 55
Issue: 7
Pages: 4063-72
Publication  
First Author: Gorusupudi A
Year: 2021
Journal: Proc Natl Acad Sci U S A
Title: Retinal bioavailability and functional effects of a synthetic very-long-chain polyunsaturated fatty acid in mice.
Volume: 118
Issue: 6
Publication
First Author: Mandal MN
Year: 2004
Journal: Genomics
Title: Characterization of mouse orthologue of ELOVL4: genomic organization and spatial and temporal expression.
Volume: 83
Issue: 4
Pages: 626-35
Publication  
First Author: McMahon A
Year: 2007
Journal: Mol Vis
Title: Retinal pathology and skin barrier defect in mice carrying a Stargardt disease-3 mutation in elongase of very long chain fatty acids-4.
Volume: 13
Pages: 258-72
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
GXD Expression      
Probe: MGI:5824362
Assay Type: RT-PCR
Annotation Date: 2017-02-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1752526
Stage: TS26
Assay Id: MGI:5824509
Age: embryonic day 18.5
Specimen Label: +/+
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:5824362
Assay Type: RT-PCR
Annotation Date: 2017-02-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1752526
Stage: TS26
Assay Id: MGI:5824509
Age: embryonic day 18.5
Specimen Label: -/-
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:6161796
Assay Type: Northern blot
Annotation Date: 2018-06-21
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:6161808
Age: postnatal week 33
Specimen Label: brain
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:6161796
Assay Type: Northern blot
Annotation Date: 2018-06-21
Strength: Absent
Sex: Male
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:6161808
Age: postnatal week 33
Specimen Label: liver
Detected: false
Specimen Num: 2
GXD Expression      
Probe: MGI:6161796
Assay Type: Northern blot
Annotation Date: 2018-06-21
Strength: Absent
Sex: Male
Emaps: EMAPS:1672828
Stage: TS28
Assay Id: MGI:6161808
Age: postnatal week 33
Specimen Label: lungs
Detected: false
Specimen Num: 3
GXD Expression      
Probe: MGI:6161796
Assay Type: Northern blot
Annotation Date: 2018-06-21
Strength: Present
Sex: Male
Emaps: EMAPS:1716828
Stage: TS28
Assay Id: MGI:6161808
Age: postnatal week 33
Specimen Label: retina
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:6161796
Assay Type: Northern blot
Annotation Date: 2018-06-21
Strength: Absent
Sex: Male
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:6161808
Age: postnatal week 33
Specimen Label: kidney
Detected: false
Specimen Num: 5
GXD Expression      
Probe: MGI:6161796
Assay Type: Northern blot
Annotation Date: 2018-06-21
Strength: Absent
Sex: Male
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:6161808
Age: postnatal week 33
Specimen Label: heart
Detected: false
Specimen Num: 6
GXD Expression      
Probe: MGI:6161796
Assay Type: Northern blot
Annotation Date: 2018-06-21
Strength: Present
Sex: Male
Emaps: EMAPS:1752528
Stage: TS28
Assay Id: MGI:6161808
Age: postnatal week 33
Specimen Label: skin
Detected: true
Specimen Num: 7
GXD Expression      
Probe: MGI:6161796
Assay Type: Northern blot
Annotation Date: 2018-06-21
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1603910
Stage: TS10
Assay Id: MGI:6161809
Age: embryonic day 7.0
Specimen Label: E7
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:6161796
Assay Type: Northern blot
Annotation Date: 2018-06-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603918
Stage: TS18
Assay Id: MGI:6161809
Age: embryonic day 11.0
Specimen Label: E11
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:6161796
Assay Type: Northern blot
Annotation Date: 2018-06-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603923
Stage: TS23
Assay Id: MGI:6161809
Age: embryonic day 15.0
Specimen Label: E15
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:6161796
Assay Type: Northern blot
Annotation Date: 2018-06-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603925
Stage: TS25
Assay Id: MGI:6161809
Age: embryonic day 17.0
Specimen Label: E17
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:6161800
Assay Type: RT-PCR
Annotation Date: 2018-06-21
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:6161815
Age: postnatal week 33
Specimen Label: brain
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:6161800
Assay Type: RT-PCR
Annotation Date: 2018-06-21
Strength: Absent
Sex: Male
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:6161815
Age: postnatal week 33
Specimen Label: liver
Detected: false
Specimen Num: 2
GXD Expression      
Probe: MGI:6161800
Assay Type: RT-PCR
Annotation Date: 2018-06-21
Strength: Present
Sex: Male
Emaps: EMAPS:1672828
Stage: TS28
Assay Id: MGI:6161815
Age: postnatal week 33
Specimen Label: lungs
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:6161800
Assay Type: RT-PCR
Annotation Date: 2018-06-21
Strength: Present
Sex: Male
Emaps: EMAPS:1716828
Stage: TS28
Assay Id: MGI:6161815
Age: postnatal week 33
Specimen Label: retina
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:6161800
Assay Type: RT-PCR
Annotation Date: 2018-06-21
Strength: Present
Sex: Male
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:6161815
Age: postnatal week 33
Specimen Label: heart
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:6161800
Assay Type: RT-PCR
Annotation Date: 2018-06-21
Strength: Present
Sex: Male
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:6161815
Age: postnatal week 33
Specimen Label: kidney
Detected: true
Specimen Num: 6
GXD Expression      
Probe: MGI:6161800
Assay Type: RT-PCR
Annotation Date: 2018-06-21
Strength: Present
Sex: Male
Emaps: EMAPS:1752528
Stage: TS28
Assay Id: MGI:6161815
Age: postnatal week 33
Specimen Label: skin
Detected: true
Specimen Num: 7
GXD Expression      
Probe: MGI:6161800
Assay Type: RT-PCR
Annotation Date: 2018-06-21
Strength: Present
Sex: Male
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:6161815
Age: postnatal week 33
Specimen Label: spleen
Detected: true
Specimen Num: 8
GXD Expression      
Probe: MGI:6161800
Assay Type: RT-PCR
Annotation Date: 2018-06-21
Strength: Present
Sex: Male
Emaps: EMAPS:1783828
Stage: TS28
Assay Id: MGI:6161815
Age: postnatal week 33
Specimen Label: lens
Detected: true
Specimen Num: 9
GXD Expression      
Probe: MGI:6161800
Assay Type: RT-PCR
Annotation Date: 2018-06-21
Strength: Present
Sex: Male
Emaps: EMAPS:3598828
Stage: TS28
Assay Id: MGI:6161815
Age: postnatal week 33
Specimen Label: sk. muscle
Detected: true
Specimen Num: 10
GXD Expression      
Probe: MGI:6161800
Assay Type: RT-PCR
Annotation Date: 2018-06-21
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:6161815
Age: postnatal week 33
Specimen Label: testis
Detected: true
Specimen Num: 11
GXD Expression      
Probe: MGI:6161800
Assay Type: RT-PCR
Annotation Date: 2018-06-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603910
Stage: TS10
Assay Id: MGI:6161817
Age: embryonic day 7.0
Specimen Label: E7
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:6161800
Assay Type: RT-PCR
Annotation Date: 2018-06-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603918
Stage: TS18
Assay Id: MGI:6161817
Age: embryonic day 11.0
Specimen Label: E11
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:6161800
Assay Type: RT-PCR
Annotation Date: 2018-06-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603923
Stage: TS23
Assay Id: MGI:6161817
Age: embryonic day 15.0
Specimen Label: E15
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:6161800
Assay Type: RT-PCR
Annotation Date: 2018-06-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603925
Stage: TS25
Assay Id: MGI:6161817
Age: embryonic day 17.0
Specimen Label: E17
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:6161800
Assay Type: RT-PCR
Annotation Date: 2018-06-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689427
Stage: TS27
Assay Id: MGI:6161818
Age: postnatal day 1
Specimen Label: P1
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:6161800
Assay Type: RT-PCR
Annotation Date: 2018-06-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689427
Stage: TS27
Assay Id: MGI:6161818
Age: postnatal day 3
Specimen Label: P3
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:6161800
Assay Type: RT-PCR
Annotation Date: 2018-06-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:6161818
Age: postnatal day 5
Specimen Label: P5
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:6161800
Assay Type: RT-PCR
Annotation Date: 2018-06-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:6161818
Age: postnatal day 7
Specimen Label: P7
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:6161800
Assay Type: RT-PCR
Annotation Date: 2018-06-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:6161818
Age: postnatal day 10
Specimen Label: P10
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:6161800
Assay Type: RT-PCR
Annotation Date: 2018-06-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:6161818
Age: postnatal day 15
Specimen Label: P15
Detected: true
Specimen Num: 6
GXD Expression      
Probe: MGI:6161800
Assay Type: RT-PCR
Annotation Date: 2018-06-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:6161818
Age: postnatal day 30
Specimen Label: P30
Detected: true
Specimen Num: 7
GXD Expression      
Probe: MGI:6161800
Assay Type: RT-PCR
Annotation Date: 2018-06-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:6161818
Age: postnatal day 45
Specimen Label: P45
Detected: true
Specimen Num: 8
GXD Expression      
Probe: MGI:6161800
Assay Type: RT-PCR
Annotation Date: 2018-06-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:6161818
Age: postnatal day 60
Specimen Label: P60
Detected: true
Specimen Num: 9
GXD Expression      
Probe: MGI:6161800
Assay Type: RT-PCR
Annotation Date: 2018-06-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:6161818
Age: postnatal day 163
Specimen Label: P163
Detected: true
Specimen Num: 10
GXD Expression      
Probe: MGI:6161800
Assay Type: RT-PCR
Annotation Date: 2018-06-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1619827
Stage: TS27
Assay Id: MGI:6161820
Age: postnatal day 1
Specimen Label: P1
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:6161800
Assay Type: RT-PCR
Annotation Date: 2018-06-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1619827
Stage: TS27
Assay Id: MGI:6161820
Age: postnatal day 3
Specimen Label: P3
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:6161800
Assay Type: RT-PCR
Annotation Date: 2018-06-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1619828
Stage: TS28
Assay Id: MGI:6161820
Age: postnatal day 5
Specimen Label: P5
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:6161800
Assay Type: RT-PCR
Annotation Date: 2018-06-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1619828
Stage: TS28
Assay Id: MGI:6161820
Age: postnatal day 7
Specimen Label: P7
Detected: true
Specimen Num: 4