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Search results 1 to 93 out of 93 for Elp2

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Hits by Category

Hits by Strain

Type Details Score
Gene
55250 | ELP2
Type: gene
Organism: human
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Gene
548516 | elp2
Type: gene
Organism: frog, western clawed
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Gene
307545 | Elp2
Type: gene
Organism: rat
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Gene
480158 | ELP2
Type: gene
Organism: dog, domestic
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Gene
455378 | ELP2
Type: gene
Organism: chimpanzee
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Gene
511041 | ELP2
Type: gene
Organism: cattle
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Gene
420980 | ELP2
Type: gene
Organism: chicken
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Gene
560338 | elp2
Type: gene
Organism: zebrafish
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Gene
709483 | ELP2
Type: gene
Organism: macaque, rhesus
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Protein Coding Gene
MGI:1889642 | Elp2
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Domain
IPR037289 | Elp2
Type: Family
Description: Elongator complex protein 2 (Elp2) is a component of the RNA polymerase II elongator complex, which is a major histone acetyltransferase component of the RNA polymerase II (RNAPII) holoenzyme. The eukaryotic elongator complex has been associated with many cellular activities, including transcriptional elongation [, ], but its main function is tRNA modification [, ]. It is required for the formation of 5-methoxy-carbonylmethyl (mcm5) and 5-carbamoylmethyl (ncm5) groups on uridine nucleosides present at the wobble position of many tRNAs [, ].
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Publication
33976153 | J:306113
First Author: Kojic M
Year: 2021
Journal: Nat Commun
Title: Elp2 mutations perturb the epitranscriptome and lead to a complex neurodevelopmental phenotype.
Volume: 12
Issue: 1
Pages: 2678
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Protein
Q91WG4
Organism: Mus musculus/domesticus
Length: 831  
Fragment?: false
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Publication
29723529 | J:270547
First Author: Lu S
Year: 2018
Journal: Biochem Biophys Res Commun
Title: Suppression of Elp2 prevents renal fibrosis and inflammation induced by unilateral ureter obstruction (UUO) via inactivating Stat3-regulated TGF-β1 and NF-κB pathways.
Volume: 501
Issue: 2
Pages: 400-407
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Protein
Q8C8Q3
Organism: Mus musculus/domesticus
Length: 266  
Fragment?: false
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Publication
10024884 | -
First Author: Otero G
Year: 1999
Journal: Mol Cell
Title: Elongator, a multisubunit component of a novel RNA polymerase II holoenzyme for transcriptional elongation.
Volume: 3
Issue: 1
Pages: 109-18
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Publication
11689709 | -
First Author: Krogan NJ
Year: 2001
Journal: Mol Cell Biol
Title: Characterization of a six-subunit holo-elongator complex required for the regulated expression of a group of genes in Saccharomyces cerevisiae.
Volume: 21
Issue: 23
Pages: 8203-12
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Publication
15769872 | -
First Author: Huang B
Year: 2005
Journal: RNA
Title: An early step in wobble uridine tRNA modification requires the Elongator complex.
Volume: 11
Issue: 4
Pages: 424-36
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Publication
22889844 | -
First Author: Glatt S
Year: 2012
Journal: Transcription
Title: Elongator: transcriptional or translational regulator?
Volume: 3
Issue: 6
Pages: 273-6
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Publication
23165209 | -
First Author: Bauer F
Year: 2012
Journal: Cell Cycle
Title: A coordinated codon-dependent regulation of translation by Elongator.
Volume: 11
Issue: 24
Pages: 4524-9
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Publication
31309145 | -
First Author: Dauden MI
Year: 2019
Journal: Sci Adv
Title: Molecular basis of tRNA recognition by the Elongator complex.
Volume: 5
Issue: 7
Pages: eaaw2326
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Protein Coding Gene
MGP_CAROLIEiJ_G0022052 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0024203 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0024168 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0024137 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0024168 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0023936 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_1889642 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0024610 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0023410 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0023904 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0024036 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0024002 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0024117 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0024030 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0024658 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0023154 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0023474 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0018786 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0022963 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
11714725 | J:99828
First Author: Hawkes NA
Year: 2002
Journal: J Biol Chem
Title: Purification and characterization of the human elongator complex.
Volume: 277
Issue: 4
Pages: 3047-52
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GXD Expression
GXD Expression
   
Probe: MGI:952410
Assay Type: RNA in situ
Annotation Date: 2009-08-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3270422
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:4354738
Age: embryonic day 14.5
Specimen Label: Table S5 - Statip1
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:952410
Assay Type: RNA in situ
Annotation Date: 2009-08-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3271122
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:4354738
Age: embryonic day 14.5
Note: Expression is present in the upper and lower cortical plate.
Specimen Label: Table S5 - Statip1
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:3585098
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1647028
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:3585715
Age: postnatal day 6
Note: Expression was widespread.
Specimen Label: CNS
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
 
Probe: MGI:3585098
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1915726
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:3585715
Age: embryonic day 18.0
Note: Expression was detected in the outer neuroblastic layer.
Specimen Label: E18
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:3585098
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1915727
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:3585715
Age: postnatal day 0-1
Note: Expression was detected in the outer neuroblastic layer.
Specimen Label: P0/1
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
 
Probe: MGI:3585098
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1915727
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:3585715
Age: postnatal day 2-3
Note: Expression was detected in the outer neuroblastic layer but was higher in the vitreal outer neuroblastic layer.
Specimen Label: P2/3
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
 
Probe: MGI:3585098
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1915728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:3585715
Age: postnatal day 4-5
Note: Expression was detected in the outer neuroblastic layer but was higher in the vitreal outer neuroblastic layer.
Specimen Label: P4/5
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
   
Probe: MGI:3585098
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Present
Sex: Male
Emaps: EMAPS:1915728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:3585715
Age: postnatal adult
Specimen Label: Adult
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
   
Probe: MGI:3585098
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684624
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:3585715
Age: embryonic day 16.0
Specimen Label: Embryo
Detected: true
Specimen Num: 8
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GXD Expression
GXD Expression
 
Probe: MGI:3585098
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1859224
Pattern: Regionally restricted
Stage: TS24
Assay Id: MGI:3585715
Age: embryonic day 16.0
Note: Expression was detected in the outer neuroblastic layer.
Specimen Label: E16
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:952410
Assay Type: RNA in situ
Annotation Date: 2009-08-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754722
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:4354738
Age: embryonic day 14.5
Specimen Label: Table S5 - Statip1
Detected: true
Specimen Num: 1
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Publication
10954736 | J:64303
First Author: Collum RG
Year: 2000
Journal: Proc Natl Acad Sci U S A
Title: A Stat3-interacting protein (StIP1) regulates cytokine signal transduction.
Volume: 97
Issue: 18
Pages: 10120-5
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Publication
16870469 | J:116523
First Author: Okuda H
Year: 2006
Journal: Mol Cell Neurosci
Title: Novel interaction between HMGA1a and StIP1 in murine terminally differentiated retina.
Volume: 33
Issue: 1
Pages: 81-7
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Publication
19015235 | J:145561
First Author: Chen YT
Year: 2009
Journal: Mol Cell Biol
Title: Loss of mouse Ikbkap, a subunit of elongator, leads to transcriptional deficits and embryonic lethality that can be rescued by human IKBKAP.
Volume: 29
Issue: 3
Pages: 736-44
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Publication
39747033 | J:360776
First Author: Di Michele M
Year: 2025
Journal: Nat Commun
Title: E4F1 coordinates pyruvate metabolism and the activity of the elongator complex to ensure translation fidelity during brain development.
Volume: 16
Issue: 1
Pages: 67
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Publication
19521500 | J:149737
First Author: Sansom SN
Year: 2009
Journal: PLoS Genet
Title: The level of the transcription factor Pax6 is essential for controlling the balance between neural stem cell self-renewal and neurogenesis.
Volume: 5
Issue: 6
Pages: e1000511
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Publication
- | J:94077
     
First Author: Mutant Mouse Regional Resource Centers
Year: 2004
Journal: Unpublished
Title: Information obtained from the Mutant Mouse Regional Resource Centers (MMRRC)
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Publication
15226823 | J:93300
First Author: Blackshaw S
Year: 2004
Journal: PLoS Biol
Title: Genomic analysis of mouse retinal development.
Volume: 2
Issue: 9
Pages: E247
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Publication
10725249 | J:60984
First Author: Ko MS
Year: 2000
Journal: Development
Title: Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development.
Volume: 127
Issue: 8
Pages: 1737-49
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Publication
12520002 | J:91812
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
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Publication
- | J:148605
     
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
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Publication
- | J:155845
     
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
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Publication
- | J:72247
       
First Author: DDB, FB, MGI, GOA, ZFIN curators
Year: 2001
Title: Gene Ontology annotation through association of InterPro records with GO terms
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Protein
Q91WG4-2
Organism: Mus musculus/domesticus
Length: 741  
Fragment?: false
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DO Term
DOID:0081220 | autosomal recessive intellectual developmental disorder 58
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Publication
8543574 | J:28634
First Author: Ninomiya Y
Year: 1995
Journal: J Biochem
Title: Genomic organization and isoforms of the mouse ELP gene.
Volume: 118
Issue: 2
Pages: 380-9
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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Cambridge CB2 3EH, United Kingdom