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Search results 1 to 100 out of 101 for Elp4

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Categories

Hits by Strain

Hits by Category

Type Details Score
Gene
26610 | ELP4
Type: gene
Organism: human
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Gene
687694 | Elp4
Type: gene
Organism: rat
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Gene
614139 | ELP4
Type: gene
Organism: cattle
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Gene
428603 | ELP4
Type: gene
Organism: chicken
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Gene
550331 | elp4
Type: gene
Organism: zebrafish
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Gene
695979 | ELP4
Type: gene
Organism: macaque, rhesus
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Gene
100485395 | elp4
Type: gene
Organism: frog, western clawed
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Gene
483442 | ELP4
Type: gene
Organism: dog, domestic
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Gene
451103 | ELP4
Type: gene
Organism: chimpanzee
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Protein Coding Gene
MGI:1925016 | Elp4
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein
Q3TRR1
Organism: Mus musculus/domesticus
Length: 66  
Fragment?: false
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Publication
11435442 | J:71291
First Author: Winkler GS
Year: 2001
Journal: J Biol Chem
Title: RNA polymerase II elongator holoenzyme is composed of two discrete subcomplexes.
Volume: 276
Issue: 35
Pages: 32743-9
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Protein Coding Gene
MGP_CAROLIEiJ_G0024038 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0026231 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0026192 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0026172 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0026201 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0025951 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_1925016 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0026652 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0025416 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0025929 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0026067 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0026030 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0026170 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0026054 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0026706 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0025151 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0025483 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0025476 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0024951 | -
Type: protein_coding_gene
Organism: Mus spretus
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GXD Expression
GXD Expression
     
Probe: MGI:4421795
Assay Type: Northern blot
Annotation Date: 2010-02-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2576528
Stage: TS28
Assay Id: MGI:4421796
Age: postnatal adult
Specimen Label: Adult
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:5634915
Assay Type: Western blot
Annotation Date: 2015-05-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754424
Stage: TS24
Assay Id: MGI:5635062
Age: embryonic day 16.0
Specimen Label: Cortex
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:5634915
Assay Type: Western blot
Annotation Date: 2015-05-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3266524
Stage: TS24
Assay Id: MGI:5635062
Age: embryonic day 16.0
Specimen Label: GE
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:6113929
Assay Type: RT-PCR
Annotation Date: 2018-02-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603919
Stage: TS19
Assay Id: MGI:6113936
Age: embryonic day 11.5
Image: 6
Specimen Label: WT E11.5
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
   
Probe: MGI:6113929
Assay Type: RT-PCR
Annotation Date: 2018-02-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603919
Stage: TS19
Assay Id: MGI:6113942
Age: embryonic day 11.5
Image: 6
Specimen Label: Pax6 -/- E11.5
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:6113929
Assay Type: RT-PCR
Annotation Date: 2018-02-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603919
Stage: TS19
Assay Id: MGI:6113942
Age: embryonic day 11.5
Image: 6
Specimen Label: Pax6 -/- E11.5
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:6113929
Assay Type: RT-PCR
Annotation Date: 2018-02-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603919
Stage: TS19
Assay Id: MGI:6113942
Age: embryonic day 11.5
Image: 6
Specimen Label: WT E11.5
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:6113929
Assay Type: RT-PCR
Annotation Date: 2018-02-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603919
Stage: TS19
Assay Id: MGI:6113942
Age: embryonic day 11.5
Image: 6
Specimen Label: WT E11.5
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
   
Probe: MGI:4421795
Assay Type: RNA in situ
Annotation Date: 2010-02-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1619820
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:4421799
Age: embryonic day 12.5
Specimen Label: Not shown
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:5634915
Assay Type: Immunohistochemistry
Annotation Date: 2015-05-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3271122
Pattern: Widespread
Stage: TS22
Assay Id: MGI:5635102
Age: embryonic day 14.5
Note: Expressed in all cells.
Specimen Label: 1S
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:5634915
Assay Type: Immunohistochemistry
Annotation Date: 2015-05-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3271122
Pattern: Widespread
Stage: TS22
Assay Id: MGI:5635102
Age: embryonic day 14.5
Specimen Label: 1T
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:5634915
Assay Type: Immunohistochemistry
Annotation Date: 2015-05-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3271222
Pattern: Widespread
Stage: TS22
Assay Id: MGI:5635102
Age: embryonic day 14.5
Note: Expressed in all cells.
Specimen Label: 1S
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:5634915
Assay Type: Immunohistochemistry
Annotation Date: 2015-05-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3271222
Pattern: Widespread
Stage: TS22
Assay Id: MGI:5635102
Age: embryonic day 14.5
Specimen Label: 1T
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:5634915
Assay Type: Immunohistochemistry
Annotation Date: 2015-05-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754422
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:5635102
Age: embryonic day 14.5
Note: Expressed in the cytoplasm.
Specimen Label: 1U/U'
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:4421795
Assay Type: RNA in situ
Annotation Date: 2010-02-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603917
Pattern: Ubiquitous
Stage: TS17
Assay Id: MGI:4421799
Age: embryonic day 10.5
Specimen Label: 2D
Detected: true
Specimen Num: 1
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Publication
19474196 | J:151902
First Author: Favor J
Year: 2009
Journal: Genetics
Title: Analysis of Pax6 contiguous gene deletions in the mouse, Mus musculus, identifies regions distinct from Pax6 responsible for extreme small-eye and belly-spotting phenotypes.
Volume: 182
Issue: 4
Pages: 1077-88
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Publication
14732405 | J:87754
First Author: Kleinjan DA
Year: 2004
Journal: Dev Biol
Title: Conserved elements in Pax6 intron 7 involved in (auto)regulation and alternative transcription.
Volume: 265
Issue: 2
Pages: 462-77
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Publication
19185337 | J:150477
First Author: Creppe C
Year: 2009
Journal: Cell
Title: Elongator controls the migration and differentiation of cortical neurons through acetylation of alpha-tubulin.
Volume: 136
Issue: 3
Pages: 551-64
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Publication
11889558 | J:72244
First Author: Kleinjan DA
Year: 2002
Journal: Mamm Genome
Title: Characterization of a novel gene adjacent to PAX6, revealing synteny conservation with functional significance.
Volume: 13
Issue: 2
Pages: 102-7
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Publication
33976153 | J:306113
First Author: Kojic M
Year: 2021
Journal: Nat Commun
Title: Elp2 mutations perturb the epitranscriptome and lead to a complex neurodevelopmental phenotype.
Volume: 12
Issue: 1
Pages: 2678
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Publication
16919269 | J:112701
First Author: Bailey PJ
Year: 2006
Journal: Exp Cell Res
Title: A global genomic transcriptional code associated with CNS-expressed genes.
Volume: 312
Issue: 16
Pages: 3108-19
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Publication
- | J:265051
     
First Author: MGI and IMPC
Year: 2018
Journal: Database Release
Title: MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC)
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Publication
- | J:155845
     
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
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Publication
- | J:157065
     
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Allele
Del(2)Pax6<12Neu> | MGI:3845767
 
Name: deletion, Chr 2, Neuherberg 12
Allele Type: Radiation induced
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Allele
Del(2)Pax6<13Neu> | MGI:3845753
 
Name: deletion, Chr 2, Neuherberg 13
Allele Type: Spontaneous
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Publication
19172991 | -
First Author: Strug LJ
Year: 2009
Journal: Eur J Hum Genet
Title: Centrotemporal sharp wave EEG trait in rolandic epilepsy maps to Elongator Protein Complex 4 (ELP4).
Volume: 17
Issue: 9
Pages: 1171-81
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Protein Domain
IPR008728 | Elongator_complex_protein_4
Type: Family
Description: Elongator is a 6 subunit protein complex highly conserved in eukaryotes. The human Elongator six-subunit complex, known as holo-Elongator, has histone acetyltransferase activity directed against histone H3 and H4 [, ]. It consists of two subcomplexes, a core subcomplex (ELP1-3), and an accessory subcomplex (ELP4-6) []. The elongator complex has been associated with many cellular activities, including transcriptional elongation [, ], but its main function is tRNA modification [, ]. It is required for the formation of 5-methoxy-carbonylmethyl (mcm5) and 5-carbamoylmethyl (ncm5) groups on uridine nucleosides present at the wobble position of many tRNAs [].This entry represents the ELP4 subunit. Mammalian ELP4 gene is implicated in rolandic epilepsy [].
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Allele
Del(2)Pax6<11Neu> | MGI:3845668
 
Name: deletion, Chr 2, Neuherberg 11
Allele Type: Spontaneous
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Genotype
Genotype
Symbol: Del(2)Pax6<11Neu>/+
Background: involves: 102 * C3H
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Del(2)Pax6<12Neu>/+
Background: involves: 102 * C3H
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Del(2)Pax6<13Neu>/+
Background: involves: 102 * C3H
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Del(2)Pax6<11Neu>/Del(2)Pax6<11Neu>
Background: involves: 102 * C3H
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Del(2)Pax6<12Neu>/Del(2)Pax6<12Neu>
Background: involves: 102 * C3H
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Del(2)Pax6<13Neu>/Del(2)Pax6<13Neu>
Background: involves: 102 * C3H
Zygosity: hm
Has Mutant Allele: true
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Protein
Q9ER73
Organism: Mus musculus/domesticus
Length: 422  
Fragment?: false
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Protein
A2A414
Organism: Mus musculus/domesticus
Length: 278  
Fragment?: true
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Publication
11904415 | -
First Author: Winkler GS
Year: 2002
Journal: Proc Natl Acad Sci U S A
Title: Elongator is a histone H3 and H4 acetyltransferase important for normal histone acetylation levels in vivo.
Volume: 99
Issue: 6
Pages: 3517-22
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Publication
11714725 | J:99828
First Author: Hawkes NA
Year: 2002
Journal: J Biol Chem
Title: Purification and characterization of the human elongator complex.
Volume: 277
Issue: 4
Pages: 3047-52
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Publication
22556426 | -
First Author: Lin Z
Year: 2012
Journal: J Biol Chem
Title: Crystal structure of elongator subcomplex Elp4-6.
Volume: 287
Issue: 25
Pages: 21501-8
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Publication
22854966 | J:187591
First Author: Close P
Year: 2012
Journal: J Biol Chem
Title: DERP6 (ELP5) and C3ORF75 (ELP6) regulate tumorigenicity and migration of melanoma cells as subunits of Elongator.
Volume: 287
Issue: 39
Pages: 32535-45
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Publication
10024884 | -
First Author: Otero G
Year: 1999
Journal: Mol Cell
Title: Elongator, a multisubunit component of a novel RNA polymerase II holoenzyme for transcriptional elongation.
Volume: 3
Issue: 1
Pages: 109-18
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Publication
11689709 | -
First Author: Krogan NJ
Year: 2001
Journal: Mol Cell Biol
Title: Characterization of a six-subunit holo-elongator complex required for the regulated expression of a group of genes in Saccharomyces cerevisiae.
Volume: 21
Issue: 23
Pages: 8203-12
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Publication
22889844 | -
First Author: Glatt S
Year: 2012
Journal: Transcription
Title: Elongator: transcriptional or translational regulator?
Volume: 3
Issue: 6
Pages: 273-6
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Publication
23165209 | -
First Author: Bauer F
Year: 2012
Journal: Cell Cycle
Title: A coordinated codon-dependent regulation of translation by Elongator.
Volume: 11
Issue: 24
Pages: 4524-9
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