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Search results 1 to 100 out of 107 for Emc3

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0.038s
Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: zebrafish
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: chimpanzee
Protein Domain
Type: Family
Description: EMC3 is a subunit if the ER Membrane protein Complex (EMC), which is required for efficient folding of proteins in the endoplasmic reticulum (ER). Loss of the EMC leads to accumulation of misfolded membrane proteins [].
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
GXD Expression
Probe: MGI:6456892
Assay Type: Immunohistochemistry
Annotation Date: 2023-01-23
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3286624
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:7427874
Age: embryonic day 16.5
Image: 1F Emc3 cKO
Note: Expression decreased in lung mesenchyme compared to control.
Specimen Label: 1F Emc3 cKO
Detected: true
Specimen Num: 4
GXD Expression
Probe: MGI:6456892
Assay Type: Immunohistochemistry
Annotation Date: 2023-01-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3286626
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:7427874
Age: embryonic day 18.5
Image: 1E Emc3 cKO
Note: Authors report expression partially recovered in lung mesenchyme at E18.5.
Specimen Label: 1E Emc3 cKO
Detected: true
Specimen Num: 2
Gene
Type: gene
Organism: human
Publication
First Author: Huang M
Year: 2021
Journal: Mucosal Immunol
Title: Emc3 maintains intestinal homeostasis by preserving secretory lineages.
Volume: 14
Issue: 4
Pages: 873-886
Publication
First Author: Tang X
Year: 2017
Journal: J Clin Invest
Title: EMC3 coordinates surfactant protein and lipid homeostasis required for respiration.
Volume: 127
Issue: 12
Pages: 4314-4325
Publication
First Author: Tang X
Year: 2023
Journal: iScience
Title: EMC3 regulates mesenchymal cell survival via control of the mitotic spindle assembly.
Volume: 26
Issue: 1
Pages: 105667
Publication
First Author: Zhu X
Year: 2020
Journal: PLoS One
Title: Loss of the ER membrane protein complex subunit Emc3 leads to retinal bipolar cell degeneration in aged mice.
Volume: 15
Issue: 9
Pages: e0238435
Publication
First Author: Cao X
Year: 2021
Journal: Invest Ophthalmol Vis Sci
Title: EMC3 Is Essential for Retinal Organization and Neurogenesis During Mouse Retinal Development.
Volume: 62
Issue: 2
Pages: 31
GXD Expression    
Probe: MGI:6456929
Assay Type: RT-PCR
Annotation Date: 2020-09-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672826
Stage: TS26
Assay Id: MGI:6456930
Age: embryonic day 18.5
Image: 1
Specimen Label: Whole lung Emc3 cKO
Detected: true
Specimen Num: 2
Protein
Organism: Mus musculus/domesticus
Length: 261  
Fragment?: false
Publication
First Author: Jonikas MC
Year: 2009
Journal: Science
Title: Comprehensive characterization of genes required for protein folding in the endoplasmic reticulum.
Volume: 323
Issue: 5922
Pages: 1693-7
GXD Expression
Probe: MGI:7427870
Assay Type: Immunohistochemistry
Annotation Date: 2023-01-23
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3286624
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:7427875
Age: embryonic day 16.5
Image: 1G Emc3 cKO
Note: Expression decreased in mesenchyme compared to control.
Specimen Label: 1G Emc3 cKO
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:7427870
Assay Type: Immunohistochemistry
Annotation Date: 2023-01-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3286624
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:7427876
Age: embryonic day 16.5
Image: 2A Emc3 cKO
Specimen Label: 2A Emc3 cKO
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:7427870
Assay Type: Immunohistochemistry
Annotation Date: 2023-01-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3286624
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:7427876
Age: embryonic day 16.5
Image: 2B Emc3 cKO
Specimen Label: 2B Emc3 cKO
Detected: true
Specimen Num: 4
GXD Expression
Probe: MGI:2179592
Assay Type: Immunohistochemistry
Annotation Date: 2023-01-23
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3286624
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:7427878
Age: embryonic day 16.5
Image: 2D Emc3 cKO
Note: Increased expression in mesenchyme compared to control.
Specimen Label: 2D Emc3 cKO
Detected: true
Specimen Num: 2
GXD Expression
Probe: MGI:6423143
Assay Type: Immunohistochemistry
Annotation Date: 2023-01-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3286624
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:7427879
Age: embryonic day 16.5
Image: S2A Emc3 cKO
Note: Expression similar to that of control.
Specimen Label: S2A Emc3 cKO
Detected: true
Specimen Num: 2
GXD Expression
Probe: MGI:7427873
Assay Type: Immunohistochemistry
Annotation Date: 2023-01-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3286624
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:7427880
Age: embryonic day 16.5
Image: S2B Emc3 cKO
Note: Expression similar to that of control.
Specimen Label: S2B Emc3 cKO
Detected: true
Specimen Num: 2
GXD Expression
Probe: MGI:7427870
Assay Type: Immunohistochemistry
Annotation Date: 2023-01-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3286024
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:7427875
Age: embryonic day 16.5
Image: 1G Emc3 cKO
Note: Expression persisted in respiratory epithelial cells.
Specimen Label: 1G Emc3 cKO
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:7427872
Assay Type: Immunohistochemistry
Annotation Date: 2023-01-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3286024
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:7427877
Age: embryonic day 16.5
Image: 2A Emc3 cKO
Specimen Label: 2A Emc3 cKO
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:7427872
Assay Type: Immunohistochemistry
Annotation Date: 2023-01-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3286024
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:7427877
Age: embryonic day 16.5
Image: 2B Emc3 cKO
Specimen Label: 2B Emc3 cKO
Detected: true
Specimen Num: 4
GXD Expression
Probe: MGI:6423143
Assay Type: Immunohistochemistry
Annotation Date: 2023-01-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3286024
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:7427879
Age: embryonic day 16.5
Image: S2A Emc3 cKO
Note: Expression similar to that of control.
Specimen Label: S2A Emc3 cKO
Detected: true
Specimen Num: 2
GXD Expression
Probe: MGI:7427873
Assay Type: Immunohistochemistry
Annotation Date: 2023-01-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3286024
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:7427880
Age: embryonic day 16.5
Image: S2B Emc3 cKO
Note: Expression similar to that of control.
Specimen Label: S2B Emc3 cKO
Detected: true
Specimen Num: 2
Publication      
First Author: Xiong L
Year: 2019
Journal: Cell Death Differ
Title: ER complex proteins are required for rhodopsin biosynthesis and photoreceptor survival in Drosophila and mice.
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
GXD Expression    
Probe: MGI:6456929
Assay Type: RT-PCR
Annotation Date: 2020-09-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672826
Stage: TS26
Assay Id: MGI:6456930
Age: embryonic day 18.5
Image: 1
Specimen Label: Whole lung Control
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:6456889
Assay Type: Western blot
Annotation Date: 2020-09-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672826
Stage: TS26
Assay Id: MGI:6456972
Age: embryonic day 18.5
Image: 1
Specimen Label: +/+
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:6456889
Assay Type: Western blot
Annotation Date: 2020-09-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672826
Stage: TS26
Assay Id: MGI:6456972
Age: embryonic day 18.5
Image: 1
Specimen Label: +/+
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:6456889
Assay Type: Western blot
Annotation Date: 2020-09-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672826
Stage: TS26
Assay Id: MGI:6456972
Age: embryonic day 18.5
Image: 1
Specimen Label: +/+
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:6456889
Assay Type: Western blot
Annotation Date: 2020-09-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672826
Stage: TS26
Assay Id: MGI:6456972
Age: embryonic day 18.5
Image: 1
Specimen Label: +/-
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:6456889
Assay Type: Western blot
Annotation Date: 2020-09-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672826
Stage: TS26
Assay Id: MGI:6456972
Age: embryonic day 18.5
Image: 1
Specimen Label: +/-
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:6456889
Assay Type: Western blot
Annotation Date: 2020-09-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672826
Stage: TS26
Assay Id: MGI:6456972
Age: embryonic day 18.5
Image: 1
Specimen Label: +/-
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:6456889
Assay Type: Western blot
Annotation Date: 2020-09-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672826
Stage: TS26
Assay Id: MGI:6456972
Age: embryonic day 18.5
Image: 1
Specimen Label: -/-
Detected: true
Specimen Num: 7
GXD Expression    
Probe: MGI:6456889
Assay Type: Western blot
Annotation Date: 2020-09-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672826
Stage: TS26
Assay Id: MGI:6456972
Age: embryonic day 18.5
Image: 1
Specimen Label: -/-
Detected: true
Specimen Num: 8
GXD Expression    
Probe: MGI:6456889
Assay Type: Western blot
Annotation Date: 2020-09-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672826
Stage: TS26
Assay Id: MGI:6456972
Age: embryonic day 18.5
Image: 1
Specimen Label: -/-
Detected: true
Specimen Num: 9
GXD Expression
Probe: MGI:6456892
Assay Type: Immunohistochemistry
Annotation Date: 2023-01-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3286626
Pattern: Widespread
Stage: TS26
Assay Id: MGI:7427874
Age: embryonic day 18.5
Image: 1E control
Note: Widespread expression in epithelial and mesenchymal cells.
Specimen Label: 1E control
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:6456892
Assay Type: Immunohistochemistry
Annotation Date: 2023-01-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3286624
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:7427874
Age: embryonic day 16.5
Image: 1F control
Specimen Label: 1F control
Detected: true
Specimen Num: 3
GXD Expression
Probe: MGI:6456892
Assay Type: Immunohistochemistry
Annotation Date: 2023-01-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3286026
Pattern: Widespread
Stage: TS26
Assay Id: MGI:7427874
Age: embryonic day 18.5
Image: 1E control
Note: Widespread expression in epithelial and mesenchymal cells.
Specimen Label: 1E control
Detected: true
Specimen Num: 1
Publication
First Author: Guna A
Year: 2018
Journal: Science
Title: The ER membrane protein complex is a transmembrane domain insertase.
Volume: 359
Issue: 6374
Pages: 470-473
Publication      
First Author: The UK Mouse Genome Centre European Consortium
Year: 2000
Journal: Database Release
Title: European Consortium EST Radiation Hybrid Database
Publication        
First Author: Birgit Meldal and Sandra Orchard (1). (1) European Bioinformatics Institute (EBI), Hinxton, Cambridgeshire, United Kingdom
Year: 2023
Title: Manual transfer of experimentally-verified manual GO annotation data to homologous complexes by curator judgment of sequence, composition and function similarity
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2023
Title: TreeGrafter-generated GO annotations
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations for FANTOM2 data
Publication
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
Publication      
First Author: International Knockout Mouse Consortium
Year: 2014
Journal: Database Download
Title: MGI download of modified allele data from IKMC and creation of new knockout alleles
Publication      
First Author: Lennon G
Year: 1999
Journal: Database Download
Title: WashU-HHMI Mouse EST Project
Publication      
First Author: Velocigene
Year: 2008
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals)
Publication      
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
Publication      
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
Publication        
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
Publication      
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
Publication
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
Publication
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
Publication        
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
Publication      
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
Publication
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
Publication
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
Publication        
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
Publication      
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
Publication
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication      
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication        
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load