Type |
Details |
Score |
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
frog, western clawed |
|
•
•
•
•
•
|
Gene |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
dog, domestic |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chimpanzee |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
cattle |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chicken |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
macaque, rhesus |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Family |
Description: |
ER membrane protein complex subunit 7 (EMC7) is a component of the endoplasmic reticulum membrane protein complex (EMC). This complex was first found to interact with the degradation of misfolded proteins by the ubiquitin- and proteasome-dependent process known as ER-associated degradation (ERAD) [], thus suggesting a role in the biosynthesis of transmembrane proteins. More recently, it was shown that EMC acts as a conserved co- and post-translational insertase at the endoplasmic reticulum in an energy-independent manner [, ]. EMC7 has been misnamed C11orf3, but is more correctly named C15orf24 because the gene is actually on human chromosome 15. |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Publication |
First Author: |
Xiong L |
Year: |
2019 |
Journal: |
Cell Death Differ |
Title: |
ER complex proteins are required for rhodopsin biosynthesis and photoreceptor survival in Drosophila and mice. |
|
|
|
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
241
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
241
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Christianson JC |
Year: |
2011 |
Journal: |
Nat Cell Biol |
Title: |
Defining human ERAD networks through an integrative mapping strategy. |
Volume: |
14 |
Issue: |
1 |
Pages: |
93-105 |
|
•
•
•
•
•
|
Publication |
First Author: |
Pleiner T |
Year: |
2020 |
Journal: |
Science |
Title: |
Structural basis for membrane insertion by the human ER membrane protein complex. |
Volume: |
369 |
Issue: |
6502 |
Pages: |
433-436 |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus caroli |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus pahari |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus spretus |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6456899 |
Assay Type: |
Western blot |
Annotation Date: |
2020-09-24 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1672826 |
|
Stage: |
TS26 |
Assay Id: |
MGI:6456979 |
Age: |
embryonic day 18.5 |
Image: |
1 |
|
Specimen Label: |
+/+ |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6456899 |
Assay Type: |
Western blot |
Annotation Date: |
2020-09-24 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1672826 |
|
Stage: |
TS26 |
Assay Id: |
MGI:6456979 |
Age: |
embryonic day 18.5 |
Image: |
1 |
|
Specimen Label: |
+/+ |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6456899 |
Assay Type: |
Western blot |
Annotation Date: |
2020-09-24 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1672826 |
|
Stage: |
TS26 |
Assay Id: |
MGI:6456979 |
Age: |
embryonic day 18.5 |
Image: |
1 |
|
Specimen Label: |
+/+ |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6456899 |
Assay Type: |
Western blot |
Annotation Date: |
2020-09-24 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1672826 |
|
Stage: |
TS26 |
Assay Id: |
MGI:6456979 |
Age: |
embryonic day 18.5 |
Image: |
1 |
|
Specimen Label: |
+/- |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6456899 |
Assay Type: |
Western blot |
Annotation Date: |
2020-09-24 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1672826 |
|
Stage: |
TS26 |
Assay Id: |
MGI:6456979 |
Age: |
embryonic day 18.5 |
Image: |
1 |
|
Specimen Label: |
+/- |
Detected: |
true |
Specimen Num: |
5 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6456899 |
Assay Type: |
Western blot |
Annotation Date: |
2020-09-24 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1672826 |
|
Stage: |
TS26 |
Assay Id: |
MGI:6456979 |
Age: |
embryonic day 18.5 |
Image: |
1 |
|
Specimen Label: |
+/- |
Detected: |
true |
Specimen Num: |
6 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6456899 |
Assay Type: |
Western blot |
Annotation Date: |
2020-09-24 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1672826 |
|
Stage: |
TS26 |
Assay Id: |
MGI:6456979 |
Age: |
embryonic day 18.5 |
Image: |
1 |
|
Specimen Label: |
-/- |
Detected: |
true |
Specimen Num: |
7 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6456899 |
Assay Type: |
Western blot |
Annotation Date: |
2020-09-24 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1672826 |
|
Stage: |
TS26 |
Assay Id: |
MGI:6456979 |
Age: |
embryonic day 18.5 |
Image: |
1 |
|
Specimen Label: |
-/- |
Detected: |
true |
Specimen Num: |
8 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6456899 |
Assay Type: |
Western blot |
Annotation Date: |
2020-09-24 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1672826 |
|
Stage: |
TS26 |
Assay Id: |
MGI:6456979 |
Age: |
embryonic day 18.5 |
Image: |
1 |
|
Specimen Label: |
-/- |
Detected: |
true |
Specimen Num: |
9 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3584584 |
Assay Type: |
RNA in situ |
Annotation Date: |
2005-08-30 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1915528 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:3585809 |
Age: |
postnatal day 6-7 |
Image: |
P6/7 |
|
Specimen Label: |
P6/7 |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3584584 |
Assay Type: |
RNA in situ |
Annotation Date: |
2005-08-30 |
Strength: |
Weak |
Sex: |
Not Specified |
Emaps: |
EMAPS:1915528 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:3585809 |
Age: |
postnatal day 8-10 |
Image: |
P8/10 |
|
Specimen Label: |
P8/10 |
Detected: |
true |
Specimen Num: |
5 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3584584 |
Assay Type: |
RNA in situ |
Annotation Date: |
2005-08-30 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3598824 |
Pattern: |
Not Specified |
Stage: |
TS24 |
Assay Id: |
MGI:3585809 |
Age: |
embryonic day 16.0 |
|
|
Specimen Label: |
Embryo |
Detected: |
true |
Specimen Num: |
8 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3584584 |
Assay Type: |
RNA in situ |
Annotation Date: |
2005-08-30 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1647028 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:3585809 |
Age: |
postnatal day 6 |
|
Note: |
Expression was widespread. |
Specimen Label: |
CNS |
Detected: |
true |
Specimen Num: |
7 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3584584 |
Assay Type: |
RNA in situ |
Annotation Date: |
2005-08-30 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1915727 |
Pattern: |
Not Specified |
Stage: |
TS27 |
Assay Id: |
MGI:3585809 |
Age: |
postnatal day 2-3 |
|
Note: |
Expression was detected in the outer neuroblastic layer. |
Specimen Label: |
P2/3 |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3584584 |
Assay Type: |
RNA in situ |
Annotation Date: |
2005-08-30 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1915728 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:3585809 |
Age: |
postnatal day 4-5 |
Image: |
P4/5 |
Note: |
Expression was detected in the outer neuroblastic layer. |
Specimen Label: |
P4/5 |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3584584 |
Assay Type: |
RNA in situ |
Annotation Date: |
2005-08-30 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1915728 |
Pattern: |
Regionally restricted |
Stage: |
TS28 |
Assay Id: |
MGI:3585809 |
Age: |
postnatal day 6-7 |
Image: |
P6/7 |
Note: |
Expression was detected in the inner segment. |
Specimen Label: |
P6/7 |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3584584 |
Assay Type: |
RNA in situ |
Annotation Date: |
2005-08-30 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1915728 |
Pattern: |
Regionally restricted |
Stage: |
TS28 |
Assay Id: |
MGI:3585809 |
Age: |
postnatal day 8-10 |
Image: |
P8/10 |
Note: |
Expression was detected in the inner segment. |
Specimen Label: |
P8/10 |
Detected: |
true |
Specimen Num: |
5 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3584584 |
Assay Type: |
RNA in situ |
Annotation Date: |
2005-08-30 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1915728 |
Pattern: |
Regionally restricted |
Stage: |
TS28 |
Assay Id: |
MGI:3585809 |
Age: |
postnatal adult |
|
Note: |
Expression was detected in the inner segment. |
Specimen Label: |
Adult |
Detected: |
true |
Specimen Num: |
6 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3584584 |
Assay Type: |
RNA in situ |
Annotation Date: |
2005-08-30 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1684624 |
Pattern: |
Not Specified |
Stage: |
TS24 |
Assay Id: |
MGI:3585809 |
Age: |
embryonic day 16.0 |
|
|
Specimen Label: |
Embryo |
Detected: |
true |
Specimen Num: |
8 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3584584 |
Assay Type: |
RNA in situ |
Annotation Date: |
2005-08-30 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1859224 |
Pattern: |
Regionally restricted |
Stage: |
TS24 |
Assay Id: |
MGI:3585809 |
Age: |
embryonic day 16.0 |
Image: |
E16 |
Note: |
Expression was detected in the outer neuroblastic layer and the scleral inner neuroblastic layer. The expression level was higher in the scleral inner neuroblastic layer. |
Specimen Label: |
E16 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
Publication |
First Author: |
O'Brien KP |
Year: |
2000 |
Journal: |
Biochem Biophys Res Commun |
Title: |
Characterization of five novel human genes in the 11q13-q22 region. |
Volume: |
273 |
Issue: |
1 |
Pages: |
90-4 |
|
•
•
•
•
•
|
Publication |
First Author: |
Guna A |
Year: |
2018 |
Journal: |
Science |
Title: |
The ER membrane protein complex is a transmembrane domain insertase. |
Volume: |
359 |
Issue: |
6374 |
Pages: |
470-473 |
|
•
•
•
•
•
|
Publication |
First Author: |
Tang X |
Year: |
2017 |
Journal: |
J Clin Invest |
Title: |
EMC3 coordinates surfactant protein and lipid homeostasis required for respiration. |
Volume: |
127 |
Issue: |
12 |
Pages: |
4314-4325 |
|
•
•
•
•
•
|
Publication |
First Author: |
Tang T |
Year: |
2010 |
Journal: |
Nat Biotechnol |
Title: |
A mouse knockout library for secreted and transmembrane proteins. |
Volume: |
28 |
Issue: |
7 |
Pages: |
749-55 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lexicon Genetics, Inc |
Year: |
2011 |
Journal: |
Database Download |
Title: |
MGI download of Lexicon knockout data |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Birgit Meldal and Sandra Orchard (1). (1) European Bioinformatics Institute (EBI), Hinxton, Cambridgeshire, United Kingdom |
Year: |
2023 |
|
Title: |
Manual transfer of experimentally-verified manual GO annotation data to homologous complexes by curator judgment of sequence, composition and function similarity |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Blackshaw S |
Year: |
2004 |
Journal: |
PLoS Biol |
Title: |
Genomic analysis of mouse retinal development. |
Volume: |
2 |
Issue: |
9 |
Pages: |
E247 |
|
•
•
•
•
•
|
Publication |
First Author: |
University of California, Davis |
Year: |
2010 |
Journal: |
MGI Direct Data Submission |
Title: |
Alleles produced for the KOMP project by the University of California, Davis |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2002 |
|
Title: |
Mouse Genome Informatics Computational Sequence to Gene Associations for FANTOM2 data |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Stryke D |
Year: |
2003 |
Journal: |
Nucleic Acids Res |
Title: |
BayGenomics: a resource of insertional mutations in mouse embryonic stem cells. |
Volume: |
31 |
Issue: |
1 |
Pages: |
278-81 |
|
•
•
•
•
•
|
Publication |
First Author: |
International Knockout Mouse Consortium |
Year: |
2014 |
Journal: |
Database Download |
Title: |
MGI download of modified allele data from IKMC and creation of new knockout alleles |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC) |
Year: |
2014 |
Journal: |
Database Release |
Title: |
Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
DDB, FB, MGI, GOA, ZFIN curators |
Year: |
2001 |
|
Title: |
Gene Ontology annotation through association of InterPro records with GO terms |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2003 |
|
Title: |
MGI Sequence Curation Reference |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2002 |
|
Title: |
Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Kawai J |
Year: |
2001 |
Journal: |
Nature |
Title: |
Functional annotation of a full-length mouse cDNA collection. |
Volume: |
409 |
Issue: |
6821 |
Pages: |
685-90 |
|
•
•
•
•
•
|
Publication |
First Author: |
MGD Nomenclature Committee |
Year: |
1995 |
|
Title: |
Nomenclature Committee Use |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI) |
Year: |
2008 |
Journal: |
Database Download |
Title: |
Mouse Gene Trap Data Load from dbGSS |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators |
Year: |
2011 |
|
Title: |
Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
The Jackson Laboratory Mouse Radiation Hybrid Database |
Year: |
2004 |
Journal: |
Database Release |
Title: |
Mouse T31 Radiation Hybrid Data Load |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Okazaki Y |
Year: |
2002 |
Journal: |
Nature |
Title: |
Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. |
Volume: |
420 |
Issue: |
6915 |
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563-73 |
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First Author: |
The Gene Ontology Consortium |
Year: |
2010 |
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Title: |
Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs |
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First Author: |
Diez-Roux G |
Year: |
2011 |
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PLoS Biol |
Title: |
A high-resolution anatomical atlas of the transcriptome in the mouse embryo. |
Volume: |
9 |
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1 |
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e1000582 |
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First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2002 |
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Title: |
Mouse Genome Informatics Computational Sequence to Gene Associations |
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First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2010 |
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Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2). |
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First Author: |
Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas |
Year: |
2010 |
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Title: |
Annotation inferences using phylogenetic trees |
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First Author: |
Mouse Genome Database and National Center for Biotechnology Information |
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2000 |
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Database Release |
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Entrez Gene Load |
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First Author: |
Allen Institute for Brain Science |
Year: |
2004 |
Journal: |
Allen Institute |
Title: |
Allen Brain Atlas: mouse riboprobes |
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First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
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Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform |
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First Author: |
Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI) |
Year: |
2010 |
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Database Download |
Title: |
Consensus CDS project |
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First Author: |
Mouse Genome Informatics Group |
Year: |
2003 |
Journal: |
Database Procedure |
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First Author: |
Bairoch A |
Year: |
1999 |
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Title: |
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
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Title: |
Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations |
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First Author: |
Mouse Genome Informatics |
Year: |
2010 |
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Title: |
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First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
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Title: |
Obtaining and loading genome assembly coordinates from NCBI annotations |
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
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Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform |
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