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Search results 1 to 71 out of 71 for Eme2

0.033s
Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: chimpanzee
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: zebrafish
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
GXD Expression      
Probe: MGI:7522138
Assay Type: RT-PCR
Annotation Date: 2023-08-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3747121
Stage: TS21
Assay Id: MGI:7522325
Age: embryonic day 13.5
Specimen Label: Evf2+/+
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:7522138
Assay Type: RT-PCR
Annotation Date: 2023-08-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3747121
Stage: TS21
Assay Id: MGI:7522325
Age: embryonic day 13.5
Specimen Label: Evf2TS/TS
Detected: true
Specimen Num: 2
Publication
First Author: Ciccia A
Year: 2007
Journal: Mol Cell
Title: Identification of FAAP24, a Fanconi anemia core complex protein that interacts with FANCM.
Volume: 25
Issue: 3
Pages: 331-43
Publication
First Author: Simonson L
Year: 2020
Journal: Dev Biol
Title: Keratin 13 deficiency causes white sponge nevus in mice.
Volume: 468
Issue: 1-2
Pages: 146-153
Publication
First Author: Cajigas I
Year: 2018
Journal: Mol Cell
Title: The Evf2 Ultraconserved Enhancer lncRNA Functionally and Spatially Organizes Megabase Distant Genes in the Developing Forebrain.
Volume: 71
Issue: 6
Pages: 956-972.e9
Publication        
First Author: Birgit Meldal and Sandra Orchard (1). (1) European Bioinformatics Institute (EBI), Hinxton, Cambridgeshire, United Kingdom
Year: 2023
Title: Manual transfer of experimentally-verified manual GO annotation data to homologous complexes by curator judgment of sequence, composition and function similarity
Publication      
First Author: University of California, Davis
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the University of California, Davis
Publication      
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
Publication
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
Publication
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication        
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Gene
Type: gene
Organism: rat
UniProt Feature
Begin: 1
Description: Probable crossover junction endonuclease EME2
Type: chain
End: 373
Protein
Organism: Mus musculus/domesticus
Length: 373  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 352  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 72  
Fragment?: false
Protein Domain
Type: Family
Description: Budding yeast Mus81 complexes with Mms4 (EME1 or EME2 in humans) to form a structure-specific endonuclease that targets branched DNA structures with a 5'-end at the branch nick [, ]. Its typical substrates include 3'-flap structures, replication forks and nicked Holliday junctions [, ].Similar to MUS81-EME1, human MUS81-EME2 cleaves 3'-flaps, replication forks and nicked Holliday junctions, and exhibits limited endonuclease activity with intact Holliday junctions. However, MUS81-EME2 can also cleave a variety of DNA structures including D-loop recombination intermediates and nicked duplex [, ].
Protein
Organism: Mus musculus/domesticus
Length: 130  
Fragment?: true
Publication
First Author: Fu Y
Year: 2003
Journal: DNA Repair (Amst)
Title: Functional domains required for the Saccharomyces cerevisiae Mus81-Mms4 endonuclease complex formation and nuclear localization.
Volume: 2
Issue: 12
Pages: 1435-47
Publication
First Author: Gaskell LJ
Year: 2007
Journal: EMBO J
Title: Mus81 cleavage of Holliday junctions: a failsafe for processing meiotic recombination intermediates?
Volume: 26
Issue: 7
Pages: 1891-901
Publication
First Author: Mayle R
Year: 2015
Journal: Science
Title: DNA REPAIR. Mus81 and converging forks limit the mutagenicity of replication fork breakage.
Volume: 349
Issue: 6249
Pages: 742-7
Publication
First Author: Shin YK
Year: 2012
Journal: FEBS J
Title: Human MUS81 complexes stimulate flap endonuclease 1.
Volume: 279
Issue: 13
Pages: 2412-30
Publication
First Author: Pepe A
Year: 2014
Journal: Nucleic Acids Res
Title: Substrate specificity of the MUS81-EME2 structure selective endonuclease.
Volume: 42
Issue: 6
Pages: 3833-45
Publication
First Author: Amangyeld T
Year: 2014
Journal: Nucleic Acids Res
Title: Human MUS81-EME2 can cleave a variety of DNA structures including intact Holliday junction and nicked duplex.
Volume: 42
Issue: 9
Pages: 5846-62
Protein
Organism: Mus musculus/domesticus
Length: 551  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 502  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 389  
Fragment?: true
Publication
First Author: Gerhard DS
Year: 2004
Journal: Genome Res
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Volume: 14
Issue: 10B
Pages: 2121-7
Publication
First Author: Church DM
Year: 2009
Journal: PLoS Biol
Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.
Volume: 7
Issue: 5
Pages: e1000112