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Search results 1 to 100 out of 117 for Endou

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Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: zebrafish
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: chimpanzee
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Domain
Type: Family
Description: The founding member of this family, XendoU, is a uridylate-specific, divalent cation-dependent enzyme that produces molecules with 2',3'-cyclic phosphate ends [, ]. The human Endou, known as PP11, has endoribonuclease activity with placental tissue specificity [, ].
Publication
First Author: Poe JC
Year: 2014
Journal: J Exp Med
Title: EndoU is a novel regulator of AICD during peripheral B cell selection.
Volume: 211
Issue: 1
Pages: 57-69
Publication  
First Author: Lee HC
Year: 2017
Journal: Gene Expr Patterns
Title: Embryonic expression patterns of Eukaryotic EndoU ribonuclease family gene endouC in zebrafish.
Volume: 25-26
Pages: 66-70
Protein
Organism: Mus musculus/domesticus
Length: 412  
Fragment?: false
Publication
First Author: Renzi F
Year: 2006
Journal: Proc Natl Acad Sci U S A
Title: The structure of the endoribonuclease XendoU: From small nucleolar RNA processing to severe acute respiratory syndrome coronavirus replication.
Volume: 103
Issue: 33
Pages: 12365-70
Publication
First Author: Laneve P
Year: 2008
Journal: J Biol Chem
Title: The tumor marker human placental protein 11 is an endoribonuclease.
Volume: 283
Issue: 50
Pages: 34712-9
Publication
First Author: Gioia U
Year: 2005
Journal: J Biol Chem
Title: Functional characterization of XendoU, the endoribonuclease involved in small nucleolar RNA biosynthesis.
Volume: 280
Issue: 19
Pages: 18996-9002
Publication
First Author: Endou M
Year: 1994
Journal: J Pharmacol Exp Ther
Title: Histamine H3-receptor signaling in the heart: possible involvement of Gi/Go proteins and N-type Ca++ channels.
Volume: 269
Issue: 1
Pages: 221-9
Publication
First Author: Mushegian A
Year: 2020
Journal: RNA
Title: An ancient evolutionary connection between Ribonuclease A and EndoU families.
Volume: 26
Issue: 7
Pages: 803-813
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Baughman G
Year: 1992
Journal: J Immunol
Title: Tcl-30, a new T cell-specific gene expressed in immature glucocorticoid-sensitive thymocytes.
Volume: 149
Issue: 5
Pages: 1488-96
GXD Expression    
Probe: MGI:6434213
Assay Type: RT-PCR
Annotation Date: 2020-06-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3187817
Stage: TS17
Assay Id: MGI:6434496
Age: embryonic day 10.5
Image: S4
Specimen Label: WT
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:6434213
Assay Type: RT-PCR
Annotation Date: 2020-06-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3187817
Stage: TS17
Assay Id: MGI:6434496
Age: embryonic day 10.5
Image: S4
Specimen Label: KO
Detected: true
Specimen Num: 2
GXD Expression  
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1737328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6693188
Age: postnatal adult
Image: UC Davis_1881302
Note: kidney
Specimen Label: UC Davis_1881302
Detected: true
Specimen Num: 2
GXD Expression  
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1737328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6693188
Age: postnatal adult
Image: UC Davis_1881303
Note: kidney
Specimen Label: UC Davis_1881303
Detected: true
Specimen Num: 3
GXD Expression  
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1737328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6693188
Age: postnatal adult
Image: UC Davis_1881304
Note: kidney
Specimen Label: UC Davis_1881304
Detected: true
Specimen Num: 4
GXD Expression  
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1737328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6693188
Age: postnatal adult
Image: UC Davis_1881295
Note: kidney
Specimen Label: UC Davis_1881295
Detected: true
Specimen Num: 5
GXD Expression  
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1737328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6693188
Age: postnatal adult
Image: UC Davis_1881296
Note: kidney
Specimen Label: UC Davis_1881296
Detected: true
Specimen Num: 6
GXD Expression  
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1737328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6693188
Age: postnatal adult
Image: UC Davis_1881297
Note: kidney
Specimen Label: UC Davis_1881297
Detected: true
Specimen Num: 7
GXD Expression  
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1868128
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6693188
Age: postnatal adult
Image: UC Davis_1881300
Note: vas deferens
Specimen Label: UC Davis_1881300
Detected: true
Specimen Num: 10
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6693188
Age: postnatal adult
Image: UC Davis_1881298
Specimen Label: UC Davis_1881298
Detected: true
Specimen Num: 8
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1929028
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6693188
Age: postnatal adult
Image: UC Davis_1881299
Specimen Label: UC Davis_1881299
Detected: true
Specimen Num: 9
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:3276428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6693188
Age: postnatal adult
Image: UC Davis_1881301
Specimen Label: UC Davis_1881301
Detected: true
Specimen Num: 1
Publication
First Author: Jia F
Year: 2020
Journal: Cell Rep
Title: Regulation of Nucleotide Metabolism and Germline Proliferation in Response to Nucleotide Imbalance and Genotoxic Stresses by EndoU Nuclease.
Volume: 30
Issue: 6
Pages: 1848-1861.e5
Publication
First Author: Kingsmore SF
Year: 1993
Journal: Mamm Genome
Title: Genetic mapping of Pp11r, a thymocyte gene expressed during apoptosis, to mouse chromosome 15.
Volume: 4
Issue: 8
Pages: 459-60
Publication
First Author: Baughman G
Year: 1991
Journal: Mol Endocrinol
Title: Genes newly identified as regulated by glucocorticoids in murine thymocytes.
Volume: 5
Issue: 5
Pages: 637-44
Publication
First Author: Michalska K
Year: 2018
Journal: Mol Microbiol
Title: Functional plasticity of antibacterial EndoU toxins.
Volume: 109
Issue: 4
Pages: 509-527
Publication
First Author: Paikari A
Year: 2017
Journal: Development
Title: The eutheria-specific miR-290 cluster modulates placental growth and maternal-fetal transport.
Volume: 144
Issue: 20
Pages: 3731-3743
Publication
First Author: Ingham NJ
Year: 2019
Journal: PLoS Biol
Title: Mouse screen reveals multiple new genes underlying mouse and human hearing loss.
Volume: 17
Issue: 4
Pages: e3000194
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2016
Title: Automatic assignment of GO terms using logical inference, based on on inter-ontology links
Publication
First Author: Koscielny G
Year: 2014
Journal: Nucleic Acids Res
Title: The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data.
Volume: 42
Issue: Database issue
Pages: D802-9
Publication      
First Author: International Knockout Mouse Consortium
Year: 2014
Journal: Database Download
Title: MGI download of modified allele data from IKMC and creation of new knockout alleles
Publication      
First Author: Velocigene
Year: 2008
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals)
Publication      
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
Publication        
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
Publication      
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
Publication        
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
Publication        
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
Publication        
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
Publication        
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2000
Title: Gene Ontology Annotation by electronic association of SwissProt Keywords with GO terms
Publication        
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
Publication      
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
Publication
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication      
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
Publication        
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Protein Domain
Type: Domain
Description: This EndoU nuclease domain is a bacterial version eukaryotic EndoU nuclease. It is found at the C-terminal region of polymorphic toxin proteins [, ]. Nucleases are widely used as toxins for defense, offense or addiction of selfish elements.
Publication
First Author: Schwarz DS
Year: 2014
Journal: J Cell Biol
Title: The calcium-dependent ribonuclease XendoU promotes ER network formation through local RNA degradation.
Volume: 207
Issue: 1
Pages: 41-57
Publication  
First Author: Laneve P
Year: 2017
Journal: Sci Rep
Title: Drosophila CG3303 is an essential endoribonuclease linked to TDP-43-mediated neurodegeneration.
Volume: 7
Pages: 41559
Publication
First Author: Ragno R
Year: 2011
Journal: ChemMedChem
Title: Identification of small-molecule inhibitors of the XendoU endoribonucleases family.
Volume: 6
Issue: 10
Pages: 1797-805
Protein Domain
Type: Domain
Description: This entry represents the EndoU domain found at the C-terminal of EndoU endoribonucleases, which carries out a conserved RNA processing function. The EndoU domain cleaves RNA at uridylates and release 2',3'-cyclic phosphodiester ends. The EndoU domain is an α/β domain, that contains nine α-helices and three antiparallel β-sheets; the latter are clustered on one side of the domain, whereas the α-helices are largely on the other side []. It contains a conserved trio of catalytic residues, two histidines and a lysine.EndoU is a family of metal-dependent endoribonucleases that is broadly conserved among eukaryotes [, ]. EndoU family members have RNA-binding and endoribonuclease activities and appear to be involved in many aspects ofbiology, including small nucleolar RNA biogenesis, endoplasmic reticulum (ER) network formation, immune response, and neurodegeneration:Xenopus laevis endoribonuclease XendoU is responsible for processing the intron encoded U16 and U86 small nucleolar RNAs (snoRNAs) [, , ].Human EndoU, also known as PP11 (placental protein 11), has an endoribonuclease activity with placental tissue specificity [, , ].Drosophila melanogaster CG2145 and DendoU endoribonucleases [].Caenorhabditis elegans endu-2 regulates nucleotide metabolism and germ cell proliferation in response to nucleotide imbalance and other genotoxic stress [].
Author
Author
Publication
First Author: Utsunomiya-Tate N
Year: 1996
Journal: J Biol Chem
Title: Cloning and functional characterization of a system ASC-like Na+-dependent neutral amino acid transporter.
Volume: 271
Issue: 25
Pages: 14883-90
Publication
First Author: Utsunomiya-Tate N
Year: 1997
Journal: FEBS Lett
Title: Tissue specific variants of glutamate transporter GLT-1.
Volume: 416
Issue: 3
Pages: 312-6
Publication
First Author: Sekine T
Year: 2006
Journal: Am J Physiol Renal Physiol
Title: Molecular physiology of renal organic anion transporters.
Volume: 290
Issue: 2
Pages: F251-61
Publication
First Author: Hosoyamada M
Year: 2004
Journal: J Am Soc Nephrol
Title: Function and localization of urate transporter 1 in mouse kidney.
Volume: 15
Issue: 2
Pages: 261-8
Publication
First Author: Yanai K
Year: 1998
Journal: Life Sci
Title: Targeting disruption of histamine H1 receptors in mice: behavioral and neurochemical characterization.
Volume: 62
Issue: 17-18
Pages: 1607-10
Publication
First Author: Hosoyamada M
Year: 1999
Journal: Am J Physiol
Title: Molecular cloning and functional expression of a multispecific organic anion transporter from human kidney.
Volume: 276
Issue: 1 Pt 2
Pages: F122-8