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Search results 1 to 100 out of 902 for Epas1

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0.037s
Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: chimpanzee
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
GXD Expression  
Probe: MGI:3506258
Assay Type: RNA in situ
Annotation Date: 2021-03-30
Strength: Present
Sex: Female
Emaps: EMAPS:3152723
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:6513163
Age: embryonic day 15.5
Image: 5 - Epas1
Specimen Label: 5 - Epas1
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:3506258
Assay Type: RNA in situ
Annotation Date: 2021-03-30
Strength: Present
Sex: Female
Emaps: EMAPS:3607823
Pattern: Widespread
Stage: TS23
Assay Id: MGI:6513163
Age: embryonic day 15.5
Image: 5 - Epas1
Specimen Label: 5 - Epas1
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:3506258
Assay Type: RNA in situ
Annotation Date: 2021-03-30
Strength: Present
Sex: Female
Emaps: EMAPS:2876523
Pattern: Widespread
Stage: TS23
Assay Id: MGI:6513163
Age: embryonic day 15.5
Image: 5 - Epas1
Specimen Label: 5 - Epas1
Detected: true
Specimen Num: 1
Publication
First Author: Gruber M
Year: 2010
Journal: Biol Reprod
Title: EPAS1 Is Required for Spermatogenesis in the Postnatal Mouse Testis.
Volume: 82
Issue: 6
Pages: 1227-36
GXD Expression
Probe: MGI:6172033
Assay Type: RNA in situ
Annotation Date: 2020-09-23
Strength: Present
Sex: Male
Emaps: EMAPS:1754426
Pattern: Regionally restricted
Stage: TS26
Assay Id: MGI:6456806
Age: embryonic day 18.5
Image: S13
Note: Epas1 is an endothelial marker.
Specimen Label: S13
Detected: true
Specimen Num: 1
Publication
First Author: Bernstein IR
Year: 2023
Journal: iScience
Title: The hypoxia-inducible factor EPAS1 is required for spermatogonial stem cell function in regenerative conditions.
Volume: 26
Issue: 12
Pages: 108424
Publication
First Author: Favier J
Year: 1999
Journal: FEBS Lett
Title: Cloning and expression pattern of EPAS1 in the chicken embryo. Colocalization with tyrosine hydroxylase.
Volume: 462
Issue: 1-2
Pages: 19-24
Publication  
First Author: Yamamura K
Year: 2017
Journal: Nat Commun
Title: The transcription factor EPAS1 links DOCK8 deficiency to atopic skin inflammation via IL-31 induction.
Volume: 8
Pages: 13946
Publication
First Author: Tian H
Year: 1998
Journal: Genes Dev
Title: The hypoxia-responsive transcription factor EPAS1 is essential for catecholamine homeostasis and protection against heart failure during embryonic development.
Volume: 12
Issue: 21
Pages: 3320-4
Publication
First Author: Liu N
Year: 2022
Journal: Cell Rep
Title: A highland-adaptation mutation of the Epas1 protein increases its stability and disrupts the circadian clock in the plateau pika.
Volume: 39
Issue: 7
Pages: 110816
GXD Expression    
Probe: MGI:6172033
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689419
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:6190209
Age: embryonic day 11.5
Specimen Label: Table S2 - E11.5 - Epas1
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:6172033
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689421
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:6190209
Age: embryonic day 13.5
Specimen Label: Table S2 - E13.5 - Epas1
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:6172033
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689424
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:6190209
Age: embryonic day 15.5
Specimen Label: Table S2 - E15.5 - Epas1
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:6172033
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689426
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:6190209
Age: embryonic day 18.5
Specimen Label: Table S2 - E18.5 - Epas1
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:6172033
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6190209
Age: postnatal day 4
Specimen Label: Table S2 - P4 - Epas1
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:6172033
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6190209
Age: postnatal day 14
Specimen Label: Table S2 - P14 - Epas1
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:6172033
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6190209
Age: postnatal day 28
Specimen Label: Table S2 - P28 - Epas1
Detected: true
Specimen Num: 7
Publication
First Author: Luque Y
Year: 2017
Journal: J Am Soc Nephrol
Title: Endothelial Epas1 Deficiency Is Sufficient To Promote Parietal Epithelial Cell Activation and FSGS in Experimental Hypertension.
Volume: 28
Issue: 12
Pages: 3563-3578
Publication
First Author: Yang S
Year: 2010
Journal: Nat Med
Title: Hypoxia-inducible factor-2alpha is a catabolic regulator of osteoarthritic cartilage destruction.
Volume: 16
Issue: 6
Pages: 687-93
Publication
First Author: Covello KL
Year: 2006
Journal: Genes Dev
Title: HIF-2alpha regulates Oct-4: effects of hypoxia on stem cell function, embryonic development, and tumor growth.
Volume: 20
Issue: 5
Pages: 557-70
Publication
First Author: Tian H
Year: 1997
Journal: Genes Dev
Title: Endothelial PAS domain protein 1 (EPAS1), a transcription factor selectively expressed in endothelial cells.
Volume: 11
Issue: 1
Pages: 72-82
Publication
First Author: Scortegagna M
Year: 2005
Journal: Blood
Title: HIF-2alpha regulates murine hematopoietic development in an erythropoietin-dependent manner.
Volume: 105
Issue: 8
Pages: 3133-40
Publication  
First Author: Nakazawa MS
Year: 2016
Journal: Nat Commun
Title: Epigenetic re-expression of HIF-2α suppresses soft tissue sarcoma growth.
Volume: 7
Pages: 10539
Publication
First Author: Kamikaseda Y
Year: 2021
Journal: J Allergy Clin Immunol
Title: Targeted inhibition of EPAS1-driven IL-31 production by a small-molecule compound.
Volume: 148
Issue: 2
Pages: 633-638
Publication
First Author: Ryu JH
Year: 2012
Journal: Cell Death Differ
Title: Hypoxia-inducible factor-2α regulates Fas-mediated chondrocyte apoptosis during osteoarthritic cartilage destruction.
Volume: 19
Issue: 3
Pages: 440-50
Publication
First Author: Oktay Y
Year: 2007
Journal: J Biol Chem
Title: Hypoxia-inducible factor 2alpha regulates expression of the mitochondrial aconitase chaperone protein frataxin.
Volume: 282
Issue: 16
Pages: 11750-6
Publication
First Author: Bridges JP
Year: 2012
Journal: Dev Biol
Title: Conditional hypoxia inducible factor-1α induction in embryonic pulmonary epithelium impairs maturation and augments lymphangiogenesis.
Volume: 362
Issue: 1
Pages: 24-41
Publication  
First Author: Moreno-Domínguez A
Year: 2020
Journal: Sci Signal
Title: Acute O2 sensing through HIF2α-dependent expression of atypical cytochrome oxidase subunits in arterial chemoreceptors.
Volume: 13
Issue: 615
Publication
First Author: Mangiavini L
Year: 2015
Journal: Am J Pathol
Title: Fibrosis and hypoxia-inducible factor-1α-dependent tumors of the soft tissue on loss of von Hippel-Lindau in mesenchymal progenitors.
Volume: 185
Issue: 11
Pages: 3090-101
Publication
First Author: Liyanage SE
Year: 2016
Journal: Arterioscler Thromb Vasc Biol
Title: Myeloid-Derived Vascular Endothelial Growth Factor and Hypoxia-Inducible Factor Are Dispensable for Ocular Neovascularization--Brief Report.
Volume: 36
Issue: 1
Pages: 19-24
Publication
First Author: Xue X
Year: 2013
Journal: Gastroenterology
Title: Endothelial PAS domain protein 1 activates the inflammatory response in the intestinal epithelium to promote colitis in mice.
Volume: 145
Issue: 4
Pages: 831-41
Publication  
First Author: Arroyo N
Year: 2021
Journal: JCI Insight
Title: GATA4 induces liver fibrosis regression by deactivating hepatic stellate cells.
Volume: 6
Issue: 23
Publication
First Author: Saito T
Year: 2010
Journal: Nat Med
Title: Transcriptional regulation of endochondral ossification by HIF-2alpha during skeletal growth and osteoarthritis development.
Volume: 16
Issue: 6
Pages: 678-86
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Luo X
Year: 2014
Journal: Biochim Biophys Acta
Title: Modulation of Dcytb (Cybrd 1) expression and function by iron, dehydroascorbate and Hif-2α in cultured cells.
Volume: 1840
Issue: 1
Pages: 106-12
Publication
First Author: Huang Y
Year: 2012
Journal: Am J Respir Cell Mol Biol
Title: Hypoxia-inducible factor 2α plays a critical role in the formation of alveoli and surfactant.
Volume: 46
Issue: 2
Pages: 224-32
Publication
First Author: Proper SP
Year: 2014
Journal: Toxicol Sci
Title: Loss of hypoxia-inducible factor 2 alpha in the lung alveolar epithelium of mice leads to enhanced eosinophilic inflammation in cobalt-induced lung injury.
Volume: 137
Issue: 2
Pages: 447-57
Publication
First Author: Moon JS
Year: 2022
Journal: Diabetes
Title: HIF-2α Preserves Mitochondrial Activity and Glucose Sensing in Compensating β-Cells in Obesity.
Volume: 71
Issue: 7
Pages: 1508-1524
Publication
First Author: Solanki S
Year: 2019
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Temporal induction of intestinal epithelial hypoxia-inducible factor-2α is sufficient to drive colitis.
Volume: 317
Issue: 2
Pages: G98-G107
Publication
First Author: Korovina I
Year: 2019
Journal: FASEB J
Title: Hematopoietic hypoxia-inducible factor 2α deficiency ameliorates pathological retinal neovascularization via modulation of endothelial cell apoptosis.
Volume: 33
Issue: 2
Pages: 1758-1770
Publication
First Author: Flores-Martínez A
Year: 2018
Journal: Sci Rep
Title: Stabilization of HIF-2α impacts pancreas growth.
Volume: 8
Issue: 1
Pages: 13713
Publication
First Author: Tan Q
Year: 2013
Journal: J Biol Chem
Title: Erythrocytosis and pulmonary hypertension in a mouse model of human HIF2A gain of function mutation.
Volume: 288
Issue: 24
Pages: 17134-44
Publication
First Author: Ghosh MC
Year: 2013
Journal: Cell Metab
Title: Deletion of iron regulatory protein 1 causes polycythemia and pulmonary hypertension in mice through translational derepression of HIF2α.
Volume: 17
Issue: 2
Pages: 271-81
Publication
First Author: Wang Z
Year: 2019
Journal: J Biol Chem
Title: Age-dependent decline of hypothalamic HIF2α in response to insulin and its contribution to advanced age-associated metabolic disorders in mice.
Volume: 294
Issue: 13
Pages: 4946-4955
Publication
First Author: Matak P
Year: 2013
Journal: PLoS One
Title: Copper deficiency leads to anemia, duodenal hypoxia, upregulation of HIF-2α and altered expression of iron absorption genes in mice.
Volume: 8
Issue: 3
Pages: e59538
Publication
First Author: Kleszka K
Year: 2020
Journal: Sci Rep
Title: Hypoxia-inducible factor-2α is crucial for proper brain development.
Volume: 10
Issue: 1
Pages: 19146
Publication
First Author: Gong H
Year: 2015
Journal: J Clin Invest
Title: HIF2α signaling inhibits adherens junctional disruption in acute lung injury.
Volume: 125
Issue: 2
Pages: 652-64
Publication
First Author: Duan LJ
Year: 2005
Journal: Circulation
Title: Endothelium-intrinsic requirement for Hif-2alpha during vascular development.
Volume: 111
Issue: 17
Pages: 2227-32
Publication
First Author: Scortegagna M
Year: 2003
Journal: Nat Genet
Title: Multiple organ pathology, metabolic abnormalities and impaired homeostasis of reactive oxygen species in Epas1-/- mice.
Volume: 35
Issue: 4
Pages: 331-40
Publication
First Author: Dioum EM
Year: 2008
Journal: Invest Ophthalmol Vis Sci
Title: HIF-2alpha-haploinsufficient mice have blunted retinal neovascularization due to impaired expression of a proangiogenic gene battery.
Volume: 49
Issue: 6
Pages: 2714-20
Publication
First Author: Ding K
Year: 2005
Journal: Invest Ophthalmol Vis Sci
Title: Retinal disease in mice lacking hypoxia-inducible transcription factor-2alpha.
Volume: 46
Issue: 3
Pages: 1010-6
Publication
First Author: Scortegagna M
Year: 2003
Journal: Blood
Title: The HIF family member EPAS1/HIF-2alpha is required for normal hematopoiesis in mice.
Volume: 102
Issue: 5
Pages: 1634-40
Publication
First Author: Ryu JH
Year: 2014
Journal: PLoS Biol
Title: Hypoxia-inducible factor-2α is an essential catabolic regulator of inflammatory rheumatoid arthritis.
Volume: 12
Issue: 6
Pages: e1001881
Publication
First Author: Brusselmans K
Year: 2003
Journal: J Clin Invest
Title: Heterozygous deficiency of hypoxia-inducible factor-2alpha protects mice against pulmonary hypertension and right ventricular dysfunction during prolonged hypoxia.
Volume: 111
Issue: 10
Pages: 1519-27
Publication
First Author: Hill P
Year: 2008
Journal: J Am Soc Nephrol
Title: Inhibition of hypoxia inducible factor hydroxylases protects against renal ischemia-reperfusion injury.
Volume: 19
Issue: 1
Pages: 39-46
Publication
First Author: Feng Z
Year: 2018
Journal: Proc Natl Acad Sci U S A
Title: Modulation of HIF-2α PAS-B domain contributes to physiological responses.
Volume: 115
Issue: 52
Pages: 13240-13245
Publication
First Author: Chan XY
Year: 2021
Journal: iScience
Title: HIF2A gain-of-function mutation modulates the stiffness of smooth muscle cells and compromises vascular mechanics.
Volume: 24
Issue: 4
Pages: 102246
Publication
First Author: Xu M
Year: 2014
Journal: Nat Med
Title: An acetate switch regulates stress erythropoiesis.
Volume: 20
Issue: 9
Pages: 1018-26
Publication
First Author: Forristal CE
Year: 2015
Journal: Leukemia
Title: Hypoxia inducible factor (HIF)-2α accelerates disease progression in mouse models of leukemia and lymphoma but is not a poor prognosis factor in human AML.
Volume: 29
Issue: 10
Pages: 2075-85
Publication
First Author: Fu L
Year: 2013
Journal: Cancer Res
Title: Activation of HIF2α in kidney proximal tubule cells causes abnormal glycogen deposition but not tumorigenesis.
Volume: 73
Issue: 9
Pages: 2916-25
Publication
First Author: Hanna C
Year: 2013
Journal: Am J Physiol Renal Physiol
Title: Hypoxia-inducible factor-2α and TGF-β signaling interact to promote normoxic glomerular fibrogenesis.
Volume: 305
Issue: 9
Pages: F1323-31
Publication
First Author: Tausendschön M
Year: 2015
Journal: Biochim Biophys Acta
Title: Genome-wide identification of hypoxia-inducible factor-1 and -2 binding sites in hypoxic human macrophages alternatively activated by IL-10.
Volume: 1849
Issue: 1
Pages: 10-22
Publication
First Author: Qi Y
Year: 2015
Journal: Cell Death Differ
Title: PTEN induces apoptosis and cavitation via HIF-2-dependent Bnip3 upregulation during epithelial lumen formation.
Volume: 22
Issue: 5
Pages: 875-84
Publication
First Author: Liu N
Year: 2019
Journal: J Clin Invest
Title: Lactate inhibits ATP6V0d2 expression in tumor-associated macrophages to promote HIF-2α-mediated tumor progression.
Volume: 129
Issue: 2
Pages: 631-646
Publication
First Author: Zhang X
Year: 2019
Journal: Cell Metab
Title: Adipocyte Hypoxia-Inducible Factor 2α Suppresses Atherosclerosis by Promoting Adipose Ceramide Catabolism.
Volume: 30
Issue: 5
Pages: 937-951.e5
Publication  
First Author: Riopel M
Year: 2020
Journal: Mol Metab
Title: Inhibition of prolyl hydroxylases increases hepatic insulin and decreases glucagon sensitivity by an HIF-2α-dependent mechanism.
Volume: 41
Pages: 101039
Publication  
First Author: Jain C
Year: 2023
Journal: Exp Hematol
Title: Myeloid Hif2α is not essential to maintain systemic iron homeostasis.
Volume: 125-126
Pages: 25-36.e1
GXD Expression      
Probe: MGI:3709865
Assay Type: RT-PCR
Annotation Date: 2007-05-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:3709997
Age: postnatal month 3
Specimen Label: +/+
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:3709865
Assay Type: RT-PCR
Annotation Date: 2007-05-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:3709997
Age: postnatal month 3
Specimen Label: +/-
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:3709865
Assay Type: RT-PCR
Annotation Date: 2007-05-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:3709997
Age: postnatal month 3
Specimen Label: -/-
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:3709865
Assay Type: RT-PCR
Annotation Date: 2007-05-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610520
Stage: TS20
Assay Id: MGI:3709998
Age: embryonic day 12.5
Specimen Label: +/+
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:3709865
Assay Type: RT-PCR
Annotation Date: 2007-05-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610520
Stage: TS20
Assay Id: MGI:3709998
Age: embryonic day 12.5
Specimen Label: +/-
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:3709865
Assay Type: RT-PCR
Annotation Date: 2007-05-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610520
Stage: TS20
Assay Id: MGI:3709998
Age: embryonic day 12.5
Specimen Label: -/-
Detected: true
Specimen Num: 3