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Search results 1 to 100 out of 321 for Ephx2

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Type Details Score
Gene
2053 | EPHX2
Type: gene
Organism: human
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Gene
477373 | EPHX2
Type: gene
Organism: dog, domestic
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Gene
511716 | EPHX2
Type: gene
Organism: cattle
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Gene
421999 | EPHX2
Type: gene
Organism: chicken
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Gene
494099 | ephx2
Type: gene
Organism: zebrafish
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Gene
712926 | EPHX2
Type: gene
Organism: macaque, rhesus
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Gene
448759 | ephx2
Type: gene
Organism: frog, western clawed
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Gene
65030 | Ephx2
Type: gene
Organism: rat
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Gene
464074 | EPHX2
Type: gene
Organism: chimpanzee
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Protein Coding Gene
MGI:99500 | Ephx2
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
17135253 | J:120290
First Author: Luria A
Year: 2007
Journal: J Biol Chem
Title: Compensatory mechanism for homeostatic blood pressure regulation in Ephx2 gene-disrupted mice.
Volume: 282
Issue: 5
Pages: 2891-8
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Publication
26722453 | J:333596
First Author: Zhong L
Year: 2015
Journal: Int J Clin Exp Pathol
Title: Proteomics and bioinformatics analysis of mouse hypothalamic neurogenesis with or without EPHX2 gene deletion.
Volume: 8
Issue: 10
Pages: 12634-45
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Publication
36822325 | J:334942
First Author: Edin ML
Year: 2023
Journal: J Biol Chem
Title: Disruption of Ephx2 in cardiomyocytes but not endothelial cells improves functional recovery after ischemia-reperfusion in isolated mouse hearts.
Volume: 299
Issue: 4
Pages: 103049
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Publication
28056085 | J:245920
First Author: Hanif A
Year: 2017
Journal: PLoS One
Title: Vascular Endothelial Over-Expression of Human Soluble Epoxide Hydrolase (Tie2-sEH Tr) Attenuates Coronary Reactive Hyperemia in Mice: Role of Oxylipins and ω-Hydroxylases.
Volume: 12
Issue: 1
Pages: e0169584
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Publication
23585883 | J:200585
First Author: Zhang W
Year: 2013
Journal: PLoS One
Title: Role of endothelial soluble epoxide hydrolase in cerebrovascular function and ischemic injury.
Volume: 8
Issue: 4
Pages: e61244
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Publication
27629787 | J:302882
First Author: Yadav VR
Year: 2016
Journal: Mol Cell Biochem
Title: Vascular endothelial over-expression of soluble epoxide hydrolase (Tie2-sEH) enhances adenosine A1 receptor-dependent contraction in mouse mesenteric arteries: role of ATP-sensitive K+ channels.
Volume: 422
Issue: 1-2
Pages: 197-206
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Publication
21059750 | J:277964
First Author: Deng Y
Year: 2011
Journal: FASEB J
Title: Endothelial CYP epoxygenase overexpression and soluble epoxide hydrolase disruption attenuate acute vascular inflammatory responses in mice.
Volume: 25
Issue: 2
Pages: 703-13
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Publication
24458713 | J:302773
First Author: Shao Z
Year: 2014
Journal: Arterioscler Thromb Vasc Biol
Title: Cytochrome P450 2C8 ω3-long-chain polyunsaturated fatty acid metabolites increase mouse retinal pathologic neovascularization--brief report.
Volume: 34
Issue: 3
Pages: 581-6
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Publication
28827330 | J:244902
First Author: Hasegawa E
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: Cytochrome P450 monooxygenase lipid metabolites are significant second messengers in the resolution of choroidal neovascularization.
Volume: 114
Issue: 36
Pages: E7545-E7553
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Publication
27401401 | J:327207
 
First Author: Wells MA
Year: 2016
Journal: Prostaglandins Other Lipid Mediat
Title: Characterization of the Cytochrome P450 epoxyeicosanoid pathway in non-alcoholic steatohepatitis.
Volume: 125
Pages: 19-29
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Publication
28028752 | J:272774
First Author: Li Y
Year: 2017
Journal: Inflammation
Title: Cigarette Smoke-Induced Pulmonary Inflammation and Autophagy Are Attenuated in Ephx2-Deficient Mice.
Volume: 40
Issue: 2
Pages: 497-510
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Publication
23898174 | J:200694
First Author: Panigrahy D
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Epoxyeicosanoids promote organ and tissue regeneration.
Volume: 110
Issue: 33
Pages: 13528-33
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Publication
19458064 | J:151245
First Author: Luria A
Year: 2009
Journal: Am J Physiol Endocrinol Metab
Title: Alteration in plasma testosterone levels in male mice lacking soluble epoxide hydrolase.
Volume: 297
Issue: 2
Pages: E375-83
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Publication
25310404 | J:223563
First Author: Schuck RN
Year: 2014
Journal: PLoS One
Title: The cytochrome P450 epoxygenase pathway regulates the hepatic inflammatory response in fatty liver disease.
Volume: 9
Issue: 10
Pages: e110162
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Publication
22414856 | J:302892
First Author: Liu Y
Year: 2012
Journal: J Pharmacol Exp Ther
Title: Attenuation of cisplatin-induced renal injury by inhibition of soluble epoxide hydrolase involves nuclear factor κB signaling.
Volume: 341
Issue: 3
Pages: 725-34
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Publication
29206762 | J:302893
First Author: Tao W
Year: 2018
Journal: Shock
Title: Soluble Epoxide Hydrolase Plays a Vital Role in Angiotensin II-Induced Lung Injury in Mice.
Volume: 50
Issue: 5
Pages: 589-594
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Publication
20439437 | J:302888
First Author: Luo P
Year: 2010
Journal: J Pharmacol Exp Ther
Title: Inhibition or deletion of soluble epoxide hydrolase prevents hyperglycemia, promotes insulin secretion, and reduces islet apoptosis.
Volume: 334
Issue: 2
Pages: 430-8
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Publication
25402489 | J:225303
First Author: Bettaieb A
Year: 2014
Journal: PLoS One
Title: Effects of soluble epoxide hydrolase deficiency on acute pancreatitis in mice.
Volume: 9
Issue: 11
Pages: e113019
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Publication
24718617 | J:333595
First Author: Li L
Year: 2014
Journal: PLoS One
Title: Opposite effects of gene deficiency and pharmacological inhibition of soluble epoxide hydrolase on cardiac fibrosis.
Volume: 9
Issue: 4
Pages: e94092
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Publication
29615440 | J:262223
First Author: Sun H
Year: 2018
Journal: Diabetes
Title: Inhibition of Soluble Epoxide Hydrolase 2 Ameliorates Diabetic Keratopathy and Impaired Wound Healing in Mouse Corneas.
Volume: 67
Issue: 6
Pages: 1162-1172
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Publication
20035028 | J:158430
First Author: Simpkins AN
Year: 2010
Journal: Am J Physiol Heart Circ Physiol
Title: Soluble epoxide hydrolase inhibition modulates vascular remodeling.
Volume: 298
Issue: 3
Pages: H795-806
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Publication
33378686 | J:327167
 
First Author: Wang L
Year: 2021
Journal: J Mol Cell Cardiol
Title: Soluble epoxide hydrolase deficiency attenuates lipotoxic cardiomyopathy via upregulation of AMPK-mTORC mediated autophagy.
Volume: 154
Pages: 80-91
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Publication
19285984 | J:157145
First Author: Katragadda D
Year: 2009
Journal: J Mol Cell Cardiol
Title: Epoxyeicosatrienoic acids limit damage to mitochondrial function following stress in cardiac cells.
Volume: 46
Issue: 6
Pages: 867-75
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Publication
16857962 | J:124860
First Author: Seubert JM
Year: 2006
Journal: Circ Res
Title: Role of soluble epoxide hydrolase in postischemic recovery of heart contractile function.
Volume: 99
Issue: 4
Pages: 442-50
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Publication
34142887 | J:322262
First Author: Hu S
Year: 2021
Journal: Am J Physiol Heart Circ Physiol
Title: Soluble epoxide hydrolase deletion attenuated nicotine-induced arterial stiffness via limiting the loss of SIRT1.
Volume: 321
Issue: 2
Pages: H353-H368
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Publication
30890645 | J:274391
First Author: Ma M
Year: 2019
Journal: Proc Natl Acad Sci U S A
Title: Key role of soluble epoxide hydrolase in the neurodevelopmental disorders of offspring after maternal immune activation.
Volume: 116
Issue: 14
Pages: 7083-7088
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Publication
31801085 | J:301056
First Author: Qin XH
Year: 2019
Journal: Cell Rep
Title: Liver Soluble Epoxide Hydrolase Regulates Behavioral and Cellular Effects of Chronic Stress.
Volume: 29
Issue: 10
Pages: 3223-3234.e6
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Publication
24448199 | J:302768
First Author: Zhang H
Year: 2014
Journal: Crit Care Med
Title: Deletion of soluble epoxide hydrolase attenuates cardiac hypertrophy via down-regulation of cardiac fibroblasts-derived fibroblast growth factor-2.
Volume: 42
Issue: 5
Pages: e345-54
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Publication
22641086 | J:192422
 
First Author: Fairbanks SL
Year: 2012
Journal: Neuroscience
Title: Mechanism of the sex difference in neuronal ischemic cell death.
Volume: 219
Pages: 183-91
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Publication
22922090 | J:302881
 
First Author: Strauss KI
Year: 2013
Journal: Prostaglandins Other Lipid Mediat
Title: Altered behavioral phenotypes in soluble epoxide hydrolase knockout mice: effects of traumatic brain injury.
Volume: 104-105
Pages: 18-24
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Publication
21832210 | J:178808
First Author: Elmarakby AA
Year: 2011
Journal: Am J Physiol Regul Integr Comp Physiol
Title: Deletion of soluble epoxide hydrolase gene improves renal endothelial function and reduces renal inflammation and injury in streptozotocin-induced type 1 diabetes.
Volume: 301
Issue: 5
Pages: R1307-17
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Publication
29298899 | J:262336
First Author: Edin ML
Year: 2018
Journal: J Biol Chem
Title: Epoxide hydrolase 1 (EPHX1) hydrolyzes epoxyeicosanoids and impairs cardiac recovery after ischemia.
Volume: 293
Issue: 9
Pages: 3281-3292
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Publication
30902874 | J:276521
First Author: Xiong W
Year: 2019
Journal: J Neurosci
Title: Astrocytic Epoxyeicosatrienoic Acid Signaling in the Medial Prefrontal Cortex Modulates Depressive-like Behaviors.
Volume: 39
Issue: 23
Pages: 4606-4623
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Publication
32973044 | J:296602
First Author: Chen W
Year: 2020
Journal: J Neurosci
Title: 14,15-Epoxyeicosatrienoic Acid Alleviates Pathology in a Mouse Model of Alzheimer's Disease.
Volume: 40
Issue: 42
Pages: 8188-8203
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Publication
20008276 | J:158438
First Author: Merkel MJ
Year: 2010
Journal: Am J Physiol Heart Circ Physiol
Title: Inhibition of soluble epoxide hydrolase preserves cardiomyocytes: role of STAT3 signaling.
Volume: 298
Issue: 2
Pages: H679-87
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Publication
34591792 | J:327212
 
First Author: Li H
Year: 2021
Journal: J Clin Invest
Title: sEH promotes macrophage phagocytosis and lung clearance of Streptococcus pneumoniae.
Volume: 131
Issue: 22
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Protein Coding Gene
MGP_CAROLIEiJ_G0019435 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0021491 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0021450 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0021426 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0021456 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0021233 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_99500 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0021895 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0020750 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0021200 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0021323 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0021302 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0021398 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0021331 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0021918 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0020494 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0020803 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0030453 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0020327 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
8349642 | J:14045
First Author: Grant DF
Year: 1993
Journal: J Biol Chem
Title: Molecular cloning and expression of murine liver soluble epoxide hydrolase.
Volume: 268
Issue: 23
Pages: 17628-33
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Publication
21217101 | J:170657
First Author: Cronin A
Year: 2011
Journal: J Lipid Res
Title: Mammalian soluble epoxide hydrolase is identical to liver hepoxilin hydrolase.
Volume: 52
Issue: 4
Pages: 712-9
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Publication
17900570 | J:126926
First Author: Shkolnik K
Year: 2007
Journal: FEBS Lett
Title: A novel ovary-specific and ovulation-associated variant of epoxide hydrolase 2.
Volume: 581
Issue: 25
Pages: 4891-8
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Publication
22665795 | J:185508
First Author: Frömel T
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Soluble epoxide hydrolase regulates hematopoietic progenitor cell function via generation of fatty acid diols.
Volume: 109
Issue: 25
Pages: 9995-10000
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Publication
28485854 | J:274977
First Author: Bettaieb A
Year: 2017
Journal: FEBS J
Title: Podocyte-specific soluble epoxide hydrolase deficiency in mice attenuates acute kidney injury.
Volume: 284
Issue: 13
Pages: 1970-1986
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Publication
28757338 | J:255617
First Author: Bettaieb A
Year: 2017
Journal: Biochim Biophys Acta
Title: Soluble epoxide hydrolase in podocytes is a significant contributor to renal function under hyperglycemia.
Volume: 1861
Issue: 11 Pt A
Pages: 2758-2765
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Publication
24843165 | J:211353
First Author: Charles RL
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Protection from hypertension in mice by the Mediterranean diet is mediated by nitro fatty acid inhibition of soluble epoxide hydrolase.
Volume: 111
Issue: 22
Pages: 8167-72
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Publication
32006628 | J:289384
 
First Author: Wack G
Year: 2020
Journal: Neurosci Lett
Title: Redox regulation of soluble epoxide hydrolase does not affect pain behavior in mice.
Volume: 721
Pages: 134798
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Publication
36594097 | J:341695
First Author: Zhang J
Year: 2023
Journal: Int J Biol Sci
Title: Direct targeting of sEH with alisol B alleviated the apoptosis, inflammation, and oxidative stress in cisplatin-induced acute kidney injury.
Volume: 19
Issue: 1
Pages: 294-310
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Publication
31479425 | J:284090
First Author: Hu J
Year: 2019
Journal: J Clin Invest
Title: Soluble epoxide hydrolase promotes astrocyte survival in retinopathy of prematurity.
Volume: 129
Issue: 12
Pages: 5204-5218
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Publication
36899838 | J:334980
 
First Author: Li X
Year: 2023
Journal: Cells
Title: 11,12-EET Regulates PPAR-γ Expression to Modulate TGF-β-Mediated Macrophage Polarization.
Volume: 12
Issue: 5
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Publication
34281173 | J:321186
 
First Author: Kesavan R
Year: 2021
Journal: Int J Mol Sci
Title: The Consequences of Soluble Epoxide Hydrolase Deletion on Tumorigenesis and Metastasis in a Mouse Model of Breast Cancer.
Volume: 22
Issue: 13
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Publication
11001943 | J:71007
First Author: Sinal CJ
Year: 2000
Journal: J Biol Chem
Title: Targeted disruption of soluble epoxide hydrolase reveals a role in blood pressure regulation.
Volume: 275
Issue: 51
Pages: 40504-10
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Publication
19679679 | J:172557
First Author: Keserü B
Year: 2010
Journal: Cardiovasc Res
Title: Hypoxia-induced pulmonary hypertension: comparison of soluble epoxide hydrolase deletion vs. inhibition.
Volume: 85
Issue: 1
Pages: 232-40
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Publication
29311641 | J:260142
First Author: Chang LH
Year: 2018
Journal: Sci Rep
Title: Blockade of soluble epoxide hydrolase attenuates post-ischemic neuronal hyperexcitation and confers resilience against stroke with TrkB activation.
Volume: 8
Issue: 1
Pages: 118
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Publication
24324059 | J:302765
First Author: Zhang W
Year: 2013
Journal: Anticancer Res
Title: Soluble epoxide hydrolase deficiency inhibits dextran sulfate sodium-induced colitis and carcinogenesis in mice.
Volume: 33
Issue: 12
Pages: 5261-5271
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Publication
24924124 | J:302766
First Author: Wagner K
Year: 2014
Journal: J Pain
Title: Soluble epoxide hydrolase inhibition is antinociceptive in a mouse model of diabetic neuropathy.
Volume: 15
Issue: 9
Pages: 907-14
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Publication
23576437 | J:199627
First Author: Bettaieb A
Year: 2013
Journal: J Biol Chem
Title: Soluble epoxide hydrolase deficiency or inhibition attenuates diet-induced endoplasmic reticulum stress in liver and adipose tissue.
Volume: 288
Issue: 20
Pages: 14189-99
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Publication
18835921 | J:141436
First Author: Motoki A
Year: 2008
Journal: Am J Physiol Heart Circ Physiol
Title: Soluble epoxide hydrolase inhibition and gene deletion are protective against myocardial ischemia-reperfusion injury in vivo.
Volume: 295
Issue: 5
Pages: H2128-34
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Publication
22922020 | J:302880
 
First Author: Chaudhary KR
Year: 2013
Journal: Prostaglandins Other Lipid Mediat
Title: Differential effects of soluble epoxide hydrolase inhibition and CYP2J2 overexpression on postischemic cardiac function in aged mice.
Volume: 104-105
Pages: 8-17
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Publication
31847859 | J:302810
First Author: Lee HT
Year: 2019
Journal: J Neuroinflammation
Title: Genetic deletion of soluble epoxide hydrolase delays the progression of Alzheimer's disease.
Volume: 16
Issue: 1
Pages: 267
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Publication
32116760 | J:290699
 
First Author: Jamieson KL
Year: 2020
Journal: Front Physiol
Title: Age and Sex Differences in Hearts of Soluble Epoxide Hydrolase Null Mice.
Volume: 11
Pages: 48
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Publication
18927469 | J:159789
First Author: Hercule HC
Year: 2009
Journal: Arterioscler Thromb Vasc Biol
Title: Interaction between P450 eicosanoids and nitric oxide in the control of arterial tone in mice.
Volume: 29
Issue: 1
Pages: 54-60
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Publication
31436906 | J:296959
First Author: Lien CC
Year: 2019
Journal: J Cell Mol Med
Title: The phosphatase activity of soluble epoxide hydrolase regulates ATP-binding cassette transporter-A1-dependent cholesterol efflux.
Volume: 23
Issue: 10
Pages: 6611-6621
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Publication
28450284 | J:243441
First Author: Kandhi S
Year: 2017
Journal: Am J Physiol Lung Cell Mol Physiol
Title: EETs promote hypoxic pulmonary vasoconstriction via constrictor prostanoids.
Volume: 313
Issue: 2
Pages: L350-L359
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Publication
21571638 | J:173238
First Author: Luria A
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Soluble epoxide hydrolase deficiency alters pancreatic islet size and improves glucose homeostasis in a model of insulin resistance.
Volume: 108
Issue: 22
Pages: 9038-43
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Publication
30692927 | J:327205
 
First Author: Samokhvalov V
Year: 2018
Journal: Front Pharmacol
Title: Deficiency of Soluble Epoxide Hydrolase Protects Cardiac Function Impaired by LPS-Induced Acute Inflammation.
Volume: 9
Pages: 1572
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Publication
31319469 | J:294419
 
First Author: Darwesh AM
Year: 2019
Journal: Int J Mol Sci
Title: Genetic Deletion or Pharmacological Inhibition of Soluble Epoxide Hydrolase Ameliorates Cardiac Ischemia/Reperfusion Injury by Attenuating NLRP3 Inflammasome Activation.
Volume: 20
Issue: 14
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Publication
22720061 | J:187826
First Author: Liu Y
Year: 2012
Journal: PLoS One
Title: Inhibition of soluble epoxide hydrolase attenuates high-fat-diet-induced hepatic steatosis by reduced systemic inflammatory status in mice.
Volume: 7
Issue: 6
Pages: e39165
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Publication
23000418 | J:327210
 
First Author: Oni-Orisan A
Year: 2013
Journal: Prostaglandins Other Lipid Mediat
Title: Dual modulation of cyclooxygenase and CYP epoxygenase metabolism and acute vascular inflammation in mice.
Volume: 104-105
Pages: 67-73
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Publication
27815261 | J:237509
First Author: Wepler M
Year: 2016
Journal: Am J Physiol Lung Cell Mol Physiol
Title: Soluble epoxide hydrolase deficiency or inhibition enhances murine hypoxic pulmonary vasoconstriction after lipopolysaccharide challenge.
Volume: 311
Issue: 6
Pages: L1213-L1221
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Publication
28104457 | J:302885
 
First Author: Jamieson KL
Year: 2017
Journal: Prostaglandins Other Lipid Mediat
Title: Genetic deletion of soluble epoxide hydrolase provides cardioprotective responses following myocardial infarction in aged mice.
Volume: 132
Pages: 47-58
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19471280 | J:302890
First Author: Zhang W
Year: 2009
Journal: J Cereb Blood Flow Metab
Title: Role of soluble epoxide hydrolase in the sex-specific vascular response to cerebral ischemia.
Volume: 29
Issue: 8
Pages: 1475-81
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26840748 | J:302891
 
First Author: Carratt SA
Year: 2016
Journal: Toxicol Lett
Title: Naphthalene cytotoxicity in microsomal epoxide hydrolase deficient mice.
Volume: 246
Pages: 35-41
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25128026 | J:302886
First Author: Qin X
Year: 2015
Journal: Mol Neurobiol
Title: Soluble Epoxide Hydrolase Deficiency or Inhibition Attenuates MPTP-Induced Parkinsonism.
Volume: 52
Issue: 1
Pages: 187-95
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