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Search results 1 to 100 out of 120 for Erbin

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Hits by Strain

Type Details Score
Protein Domain
IPR032927 | Erbin
Type: Family
Description: Erbin (also known as Protein LAP2), was first identified as an adaptor for the receptor ERBB2/HER2 in epithelia []. It is involved in inhibition of several intracellular signalling pathways, such as Ras-mediated activation of extracellular signal-regulated kinase (ERK), nuclear factor kappaB, and transforming growth factor beta signalling pathways [].It contains an N-terminal domain with 16 leucine-rich repeats and a C-terminal PDZ domain. Through its amino-terminal region, Erbin disrupts Ras-Raf interaction by preventing the Ras-binding protein Shoc2 from binding to Ras, and thus acting as a tumour suppressor [].
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Gene
55914 | ERBIN
Type: gene
Organism: human
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Gene
734027 | erbin
Type: gene
Organism: frog, western clawed
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Protein
Q80TH2
Organism: Mus musculus/domesticus
Length: 1402  
Fragment?: false
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Protein
B2RUJ2
Organism: Mus musculus/domesticus
Length: 1294  
Fragment?: false
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Protein
B7ZNX6
Organism: Mus musculus/domesticus
Length: 1411  
Fragment?: false
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Gene
471527 | ERBIN
Type: gene
Organism: chimpanzee
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Gene
365661 | Erbin
Type: gene
Organism: rat
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Gene
512866 | ERBIN
Type: gene
Organism: cattle
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Gene
100856182 | ERBIN
Type: gene
Organism: dog, domestic
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Gene
431583 | ERBIN
Type: gene
Organism: chicken
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Gene
566811 | erbin
Type: gene
Organism: zebrafish
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Gene
700429 | ERBIN
Type: gene
Organism: macaque, rhesus
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Protein Coding Gene
MGI:1890169 | Erbin
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
24711380 | J:208862
First Author: Rachmin I
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Erbin is a negative modulator of cardiac hypertrophy.
Volume: 111
Issue: 16
Pages: 5902-7
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Publication
10878805 | J:63225
First Author: Borg JP
Year: 2000
Journal: Nat Cell Biol
Title: ERBIN: a basolateral PDZ protein that interacts with the mammalian ERBB2/HER2 receptor.
Volume: 2
Issue: 7
Pages: 407-14
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Publication
26056141 | J:227321
First Author: Xie CM
Year: 2015
Journal: J Cell Biol
Title: Erbin is a novel substrate of the Sag-βTrCP E3 ligase that regulates KrasG12D-induced skin tumorigenesis.
Volume: 209
Issue: 5
Pages: 721-37
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Protein
Q80TH2-2
Organism: Mus musculus/domesticus
Length: 1450  
Fragment?: false
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Protein
Q80TH2-1
Organism: Mus musculus/domesticus
Length: 1376  
Fragment?: false
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Gene
118732300 | ERBIN-DT
Type: gene
Organism: human
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Publication
16203728 | J:221560
First Author: McDonald C
Year: 2005
Journal: J Biol Chem
Title: A role for Erbin in the regulation of Nod2-dependent NF-kappaB signaling.
Volume: 280
Issue: 48
Pages: 40301-9
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Publication
19458253 | J:149996
First Author: Tao Y
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: Erbin regulates NRG1 signaling and myelination.
Volume: 106
Issue: 23
Pages: 9477-82
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Publication
23100438 | J:192171
First Author: Liang C
Year: 2012
Journal: J Neurosci
Title: Erbin is required for myelination in regenerated axons after injury.
Volume: 32
Issue: 43
Pages: 15169-80
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Publication
18614673 | J:138014
First Author: Arikkath J
Year: 2008
Journal: J Neurosci
Title: Erbin controls dendritic morphogenesis by regulating localization of delta-catenin.
Volume: 28
Issue: 28
Pages: 7047-56
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Publication
25288731 | J:216431
First Author: Tao Y
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Role of Erbin in ErbB2-dependent breast tumor growth.
Volume: 111
Issue: 42
Pages: E4429-38
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Publication
29980571 | J:265562
First Author: Stevens PD
Year: 2018
Journal: Cancer Res
Title: Erbin Suppresses KSR1-Mediated RAS/RAF Signaling and Tumorigenesis in Colorectal Cancer.
Volume: 78
Issue: 17
Pages: 4839-4852
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Protein
B7ZNY4
Organism: Mus musculus/domesticus
Length: 1402  
Fragment?: false
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Protein
B2RUK2
Organism: Mus musculus/domesticus
Length: 1450  
Fragment?: false
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Publication
23354328 | J:197472
First Author: Tao Y
Year: 2013
Journal: Nat Neurosci
Title: Erbin interacts with TARP γ-2 for surface expression of AMPA receptors in cortical interneurons.
Volume: 16
Issue: 3
Pages: 290-9
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Publication
29552291 | J:279110
First Author: Shen T
Year: 2018
Journal: Oncotarget
Title: Erbin exerts a protective effect against inflammatory bowel disease by suppressing autophagic cell death.
Volume: 9
Issue: 15
Pages: 12035-12049
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Publication
11279080 | J:81503
First Author: Huang YZ
Year: 2001
Journal: J Biol Chem
Title: Erbin is a protein concentrated at postsynaptic membranes that interacts with PSD-95.
Volume: 276
Issue: 22
Pages: 19318-26
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UniProt Feature
UniProt Feature
Begin: 1
Description: Erbin
Type: chain
End: 1402
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Publication
20463225 | J:160528
First Author: Simeone L
Year: 2010
Journal: J Neurosci
Title: Identification of Erbin interlinking MuSK and ErbB2 and its impact on acetylcholine receptor aggregation at the neuromuscular junction.
Volume: 30
Issue: 19
Pages: 6620-34
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Publication
25521828 | J:220610
First Author: Yao S
Year: 2015
Journal: J Pathol
Title: Erbin interacts with c-Cbl and promotes tumourigenesis and tumour growth in colorectal cancer by preventing c-Cbl-mediated ubiquitination and down-regulation of EGFR.
Volume: 236
Issue: 1
Pages: 65-77
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Publication
38232736 | J:346091
First Author: Zhang Z
Year: 2024
Journal: Cell Metab
Title: Targeting Erbin-mitochondria axis in platelets/megakaryocytes promotes B cell-mediated antitumor immunity.
Volume: 36
Issue: 3
Pages: 541-556.e9
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Publication
27321929 | J:237217
First Author: Kravic B
Year: 2016
Journal: J Neurochem
Title: LAP proteins are localized at the post-synaptic membrane of neuromuscular junctions and appear to modulate synaptic morphology and transmission.
Volume: 139
Issue: 3
Pages: 381-395
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Publication
12650946 | J:230356
First Author: Warner DR
Year: 2003
Journal: FEBS Lett
Title: Identification of three novel Smad binding proteins involved in cell polarity.
Volume: 539
Issue: 1-3
Pages: 167-73
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Protein Coding Gene
MGP_CAROLIEiJ_G0018856 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0020901 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0020852 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0020827 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0020852 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0020641 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_1890169 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0021286 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0020160 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0020603 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0020727 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0020709 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0020801 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0020737 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0021325 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0019913 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0020218 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0015928 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0019735 | -
Type: protein_coding_gene
Organism: Mus spretus
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GXD Expression
GXD Expression
   
Probe: MGI:947088
Assay Type: RNA in situ
Annotation Date: 2018-12-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3270422
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:6267440
Age: embryonic day 14.5
Specimen Label: Table S1
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:947088
Assay Type: RNA in situ
Annotation Date: 2024-04-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3270422
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7621150
Age: embryonic day 14.5
Specimen Label: Supplementary table 2
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:947088
Assay Type: RNA in situ
Annotation Date: 2018-12-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3271222
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:6267440
Age: embryonic day 14.5
Specimen Label: Table S1
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:3584805
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1915528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:3586109
Age: postnatal day 6-7
Image: P6/7
Specimen Label: P6/7
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
     
Probe: MGI:3584805
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1647028
Stage: TS28
Assay Id: MGI:3586109
Age: postnatal day 6
Specimen Label: CNS
Detected: false
Specimen Num: 5
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GXD Expression
GXD Expression
Probe: MGI:3584805
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1915727
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:3586109
Age: postnatal day 2-3
Image: P2/3
Note: Expression was detected in the outer neuroblastic layer.
Specimen Label: P2/3
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:3584805
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1915728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:3586109
Age: postnatal day 4-5
Image: P4/5
Note: Expression was detected in the outer neuroblastic layer.
Specimen Label: P4/5
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:3584805
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1915728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:3586109
Age: postnatal day 6-7
Image: P6/7
Specimen Label: P6/7
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
 
Probe: MGI:3584805
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Present
Sex: Male
Emaps: EMAPS:1915728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:3586109
Age: postnatal adult
Image: Adult
Specimen Label: Adult
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:947088
Assay Type: RNA in situ
Annotation Date: 2018-12-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3270322
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:6267440
Age: embryonic day 14.5
Specimen Label: Table S1
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:947088
Assay Type: RNA in situ
Annotation Date: 2018-12-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754722
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:6267440
Age: embryonic day 14.5
Specimen Label: Table S1
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:947088
Assay Type: RNA in situ
Annotation Date: 2024-04-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754722
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7621150
Age: embryonic day 14.5
Specimen Label: Supplementary table 2
Detected: true
Specimen Num: 1
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Publication
12693553 | J:83413
First Author: Okazaki N
Year: 2003
Journal: DNA Res
Title: Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.
Volume: 10
Issue: 1
Pages: 35-48
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Publication
24997765 | J:214959
First Author: Lodato S
Year: 2014
Journal: Nat Neurosci
Title: Gene co-regulation by Fezf2 selects neurotransmitter identity and connectivity of corticospinal neurons.
Volume: 17
Issue: 8
Pages: 1046-54
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Publication
16107646 | J:100324
First Author: Bulfone A
Year: 2005
Journal: J Neurosci
Title: Telencephalic embryonic subtractive sequences: a unique collection of neurodevelopmental genes.
Volume: 25
Issue: 33
Pages: 7586-600
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Publication
21862448 | J:198109
First Author: Oeschger FM
Year: 2012
Journal: Cereb Cortex
Title: Gene expression analysis of the embryonic subplate.
Volume: 22
Issue: 6
Pages: 1343-59
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
10512203 | J:93290
First Author: Araki K
Year: 1999
Journal: Cell Mol Biol (Noisy-le-grand)
Title: Exchangeable gene trap using the Cre/mutated lox system.
Volume: 45
Issue: 5
Pages: 737-50
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Publication
15840001 | J:110088
First Author: Taniwaki T
Year: 2005
Journal: Dev Growth Differ
Title: Characterization of an exchangeable gene trap using pU-17 carrying a stop codon-beta geo cassette.
Volume: 47
Issue: 3
Pages: 163-72
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Publication
15226823 | J:93300
First Author: Blackshaw S
Year: 2004
Journal: PLoS Biol
Title: Genomic analysis of mouse retinal development.
Volume: 2
Issue: 9
Pages: E247
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Publication
- | J:68100
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: RIKEN Data Curation in Mouse Genome Informatics
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Publication
- | J:84900
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Journal: Database Download
Title: Integrating Computational Gene Models into the Mouse Genome Informatics (MGI) Database
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Publication
12520002 | J:91812
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
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Publication
34321999 | J:313619
 
First Author: Bedogni F
Year: 2021
Journal: Front Mol Neurosci
Title: Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development.
Volume: 14
Pages: 686034
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Publication
- | J:155856
       
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
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Publication
- | J:342604
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
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Publication
- | J:78475
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

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