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Search results 1 to 100 out of 255 for Ercc1

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Type Details Score
Gene
2067 | ERCC1
Type: gene
Organism: human
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Gene
615637 | ERCC1
Type: gene
Organism: cattle
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Gene
100001425 | ercc1
Type: gene
Organism: zebrafish
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Gene
574267 | ERCC1
Type: gene
Organism: macaque, rhesus
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Gene
100135224 | ercc1
Type: gene
Organism: frog, western clawed
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Gene
292673 | Ercc1
Type: gene
Organism: rat
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Gene
612282 | ERCC1
Type: gene
Organism: dog, domestic
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Gene
450179 | ERCC1
Type: gene
Organism: chimpanzee
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HT Sample
ercc1
Organism Name: mouse, laboratory
Sex: Not Specified
Age: postnatal day 15
Stage: 28
Structure . Name: white fat
Notes: epididymal fat pad
Curation Status: Curated
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Protein Coding Gene
MGI:95412 | Ercc1
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
12713813 | J:341303
First Author: Winter AG
Year: 2003
Journal: DNA Repair (Amst)
Title: The repair and recombination enzyme ERCC1 is not required for immunoglobulin class switching.
Volume: 2
Issue: 5
Pages: 561-9
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Publication
11713303 | J:106084
First Author: Selfridge J
Year: 2001
Journal: Nucleic Acids Res
Title: Correction of liver dysfunction in DNA repair-deficient mice with an ERCC1 transgene.
Volume: 29
Issue: 22
Pages: 4541-50
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Publication
17126084 | J:127200
First Author: Kirschner K
Year: 2007
Journal: DNA Repair (Amst)
Title: Characterisation of Ercc1 deficiency in the liver and in conditional Ercc1-deficient primary hepatocytes in vitro.
Volume: 6
Issue: 3
Pages: 304-16
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Publication
18221731 | J:341304
First Author: Lawrence NJ
Year: 2008
Journal: DNA Repair (Amst)
Title: A neurological phenotype in mice with DNA repair gene Ercc1 deficiency.
Volume: 7
Issue: 2
Pages: 281-91
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Publication
27514406 | J:236871
First Author: Jokić M
Year: 2016
Journal: Mol Cancer Res
Title: Ercc1 Deficiency Promotes Tumorigenesis and Increases Cisplatin Sensitivity in a Tp53 Context-Specific Manner.
Volume: 14
Issue: 11
Pages: 1110-1123
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Publication
20602234 | J:333265
First Author: de Waard MC
Year: 2010
Journal: Acta Neuropathol
Title: Age-related motor neuron degeneration in DNA repair-deficient Ercc1 mice.
Volume: 120
Issue: 4
Pages: 461-75
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Publication
20407824 | J:333284
First Author: Song L
Year: 2011
Journal: Transgenic Res
Title: A novel transcript for DNA repair gene Ercc1 in mouse skin.
Volume: 20
Issue: 1
Pages: 109-22
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Publication
20362516 | J:162032
First Author: Selfridge J
Year: 2010
Journal: DNA Repair (Amst)
Title: Mice with DNA repair gene Ercc1 deficiency in a neural crest lineage are a model for late-onset Hirschsprung disease.
Volume: 9
Issue: 6
Pages: 653-60
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Publication
12466203 | J:80586
First Author: Hsia KT
Year: 2003
Journal: Development
Title: DNA repair gene Ercc1 is essential for normal spermatogenesis and oogenesis and for functional integrity of germ cell DNA in the mouse.
Volume: 130
Issue: 2
Pages: 369-78
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Publication
22701168 | J:206925
 
First Author: Verhagen-Oldenampsen JH
Year: 2012
Journal: Anemia
Title: Loss of ercc1 results in a time- and dose-dependent reduction of proliferating early hematopoietic progenitors.
Volume: 2012
Pages: 783068
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Publication
34830315 | J:333269
 
First Author: van Thiel BS
Year: 2021
Journal: Int J Mol Sci
Title: In Vivo Renin Activity Imaging in the Kidney of Progeroid Ercc1 Mutant Mice.
Volume: 22
Issue: 22
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Publication
31737985 | J:311389
First Author: Kim DE
Year: 2020
Journal: Aging Cell
Title: Deficiency in the DNA repair protein ERCC1 triggers a link between senescence and apoptosis in human fibroblasts and mouse skin.
Volume: 19
Issue: 3
Pages: e13072
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Publication
15280420 | J:92471
First Author: Schrader CE
Year: 2004
Journal: J Exp Med
Title: Deletion of the nucleotide excision repair gene Ercc1 reduces immunoglobulin class switching and alters mutations near switch recombination junctions.
Volume: 200
Issue: 3
Pages: 321-30
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Publication
9197240 | J:41161
First Author: Weeda G
Year: 1997
Journal: Curr Biol
Title: Disruption of mouse ERCC1 results in a novel repair syndrome with growth failure, nuclear abnormalities and senescence.
Volume: 7
Issue: 6
Pages: 427-39
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Publication
26384430 | J:233786
First Author: Liu YC
Year: 2015
Journal: Nucleic Acids Res
Title: CITED2 silencing sensitizes cancer cells to cisplatin by inhibiting p53 trans-activation and chromatin relaxation on the ERCC1 DNA repair gene.
Volume: 43
Issue: 22
Pages: 10760-81
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HT Experiment
E-MEXP-3930 | Transcription profiling by array of mouse Ercc1 knock out white adipose tissue
 
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
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Publication
34504640 | J:325223
 
First Author: Ataei Ataabadi E
Year: 2021
Journal: Oxid Med Cell Longev
Title: Vascular Ageing Features Caused by Selective DNA Damage in Smooth Muscle Cell.
Volume: 2021
Pages: 2308317
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Publication
23399551 | J:333264
First Author: de Graaf EL
Year: 2013
Journal: Mol Cell Proteomics
Title: Spatio-temporal analysis of molecular determinants of neuronal degeneration in the aging mouse cerebellum.
Volume: 12
Issue: 5
Pages: 1350-62
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Publication
19264557 | J:309206
First Author: Lawrence NJ
Year: 2009
Journal: DNA Repair (Amst)
Title: Topical thymidine dinucleotide application protects against UVB-induced skin cancer in mice with DNA repair gene (Ercc1)-deficient skin.
Volume: 8
Issue: 5
Pages: 664-71
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Publication
17912366 | J:130019
First Author: Paul C
Year: 2007
Journal: PLoS One
Title: Deletion of genes implicated in protecting the integrity of male germ cells has differential effects on the incidence of DNA breaks and germ cell loss.
Volume: 2
Issue: 10
Pages: e989
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Publication
24799273 | J:213229
First Author: Raj DD
Year: 2014
Journal: Neurobiol Aging
Title: Priming of microglia in a DNA-repair deficient model of accelerated aging.
Volume: 35
Issue: 9
Pages: 2147-60
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Publication
16682947 | J:115849
First Author: Doig J
Year: 2006
Journal: Oncogene
Title: Mice with skin-specific DNA repair gene (Ercc1) inactivation are hypersensitive to ultraviolet irradiation-induced skin cancer and show more rapid actinic progression.
Volume: 25
Issue: 47
Pages: 6229-38
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Publication
33068332 | J:303683
First Author: Zhang X
Year: 2021
Journal: Glia
Title: Intrinsic DNA damage repair deficiency results in progressive microglia loss and replacement.
Volume: 69
Issue: 3
Pages: 729-745
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Publication
36760711 | J:333116
 
First Author: Birkisdóttir MB
Year: 2022
Journal: Front Aging Neurosci
Title: Purkinje-cell-specific DNA repair-deficient mice reveal that dietary restriction protects neurons by cell-intrinsic preservation of genomic health.
Volume: 14
Pages: 1095801
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Publication
21880916 | J:176221
First Author: Borgesius NZ
Year: 2011
Journal: J Neurosci
Title: Accelerated age-related cognitive decline and neurodegeneration, caused by deficient DNA repair.
Volume: 31
Issue: 35
Pages: 12543-53
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Publication
2558854 | J:10222
First Author: Mohrenweiser HW
Year: 1989
Journal: Cytogenet Cell Genet
Title: Refined mapping of the three DNA repair genes, ERCC1, ERCC2, and XRCC1, on human chromosome 19.
Volume: 52
Issue: 1-2
Pages: 11-4
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Publication
22953029 | J:202585
   
First Author: Dollé ME
Year: 2011
Journal: Pathobiol Aging Age Relat Dis
Title: Broad segmental progeroid changes in short-lived Ercc1(-/Δ7) mice.
Volume: 1
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Publication
27210754 | J:235960
First Author: Sepe S
Year: 2016
Journal: Cell Rep
Title: Inefficient DNA Repair Is an Aging-Related Modifier of Parkinson's Disease.
Volume: 15
Issue: 9
Pages: 1866-75
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Publication
34020718 | J:333148
First Author: Van't Sant LJ
Year: 2021
Journal: Acta Neuropathol Commun
Title: In vivo 5-ethynyluridine (EU) labelling detects reduced transcription in Purkinje cell degeneration mouse mutants, but can itself induce neurodegeneration.
Volume: 9
Issue: 1
Pages: 94
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Publication
37220109 | J:346279
First Author: Rogers RS
Year: 2023
Journal: PLoS Biol
Title: Hypoxia extends lifespan and neurological function in a mouse model of aging.
Volume: 21
Issue: 5
Pages: e3002117
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Publication
33493548 | J:313319
 
First Author: Huerta Guevara AP
Year: 2021
Journal: Metabolism
Title: Increased insulin sensitivity and diminished pancreatic beta-cell function in DNA repair deficient Ercc1d/- mice.
Volume: 117
Pages: 154711
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Publication
22245387 | J:264341
First Author: Smith SC
Year: 2012
Journal: Neurobiol Dis
Title: Downregulation of cholesterol biosynthesis genes in the forebrain of ERCC1-deficient mice.
Volume: 45
Issue: 3
Pages: 1136-44
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Publication
11707424 | J:72856
First Author: Niedernhofer LJ
Year: 2001
Journal: EMBO J
Title: The structure-specific endonuclease Ercc1-Xpf is required for targeted gene replacement in embryonic stem cells.
Volume: 20
Issue: 22
Pages: 6540-9
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Publication
10214917 | J:54389
First Author: de Boer J
Year: 1999
Journal: Biochimie
Title: Cancer from the outside, aging from the inside: mouse models to study the consequences of defective nucleotide excision repair.
Volume: 81
Issue: 1-2
Pages: 127-37
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Publication
30306644 | J:268300
First Author: Borggrewe M
Year: 2018
Journal: Glia
Title: VISTA expression by microglia decreases during inflammation and is differentially regulated in CNS diseases.
Volume: 66
Issue: 12
Pages: 2645-2658
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Publication
22705887 | J:202206
First Author: Durik M
Year: 2012
Journal: Circulation
Title: Nucleotide excision DNA repair is associated with age-related vascular dysfunction.
Volume: 126
Issue: 4
Pages: 468-78
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Publication
15692571 | J:96496
First Author: Prasher JM
Year: 2005
Journal: EMBO J
Title: Reduced hematopoietic reserves in DNA interstrand crosslink repair-deficient Ercc1-/- mice.
Volume: 24
Issue: 4
Pages: 861-71
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Publication
23648546 | J:202380
First Author: Mitra D
Year: 2013
Journal: J Invest Dermatol
Title: Smad4 loss in mouse keratinocytes leads to increased susceptibility to UV carcinogenesis with reduced Ercc1-mediated DNA repair.
Volume: 133
Issue: 11
Pages: 2609-2616
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Publication
15199134 | J:91596
First Author: Niedernhofer LJ
Year: 2004
Journal: Mol Cell Biol
Title: The structure-specific endonuclease Ercc1-Xpf is required to resolve DNA interstrand cross-link-induced double-strand breaks.
Volume: 24
Issue: 13
Pages: 5776-87
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Publication
28871086 | J:252245
First Author: Fuhrmann-Stroissnigg H
Year: 2017
Journal: Nat Commun
Title: Identification of HSP90 inhibitors as a novel class of senolytics.
Volume: 8
Issue: 1
Pages: 422
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Publication
18541667 | J:335431
First Author: Ahmad A
Year: 2008
Journal: Mol Cell Biol
Title: ERCC1-XPF endonuclease facilitates DNA double-strand break repair.
Volume: 28
Issue: 16
Pages: 5082-92
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Publication
10834928 | J:62553
First Author: Núñez F
Year: 2000
Journal: FASEB J
Title: Nucleotide excision repair gene (ERCC1) deficiency causes G(2) arrest in hepatocytes and a reduction in liver binucleation: the role of p53 and p21.
Volume: 14
Issue: 9
Pages: 1073-82
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Publication
23281008 | J:233255
First Author: Chen Q
Year: 2013
Journal: J Bone Miner Res
Title: DNA damage drives accelerated bone aging via an NF-κB-dependent mechanism.
Volume: 28
Issue: 5
Pages: 1214-28
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Publication
27556946 | J:236604
First Author: Vermeij WP
Year: 2016
Journal: Nature
Title: Restricted diet delays accelerated ageing and genomic stress in DNA-repair-deficient mice.
Volume: 537
Issue: 7620
Pages: 427-431
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Publication
28368372 | J:246103
First Author: Chatzinikolaou G
Year: 2017
Journal: Nat Cell Biol
Title: ERCC1-XPF cooperates with CTCF and cohesin to facilitate the developmental silencing of imprinted genes.
Volume: 19
Issue: 5
Pages: 421-432
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Publication
25538220 | J:218236
First Author: Perez-Oliva AB
Year: 2015
Journal: EMBO J
Title: USP45 deubiquitylase controls ERCC1-XPF endonuclease-mediated DNA damage responses.
Volume: 34
Issue: 3
Pages: 326-43
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Publication
15979950 | J:105008
First Author: Griffin C
Year: 2005
Journal: DNA Repair (Amst)
Title: The involvement of key DNA repair pathways in the formation of chromosome rearrangements in embryonic stem cells.
Volume: 4
Issue: 9
Pages: 1019-27
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Protein Coding Gene
MGP_CAROLIEiJ_G0029284 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0031771 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0031747 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0031673 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0031752 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0031474 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_95412 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0032218 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0030817 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0031436 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0031591 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0031543 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0031674 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0031579 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0032246 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0030541 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0030917 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0021144 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0030368 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
3290851 | J:9239
First Author: van Duin M
Year: 1988
Journal: Nucleic Acids Res
Title: Evolution and mutagenesis of the mammalian excision repair gene ERCC-1.
Volume: 16
Issue: 12
Pages: 5305-22
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Publication
8275084 | J:15422
First Author: McWhir J
Year: 1993
Journal: Nat Genet
Title: Mice with DNA repair gene (ERCC-1) deficiency have elevated levels of p53, liver nuclear abnormalities and die before weaning.
Volume: 5
Issue: 3
Pages: 217-24
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Publication
- | J:18601
First Author: McWhir J
Year: 1994
Journal: Genet Res
Title: Mice with DNA repair gene (ERCC-1) deficiency have elevated levels of p53, liver nuclear abnormalities and die before weaning
Volume: 63
Issue: 2
Pages: 157 (Abstr.)
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Publication
31896748 | J:289930
First Author: Goulielmaki E
Year: 2020
Journal: Nat Commun
Title: Tissue-infiltrating macrophages mediate an exosome-based metabolic reprogramming upon DNA damage.
Volume: 11
Issue: 1
Pages: 42
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Publication
24011075 | J:203815
First Author: Karakasilioti I
Year: 2013
Journal: Cell Metab
Title: DNA damage triggers a chronic autoinflammatory response, leading to fat depletion in NER progeria.
Volume: 18
Issue: 3
Pages: 403-15
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Publication
25754370 | J:223785
First Author: Zhu Y
Year: 2015
Journal: Aging Cell
Title: The Achilles' heel of senescent cells: from transcriptome to senolytic drugs.
Volume: 14
Issue: 4
Pages: 644-58
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Publication
23947592 | J:202486
 
First Author: Schermer B
Year: 2013
Journal: BMC Genomics
Title: Transcriptional profiling reveals progeroid Ercc1(-/Δ) mice as a model system for glomerular aging.
Volume: 14
Pages: 559
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Publication
22257940 | J:280844
First Author: Spoor M
Year: 2012
Journal: Mech Ageing Dev
Title: Accelerated loss of hearing and vision in the DNA-repair deficient Ercc1(δ/-) mouse.
Volume: 133
Issue: 2-3
Pages: 59-67
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Publication
30916493 | J:283378
First Author: Alyodawi K
Year: 2019
Journal: J Cachexia Sarcopenia Muscle
Title: Compression of morbidity in a progeroid mouse model through the attenuation of myostatin/activin signalling.
Volume: 10
Issue: 3
Pages: 662-686
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Publication
27418353 | J:243245
First Author: van Beek AA
Year: 2017
Journal: J Leukoc Biol
Title: Frontline Science: Tryptophan restriction arrests B cell development and enhances microbial diversity in WT and prematurely aging Ercc1-/Δ7 mice.
Volume: 101
Issue: 4
Pages: 811-821
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Publication
20798040 | J:164379
First Author: Hagelstrom RT
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Hyper telomere recombination accelerates replicative senescence and may promote premature aging.
Volume: 107
Issue: 36
Pages: 15768-73
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Publication
23097336 | J:194705
First Author: Cho JS
Year: 2013
Journal: Stem Cells
Title: Cell autonomous and nonautonomous mechanisms drive hematopoietic stem/progenitor cell loss in the absence of DNA repair.
Volume: 31
Issue: 3
Pages: 511-25
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Publication
29860127 | J:333270
 
First Author: Czerwińska J
Year: 2018
Journal: Free Radic Biol Med
Title: ERCC1-deficient cells and mice are hypersensitive to lipid peroxidation.
Volume: 124
Pages: 79-96
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Publication
23927039 | J:214882
First Author: Roh DS
Year: 2013
Journal: Aging Cell
Title: Age-related dystrophic changes in corneal endothelium from DNA repair-deficient mice.
Volume: 12
Issue: 6
Pages: 1122-31
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Publication
21596054 | J:335409
First Author: Goss JR
Year: 2011
Journal: Mech Ageing Dev
Title: Premature aging-related peripheral neuropathy in a mouse model of progeria.
Volume: 132
Issue: 8-9
Pages: 437-42
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Publication
17183314 | J:117488
First Author: Niedernhofer LJ
Year: 2006
Journal: Nature
Title: A new progeroid syndrome reveals that genotoxic stress suppresses the somatotroph axis.
Volume: 444
Issue: 7122
Pages: 1038-43
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Publication
10454634 | J:56965
First Author: Van Sloun PP
Year: 1999
Journal: Nucleic Acids Res
Title: The role of nucleotide excision repair in protecting embryonic stem cells from genotoxic effects of UV-induced DNA damage.
Volume: 27
Issue: 16
Pages: 3276-82
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Publication
3919454 | J:44382
First Author: Thompson LH
Year: 1985
Journal: Somat Cell Mol Genet
Title: Correction of a nucleotide-excision-repair mutation by human chromosome 19 in hamster-human hybrid cells.
Volume: 11
Issue: 1
Pages: 87-92
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Publication
1730160 | J:2722
First Author: Chao CC
Year: 1992
Journal: Clin Immunol Immunopathol
Title: Effects of swimming exercise on the pathogenesis of acute murine Toxoplasma gondii Me49 infection.
Volume: 62
Issue: 2
Pages: 220-6
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Publication
8287470 | J:44490
First Author: Cleaver JE
Year: 1994
Journal: Cell
Title: It was a very good year for DNA repair.
Volume: 76
Issue: 1
Pages: 1-4
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Publication
19805513 | J:154992
First Author: Bhagwat N
Year: 2009
Journal: Mol Cell Biol
Title: XPF-ERCC1 participates in the Fanconi anemia pathway of cross-link repair.
Volume: 29
Issue: 24
Pages: 6427-37
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GXD Expression
GXD Expression
     
Probe: MGI:7580520
Assay Type: Northern blot
Annotation Date: 2024-02-07
Strength: Present
Sex: Male
Emaps: EMAPS:3598828
Stage: TS28
Assay Id: MGI:7580530
Age: postnatal adult
Specimen Label: Muscle
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:7580520
Assay Type: Northern blot
Annotation Date: 2024-02-07
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:7580530
Age: postnatal adult
Specimen Label: Testis
Detected: true
Specimen Num: 2
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•
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•
GXD Expression
GXD Expression
     
Probe: MGI:7580520
Assay Type: Northern blot
Annotation Date: 2024-02-07
Strength: Present
Sex: Male
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:7580530
Age: postnatal adult
Specimen Label: Kidney
Detected: true
Specimen Num: 3
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