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Search results 1 to 100 out of 144 for Ercc2

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Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: zebrafish
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: hamster, Chinese
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: chimpanzee
HT Sample
Organism Name: mouse, laboratory
Sex: Not Specified
Age: postnatal day 15
Stage: 28
Structure . Name: white fat
Notes: epididymal fat pad
Curation Status: Curated
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Publication
First Author: Lamerdin JE
Year: 1996
Journal: Genomics
Title: Sequence analysis of the ERCC2 gene regions in human, mouse, and hamster reveals three linked genes.
Volume: 34
Issue: 3
Pages: 399-409
Publication
First Author: Mohrenweiser HW
Year: 1989
Journal: Cytogenet Cell Genet
Title: Refined mapping of the three DNA repair genes, ERCC1, ERCC2, and XRCC1, on human chromosome 19.
Volume: 52
Issue: 1-2
Pages: 11-4
Publication
First Author: Nicolaije C
Year: 2012
Journal: PLoS One
Title: Age-related skeletal dynamics and decrease in bone strength in DNA repair deficient male trichothiodystrophy mice.
Volume: 7
Issue: 4
Pages: e35246
Publication
First Author: Weber CA
Year: 1988
Journal: Mol Cell Biol
Title: Molecular cloning and biological characterization of a human gene, ERCC2, that corrects the nucleotide excision repair defect in CHO UV5 cells.
Volume: 8
Issue: 3
Pages: 1137-46
Publication
First Author: Levy HP
Year: 1992
Journal: Cytogenet Cell Genet
Title: Comparative gene mapping in the species Muntiacus muntjac.
Volume: 61
Issue: 4
Pages: 276-81
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Andressoo JO
Year: 2006
Journal: PLoS Biol
Title: Rescue of progeria in trichothiodystrophy by homozygous lethal Xpd alleles.
Volume: 4
Issue: 10
Pages: e322
Publication
First Author: de Boer J
Year: 1998
Journal: Mol Cell
Title: A mouse model for the basal transcription/DNA repair syndrome trichothiodystrophy.
Volume: 1
Issue: 7
Pages: 981-90
Publication
First Author: Wijnhoven SW
Year: 2005
Journal: DNA Repair (Amst)
Title: Accelerated aging pathology in ad libitum fed Xpd(TTD) mice is accompanied by features suggestive of caloric restriction.
Volume: 4
Issue: 11
Pages: 1314-24
Publication
First Author: Baar MP
Year: 2017
Journal: Cell
Title: Targeted Apoptosis of Senescent Cells Restores Tissue Homeostasis in Response to Chemotoxicity and Aging.
Volume: 169
Issue: 1
Pages: 132-147.e16
Publication
First Author: Compe E
Year: 2005
Journal: Mol Cell Biol
Title: Dysregulation of the peroxisome proliferator-activated receptor target genes by XPD mutations.
Volume: 25
Issue: 14
Pages: 6065-76
Publication
First Author: Lehmann AR
Year: 2001
Journal: Genes Dev
Title: The xeroderma pigmentosum group D (XPD) gene: one gene, two functions, three diseases.
Volume: 15
Issue: 1
Pages: 15-23
Publication
First Author: Baden HP
Year: 1976
Journal: Am J Hum Genet
Title: The physicochemical properties of hair in the BIDS syndrome.
Volume: 28
Issue: 5
Pages: 514-21
Publication
First Author: van de Ven M
Year: 2012
Journal: DNA Repair (Amst)
Title: Effects of compound heterozygosity at the Xpd locus on cancer and ageing in mouse models.
Volume: 11
Issue: 11
Pages: 874-83
GXD Expression
Probe: MGI:5689405
Assay Type: Immunohistochemistry
Annotation Date: 2015-10-08
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1783825
Pattern: Non-Uniform
Stage: TS25
Assay Id: MGI:5689410
Age: embryonic day 17.5
Image: C3H E17.5
Note: Expression is present at the anterior and posterior parts of the primary lens fiber cells.
Specimen Label: C3H E17.5
Detected: true
Specimen Num: 1
GXD Expression
Probe: MGI:5689405
Assay Type: Immunohistochemistry
Annotation Date: 2015-10-08
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1783827
Pattern: Non-Uniform
Stage: TS27
Assay Id: MGI:5689410
Age: postnatal day 1
Image: C3H P1
Note: Expression is present at the anterior and posterior parts of the primary lens fiber cells.
Specimen Label: C3H P1
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:5689405
Assay Type: Immunohistochemistry
Annotation Date: 2015-10-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1783828
Pattern: Widespread
Stage: TS28
Assay Id: MGI:5689410
Age: postnatal day 7
Image: C3H P7
Specimen Label: C3H P7
Detected: true
Specimen Num: 3
GXD Expression
Probe: MGI:5689405
Assay Type: Immunohistochemistry
Annotation Date: 2015-10-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1783828
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:5689410
Age: postnatal day 14
Image: C3H P14
Note: Expression is present in a ring; it is not present in the lens nucleus or equatorial bow region.
Specimen Label: C3H P14
Detected: true
Specimen Num: 4
GXD Expression  
Probe: MGI:5689405
Assay Type: Immunohistochemistry
Annotation Date: 2015-10-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1783825
Pattern: Not Specified
Stage: TS25
Assay Id: MGI:5689410
Age: embryonic day 17.5
Image: het E17.5
Specimen Label: het E17.5
Detected: true
Specimen Num: 5
GXD Expression
Probe: MGI:5689405
Assay Type: Immunohistochemistry
Annotation Date: 2015-10-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1783828
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:5689410
Age: postnatal day 14
Image: het P14
Note: Expression is present in a ring; it is not present in the lens nucleus or equatorial bow region.
Specimen Label: het P14
Detected: true
Specimen Num: 8
GXD Expression  
Probe: MGI:5689405
Assay Type: Immunohistochemistry
Annotation Date: 2015-10-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1783825
Pattern: Not Specified
Stage: TS25
Assay Id: MGI:5689410
Age: embryonic day 17.5
Image: hom E17.5
Specimen Label: hom E17.5
Detected: true
Specimen Num: 9
GXD Expression  
Probe: MGI:5689405
Assay Type: Immunohistochemistry
Annotation Date: 2015-10-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1783827
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:5689410
Age: postnatal day 1
Image: hom P1
Specimen Label: hom P1
Detected: true
Specimen Num: 10
GXD Expression  
Probe: MGI:5689405
Assay Type: Immunohistochemistry
Annotation Date: 2015-10-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1783828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5689410
Age: postnatal day 7
Image: hom P7
Specimen Label: hom P7
Detected: true
Specimen Num: 11
GXD Expression
Probe: MGI:5689405
Assay Type: Immunohistochemistry
Annotation Date: 2015-10-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1783828
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:5689410
Age: postnatal day 14
Image: hom P14
Note: Expression is present in a ring; it is not present in the lens nucleus or equatorial bow region. This ring is smaller in mutants compared to wild type.
Specimen Label: hom P14
Detected: true
Specimen Num: 12
GXD Expression  
Probe: MGI:5689405
Assay Type: Immunohistochemistry
Annotation Date: 2015-10-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1783828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5689410
Age: postnatal day 7
Image: het P7
Specimen Label: het P7
Detected: true
Specimen Num: 7
GXD Expression  
Probe: MGI:5689405
Assay Type: Immunohistochemistry
Annotation Date: 2015-10-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1783827
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:5689410
Age: postnatal day 1
Image: het P1
Specimen Label: het P1
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:3584806
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1915528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:3586170
Age: postnatal day 6-7
Specimen Label: P6/7
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:3584806
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1915528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:3586170
Age: postnatal day 8-10
Specimen Label: P8/10
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:3584806
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Present
Sex: Male
Emaps: EMAPS:1915528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:3586170
Age: postnatal adult
Specimen Label: Adult
Detected: true
Specimen Num: 7
GXD Expression  
Probe: MGI:3584806
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1647028
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:3586170
Age: postnatal day 6
Note: Expression was widespread.
Specimen Label: CNS
Detected: true
Specimen Num: 8
GXD Expression  
Probe: MGI:3584806
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1915726
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:3586170
Age: embryonic day 18.0
Note: Expression was detected in the outer neuroblastic layer.
Specimen Label: E18
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:3584806
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1915727
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:3586170
Age: postnatal day 0-1
Note: Expression was detected in the outer neuroblastic layer.
Specimen Label: P0/1
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:3584806
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1915727
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:3586170
Age: postnatal day 2-3
Note: Expression was detected in the outer neuroblastic layer.
Specimen Label: P2/3
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:3584806
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1915728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:3586170
Age: postnatal day 4-5
Note: Expression was detected in the outer neuroblastic layer.
Specimen Label: P4/5
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:3584806
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1915728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:3586170
Age: postnatal day 6-7
Specimen Label: P6/7
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:3584806
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1915728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:3586170
Age: postnatal day 8-10
Specimen Label: P8/10
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:3584806
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Present
Sex: Male
Emaps: EMAPS:1915728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:3586170
Age: postnatal adult
Specimen Label: Adult
Detected: true
Specimen Num: 7
GXD Expression    
Probe: MGI:3584806
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684624
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:3586170
Age: embryonic day 16.0
Specimen Label: Embryo
Detected: true
Specimen Num: 9
GXD Expression    
Probe: MGI:3584806
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1877124
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:3586170
Age: embryonic day 16.0
Specimen Label: Embryo
Detected: true
Specimen Num: 9
Publication
First Author: de Boer J
Year: 1998
Journal: Cancer Res
Title: Disruption of the mouse xeroderma pigmentosum group D DNA repair/basal transcription gene results in preimplantation lethality.
Volume: 58
Issue: 1
Pages: 89-94
Publication
First Author: Kunze S
Year: 2015
Journal: PLoS One
Title: New mutation in the mouse Xpd/Ercc2 gene leads to recessive cataracts.
Volume: 10
Issue: 5
Pages: e0125304
Publication
First Author: Dalke C
Year: 2018
Journal: Radiat Environ Biophys
Title: Lifetime study in mice after acute low-dose ionizing radiation: a multifactorial study with special focus on cataract risk.
Volume: 57
Issue: 2
Pages: 99-113
Publication
First Author: Rossi DJ
Year: 2007
Journal: Nature
Title: Deficiencies in DNA damage repair limit the function of haematopoietic stem cells with age.
Volume: 447
Issue: 7145
Pages: 725-9
Publication
First Author: Matsumura H
Year: 2016
Journal: Science
Title: Hair follicle aging is driven by transepidermal elimination of stem cells via COL17A1 proteolysis.
Volume: 351
Issue: 6273
Pages: aad4395
Publication
First Author: Park JY
Year: 2008
Journal: PLoS One
Title: Homeostatic imbalance between apoptosis and cell renewal in the liver of premature aging Xpd mice.
Volume: 3
Issue: 6
Pages: e2346
Publication
First Author: de Boer J
Year: 2002
Journal: Science
Title: Premature aging in mice deficient in DNA repair and transcription.
Volume: 296
Issue: 5571
Pages: 1276-9
Publication
First Author: Durik M
Year: 2012
Journal: Circulation
Title: Nucleotide excision DNA repair is associated with age-related vascular dysfunction.
Volume: 126
Issue: 4
Pages: 468-78
Publication
First Author: Kaushik Tiwari M
Year: 2013
Journal: Nucleic Acids Res
Title: XPD-dependent activation of apoptosis in response to triplex-induced DNA damage.
Volume: 41
Issue: 19
Pages: 8979-94
Publication
First Author: Godon C
Year: 2012
Journal: EMBO J
Title: Generation of DNA single-strand displacement by compromised nucleotide excision repair.
Volume: 31
Issue: 17
Pages: 3550-63
Publication
First Author: Andressoo JO
Year: 2006
Journal: Cancer Cell
Title: An Xpd mouse model for the combined xeroderma pigmentosum/Cockayne syndrome exhibiting both cancer predisposition and segmental progeria.
Volume: 10
Issue: 2
Pages: 121-32
Publication
First Author: van de Ven M
Year: 2006
Journal: PLoS Genet
Title: Adaptive stress response in segmental progeria resembles long-lived dwarfism and calorie restriction in mice.
Volume: 2
Issue: 12
Pages: e192
Publication
First Author: Andressoo JO
Year: 2009
Journal: Mol Cell Biol
Title: An Xpb mouse model for combined xeroderma pigmentosum and cockayne syndrome reveals progeroid features upon further attenuation of DNA repair.
Volume: 29
Issue: 5
Pages: 1276-90
Publication
First Author: Le May N
Year: 2004
Journal: Cell
Title: TFIIH transcription factor, a target for the Rift Valley hemorrhagic fever virus.
Volume: 116
Issue: 4
Pages: 541-50
Publication
First Author: Garssen J
Year: 2000
Journal: J Immunol
Title: Transcription-coupled and global genome repair differentially influence UV-B-induced acute skin effects and systemic immunosuppression.
Volume: 164
Issue: 12
Pages: 6199-205
Publication
First Author: de Boer J
Year: 1999
Journal: Cancer Res
Title: Mouse model for the DNA repair/basal transcription disorder trichothiodystrophy reveals cancer predisposition.
Volume: 59
Issue: 14
Pages: 3489-94
Publication      
First Author: Klaften M
Year: 2006
Journal: PhD Thesis - HelmholtzZentrum München
Title: Ein neuartiges Konzept zur genomweiten Kartierung von ENU-induzierten Mausmutanten in Hochdurchsatz.
Publication
First Author: Dollé ME
Year: 2006
Journal: Mutat Res
Title: Increased genomic instability is not a prerequisite for shortened lifespan in DNA repair deficient mice.
Volume: 596
Issue: 1-2
Pages: 22-35
Publication
First Author: Traboulsi H
Year: 2014
Journal: PLoS Genet
Title: Dynamic partnership between TFIIH, PGC-1α and SIRT1 is impaired in trichothiodystrophy.
Volume: 10
Issue: 10
Pages: e1004732
Publication
First Author: Mirabella F
Year: 2010
Journal: J Immunol
Title: The human IL-3/granulocyte-macrophage colony-stimulating factor locus is epigenetically silent in immature thymocytes and is progressively activated during T cell development.
Volume: 184
Issue: 6
Pages: 3043-54
Publication
First Author: Jaarsma D
Year: 2011
Journal: PLoS Genet
Title: Age-related neuronal degeneration: complementary roles of nucleotide excision repair and transcription-coupled repair in preventing neuropathology.
Volume: 7
Issue: 12
Pages: e1002405
Publication
First Author: Nonnekens J
Year: 2013
Journal: Hum Mol Genet
Title: Mutations in TFIIH causing trichothiodystrophy are responsible for defects in ribosomal RNA production and processing.
Volume: 22
Issue: 14
Pages: 2881-93
Publication
First Author: Compe E
Year: 2007
Journal: Nat Neurosci
Title: Neurological defects in trichothiodystrophy reveal a coactivator function of TFIIH.
Volume: 10
Issue: 11
Pages: 1414-22
Publication
First Author: Jacobs H
Year: 1998
Journal: J Exp Med
Title: Hypermutation of immunoglobulin genes in memory B cells of DNA repair-deficient mice.
Volume: 187
Issue: 11
Pages: 1735-43
Publication
First Author: Rudert F
Year: 1992
Journal: Mamm Genome
Title: Characterization of murine carcinoembryonic antigen gene family members.
Volume: 3
Issue: 5
Pages: 262-73
Publication
First Author: Saunders AM
Year: 1990
Journal: Genomics
Title: The syntenic relationship of proximal mouse chromosome 7 and the myotonic dystrophy gene region on human chromosome 19q.
Volume: 6
Issue: 2
Pages: 324-32
Publication
First Author: Hrabé de Angelis MH
Year: 2000
Journal: Nat Genet
Title: Genome-wide, large-scale production of mutant mice by ENU mutagenesis.
Volume: 25
Issue: 4
Pages: 444-7
Publication
First Author: Sano M
Year: 2007
Journal: Cell Metab
Title: Ménage-à-trois 1 is critical for the transcriptional function of PPARgamma coactivator 1.
Volume: 5
Issue: 2
Pages: 129-42
Publication
First Author: Saunders AM
Year: 1990
Journal: Genomics
Title: A molecular genetic linkage map of mouse chromosome 7.
Volume: 8
Issue: 3
Pages: 525-35
Publication
First Author: Ko MS
Year: 1998
Journal: Hum Mol Genet
Title: Genome-wide mapping of unselected transcripts from extraembryonic tissue of 7.5-day mouse embryos reveals enrichment in the t-complex and under-representation on the X chromosome.
Volume: 7
Issue: 12
Pages: 1967-78
Publication      
First Author: European Mouse Mutant Archive
Year: 2003
Journal: Unpublished
Title: Information obtained from the European Mouse Mutant Archive (EMMA)