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Search results 1 to 91 out of 91 for Erlin2

0.018s

Categories

Hits by Pathway

Hits by Category

Hits by Strain

Type Details Score
Gene
11160 | ERLIN2
Type: gene
Organism: human
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Gene
549473 | erlin2
Type: gene
Organism: frog, western clawed
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Gene
290823 | Erlin2
Type: gene
Organism: rat
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Gene
607518 | ERLIN2
Type: gene
Organism: dog, domestic
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Gene
464112 | ERLIN2
Type: gene
Organism: chimpanzee
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Gene
616278 | ERLIN2
Type: gene
Organism: cattle
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Gene
426769 | ERLIN2
Type: gene
Organism: chicken
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Gene
100151163 | erlin2
Type: gene
Organism: zebrafish
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Gene
698126 | ERLIN2
Type: gene
Organism: macaque, rhesus
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Protein Coding Gene
MGI:2387215 | Erlin2
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
17502376 | J:123599
First Author: Pearce MM
Year: 2007
Journal: J Biol Chem
Title: SPFH2 mediates the endoplasmic reticulum-associated degradation of inositol 1,4,5-trisphosphate receptors and other substrates in mammalian cells.
Volume: 282
Issue: 28
Pages: 20104-15
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Publication
19240031 | J:149249
First Author: Pearce MM
Year: 2009
Journal: J Biol Chem
Title: An endoplasmic reticulum (ER) membrane complex composed of SPFH1 and SPFH2 mediates the ER-associated degradation of inositol 1,4,5-trisphosphate receptors.
Volume: 284
Issue: 16
Pages: 10433-45
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Publication
35568199 | J:347310
First Author: Gao X
Year: 2022
Journal: J Biol Chem
Title: Binding of the erlin1/2 complex to the third intralumenal loop of IP(3)R1 triggers its ubiquitin-proteasomal degradation.
Volume: 298
Issue: 6
Pages: 102026
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Protein Coding Gene
MGP_CAROLIEiJ_G0030941 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0033499 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0033479 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0033404 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0033475 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0033189 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_2387215 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0033991 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0032515 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0033164 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0033319 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0033263 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0033408 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0033306 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0034010 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0032226 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0032631 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0021411 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0032060 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
25977983 | J:223306
   
First Author: Yang B
Year: 2015
Journal: Elife
Title: The critical role of membralin in postnatal motor neuron survival and disease.
Volume: 4
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Publication
24217618 | J:208296
First Author: Huber MD
Year: 2013
Journal: J Cell Biol
Title: Erlins restrict SREBP activation in the ER and regulate cellular cholesterol homeostasis.
Volume: 203
Issue: 3
Pages: 427-36
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Publication
22771797 | J:201292
First Author: Teranishi Y
Year: 2012
Journal: Biochem Biophys Res Commun
Title: Erlin-2 is associated with active γ-secretase in brain and affects amyloid β-peptide production.
Volume: 424
Issue: 3
Pages: 476-81
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Publication
23884412 | J:203544
First Author: Schulman JJ
Year: 2013
Journal: J Biol Chem
Title: The Bcl-2 protein family member Bok binds to the coupling domain of inositol 1,4,5-trisphosphate receptors and protects them from proteolytic cleavage.
Volume: 288
Issue: 35
Pages: 25340-9
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Publication
18468998 | J:138112
First Author: Lyssand JS
Year: 2008
Journal: J Biol Chem
Title: Blood pressure is regulated by an alpha1D-adrenergic receptor/dystrophin signalosome.
Volume: 283
Issue: 27
Pages: 18792-800
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Publication
16919269 | J:112701
First Author: Bailey PJ
Year: 2006
Journal: Exp Cell Res
Title: A global genomic transcriptional code associated with CNS-expressed genes.
Volume: 312
Issue: 16
Pages: 3108-19
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Publication
- | J:77000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: MGC Data curation in Mouse Genome Informatics
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Publication
30973865 | J:274872
First Author: Ingham NJ
Year: 2019
Journal: PLoS Biol
Title: Mouse screen reveals multiple new genes underlying mouse and human hearing loss.
Volume: 17
Issue: 4
Pages: e3000194
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Publication
10725249 | J:60984
First Author: Ko MS
Year: 2000
Journal: Development
Title: Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development.
Volume: 127
Issue: 8
Pages: 1737-49
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Publication
- | J:81858
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: Data Curation Using Mouse Genome Assembly
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Publication
- | J:57656
     
First Author: Lennon G
Year: 1999
Journal: Database Download
Title: WashU-HHMI Mouse EST Project
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Publication
- | J:204812
     
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
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Publication
- | J:155845
     
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
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Publication
- | J:211773
     
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
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Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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Publication
- | J:78475
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
38355793 | J:345621
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
30135210 | -
First Author: Wright FA
Year: 2018
Journal: J Biol Chem
Title: The erlin2 T65I mutation inhibits erlin1/2 complex-mediated inositol 1,4,5-trisphosphate receptor ubiquitination and phosphatidylinositol 3-phosphate binding.
Volume: 293
Issue: 40
Pages: 15706-15714
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Interaction Experiment
Wright FA (2018)
Description: The erlin2 T65I mutation inhibits erlin1/2 complex-mediated inositol 1,4,5-trisphosphate receptor ubiquitination and phosphatidylinositol 3-phosphate binding.
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DO Term
DOID:0110771 | hereditary spastic paraplegia 18
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Protein
F6Z6D6
Organism: Mus musculus/domesticus
Length: 59  
Fragment?: true
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Protein
E9PZB0
Organism: Mus musculus/domesticus
Length: 69  
Fragment?: false
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Publication
19751772 | -
First Author: Wang Y
Year: 2009
Journal: Biochim Biophys Acta
Title: SPFH1 and SPFH2 mediate the ubiquitination and degradation of inositol 1,4,5-trisphosphate receptors in muscarinic receptor-expressing HeLa cells.
Volume: 1793
Issue: 11
Pages: 1710-8
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Publication
22269071 | -
 
First Author: Hoegg MB
Year: 2012
Journal: BMC Cell Biol
Title: Characterization of the C. elegans erlin homologue.
Volume: 13
Pages: 2
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Protein Domain
IPR033294 | Erlin1/2
Type: Family
Description: This entry includes Erlin1/2 (also known as SPFH1/2) from animals and their homologues from plants. Mammalian Erlin1 and Erlin2 form a complex that mediates the endoplasmic reticulum-associated degradation (ERAD) of inositol 1,4,5-trisphosphate receptors (IP3Rs) such as ITPR1 [, , ]. The Erlin1/2 complex may recruit RNF170 (an E3 ubiquitin-protein ligase) to activated IP(3) receptors where it mediates IP(3) receptor ubiquitination [].Interestingly, C. elegans erlin homologue, ERL-1, does not play an essential role in the endoplasmic reticulum-associated degradation (ERAD) of inositol 1,4,5-triphosphate receptors (IP3Rs) [].
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Publication
21610068 | -
First Author: Lu JP
Year: 2011
Journal: J Biol Chem
Title: RNF170 protein, an endoplasmic reticulum membrane ubiquitin ligase, mediates inositol 1,4,5-trisphosphate receptor ubiquitination and degradation.
Volume: 286
Issue: 27
Pages: 24426-33
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Protein
A0A1B0GRG7
Organism: Mus musculus/domesticus
Length: 85  
Fragment?: true
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Protein
A0A1B0GT43
Organism: Mus musculus/domesticus
Length: 150  
Fragment?: true
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Protein
A0A1B0GRQ1
Organism: Mus musculus/domesticus
Length: 159  
Fragment?: true
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Protein
A0A1B0GT70
Organism: Mus musculus/domesticus
Length: 251  
Fragment?: true
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Protein
Q8BFZ9
Organism: Mus musculus/domesticus
Length: 340  
Fragment?: false
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Protein
Q91X78
Organism: Mus musculus/domesticus
Length: 348  
Fragment?: false
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Protein
E9PUH5
Organism: Mus musculus/domesticus
Length: 158  
Fragment?: true
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Protein
A0A1B0GQZ0
Organism: Mus musculus/domesticus
Length: 185  
Fragment?: true
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Protein
A0A1B0GSD8
Organism: Mus musculus/domesticus
Length: 220  
Fragment?: true
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